scholarly journals Antimicrobial and Antioxidant Activity of Five Medicinal Plants Against Different Microbes

2021 ◽  
Vol 18 (4) ◽  
pp. 787-794
Author(s):  
Amita Mittal ◽  
Manpreet Manpreet ◽  
Geeta Dhania
Keyword(s):  
Antioxidant Activity ◽  
Candida Albicans ◽  
Medicinal Plants ◽  
Linum Usitatissimum ◽  
Water Extract ◽  
Distilled Water ◽  
Leaf Extracts ◽  
Achyranthes Bidentata ◽  
Methanolic Extracts ◽  
Antimicrobial And Antioxidant Activity

The present study aims to assess the antimicrobial and antioxidant activity of selected medicinal plants (Achyranthes bidentata, Linum usitatissimum, Pedalium murex, Sphaeranthus indicus and, Terminalia bellirica) extracts against seven different microorganisms Candida albicans, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus hominis, and Streptococcus mutants. Leaf, root, and flower extracts of plants were prepared in different solvents like methanol, distilled water, dichloromethane, ethanol, ethyl acetate, chloroform, petroleum ether, propanol, benzene, and hexane. All the prepared extracts showed very good antimicrobial activity except distilled water extract. Most of the extracts were found to have antimicrobial potential against pathogens but Linum usitatissimum and T. bellirica leaf and seed extract prepared in methanol and chloroform solvents show a higher zone of inhibition against E. coli. Only Linum usitatissimum shows activity aganist Candida albicans. Minimum Inhibitory Concentration for Achyranthes bidentata extracts varied from 150µl/ml to 200µl/ml in different solvents. Antioxidant studies were carried out in methanolic extracts of all the plants. The maximum scavenging activity of methanolic leaf extracts was observed between 80 -100 μg/ml concentrations.

scholarly journals Antifungal properties of selected plants of Apocynaceae family against the human fungal pathogen Candida albicans

2013 ◽  
Vol 2 (7) ◽  
pp. 122-125 ◽  
Author(s):  
Savita Bajrang Wankhede ◽  
Madhushree Madhumita Routh ◽  
Sandeep Balsingh Rajput ◽  
Sankuny Mohan Karuppayil
Keyword(s):  
Candida Albicans ◽  
Fungal Pathogen ◽  
Petroleum Ether Extract ◽  
Water Extract ◽  
Pharmaceutical Journal ◽  
Nerium Oleander ◽  
Distilled Water ◽  
Leaf Extracts ◽  
Human Fungal Pathogen

The ethnobotanical evaluation of plant based chemicals has proven themselves greatly in last few decades. Plants have been a rich source of therapeutic agents and form the basis of traditional medicine system. On the basis of this, in vitro antifungal activities of extracts of Catharanthus roseus, Nerium oleander and Taberenemontana divaricata leaf extracts were evaluated in the present study by 96 well microtiter plate assays using human fungal pathogen Candida albicans ATCC90028 strain. The activity was measured by spectophotometric methods to determine the Minimum Inhibitory Concentration (MIC). The Minimum Fungicidal Concentrations (MFC) for the extracts was also determined by a plate assay. The distilled water extract, petroleum ether extract, methanolic extract, ethyl acetate extract and sequential distilled water leaf extracts of all the plants showed potential activity against C. albicans ATCC 90028. The study ascertains the value of Apocynaceae plants, which could be of considerable interest to the development of new safer antifungals.DOI: http://dx.doi.org/10.3329/icpj.v2i7.15155 International Current Pharmaceutical Journal, June 2013, 2(7): 122-125

scholarly journals Determination of Chemical Constituents and Antioxidant Activities of Leaves and Stems from Jatropha cinerea (Ortega) Müll. Arg and Jatropha cordata (Ortega) Müll. Arg

Plants ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 212
Author(s):  
Yeimi Cecilia Vega-Ruiz ◽  
Corina Hayano-Kanashiro ◽  
Nohemí Gámez-Meza ◽  
Luis Angel Medina-Juárez
Keyword(s):  
Antioxidant Activity ◽  
Antioxidant Activities ◽  
Biological Effects ◽  
Chemical Constituents ◽  
Weather Conditions ◽  
Antioxidant Compounds ◽  
Leaf Extracts ◽  
Methanolic Extracts ◽  
Northwestern Region ◽  
High Concentrations

Jatropha species have been shown to be an important source of secondary metabolites with different biological effects. Jatropha cinerea (Ortega) Müll. Arg and Jatropha cordata (Ortega) Müll. Arg are distributed in the Northwestern region of Mexico, are adapted to extreme weather conditions and are widely used (stems, leaves, and sap) in traditional medicine. The aim of the present study was to carry out the phytochemical characterization and the evaluation of the antioxidant activity in methanolic extracts of stems and leaves from J. cinerea and J. cordata. The compounds present in the extracts of both species were characterized by ESI-IT-MS/MS and quantified by HPLC-DAD. The results showed that the stem extracts of both species are rich in phenolic acids, while the leaf extracts are rich in flavonoids. Some of the main compounds found were gallic acid, gentisic acid, 3,4-Dihydroxybenzoic acid, vitexin, isovitexin, and catechol. Both species showed high concentrations of phenols and total flavonoids and antioxidant activity. J. cordata showed the highest antioxidant capacity and the highest concentration of phenolic compounds. Overall, both Jatropha species are a natural source of antioxidant compounds with potential biotechnological uses.

scholarly journals Chemical Compound of Terminalia Catappa L. as Hemostatic Agents in Post Tooth Extraction

2021 ◽  
Author(s):  
Ni Made Sirat ◽  
Asep Arifin Senjaya
Keyword(s):  
Antioxidant Activity ◽  
Tooth Extraction ◽  
Activity Index ◽  
Water Extract ◽  
Tree Height ◽  
Ethanol Extract ◽  
Chemical Compounds ◽  
Distilled Water ◽  
Terminalia Catappa ◽  
Herbal Plants

Terminalia catappa L. is one of the herbal plants that contain flavonoids that play a role in wound healing including to bleeding after tooth extraction. The aim of our study was to identify the chemical compounds contained in Terminalia catappa L. leaves. This type of research was experimental. The sample in this study was the leaves of Terminalia catappa number 3-6 from the base, at a tree height of 6 meters picked as much as 6 kilograms. Data analysis qualitatively and quantitatively. The highest content in ethanol extract of Terminalia catappa L of saponins and alkaloids were fractioned with distilled water and the lowest content were fractioned with hexane. Meanwhile distilled water is also used to fractioned the highest content of tannins and phenol. While ethyl acetate was used to fractioned the lowest content of tannins and the highest content of flavonoid. The lowest flavonoid in distilled water extract was fractioned using hexane. For the lowest content of phenol was fractioned using hexane. The results show the highest content of saponins is 3,787.80 mg/100g, the lowest is 166.67 mg/100g. The highest content of Alkaloids is 1,798.57 mg/100g, and the lowest is 576.80 mg/100g. The highest content of tannins is 53,140.72 mg/100g, the lowest is 8,391,803 mg/100g. The highest content of flavonoids is 2,5964.14 mg/100g, the lowest flavonoid is 462.84 mg/100g. The highest content of phenol 29,968.05 mg/100g, the lowest is 225.46 mg/100g. The highest antioxidant activity with AAI (Antioxidant Activity Index) obtains value of 0.36. This shows the moderate antioxidant ability. Terminalia catappa L. contain saponins, alkaloids, tannins, flavonoids, and triterpenoids. The active compound of Terminalia catappa L will generally be produced optimally if a polar solvent is used.

scholarly journals Pigments, Polyphenols and Antioxidant Activity of Leaf Extracts from Four Wild Rose Species Grown in Sicily

2018 ◽  
Vol 46 (2) ◽  
pp. 402-409 ◽  
Author(s):  
Francesca D'ANGIOLILLO ◽  
Michele Massimo MAMMANO ◽  
Giancarlo FASCELLA
Keyword(s):  
Antioxidant Activity ◽  
Morphological Characteristics ◽  
Natural Antioxidants ◽  
Total Flavonoids ◽  
Leaf Extracts ◽  
Methanolic Extracts ◽  
Dpph Method ◽  
Total Anthocyanins ◽  
Total Flavonoids Content ◽  
Promising Source

Leaf methanolic extracts of four wild Rose species (Rosa canina L., R. corymbifera Borkh., R. micrantha Borrer ex Sm and R. sempervirens L.) grown in Sicily were analysed in order to evaluate differences among indigenous roses which could be used such as source of bioactive compounds and natural antioxidants. Leaves were harvested during two different periods (June and October) and their morphological characteristics were described. Leaf content of chlorophylls, total anthocyanins, total flavonoids, total polyphenols (Folin-Ciocalteu method) and antioxidant activity (DPPH method) were determined. Results showed that the contents of chlorophylls and carotenoids were higher in leaves of all species harvested in June than in those harvested in October. On the contrary, total anthocyanins of R. micrantha and R. corymbifera leaves were higher in October. Total polyphenol content was higher in leaves of all species were harvested in October. No difference in total flavonoids content was recorded between the two harvest periods but only among the four species. Antioxidant activity was generally high in leaf extracts of all species in both periods and, particularly, in R. micrantha leaves harvested in June. These outcomes seem to support the assessment that leaves harvested from some Sicilian wild roses may be used as promising source of healthy compounds and that their content varies with the species and harvest period.

scholarly journals The in vitro antimicrobial and antioxidant activity of leaves of medicinal plants with phytobiotic potential in animal production

2021 ◽  
Author(s):  
Roisbel Aroche ◽  
Xianren Jiang ◽  
Yordan Martínez ◽  
Román Rodríguez ◽  
Xilong Li ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Medicinal Plants ◽  
Secondary Metabolites ◽  
Moringa Oleifera ◽  
Psidium Guajava ◽  
Anacardium Occidentale ◽  
Morinda Citrifolia ◽  
Bacterial Strains ◽  
Antimicrobial And Antioxidant Activity

Abstract Little is known about which secondary metabolites are responsible for inhibiting pathogenic bacteria and reducing the pro-oxidant effect on the leaves of four medicinal plants used as phytobiotic in animal production. The aim of this study was to evaluate the antimicrobial and antioxidant activity of four medicinal plants (Anacardium occidentale, Psidium guajava, Morinda citrifolia and Moringa oleifera.) in vitro. A total of six bacterial strains were inoculated, then minimum bactericidal concentration (MBC) was evaluated in fine powder and minimum inhibitory concentration (MIC) and MBC were determined on the aqueous extract. Also, the in vitro antioxidant activity was evaluated through 1,1-diphenyl-2-picryl-hydrazyl, as well as the main secondary metabolites were identified and quantified by chromatographic analysis. The results showed that Anacardium occidentale and Psidium guajava leaves had higher antimicrobial activity against all bacterial strains. In addition, Morinda citrifolia inhibited S. aureus in the aqueous extract, although without in vitro bactericidal effect, while Moringa oleifera leaf did not show antimicrobial effect. All plants showed antioxidant capacity, standing out Anacardium occidentale and Psidium guajava. Mainly the leaves of Anacardium occidentale showed high concentrations of quercetin 3-O-glucoside-7-O-rhamnoside, kaempeferol-7-O-glucoside, quercetin, caffeic acid, and cinnamic acid. Apparently, the antimicrobial and antioxidant activity are due to the main polyphenolic compounds identified in medicinal plants (mainly Anacardium occidentale and Psidium guajava); however, further studies are necessary to elucidate the exact mechanism.

TOTAL PHENOLS CONTENT AND ANTIOXIDANT ACTIVITY OF DIFFERENT POLARITY CRUDE EXTRACTS OF DODONAEA VISCOSA

INDIAN DRUGS ◽  
2021 ◽  
Vol 58 (08) ◽  
pp. 79-83
Author(s):  
Maisa R. Shoriqi ◽  
Salem S. Touby ◽  
Mohammad A. Hossain ◽  
Keyword(s):  
Antioxidant Activity ◽  
Antioxidant Properties ◽  
Water Extract ◽  
Total Phenols ◽  
Dodonaea Viscosa ◽  
Leaf Extracts ◽  
Coarse Powder ◽  
Dry Extract ◽  
Crude Extracts ◽  
Antioxidant Agents

Nowadays, effective medications as antioxidant agents are mandatory for a safe and sustainable environment. Dodonaea viscosa (D. viscosa) is used traditionally by the Omani people to treat rheumatism, toothaches, fever, cold, malaria, headaches, indigestion, ulcers, diarrhea, and constipation, dysmenorrheal and irregular menstruation. This study was carried out to prepare leaf extracts by different solvents and to determine their antioxidant activity and total phenols content. The selected plant was collected locally near the University Campus, Nizwa, Oman. The dried coarse powder was used for the extraction with methanol and it was defatted with water and successively partitioned with different polarity solvents with increasing solvent polarity. The total phenols content and antioxidant activity of the prepared different extracts were assessed by Folin-Ciocalteu reagent (FCR) and 2,2-diphenyl-1-picryl-hydrazyl (DPPH) methods. The total phenols content of different extracts was in the range of 3.02-249.93 mg gallic acid/g dry extract. The chloroform extract showed the maximum amount of total phenol compounds (249.93 mg GAE acid/g dry extract) and the minimum content was found in water extract (3.02 mg GAE acid/g dry extract). The leaf crude extracts were obtained to significant levels of antioxidant activity that ranged from percentage of inhibition from 33-85.92 %. The water extract and n-butanol extracts showed significant levels of antioxidant activity (85.92 % and 84.99 %) against the DPPH free radical method. In conclusion, this study showed that different polarities crude extracts of D. viscosa comprise a significant amount of phenols plus antioxidant properties and have possibilities of being potential use of the selected species for a natural source of antioxidants.

In vitro Antimicrobial and Antioxidant Activity of Immunity BoosterTea Formulation

2020 ◽  
Vol 2 (29) ◽  
pp. 14-19
Author(s):  
Zafar Mehmood
Keyword(s):  
Antioxidant Activity ◽  
Medicinal Plants ◽  
Radical Scavenging ◽  
Natural Antioxidant ◽  
Zone Of Inhibition ◽  
Test Organisms ◽  
Antimicrobial And Antioxidant Activity ◽  
Dpph Radical Scavenging ◽  
Strong Antimicrobial Activity

Abstract-Currently, there is much growing interest in the use of medicinal plants as modulators of the complex immune system. Through a number of vast researches conducted in the area, it is being explored that many of the phytochemicals in the form of alkaloids,tannins,flavonoids,terpenoids,polysaccharides, lactones, and glycoside products areresponsibletocausealterationsintheimmunomodulatory properties. Keeping in mind, the tremendous potential of the medicinal plants and their derived drugs, this study is undertaken and an immunobooster tea formulation (IMBF-01-20) was designed and in vitroantimicrobial and antioxidant activity was tested. The results showed strong antimicrobial activity of formulation(IMBF-01-20) against Staph.aureuswith diameter of zone of inhibition of 32 mm in methanol extract followed by 20 mm in E.coli. While hexane extract also showing good inhibition of test organisms followed by Ethanol extract.Considering the growing demand of natural antioxidant, IMBF-01-20 was tested for their antioxidant activity using DPPH radical scavenging assay.Antioxidant activity (93.4%) was observed in immunobooster tea formulation and revealed it as a natural antioxidant.

scholarly journals Invitro Efficacy of antioxidant activity in ethanolic and aqueous leaf extracts of Andrographis paniculata Nees and Rhinacanthus nasutus Kurz

2020 ◽  
Vol 11 (4) ◽  
pp. 6301-6306
Author(s):  
Akilandeswari G ◽  
Bupesh G ◽  
Vijaya Anand A ◽  
Saradhadevi K M ◽  
Mayur Mausoom Phukan ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Medicinal Plants ◽  
Radical Scavenging ◽  
The Body ◽  
Andrographis Paniculata ◽  
Peroxide Radical ◽  
Leaf Extracts ◽  
Rhinacanthus Nasutus ◽  
In Vitro Antioxidant Activity

Plants are adundantly and are very promisive to be used as source of drugs in many diseases or infections and also it is a main agents of antioxidants which prevents the oxidative stress that are caused by the free radicals. There are numerous studies based on the pharmaceutical and classification of medicinal plants throughout the world. Leaves, fruits, roots are most frequently plant parts used in many research and studies. Here the present study was aimed to evaluate the in vitro antioxidant activity of aqueous and ethanol leaf extracts of Andrographis paniculata Nees and Rhinacanthus nasutus Kurz. Antioxidant is a substance which is used to prevent some types of cell damage in the body. Determination of their in vitro antioxidant activity were carried out by using methods such as DPPH (2,2-diphenyl-1picrylhydrazyl assay), ABTS (2,2′-azinobis (3-ethylbenzothiazolin 6-sulfonic acid assay), FRAP (ferric reducing antioxidant power assay) and SOD (super oxide anion scavenging) assay, H2O2 (hydrogen peroxide radical scavenging) assay. Moreover the ethanolic leaf extracts showed best antioxidant activity than the aqueous leaf extracts. Experimental results reveals that the leaves of A. paniculata have potent antioxidant and free radical scavenging activity than R. nasutus. Further investigation must be done for these two medicinal plants for the discovery of the bioactive compounds.

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