scholarly journals Demographic characteristics, risk factors and immunocytochemistry of p16INK4a, Ki-67, MCM5, and survivin as predictors for the progress of cervical precancer lesion

2010 ◽  
pp. 147 ◽  
Author(s):  
Junita Indarti ◽  
Mohammad F. Aziz ◽  
Bambang Sutrisna ◽  
Nuryati C. Siregar ◽  
Bethy Suryawati ◽  
...  
Keyword(s):  
Risk Factors ◽  
Demographic Characteristics ◽  
Ki 67 ◽  
Cervical Precancer ◽  
Precancer Lesion

Features of Stroke in Chinese Diabetes Patients: A Hospital-based Study

2007 ◽  
Vol 35 (4) ◽  
pp. 540-546 ◽  
Author(s):  
X-D Zhang ◽  
Y-R Chen ◽  
L Ge ◽  
Z-M Ge ◽  
Y-H Zhang
Keyword(s):  
Risk Factors ◽  
Hospital Mortality ◽  
Ischaemic Stroke ◽  
Cerebral Haemorrhage ◽  
Mortality Rates ◽  
Demographic Characteristics ◽  
Major Influence ◽  
Diabetic Patients ◽  
Clinical Factors ◽  
Patients With Diabetes

In this study, demographic characteristics, risk factors, stroke subtypes and outcome were compared in 2532 patients with and without diabetes hospitalized for first-ever stroke. Diabetes was present in 471 (18.6%) of the patients. Patients with diabetes presented more frequently with ischaemic stroke (92.1% versus 71.3%), especially lacunar infarction (41.2% versus 35.2%), compared with non-diabetics. Cerebral haemorrhage was less frequent in diabetics than non-diabetics (4.2% versus 18.1%). In-hospital mortality rates from ischaemic stroke were similar in the two groups (18.2% in diabetics and 16.9% in non-diabetics). Predictors of in-hospital mortality in diabetic patients included decreased consciousness, congestive heart failure and atrial fibrillation. In conclusion, stroke in diabetic patients was different to stroke in non-diabetic patients: in diabetics the frequency of cerebral haemorrhage was lower and the rate of lacunar infarct syndrome was higher, but in-hospital mortality from ischaemic stroke was not increased. Clinical factors evident at the onset of stroke have a major influence on in-hospital mortality and may help clinicians provide a more accurate prognosis.

scholarly journals Higher D-dimer level in the early third trimester predicts the occurrence of postpartum hemorrhage

2016 ◽  
Vol 44 (5) ◽  
Author(s):  
Naho Endo-Kawamura ◽  
Mana Obata-Yasuoka ◽  
Hiroya Yagi ◽  
Rena Ohara ◽  
Yuko Nagai ◽  
...  
Keyword(s):  
Risk Factors ◽  
Postpartum Hemorrhage ◽  
Blood Parameters ◽  
Demographic Characteristics ◽  
Activity Level ◽  
Late Gestation ◽  
Antithrombin Activity ◽  
Estimated Blood Loss ◽  
Independent Risk Factors ◽  
D Dimer

AbstractThis study aimed to determine effective predictive factors for primary postpartum hemorrhage (PPH) among clinical blood parameters associated with coagulation and fibrinolysis and demographic characteristics.We retrospectively studied 1032 women who underwent determinations of clinical blood parameters at gestational week (GW) 29–32 and GW 35–37 and gave birth to singleton infants at our hospital between January 2011 and December 2013. PPH was defined as estimated blood loss ≥700 mL. Multivariate logistic regression analyses were used to determine independent risk factors and odds ratios (OR) for PPH.PPH occurred in 104 of 1032 women (10%). Three blood variables, fibrinogen level <4.0 g/L (OR [95% CI], 1.96 [1.18–3.27]), antithrombin activity <85% of normal activity level (1.84 [1.05–3.21]), and D-dimer level >2.7 μg/mL (2.03 [1.29–3.19]) at GW 35–37, and three demographic characteristics, maternal age ≥35 years (1.75 [1.15–2.68]), BMI >28.2 kg/mAmong blood parameters, higher D-dimer levels and lower levels of antithrombin activity and fibrinogen in late gestation were independent risk factors for PPH.

scholarly journals Pregnant women and risk factors: a cross-sectional study

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
V L a Fauci ◽  
R Squeri ◽  
C Genovese ◽  
V Alessi ◽  
A Facciolà
Keyword(s):  
Risk Factors ◽  
Young Adults ◽  
Health Education ◽  
Pregnant Women ◽  
Educational Level ◽  
Demographic Characteristics ◽  
Alcoholic Beverages ◽  
High Educational Level ◽  
Significant Difference ◽  
High Educational

Abstract Background Many investigations have shown the important role played by risk factors such as tobacco and alcohol in the development of congenital anomalies. Methods Through the administration of an hoc questionnaire, we evaluated the attitude towards smoking and alcohol of a sample of 200 pregnant women at the University Hospital of Messina. The questionnaire was structured to collect information about socio-demographic characteristics, type of gynaecological assistance and their lifestyles (smoking and alcohol). Statistical analysis was performed using version 10 of StatSoftVR software. Results 14% of the women continued to smoke despite pregnancy; the majority of these were young adults, divorced, employed and with a high educational level. Correlating the smoking habit with the socio-demographic characteristics of the studied women, we found a statistically significant difference for the marital status, with a higher number of smokers among the single women (p &lt; 0.05).Moreover, we found a statistically significant difference also for the profession with a higher number of smokers in the worker women (p &lt; 0.05). About the drinking habit, the 4.3% declared to be moderate drinkers (occasional use of alcohol equal to 2-3 glasses a week) despite pregnancy, the 34.4% stated they do not drink alcohol during pregnancy and the 56% stated do not usually drink alcohol. Particularly, about the drinkers' socio-demographic characteristics, the 50% of them were 24-25 years old and the 75% were married. About the type of alcoholic beverages consumed, 86% stated they usually drink bier during the weekend. Conclusions Our study shows that the awareness of the women about the importance of these risk factors is still rather poor. In order to improve the awareness of pregnant women on the importance of avoiding these risk factors and prevent CAs, health education campaigns at various levels surely represent the public health cornerstone. Key messages In our sample 14% of the pregnant women continued to smoke and 4.3% to drink despite pregnancy and they generally were young or young adults and with a high educational level. Our results highlight the importance of continuous health education about the risk to smoke and drink during pregnancy.

Socio-demographic association of non communicable diseases’ risk factors in a representative population of school children: a cross-sectional study in Sousse (Tunisia)

2016 ◽  
Vol 29 (5) ◽  
Author(s):  
Meriam El Ghardallou ◽  
Jihene Maatoug ◽  
Imed Harrabi ◽  
Sihem Ben Fredj ◽  
Sahli Jihene ◽  
...  
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
School Children ◽  
Physical Inactivity ◽  
Cross Sectional Study ◽  
Demographic Characteristics ◽  
Excess Weight ◽  
Sectional Study ◽  
Cross Sectional ◽  
Unhealthy Diet

Abstract Introduction: A better understanding of socio-demographic characteristics of subgroups, which have a high risk to develop chronic diseases, is essential to develop more efficient interventional programs especially for youth. This study aimed to determine the association between clusters of non communicable diseases (NCDs’) risk factors and the socio-demographic characteristics among a sample of Tunisian school children. Materials and methods: We conducted, in 2013/2014, a cross-sectional study among a proportional and stratified school children sample, selected in 17 elementary public schools in Sousse (Tunisia). A cluster analysis was used to identify different NCDs risk factors clusters, based on tobacco use, physical inactivity, unhealthy diet, and excess weight. Subsequent χ2-tests were used to identify differences between the NCDs risk factors clusters in regards to socio-demographic characteristics. Results: Four clusters of NCDs risk factors were found: 1) Cluster 1: physical inactivity behavior with normal weight, 2) Cluster 2: physical inactivity behavior associated to excess weight, 3) Cluster 3: unhealthy diet associated to excess weight and low practice of physical activity, and 4) Cluster 4: smoking behavior with physical activity behavior. The pattern of cluster membership differed across sex (<10–3), school level, and socioeconomic level (<10–3) but there was no significant difference between clusters for mother’s education levels and household tenure. Conclusion: This study can have important implications for health policy and practice. Indeed, it found that many subjects have simultaneous multiple NCDs risk factors which leads to identify groups at risk and implement integrated intervention program.

scholarly journals Risk Factors for Cervical Precancer and Cancer in HIV-Infected, HPV-Positive Rwandan Women

PLoS ONE ◽  
2010 ◽  
Vol 5 (10) ◽  
pp. e13525 ◽  
Author(s):  
Kathryn Anastos ◽  
Donald R. Hoover ◽  
Robert D. Burk ◽  
Antonio Cajigas ◽  
Qiuhu Shi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cervical Precancer

Abstract WP217: Association Between Atrial Fibrillation and Spinal Cord Infarction

Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Saad A Mir ◽  
Sammy D Pishanidar ◽  
Alexander E Merkler ◽  
Babak B Navi ◽  
Hooman Kamel
Keyword(s):  
Risk Factors ◽  
Atrial Fibrillation ◽  
Spinal Cord ◽  
Aortic Surgery ◽  
Demographic Characteristics ◽  
Spinal Cord Infarction ◽  
Vascular Risk ◽  
Medicare Beneficiaries ◽  
Common Cause ◽  
Cord Injury

Introduction: Spinal cord infarction (SCI) is a rare ischemic event comprising 1% of all strokes. In many cases of SCI, the cause remains undetermined. Case reports have suggested a relationship between cardiac embolism and SCI, but the association between the most common cause of cardiac embolism, atrial fibrillation (AF), and SCI has not been evaluated. Hypothesis: AF is associated with SCI. Methods: We performed a retrospective cohort study using inpatient and outpatient claims data from 2008-2014 on a 5% sample of Medicare beneficiaries. Our predictor variable was AF, ascertained by previously validated ICD-9-CM codes. The primary outcome was SCI, defined as ICD-9-CM diagnosis code 336.1 (vascular myelopathy) among patients who underwent spinal magnetic resonance imaging to rule out a compressive lesion and who did not have a concomitant diagnosis of degenerate joint disease, the most common cause of non-traumatic compressive myelopathy. In sensitivity analyses, we also excluded SCI cases accompanied by codes for traumatic spinal cord injury, spinal cord abscess, or spinal or aortic surgery. Cox proportional hazards analysis was used to assess the relationship between AF and SCI while adjusting for demographic characteristics and vascular risk factors. Results: Among 1,638,461 patients with a mean 3.9 years of follow-up, 423,856 had AF and 22 developed SCI. The annual incidence of SCI was 8.2 (95% confidence interval [CI], 4.4-15.4) per million in patients with AF compared to 2.3 (95% CI, 1.3-4.0) per million per year in those without AF. After adjustment for demographic characteristics and vascular risk factors, AF was associated with a higher risk of SCI (hazard ratio [HR], 4.8; 95% CI, 1.7-13.6). The association between AF and SCI persisted or grew stronger after excluding those with concomitant diagnoses of spinal cord injury, spinal abscess, and spinal or aortic surgery. Conclusions: In Medicare beneficiaries, AF was associated with increased risk of subsequent SCI. These results suggest the need for a thorough evaluation of potential underlying cardioembolic sources in patients with otherwise unexplained SCI.

Risk factors of hypertension, diabetes and obesity in Italian psoriasis patients: a survey on socio-demographic characteristics, smoking habits and alcohol consumption

2009 ◽  
Vol 19 (3) ◽  
pp. 252-256 ◽  
Author(s):  
Emma Altobelli ◽  
Reimondo Petrocelli ◽  
Mara Maccarone ◽  
Gianfranco Altomare ◽  
Giuseppe Argenziano ◽  
...  
Keyword(s):  
Risk Factors ◽  
Alcohol Consumption ◽  
Demographic Characteristics ◽  
Smoking Habits ◽  
Diabetes And Obesity

scholarly journals The Analysis of Risk Factors and Clinical-Demographic Characteristics of Patients with Clostridium Dificille Infection as Well as The Outcome of Their Treatment

2016 ◽  
Vol 17 (2) ◽  
pp. 139-144
Author(s):  
Ivana Raković ◽  
Biljana Popovska Jovicic ◽  
Andriana Bukonjic ◽  
Sara Petrovic ◽  
Petar Canovic ◽  
...  
Keyword(s):  
Risk Factors ◽  
Clostridium Difficile ◽  
Clostridium Difficile Infection ◽  
Antibiotic Use ◽  
Demographic Characteristics ◽  
Medical Documentation ◽  
Hospital Treatment ◽  
Continuous Variables ◽  
Bacterial Strains ◽  
H2 Blockers

Abstract Pseudomembranous colitis is a frequent nosocomial infection associated with significant morbidity and mortality. Clostridium difficile infection incidence most frequently increases due to unreasonable antibiotic use and the appearance of new hypervirulent bacterial strains, which leads to prolonged hospitalization and an increase in the total cost of hospital treatment.This is a retrospective design study conducted at Clinical Centre Kragujevac from January to December 2014. The patient data were obtained from the protocol of the Virological Laboratory and from medical documentation. All statistical analyses were performed using the computer program SPSS. The descriptive statistical data are expressed as percentage values. Continuous variables are expressed as the arithmetic mean with the standard deviation.Clostridium difficile infection occurred more frequently with elderly patients (123 patients were over 65 years old). Out of 154 patients on antibiotic treatment, 110 patients were treated with a combination of two or more antibiotics from different pharmacological groups. The most represented antibiotics were from the cephalosporin (71.4%) and quinolone (46.3%) groups. A total of 85.8% of the patients used proton pump inhibitors and H2 blockers.Our results describe the clinical and demographic characteristics of patients with diagnosed Clostridium difficile infection. The most prevalent characteristics (age, antibiotic therapy, PPI and H2 blocker use), which other researchers have also mentioned as risk factors, were present in our study as well.

scholarly journals Duodenal Rare Neuroendocrine Tumor: Clinicopathological Characteristics of Patients with Gangliocytic Paraganglioma

2016 ◽  
Vol 2016 ◽  
pp. 1-10 ◽  
Author(s):  
Yoichiro Okubo ◽  
Tomoyuki Yokose ◽  
Osamu Motohashi ◽  
Yohei Miyagi ◽  
Emi Yoshioka ◽  
...  
Keyword(s):  
Risk Factors ◽  
Neuroendocrine Tumor ◽  
Benign Tumor ◽  
Clinicopathological Characteristics ◽  
Literature Survey ◽  
Gangliocytic Paraganglioma ◽  
Ki 67 ◽  
Node Metastasis ◽  
Rare Benign Tumor ◽  
Constant Percentage

Gangliocytic paraganglioma (GP) has been regarded as a rare benign tumor that commonly arises from the second part of the duodenum. As GP does not exhibit either prominent mitotic activity or Ki-67 immunoreactivity, it is often misdiagnosed as neuroendocrine tumor (NET) G1. However, the prognosis might be better in patients with GP than in those with NET G1. Therefore, it is important to differentiate GP from NET G1. Moreover, our previous study indicated that GP accounts for a substantial, constant percentage of duodenal NETs. In the present article, we describe up-to-date data on the clinicopathological characteristics of GP and on the immunohistochemical findings that can help differentiate GP from NET G1, as largely revealed in our new and larger literature survey and recent multi-institutional retrospective study. Furthermore, we would like to refer to differential diagnosis and clinical management of this tumor and provide intriguing information about the risk factors for lymph node metastasis on GP.

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