scholarly journals Main characteristics of dermatoglypics associated with schizophrenia and its clinical subtypes

PLoS ONE ◽  
2021 ◽  
Vol 16 (6) ◽  
pp. e0252831
Author(s):  
Oyunchimeg Norovsambuu ◽  
Altansukh Tsend-Ayush ◽  
Nasantsengel Lkhagvasuren ◽  
Sarantuya Jav
Keyword(s):  
Schizophrenic Patient ◽  
Patient Group ◽  
Ring Finger ◽  
Control Group ◽  
Ridge Count ◽  
Cross Sectional ◽  
Genetic Characteristics ◽  
Schizophrenia Group ◽  
Significant Difference ◽  
And Control

Dermatoglypic patterns are extensively investigated to apply in disease-related risk assessment due to an obvious association between morphological and genetic characteristics. In the current study, we aimed to determine whether the fingerprint and palmar patterns vary between case population with schizophrenia and general population. A cross sectional study was conducted in people diagnosed with schizophrenia (cases) and a control population between 2016 and 2019. In this study, 252 people were participated. Ink and paper method was used to evaluate the difference of fingerprints palm prints between patients with schizophrenia and participants in control group.93 participants were analyzed in schizophrenic group and 142 participants were investigated in the control group. The percentage of arches on the right ring finger was significantly different between the schizophrenic patient group and control group (p = 0.011). The whorl pattern type (U-W-U-W-W-W-W-U-W-U) was dominantly observed in both of the schizophrenic patient group and control group. A-B ridge count in schizophrenic patient group and control group produced a markedly significant difference (p<0.05). Interestingly, a strong significant difference was produced in comparing of A-B ridge count in catatonic schizophrenia group with residual schizophrenia group (p<0.005). In comparison, index of pattern intensity in control group was slightly higher than that in schizophrenic patient group. Taking together, these results showed that the dermatoglypic characteristics might be a valuable tool to describe the nature of schizophrenia and its clinical subtypes and further studies are needed in clinical application.

scholarly journals Anolunula in Fingernails among Patients Infected with HIV

2014 ◽  
Vol 2014 ◽  
pp. 1-6
Author(s):  
Pratik Gahalaut ◽  
Nitin Mishra ◽  
Sandhya Chauhan ◽  
Mir Mubashir Ali ◽  
Madhur Kant Rastogi ◽  
...  
Keyword(s):  
Hiv Infection ◽  
Cross Sectional Study ◽  
Negative Control ◽  
Hiv Positive ◽  
Control Group ◽  
Cross Sectional ◽  
Significant Difference ◽  
Stage 1 ◽  
And Control ◽  
Hiv Negative

Lunula is the white, half-moon shaped area seen in proximal ends of some nails. Though a few studies have described the nail changes that can occur in association with HIV infection, none of these paid much attention to lunula. Aims and Objectives. To study the lunula in fingernails among HIV infected patients. Materials and Methods. An observational, cross-sectional study to record presence of lunula in 168 HIV-positive patients and compare it with age and sex matched 168 healthy HIV-negative control. Anolunula (absence of lunula) in HIV-positive patients was correlated with CD4 counts, stages of HIV infection, time since patient was diagnosed as HIV-positive, and status of antiretroviral therapy. Results. Anolunula was present in significantly more fingernails in HIV-positive patients compared to HIV-negative controls. There was a highly significant difference for total anolunula (anolunula in all fingernails) in study and control group. Incidence of total anolunula was directly proportional to the stage of HIV infection, increasing progressively as the HIV infection advances from stage 1 to stage 4. Conclusion. Absence of lunula is related to not only HIV infection per se but also the stages of HIV infection.

Antibiotics and Steroids in the Treatment of Acquired Subglottic Stenosis

1983 ◽  
Vol 92 (4) ◽  
pp. 377-382 ◽  
Author(s):  
John S. Supance
Keyword(s):  
Animal Model ◽  
Subglottic Stenosis ◽  
Control Group ◽  
Cross Sectional ◽  
Procaine Penicillin ◽  
Therapy Animals ◽  
Significant Difference ◽  
Medical Regimens ◽  
And Control ◽  
Systemic Antibiotics

The efficacy of a combination of systemic antibiotics and a steroid in the prevention of acquired subglottic stenosis (ASGS) was evaluated employing a previously developed canine animal model. Thirty-five healthy, postweanling mongrel puppies aged 5 weeks were each intubated for 14 days with an uncuffed polyvinyl endotracheal tube. Twenty puppies received intramuscular dexamethasone (1 mg) daily, and procaine penicillin (100,000 IU) and dihydrostreptomycin (0.125 g) in two divided doses on the day of intubation and each day thereafter until the completion of the study. The remaining 15 puppies served as a control group and received no medical therapy. Animals from both groups were killed at 5, 7, 12, 15, 20, 30, and 56 days following intubation. Comparative examinations of the laryngotracheal complexes of treated and control dogs showed that there was no significant difference between the two groups in the ultimate degree of ASGS attained, as determined by intraluminal cross-sectional area analysis, or in the extent of the lesion as documented by gross and microscopic histology. This investigation showed that the specific systemic combination of two antibiotics and a steroid used in the study was not efficacious in the prevention of ASGS in a canine animal model; for this reason we question the benefit of analogous medical regimens employed to prevent ASGS in infants and children who require long-term endotracheal intubation.

scholarly journals Comparison of ox-LDL Levels in Diabetic Patients with Normo-, Micro-, and Macroalbuminuria with Their First Degree Relatives and the Healthy Control Group

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Parisa Behzadi ◽  
Firouzeh Torabi ◽  
Massoud Amini ◽  
Ashraf Aminorroaya
Keyword(s):  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Control Group ◽  
Diabetic Patients ◽  
Cross Sectional ◽  
First Degree Relatives ◽  
Significant Difference ◽  
Healthy Control ◽  
And Control

Oxidized low density lipoprotein (ox-LDL) is a product of oxidative stress. In this cross-sectional study, we compared the ox-LDL concentrations in diabetic patients with normoalbuminuria (n=28), microalbuminuria (n=28), and macroalbuminuria (n=28) with their first degree relatives (n=28) and healthy control people (n=31). They were selected by consecutive patient selection method. The ox-LDL level was assayed using ELISA. We measured blood pressure, lipid profile, fasting plasma glucose (FPG), and HbA1c in all groups. There was no significant difference in ox-LDL concentrations among normoalbuminuric, microalbuminuric, and macroalbuminuric diabetic groups. In diabetic patients with micro- and macroalbuminuria, ox-LDL concentration was higher than their first degree relatives (P=0.04andP=0.03) and control group (P=0.001andP=0.03, resp.). In normoalbuminuric diabetic persons, ox-LDL concentration was just higher than that of healthy people (P=0.02). There was no statistically significant difference in ox-LDL levels between normoalbuminuric diabetic patients and their first degree relatives. In conclusion, the presence and progression of albuminuria in diabetic patients are not related to ox-LDL concentration and genetic predisposition influences the plasma OX-LDL level. Larger sample size is needed to confirm this conclusion in future studies.

scholarly journals Motor development in non-microcephalic infants born to mothers with Zika Virus infection during pregnancy

2020 ◽  
Vol 27 (2) ◽  
pp. 174-179
Author(s):  
Laís Rodrigues Gerzson ◽  
Carla Skilhan de Almeida ◽  
Juliana Herrero da Silva ◽  
Lavinia Schüler-Faccini
Keyword(s):  
Motor Development ◽  
Cross Sectional Study ◽  
Control Group ◽  
Cross Sectional ◽  
Gross Motor ◽  
Gross Motor Development ◽  
Significant Difference ◽  
Z Scores ◽  
And Control ◽  
Normal Head

ABSTRACT This cross-sectional study sought to evaluate motor development in infants exposed to ZIKV born with normal head circumference (HC). Thirty one children, distributed into two groups, participated in the study: 15 whose mothers were infected by ZIKV during pregnancy, born with HC from −1.9 to +2 Z-scores, adjusted for sex and gestational age (exposed group); and 16 randomly selected infants without known prenatal exposure to ZIKV, paired by sex and age (control group). Alberta Infant Motor Scale (AIMS) was used to evaluate gross motor development. We found no significant difference between the exposed and control groups. However, considering that AIMS is a screening test that assesses only the gross motor development and the small size of our sample, infants exposed to ZIKV during pregnancy should be continuously evaluated for different aspects of their development.

scholarly journals Association of Diabetes Complications With Depression and Suicidality in Hospitalized Patients: a Multicenter Cross-sectional Study

2021 ◽  
Author(s):  
Majid Pakdin ◽  
Alireza Ebrahimi ◽  
Mohammadsaeed Gharaati Jahromi ◽  
Ali Firoozabadi
Keyword(s):  
Beck Depression Inventory ◽  
Patient Group ◽  
Suicide Ideation ◽  
Psychiatric Evaluation ◽  
Mental Health Issue ◽  
Control Group ◽  
Depression Symptoms ◽  
Diabetic Patients ◽  
Cross Sectional ◽  
Significant Difference

Abstract Background: Diabetes mellitus and depression are both considered the most prevalent diseases of the recent century. On the other hand, it is estimated that the rate of depression is nearly doubled in diabetic patients compared with the general population.Method: A total of 89 patients, who were admitted to the hospital because of the complications of the disease, were voluntarily and conveniently participated in the study. The participants were given the questionnaires of Beck Depression Inventory-2nd-edition and Beck Scale for Suicide Ideation. They were divided into two age groups: 18-50 years old and 50-75 years old. Control group, consisting of 89 individuals without any underlying disease, were randomly selected from the patients’ visitors, matched with the participants according to the age group and gender. Statistical analysis was performed between the two groups based on scores obtained. Results: Beck Depression Inventory Scale score was significantly higher, regardless of age, in the patient group compared to the control group. However, there was no significant difference between the scores of Beck Scale for Suicide Ideation between the patient group and the control group. In the patient group, it was found that among the variables, female gender, and diabetic foot were associated with higher severity of depression symptoms. Conclusion: It is vitally essential for diabetic patients to undergo periodic psychiatric evaluation. Early diagnosis of depression could help them to better cope with their mental health issue, and as a result, it will decrease risk of suicidal ideation and other consequences.

scholarly journals Platelet mass index as a novel inflammatory marker for tinnitus

2020 ◽  
Author(s):  
Ahmet Doblan ◽  
togay müderris
Keyword(s):  
Patient Group ◽  
Additional Data ◽  
Inflammatory Marker ◽  
Control Group ◽  
Control Groups ◽  
Study Objective ◽  
Significant Difference ◽  
Hematological Abnormalities ◽  
And Control ◽  
Platelet Mass

Abstract: Although there is plenty of research on the etiology and treatment of tinnitus, a definitive conclusion has not been reached in most studies. Among etiological factors, vascular and hematological abnormalities can be defined as an important cause in the evaluation of tinnitus cases, and these factors may underly many structural and functional problems. In this study, we aimed to investigate whether there was a correlation between platelet mass index (PMI) and tinnitus. To our knowledge, this is the first study exploring the effect of platelet mass on tinnitus. After reviewing the detailed medical records of 1,079 tinnitus patients that presented to our clinic between January 2019 and May 2020, the hemogram values of 177 cases meeting the study criteria were evaluated. There was no statistically significant difference between the patient and control groups in terms of mean age, gender distribution, and RBC (Red Blood Cell) neutrophil, lymphocyte, PLR and NLR levels (p>0.05). Compared to the control group, the hemoglobin and MPV levels of the patient group were statistically significantly higher (p<0.001), and the platelet level was statistically significantly lower (p=0.033). In addition, the PMI level of the patient group was significantly higher than that of the control group (p<0.001). In conclusion, the NLR, PLR and MPV values were found to be higher in the tinnitus group compared to the control group, as expected. Furthermore, the additional data for tinnitus cases showed that PMI was also observed to be significantly higher compared to the control group, indicating that the study objective was reached. PMI seems to be a predictive value for tinnitus, even in patients with MPV values lower than the normal range. Therefore, we consider that PMI is more sensitive than other markers, especially MPV in inflammatory events.

scholarly journals COMPARISON IMMUNOHISTOCHEMISTRY EXPRESSION OF DESIDUAL NATURAL KILLER (dNK) IN SEVERE PREECLAMPSIAAND NORMAL PREGNANCY

2020 ◽  
pp. 58-60
Author(s):  
MUARA P. LUBIS
Keyword(s):  
Normal Pregnancy ◽  
Cross Sectional Study ◽  
Control Group ◽  
Case Group ◽  
Vascular Endothelial ◽  
Cross Sectional ◽  
Maternal Immune System ◽  
Significant Difference ◽  
Immuno Histochemistry ◽  
And Control

Objective: Preeclampsia characterized systematically by extensive vascular endothelial dysfunction and microangiopathy on mother, dNK is very important for the success of placentation. They are the key mediator of maternal immune system interactions with fetal cells. dNK cells are also involved in the modulation of EVT and the remodeling of spiral arteries. Methods: Analytic research with cross-sectional study, with samples of pregnant women who suffer from severe PE and aterm pregnancy which came to H. Adam Malik Hospital and Networking Hospital, November 2015-April 2016. The samples are 46 women, who met the inclusion criteria. Results: Immunohistochemistry examination dNK cell in the severe PE case group and control group, statistically found p<0,05. dNK placenta expression in the severe preeclampsia case group gives an overview of expression with a mean of 2.55±2.31, while the control group of normal pregnancy had higher mean is 8.66±3.16. Conclusion: The examination of immunohistochemistry of dNK cells showed there is a significant difference in the expression of Immuno-histochemistry dNK cells between severe PE case group and non severe PE.

Determination of netrin-1 levels and its relationship with neurotoxicity in carbon monoxide poisoning

2019 ◽  
Vol 38 (5) ◽  
pp. 561-566 ◽  
Author(s):  
U Gedikli ◽  
E Emektar ◽  
SK Corbacioglu ◽  
S Dagar ◽  
H Uzunosmanoglu ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Patient Group ◽  
Carbon Monoxide Poisoning ◽  
Neurological Impairment ◽  
Neurological Involvement ◽  
Control Group ◽  
Co Poisoning ◽  
Cross Sectional ◽  
Significant Difference ◽  
Neurological Effects

Objective: The aim of the study was to assess netrin-1 levels in carbon monoxide (CO) poisoning to determine its relationship with poisoning severity and neurotoxicity. Methods: This is a cross-sectional prospective study. The patients older than 18 years with CO poisoning were included. The patients were categorized into two groups on the basis of neurological involvement. Both the patient and the control groups were sampled for netrin-1 at 0th hour, and the patient group only was sampled for netrin-1 at 4th hour. Results: A total of 84 patients and 50 healthy controls were enrolled. The median 0th hour netrin-1 level of the patient group (765.1 pg/mL (619.8-983.1) was significantly higher than the control group (484 pg/mL (376-1031.6)) ( p < 0.001). There was also a significant difference between the 0th hour and 4th hour netrin-1 (888.9 pg/mL (700.3–1175.5)) levels in the patient group ( p < 0.001).There was no significant statistical difference between patients with and without neurological involvement ( p = 0.62) and between those who underwent hyperbaric oxygen therapy (HBOT) and those who did not ( p = 0.76) with respect to 4th hour netrin-1 levels. Conclusion: The significantly higher netrin-1 levels in patients with CO poisoning, suggests that netrin-1 is elevated as a stress marker. Although there is no significant difference in netrin-1 levels in patients with neurological impairment in CO poisonings, netrin-1 may show subclinically neurological effects. Hence, we believe that netrin-1 cannot be used as a marker of poisoning severity.

scholarly journals OCT-Angiographic Findings in Intermediate Uveitis-related Refractory Macular Edema

2021 ◽  
Author(s):  
Leila Alizadeh Ghavidel ◽  
Farideh Mousavi ◽  
Hesam Sadat hashemi ◽  
Masood Bagheri
Keyword(s):  
Macular Edema ◽  
Superficial Layer ◽  
Control Group ◽  
Intermediate Uveitis ◽  
Cross Sectional ◽  
Layer Density ◽  
Significant Difference ◽  
Cystic Changes ◽  
And Control ◽  
Angiographic Findings

Abstract Objective : To assess the microvascular structure of macula in uveitic refractory macular edemaMethod:In a cross-sectional observational study fifty-five patients in all were assessed for macular microvascular structure using Optuve OCT angiography: 30 patients with intermediate uveitis-related refractory macular edema (RME group), and 25 patients with intermediate uveitis without macular edema (control group).Results:Superficial layer density in RME and control group were significantly different in whole image and parafovea (P=0.027 , P= 0.001), however there was no significant differences between the two groups in fovea superficial density (P=0.711).There was no significant difference in deep layer density between the two groups (P>0.05).Conclusion:The density of superficial vessels is lower in refractory macular edema. Micro-cystic changes in inner retina and ischemia can be the cause of alteration in superficial layer density in refractory macular edema.

scholarly journals Evaluation of coagulation parameters in patients with parathyroid adenoma

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Murat Alay ◽  
Berrak Mermit Ercek ◽  
Gulcin Miyase Sonmez ◽  
Aysegul Sakin ◽  
Rifki Ucler ◽  
...  
Keyword(s):  
Parathyroid Adenoma ◽  
Patient Group ◽  
Protein S ◽  
Control Group ◽  
Control Groups ◽  
Coagulation Parameters ◽  
Significant Difference ◽  
The Mean ◽  
The Difference ◽  
And Control

Abstract Parathyroid adenoma is responsible for 80–85% of cases of primary hyperparathyroidism. Increased fibrinogen levels in patients with adenoma may increase the risk of atherosclerosis and cardiovascular events. The aim of this study was to investigate the relationship between coagulation parameters and parathyroid adenoma. A prospective study included 28 female patients with parathyroid adenoma aged 40–88 years and 27 age-matched healthy controls. The coagulation parameters were assessed for each participant. The mean ages of the patient and control groups were 57.7 ± 10.9 and 53.3 ± 9.31 years, respectively. The mean level of protein S activity was 65.79 ± 13.78 in the patient group and 77.00 ± 15.72 in the control group, and the difference was statistically significant (p = 0.013). The mean fibrinogen levels of the patient and control groups were 338.78 ± 63.87 mg/dL and 304.30 ± 45.67 mg/dL, respectively, and a significant difference was found (p = 0.041). However, no significant difference was evident between the two groups with regard to the D-dimer (p = 0.238), aPTT (p = 0.645), INR (p = 0.406), protein C (p = 0.076), and AT-III (p = 0.180) levels. A positive correlation was observed between adenoma volume and fibrinogen in the patient group (r = 0.711, p = 0.001). The protein S levels were lower and the fibrinogen levels higher in the patients with parathyroid adenoma.

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