scholarly journals Determination of Protonation Constants of Viral Inhibitor, Aurintricarboxylic Acid in SDS and CTAB Micellar Media: A Potentiometric Study

2021 ◽  
Vol 33 (10) ◽  
pp. 2301-2305
Author(s):  
K. Bhargavi ◽  
P. Shyamala ◽  
G. Nageswara Rao

Protonation constants of a viral inhibitor, aurintricarboxylic acid were determined using potentiometric method of data acquisition followed by chemometric modelling methods of analysis in the presence of two different kinds of micellar media, CTAB, a cationic micelle and SDS, an anionic micelle. MINIQUAD75 program was used for the determination of the plausible species and their corresponding formation constants at 303 ± 0.1 K and 0.01 M ionic strength. Five formation constants were identified corresponding to five ionizable hydrogens. Species concentration distribution diagrams were generated using Origin software. Best-fit chemical models were selected on the basis of statistical parameters like standard deviation (SD), U (sum of the squares of the residuals in mass balance equations) and chi-square test. It was found that the formation constants are lower in CTAB micellar medium while there is no significant change in the presence of SDS compared to aqueous medium.

2020 ◽  
Vol 60 (3) ◽  
pp. 182-187 ◽  
Author(s):  
Neeti Kapoor ◽  
Swati Dubey Mishra ◽  
Ashish Badiye

In fingerprint analysis, the determination of hand (right or left) is one of the keys to resolving questions regarding the identity of the donor of the print. It is rare to encounter a complete set of 10-digit fingerprints from the scene of a crime. Although vital and imperative, except for a few studies on whorl patterns, the use of single-digit prints and patterns to ascertain the hand of the donor is scarcely reported in the literature. This research describes a novel approach whereby an analysis of twinned loops was carried out to identify the various parameters that may be helpful in ascertaining the hand of the donor. Bilateral rolled fingerprints from 180 healthy consenting adults belonging to a heterogeneous population of central India were collected. Out of the total of 1800 prints taken, 100 twinned loops (50 on the right hand and 50 on the left hand) were analysed. The following six parameters were considered: the slope of the flow of the apex ridges, the distance between the left delta and the ascending core, the distance between the right delta and the ascending core, mid-core position, the position of the loop and ridge tracing. On applying the chi-square test, the results were found to be statistically significant. Therefore, these parameters were found suitable for the determination of the hand from a single twinned-loop print.


2017 ◽  
Vol 5 ◽  
pp. 44-55
Author(s):  
Nabin Bahadur Adhikari

Change is indispensible for the survival of the firm. Managing change become more challenging when it includes massive human involvement. This research paper aims to investigate employee commitment towards organization and own career during the merger. For this hypothesis were set to test under some constraints. The study applied empirical approach in which a survey questionnaire was used to collect quantitative data and other statistical techniques like Chi square test, Pearson correlation was applied and conclude that there is no effect of age factor in the determination of employee commitment towards the organization. Moreover the employee commitment towards their career has relative influence to employee commitment towards organization.Janapriya Journal of Interdisciplinary Studies, Vol. 5 (December 2016), page: 44-55


2012 ◽  
Vol 30 (5_suppl) ◽  
pp. 163-163
Author(s):  
Ryo Kishimoto ◽  
Ryuta Tanimoto ◽  
Kensuke Bekku ◽  
Yasuyuki Kobayashi ◽  
Shin Ebara ◽  
...  

163 Background: To evaluate whether the systematic 10 cores prostate needle biopsy is enough for determination of NCCN risk classification (NRC), we analyzed migration of Gleason score (GS), cancer location, and NRC between pre and postoperative periods in a cohort of patients who underwent radical prostatectomy. Methods: A total of 197 patients were included in this study. These patients were divided into three groups along the number of biopsy cores: less than 10 (L), 10, and more than 10 (M). We compared between three groups about Gleason score, cancer location and NCCN risk classification change (CC) between prostate biopsy and radical prostatectomy specimen. Statistical analysis were performed with chi-square test, and multiple logistic regression with p<0.05, and Bonferroni correction with p<0.017 considered significant difference. Results: The rate of CC in L, 10, M was 55.1%, 43.0%, 26.5%, respectively. On chi-square test rates of CC were significantly different between three groups (P=0.035), but rates of Gleason score and cancer location were not. On univariate analysis, PSA (Odds rate (OR) 0.872 p<0.001), preoperative NRC (low vs. intermediate, and poor, OR 0.157 and 0.241, p<0.001), prostate volume (normal vs. mild or moderate, OR 1.989 p=0.025), the number of biopsy cores (L vs. M, OR 0.293 p=0.011), GS (6 vs. 8, OR 2.374 p=0.021) were correlated with CC. On multivariate analysis, the most important independent predictive factors for CC were preoperative NRC (low vs. intermediate, p<0.001, OR 0.198, 95% CI 0.09-0.45) and PSA (p=0.007, OR 0.903, 95%CI 0.83-0.98), but the number of biopsy cores was not associated CC significantly. Conclusions: Although multivariate analysis showed no significant difference, the more biopsy cores reduced the risk of CC. Systematic 10 core biopsy might be insufficient for accurate diagnosis and treatment decision of prostate cancer.


2014 ◽  
Vol 13 (4) ◽  
pp. 448-457
Author(s):  
Milan Kubiatko ◽  
Kristyna Balatova

The misconceptions about different scientific phenomena are persisting from childhood till adulthood and no method managed to transform it into the correct form. The study is focused on finding out the misconceptions about common facts of zoology and also human body. The respondents were 112 university students. Among these respondents were 22 science major students and the rest of the respondents were non-science majors. The number of females was 82. All respondents are potentially future teachers at elementary schools, so there is a great chance/ possibility they will teach pupils and present them the kinds of information which are investigated in this study. Research tool contained 7 items, most of them were from the field of zoology and one from the field of human anatomy. Obtained data were analysed by the proportional ratio of correct and incorrect answers and the chi-square test was used for the determination of differences between groups of variables gender and field of study. There was not found a significant difference between males and females and science major students often answered some items more. There were found many misconceptions about common facts of zoology and human body. Key words: animals, human body, misconceptions, persistence, university students.


2019 ◽  
Vol 10 (1) ◽  
pp. 39
Author(s):  
Mei Ahyanti ◽  
Purwono Purwono

<p>Skin disease is a disease that attacks the body's surface and is caused by a variety of causes. PTPN VII Business Unit Way Berulu Regency Pesawaran, Lampung company plantation, and rubber/ latex. The length of time required in the processing and the addition of chemical substances at risk against the workers. The research aims to know the risk factors of occupational skin disease occurrences in PTPN VII Business Unit Berulu Way, using design case control with the total sample as many as 73 cases and 73 controls so that the total sample is 146 people, held on June-October 2017. The determination of cases based on Medical Records that are in the health service center of the plantation (Puskesbun). The analysis is done in univariate, and bivariate using Chi-Square test. The results of the analysis concluded that there was a significant relationship between previous skin disease history (pv=0,000, OR=4,399, 95% CI=1,995-9,698), personal hygiene (pv=0,000, OR=4,100, 95% CI = 1,953 - 8,608), supply of clean water (pv=0.020, OR=2.304, 95% CI=1.187-4.472) and use of APD (pv=0.037, OR=2.177, 95% CI=1.123-4.220) with the incidence of skin diseases due to work.</p><p> </p>


Frequently in sexual crimes, certain injuries are formed on the body of the victims. The features of forensic assessment of genital injuries have been studied relatively well. Investigations of injuries located outside the genitalia are reduced only to the determination of their duration and the mechanism of formation. Attempts to identify statistical patterns in their location and other characteristics to speculate about the circumstances of their causation, were not made. This study analyzed the forensic medical expertise of the socalled «sex crimes» against female children. The total amount included 516 observations. In 245 cases, according to the investigation, physical sexual abuse took place, and in 271 cases there was no such orientation. The statistical signifi cance of the diff erences was determined using the Chi-square test. Diagnostic coeffi cients and informatively important indicators were calculated.


2021 ◽  
Vol 1 (2) ◽  
pp. 105-112
Author(s):  
Kurniawan Mokodompit ◽  
Tutik Agustini ◽  
Brajakson Siokal

Labor productivity can be affected by various factors such as shift work and overtime working , where the work shift is a method of division of time that has different working hours while overtime work or overtime working is a type of work that is done outside of normal working hours .This study aims to determine the relationship between the division of Nurse Shift and Overtime Working with Performance Productivity in the Inpatient Room of LabuangBaji Hospital in Makassar.This research is a type of Cross Sectional Study, this research was conducted by direct observation by researchers, the determination of the sample was carried out by total sampling technique with a sample size of 35 respondents who met the inclusion criteria, the relationship test was performed with the Chi-Square test with a significance level α <0.05.The results showed that there was no relationship between nurse shift with performance productivity using the Chi- Square test obtained ρ = 0, 203 and there was no relationship between overtime working with performance productivity using the chi square test obtained ρ = 0.603 . It is recommended to hospital agencies to routinely provide motivation to improve morale and work ethic so as to cause high dedication , the management also routinely conducts surveillance of nurse productivity .  


2018 ◽  
Vol 15 (1) ◽  
pp. 359 ◽  
Author(s):  
Nilgün Özbaş ◽  
Zehra Göçmen Baykara

Aim: This descriptive investigation was planned to define the level of knowledge of nurses on the care of enterally fed patients.Method: This research study was performed with 170 nurses who were working at a training and education hospital in the borders of the city of Ankara and who accepted to participate in the study. Data were collected by a data collection form which was produced by the investigators and was composed of 26 questions. The Mann-Whitney U-test, Kruskal-Wallis H-test and chi-square test were used in the analysis of the data.Findings:The mean total knowledge points of nurses on enteral tube feeding was 10,44 (Max: 18, min: 0). Nurses had more knowledge on peristomal skin problems (83,53%), feeding position (80,59%) and interventions directed on at the prevention of nausea and vomiting (73,53%). Nurses were weakest on residual volume (88,82%), pulmonary aspiration (61,76%) and tube care (56,47%). Nurses working in the intensive care unit had more knowledge on enteral tube feeding compared to nurses working at other clinics.Result: As a result of this study, nurses were found to not to have the desired level of knowledge on enteral feeding. In this context, the organization of education programs, creation of care standards by institutions and repeating the study in different groups are recommended.Extended English summary is in the end of Full Text PDF (TURKISH) file.Özet Amaç: Araştırma, hemşirelerin enteral beslenen hastaların bakımına ilişkin bilgi düzeylerinin belirlenmesi amacıyla tanımlayıcı olarak yapılmıştır.Yöntem: Araştırma, Ankara ili sınırları içinde bulunan bir eğitim ve araştırma hastanesi’nde çalışan ve çalışmaya katılmayı kabul eden 170 hemşire ile gerçekleştirilmiştir. Veriler, araştırmacılar tarafından oluşturulan 26 sorudan oluşan veri toplama formu aracılığı ile elde edilmiştir. Verilerin analizinde; Mann Whitney U Testi, Kruskal Wallis H Testi, Ki-Kare Testi kullanılmıştır.Bulgular: Araştırmada, hemşirelerin tüple enteral beslenmeye yönelik toplam bilgi puan ortalamalarının 10, 44 (Max: 18, min: 0) olduğu belirlenmiştir. Hemşirelerin stoma çevresindeki cilt problemleri (%83,53) beslenme pozisyonu (% 80,59) ve bulantı kusmayı önlemeye yönelik girişimler (%73,53) ile ilgili soruları daha fazla oranda bildikleri saptanmıştır. Hemşirelerin en çok rezidüel volüm (%88,82), pulmoner aspirasyon (%61,76) ve tüp bakımı (%56,47) ile ilgili soruları bilemedikleri saptanmıştır. Yoğun bakım ünitesinde çalışan hemşirelerin diğer klinikte çalışan hemşirelere göre tüple enteral beslenmeye ilişkin soruları daha fazla bildikleri belirlenmiştir.Sonuç: Araştırmanın sonucunda hemşirelerin enteral beslenme konusunda istendik düzeyde bilgiye sahip olmadıkları belirlenmiştir. Bu bağlamda konuya ilişkin eğitim programlarının düzenlenmesi, kurumların bakım standartlarını oluşturması ve bu çalışmanın farklı gruplarda tekrarlanması önerilmektedir.


Author(s):  
Han-Ok Ko ◽  
Jae-Boong Choi ◽  
Young-Jin Kim

During the last couple of decades, several design guidelines and codes relating to major nuclear components have been introduced and revised for risk-based design and evaluation. It is an important process to determine statistical parameters in practice, for instance, by using the traditional method of moments and Maximum Likelihood Method (MLM). Since appropriate estimation of the parameters is not easy due to mathematical complexity, a robust method adopting concepts of both Chi-Square test and genetic algorithm (GA) is proposed in this paper. The Chi-Square test is a useful technique to get the goodness-of-fit of distributions, which is represented in terms of error between observed frequencies and frequencies calculated by assumed probability density function (PDF) of certain statistical distribution. The GA is an efficient optimization algorithm to solve nonlinear optimum problems. Using the Chi-Square test, statistical parameters can be determined and transferred to an optimum problem, and then solved by the GA employing proper nonlinear objective function. Reliability of the proposed method is verified against fracture toughness test data sets of SA508 reactor pressure vessel material obtained from PCVN specimens at various temperatures. The large scatter of experimental data is examined in use of a distribution reported by Neville and Kennedy, Burr type III and XII distributions by Nadarajah and Kortz as well as well-known Weibull distribution. A systematic assessment is carried out by using the new method and its results are compared with corresponding ones derived from the traditional method. Pros and corns of the alternative distributions as well as technical findings from the statistical assessment are fully discussed to show applicability of them.


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