scholarly journals Low Lactose Milk (LLM) on Refeeding of Infantile Diarrhoea

2017 ◽  
Vol 15 (9-10) ◽  
pp. 247 ◽  
Author(s):  
Suharjono Suharjono ◽  
Sunoto Sunoto ◽  
Aswitha Boediarso ◽  
Sutoto Sutoto ◽  
Dadi E. M.
Keyword(s):  
Body Weight ◽  
Child Health ◽  
Medical School ◽  
General Hospital ◽  
The Other ◽  
Infantile Diarrhoea

Seventeen infants suffering from diarrhoea hospitalized in the Department of Child Health, Medical School University of Indonesia/Dr. Tjipto Mangunkusumo General Hospital from 10 to 31 August 1973 were refed with LLM, Almiron or SGM. LLM gives good to excellent results in refeeding of infants suffering from diarrhoea. Nine out of 17 cases were refed with LLM, where as the other 8 with Almiron or SGM as a control. Result of LLM in stopping diarrhoea was excellent in 5, good in 2, poor in 2 cases. Increase of body weight was excellent in 4 cases, good in none, poor in 5 cases. Results of Almiron or SGM in stopping diarrhoea was excellent in 1 case, good in one, poor in 6 cases. Increase of body weight was excellent in 1 case, good in none, poor in 7 cases. From these results it is recommended to give low lactose milk as refeeding on patients with infantile gastroenteritis.

scholarly journals Refeeding with Free Lactose Milk ( A1 - 110 Nestle) in Children Suffering from Gastroenteritis and Dehydration

2017 ◽  
Vol 15 (7-8) ◽  
pp. 191 ◽  
Author(s):  
Suharjono Suharjono ◽  
Sunoto Sunoto ◽  
Aswitha Boediarso ◽  
Hentyanto Hendardji ◽  
Soegiharto Soegiharto
Keyword(s):  
Body Weight ◽  
Child Health ◽  
Medical School ◽  
General Hospital ◽  
Point Of View

Forty one infants suffering from diarrhoea hospitalized in the Department of Child Health, Medical School, University of lndonesia/Dr. Tjipto Mangunkusumo General Hospital, Jakarta, from August 15, 1973 to January 15, 1974 were refed with "free lactose milk".The result is as follows :1. From the point of view of increase of body weight:27 (65.8 %) out of 41 cases were excellent.2 ( 4.9 %) out of 41 cases were good.12 (29.3 %) out of 41 cases were poor.2. From the point of view of stopping the diarrhoea :25 (60.9 %) out of 41 cases were excellent.10 (24.5 %) out of 41 was good.6 (14.6 %) out of 41 cases were poor.

scholarly journals Correlation between leukocyte aggregation score of cerebrospinal fluid and bacterial meningitis in children

2016 ◽  
Vol 44 (2) ◽  
pp. 61
Author(s):  
Meitha PE Togas ◽  
Nurhayati Masloman
Keyword(s):  
Cerebrospinal Fluid ◽  
Child Health ◽  
Bacterial Meningitis ◽  
Medical School ◽  
General Hospital ◽  
The Other ◽  
Life Threatening ◽  
Leukocyte Aggregation ◽  
The Mean ◽  
Meningitis In Children

Background Bacterial meningitis is one of life-threatening dis-eases and carries a risk of sequelae in affected children. In termsof cost and rapid differentiation between bacterial and non-bacte-rial meningitis, several tests have been proposed.Objective This study aimed to determine the use of leukocyteaggregation score (LAS) of cerebrospinal fluid (CSF) in diagnos-ing bacterial meningitis.Methods A prospective analytic study was done from October 2001to July 2002 in the Department of Child Health, Medical School,Sam Ratulangi University/ Manado General Hospital. Children pre-senting with symptoms of meningitis, aged between 28 days and13 years were enrolled. LAS was counted in percentage. Regres-sion analysis was used to determine the correlation between LASand diagnosis of bacterial meningitis.Results CSF examinations were done on 35 meningitis patients.Three patients were excluded. The remaining 32 patients com-prised of 11 with bacterial meningitis and the other 21 with non-bacterial meningitis. The mean of LAS in bacterial meningitis wassignificantly higher than that of non-bacterial meningitis (p<0.001).The cut off value of LAS to diagnose bacterial meningitis was12.35%.Conclusion LAS may be used as a fast and simple alternativediagnostic tool to confirm the diagnosis of bacterial meningitis

scholarly journals Effect of Low Lactose Milk Eiwit Melk (E.M.) on Protein Calorie Malnutrition

2017 ◽  
Vol 15 (9-10) ◽  
pp. 255 ◽  
Author(s):  
Suharjono Suharjono ◽  
I.G.N. Wila Wirya ◽  
Samsudin Samsudin ◽  
Sunoto Sunoto ◽  
Z. Sulaiman ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Body Weight ◽  
Child Health ◽  
Medical School ◽  
General Hospital ◽  
Milk Formula ◽  
Protein Calorie Malnutrition

During 1½ years, from January 1972 until July 1973, 55 P.C.M. children hospitalised in the Department of Child Health, Medical School, University of Indonesia/Dr. Tjipto Mangunkusumo General Hospital, were involved to this study. Self-prepared "Eiwit Melk (E.M.)" containing protein 2.7%, carbohydrate (lactose) 1.4%, fat 2.2% and calories 600, was used. Thirty children were treated with E.M. and 25 children as controlled, i.e. treated with E.M. + lactose 3.4% (E.M.L.). The results of the clinical trial as expressed with the increase of body weight, were excellent in 85.7% and good in 14.3%, whereas the results in the controlled group were excellent in only 9.1%, good in 36.4% and poor in 54.5%. From these excellent results, low lactose milk formula might be recommended in treating children with P.C.M.

scholarly journals A Case of Pyloric Diverticulum

2019 ◽  
Vol 32 (3-4) ◽  
pp. 96-9
Author(s):  
H. A. Tangkilisan ◽  
S. M. Salendu-Warouw
Keyword(s):  
Body Weight ◽  
Child Health ◽  
Conservative Treatment ◽  
Physical Examination ◽  
General Hospital ◽  
Good Condition ◽  
Barium Meal ◽  
Laboratory Findings ◽  
X Ray ◽  
Main Complaint

EG, an 11-year-old- Indonesian boy, 30 kg of body weight and 130 em of body length was admitted to the Department of Child Health, Gunung Wenang General Hospital Manado with pyloric diverticulum. The main complaint was sudden frequent hematemesis. The first attack of this symptom developed when he was 9 years old. Physical examination showed only tenderness in the epigastric region. The laboratory findings were normal. The diagnosis was based on the Barium meal X-ray, which showed an additional appearance in the pyloric region (prebulbar). He was treated with conservative treatment and after 10 days of hospitalization, he was discharged in good condition.

scholarly journals Results of Salmonella typhi culture in patients with suspected typhoid fever, treated in the Department of Child Health Medical School, Padjadjaran University, Hasan Sadikin General Hospital Bandung

1989 ◽  
Vol 29 (5-6) ◽  
pp. 105-11
Author(s):  
Nanan Sekarwana ◽  
Herry Garna ◽  
Azhali M. S.
Keyword(s):  
Bone Marrow ◽  
Child Health ◽  
Blood Culture ◽  
Typhoid Fever ◽  
Medical School ◽  
General Hospital ◽  
Salmonella Typhi ◽  
The Third ◽  
Significant Difference ◽  
Vaccination History

From October to December 1984, examination has been carried out on Salmonella typhi cultures from blood, bone marrow, faeces and urine of 43 patients suffering from suspected typhoid fever treated in the Department of Child Health, Medical Schooll Hasan Sadikin General Hospital, Bandung.It was apparent that among these 43 patients, 51.2% were males and 48.8% females. The greater number of them were more than 5 years old (64.4%). The results of Salmonella typhi cultures were obtained  from 65% of the patients, consisting of 65% positive cultures from bone-marrow and 40% positive cultures from blood that showed a statistically significant difference (p < 0.05).Likewise, the time for matter-sampling for the examinations was based on the culture results, both on blood-culture and that of bone-marrow, statistically a significant was found (p < 0.05), whereas the results of cultures based on previous vaccination history and the administration of chloramphenicol prior to treatment did not differ significantly.It was obviously clear that the results of bone-marrow culture were more successful compared to those from blood culture, so that it should necessarily be emphasized, as to these examinations on culture from each patient with suspected typhoid fever, especially those patients hospitalized during the third week of their illness.

scholarly journals Conjunctival Mycobacteriosis

2019 ◽  
Vol 33 (7-8) ◽  
pp. 182-90
Author(s):  
Nastiti N. Rahajoe ◽  
Darmawan B. Setyanto ◽  
Muhammad Rhum ◽  
Tetty A. Usman
Keyword(s):  
Body Weight ◽  
Mycobacterium Tuberculosis ◽  
Child Health ◽  
Medical School ◽  
Granulation Tissue ◽  
Histopathologic Examination ◽  
Hospital Medical School ◽  
Mycobacterium Intracellulare ◽  
Eye Surgery ◽  
First Time

A 6 1/2- year old Indonesian girl with 30 kg of body weight was consulted to the Department of Child Health, Cipto Mangunkusumo Hospital - Medical School University of Indonesia , Jakarta, for eye, surgery tolerance. At 3 1/2 years old, she came for the first time with a granulomatous tumor on her left eye. Excision was done, and histopathologic examination revealed granulation tissue corresponding to tuberculosis. The patient was referred to the Department of Child Health for further exploration. Sensitin test was positive for Mycobacterium intracellulare, not for Mycobacterium tuberculosis. The tumor reappeared twice and the last histopathologic examination revealed nonspecific granulation tissue.

Turnover and Distribution of 131Iodine-Labelled Human Fibrinogen

1964 ◽  
Vol 11 (02) ◽  
pp. 404-422 ◽  
Author(s):  
Annemarie Amris ◽  
C. J Amris
Keyword(s):  
Body Weight ◽  
Cancer Patient ◽  
Distribution Ratio ◽  
Half Life ◽  
Fibrinolytic Activity ◽  
The Other ◽  
Turnover Rates ◽  
Human Fibrinogen ◽  
Coagulation Defects ◽  
Fractional Turnover

Summary14 patients (5 diabetics with arteriosclerotic complications, 4 patients with thrombo-embolic disease, 4 with cirrhosis, coagulation defects and increased fibrinolytic activity, and 1 cancer patient) and 3 control patients were subjected to turnover studies with 13iodine labelled human fibrinogen.Half-life times in the control patients were found to be 4 days, the fractional turnover rates 19–23 per cent, of intravascular fibrinogen per day, and the absolute turnover 0.02 to 0.06 gm per day per kg. body weight. The other patient’s half-life times and turnover rates varied considerably from 0.9–5.5 days, 13–160 per cent, per day of intravascular fibrinogen and 0.02–0.4 gm per day per kg. body weight respectively.As fibrinogen unlike other proteins subjected to turnover studies, is converted to fibrin, it is not possible to measure the true intra-extravascular distribution ratio of fibrinogen. But intravascular fibrinogen could be approximated to constitute 68–99 per cent, of the total fibrinogen. There is justification in believing that fibrinogen is degradated through a continuous coagulation in equilibrium with fibrinolysis, and that the organism contains a greater mass of fibrin, the “fibrin pool”. Considerations of the turnover mechanism can however only be hypothetical.

scholarly journals Dental pulp stem cells overexpressing hepatocyte growth factor facilitate the repair of DSS-induced ulcerative colitis

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Ning Li ◽  
Yichi Zhang ◽  
Narayan Nepal ◽  
Guoqing Li ◽  
Ningning Yang ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Ulcerative Colitis ◽  
Body Weight ◽  
Stem Cell ◽  
Dental Pulp ◽  
The Other ◽  
Therapeutic Effects ◽  
Colon Injury ◽  
Treatment Groups ◽  
Hepatocyte Growth

Abstract Background Ulcerative colitis (UC) is a chronic and recurrent disease without satisfactory treatment strategies. Dental pulp stem cell (DPSC) transplantation has been proposed as a potential therapy for UC. This study aimed to investigate the therapeutic effects of the rat hepatocyte growth factor (HGF) gene transduced into DPSCs for UC. Methods The therapeutic effects of HGF-DPSCs transplanted intravenously into a rat model of UC induced by 5% dextran sulphate sodium (DSS) were compared with the other treatment groups (LV-HGF group, DPSCs group and GFP-DPSCs group). Immunofluorescence and immunohistochemistry were used to observe the localization and proliferation of HGF-DPSCs at the site of colon injury. The expression levels of inflammatory factors were detected by real-time quantitative PCR (RT-PCR) and western blotting. The oxidative stress markers were detected by ELISA. DAI scores and body weight changes were used to macroscopically evaluate the treatment of rats in each group. Results Immunofluorescence and immunohistochemistry assays showed that HGF-DPSCs homed to colon injury sites and colocalized with intestinal stem cell (ISC) markers (Bmi1, Musashi1 and Sox9) and significantly promoted protein expression (Bmi1, Musashi1, Sox9 and PCNA). Anti-inflammatory cytokine (TGF-β and IL-10) expression was the highest in the HGF-DPSCs group compared with the other treatment groups, while the expression of pro-inflammatory cytokines (TNF-α and INF-γ) was the lowest. Additionally, the oxidative stress response results showed that malondialdehyde (MDA) and myeloperoxidase (MPO) expression decreased while superoxide dismutase (SOD) expression increased, especially in the HGF-DPSCs group. The DAI scores showed a downward trend with time in the five treatment groups, whereas body weight increased, and the changes were most prominent in the HGF-DPSCs group. Conclusions The study indicated that HGF-DPSCs can alleviate injuries to the intestinal mucosa by transdifferentiating into ISC-like cells, promoting ISC-like cell proliferation, suppressing inflammatory responses and reducing oxidative stress damage, which provides new ideas for the clinical treatment of UC.

scholarly journals Effect of Dietary Fat Composition and 2’Fucosyllactose on Neonatal Piglet Growth and Organ Lipid Composition

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1038-1038
Author(s):  
Michael Miklus ◽  
Pedro Prieto ◽  
Cynthia Barber ◽  
Robert Rhoads ◽  
Samer El-Kadi
Keyword(s):  
Fatty Acids ◽  
Body Weight ◽  
Fatty Acid ◽  
Body Weight Gain ◽  
Dietary Fatty Acids ◽  
The Body ◽  
The Other ◽  
Human Infant ◽  
Lps Challenge ◽  
Group 3

Abstract Objectives The objectives of this study were to determine the effect of 2’fucosyllactose (2’FL) and fat blends on growth, body composition and fatty acid profile of the liver and brain using the neonatal pig as a model for the human infant. Methods Pigs (3 d old) were randomly assigned to either: 1. control, 2. Palm Olein (PO) fat blend – Low 2'-FL, 3. PO – High 2'-FL, 4. High oleic acid (HO) – Low 2'-FL, 5. HO FB – High 2'-FL, 6. PO FB – GLA, or 7. kept with their sows. Pigs in groups 1 to 6 received 250 ml·kg−1·d−1 of formula in 5 equal meals for 15 d. On day 14 of the study, groups 1–6 received intraperitoneal E. coli LPS challenge at 100 µg·kg−1 weight. Results Body weight was greater for piglets fed by sows than those in the other groups (P &lt; 0.001). In addition, % fat and bone mineral content were higher in the sow-fed group while lean % was less sow-fed piglets (group 7) compared with those in the other groups (P &lt; 0.05). Only longissimus weight expressed as a % of body weight, was greater for group 7 compared with all other groups (P &lt; 0.001). Soleus, semitendinosus, brain, heart and spleen weights as a % of body weight were similar across all groups. However, liver weight as a % of body weight was greater in groups 1–6 (3.7%) compared with group 7 (2.8%; P &lt; 0.001). The proportion of brain 16:1 fatty acid was less (0.83%) for groups 1–6 than for group 7 pigs (1.08%; P &lt; 0.0001). The proportion of 20:3 N6 was greatest (0.66%) for group 3 compared with groups 1 and 4 (0.55%; P &lt; 0.05). In addition, the proportion of 20:5 N3 was greatest (0.12%) for group 3 compared with groups 1 and 7 (0.07%; P &lt; 0.05). The proportion of liver 16:1, 18:0, and 18:1 cis-11 fatty acids were greater for group 7 (2.3, 23, 2.2%) than groups 1–6 (0.2, 20, 1.2%; P &lt; 0.0001). Conversely, the contribution of 14:0, 18:1 cis-9, 18:3 N6 cis-6,9,12, and 22:6 N3 were greater for pigs in groups 1–6 (1.3, 0.6, and 14, 7.8%) compared with those in group 7 (0.5, 8.5, 0.2 and 3.5%; P &lt; 0.0001). Conclusions Our data suggest that feeding 2’fucosyllactose had no effect on the body weight gain and composition in neonatal pigs. Our data also suggest that dietary fatty acids have a greater effect on liver than on brain fatty acid composition. Funding Sources Funding for the work was provided by Perrigo Nutritionals, LLC.

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