A COMPARATIVE STUDY OF RISK FACTORS OF CARDIOVASCULAR DISEASES IN YOUNG ADULTS WITH FAMILY HISTORY OF HYPERTENSION/DIABETES MELLITUS

The most prevalent cardiovascular diseases (CVDs) are atherosclerotic, affecting all arterial territories. Epidemiologic studies such as the Framingham and INTERHEART studies have firmly established the commonest or ‘traditional’ risk factors for CVD; namely, smoking, hypertension, diabetes mellitus, hypercholesterolaemia, and a family history of CVD. The ‘risk-factors approach’ to CVD looks at these factors, individually and in combination, in the causation of disease. The complex causation pathways involve interplay of individual factors, whether genetic or environmental. More recently, there has been increasing interest in ‘epigenetics’ or the way in which the environment interacts with genes in the process underlying CVD. This chapter presents an analysis of the traditional and novel risk factors for CVD.

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Incidence of diabetes mellitus and associated risk factors in the adult population of the Basque country, Spain

Scientific Reports ◽

10.1038/s41598-021-82548-y ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Inés Urrutia ◽

◽

Alicia Martín-Nieto ◽

Rosa Martínez ◽

J Oriol Casanovas-Marsal ◽

...

Keyword(s):

Diabetes Mellitus ◽

Risk Factors ◽

Family History ◽

Basque Country ◽

Adult Population ◽

Tolerance Test ◽

Oral Glucose ◽

Family History Of Diabetes ◽

History Of ◽

Incident Cases

AbstractThe aim of this study was to estimate the incidence of diabetes mellitus in the Basque Country and the risk factors involved in the disease by reassessing an adult population after 7 years of follow-up. In the previous prevalence study, 847 people older than 18 years were randomly selected from all over the Basque Country and were invited to answer a medical questionnaire, followed by a physical examination and an oral glucose tolerance test. In the reassessment, the same variables were collected and the resulting cohort comprised 517 individuals of whom 43 had diabetes at baseline. The cumulative incidence of diabetes was 4.64% in 7 years and the raw incidence rate was 6.56 cases/1000 person-years (95%CI: 4.11–9.93). Among the incident cases, 59% were undiagnosed. The most strongly associated markers by univariate analyses were age > 60 years, dyslipidaemia, prediabetes and insulin resistance. We also found association with hypertension, obesity, family history of diabetes and low education level. Multivariate analysis adjusted for age and sex showed that a set of risk factors assessed together (dyslipidaemia, waist-to-hip-ratio and family history of diabetes) had great predictive value (AUC-ROC = 0.899, 95%CI: 0.846–0.953, p = 0.942), which suggests the need for early intervention before the onset of prediabetes.

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Sociodemographic, anthropometric and physical fitness parameters in healthy individuals with and without family history of Hypertension and/ or Type 2 Diabetes Mellitus

Journal of Medical Science And clinical Research ◽

10.18535/jmscr/v5i8.02 ◽

2017 ◽

Vol 5 (8) ◽

Author(s):

Dr Shivani Agarwal ◽

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Family History ◽

Physical Fitness ◽

Healthy Individuals ◽

Fitness Parameters ◽

History Of ◽

Family History Of Hypertension

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Faktor Risiko Terjadinya Penyakit Jantung Koroner pada Pasien di Unit Rawat Jalan Rumah Sakit Panti Rapih Yogyakarta

I Care Jurnal Keperawatan STIKes Panti Rapih ◽

10.46668/jurkes.v1i1.34 ◽

2020 ◽

Vol 1 (1) ◽

pp. 21-30

Author(s):

Deviana Widayanti ◽

Chatarina Setya Widyastuti

Keyword(s):

Diabetes Mellitus ◽

Risk Factors ◽

Coronary Heart Disease ◽

Heart Disease ◽

Family History ◽

Disease Risk ◽

Sampling Technique ◽

Excess Body Weight ◽

History Of ◽

Lack Of Exercise

Background: Coronary Heart Disease (CHD) Is a condition when the arteries that supply blood to the heart wall experience hardening and narrowing. It is estimated that 30% of coronary heart disease causes death worldwide. Objective: This study aims to determine the risk factors for CHD in Panti Rapih Hospital. Methods: This descriptive study aims to determine the risk factors for CHD in outpatients at Panti Rapih Hospital. The population is patients who have been diagnosed with coronary heart disease and the sample was taken by 50 respondents with non-random accidental sampling technique. This research take the data use questionnaire and make univariat analysis. Results: Risk factors for CHD are a number of factors that cannot be changed: family history of 42%, age = 40 years 95% in men and 95% age = 65 years in women. Factors that can be changed are: Smoking 78%, history of hypertension 68%, history of diabetes mellitus 28%, dyslipidemic 90%, excess body weight42% and lack of exercise 38%. Conclusion: Risk factors for CHD that cannot be changed: family history of 42%, age = 40 years 95% in men and 95% age = 65 years in women. Factors that can be changed are: Smoking 78%, history of hypertension 68%, history of diabetes mellitus 28%, dyslipidemic 90%, excess body weight 42% and lack of exercise 38%. Keywords: coronary heart disease, risk factors

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Study on Associated Risk Factors of Hypertension at Sipaghat of Sindhupalchowk District, Nepal

Nepalese Journal of Statistics ◽

10.3126/njs.v1i0.18818 ◽

2017 ◽

Vol 1 ◽

pp. 73-82

Author(s):

Naresh Manandhar

Keyword(s):

Risk Factors ◽

Family History ◽

Alcohol Consumption ◽

Lifestyle Modification ◽

Percent Level ◽

Cross Sectional Study ◽

Cross Sectional ◽

History Of ◽

Family History Of Hypertension ◽

Associated Risk Factors

Background: Hypertension is a progressive cardiovascular syndrome arising from complex and interrelated etiologies. Males have slightly higher prevalence than female in most of countries of Southeast-Asian region.Objective: The objective of study is to find out prevalence and the risk factors of hypertension at Sipaghat, Sindhulchowk, Nepal.Materials and Methods: A cross-sectional study was conducted at Sipaghat of Sindhupalchowk district in May 2016 and 260 persons were selected randomly. Results: The prevalence of hypertension was higher in male (25.4%) than female (17.4%). Mean age of study population was 42.08 years with standard deviation, 15.95 years. Variables namely age group, smoking, alcohol consumption and family history of hypertension were found to be significant at 5 percent level of significance. Alcohol consumption and smokers have more than two times higher chance of getting hypertension compared to alcohol non-consumer and nonsmoker with 95% confidence intervals were 1.08-4.80 and 1.21-6.10, respectively. Persons with family history of hypertension have 3.8 times more chance of getting hypertension compared to no family history of hypertension with 1.89-7.61 of 95% confidence interval.Conclusion: Lifestyle modification reduces blood pressure which prevents or delays the incidence of hypertension. Hypertension can be controlled and prevented by modifying the lifestyle. People should be advised to avoid modifiable risk factors of hypertension like smoking, consumption of alcohol and physical inactivity through health education programs.Nepalese Journal of Statistics, 2017, Vol. 1, 73-82

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A family history of risk factors and cardiovascular diseases.

Circulation ◽

10.1161/01.cir.84.3.1445 ◽

1991 ◽

Vol 84 (3) ◽

pp. 1445-1446 ◽

Cited By ~ 12

Author(s):

R M Lauer

Keyword(s):

Risk Factors ◽

Family History ◽

Cardiovascular Diseases ◽

History Of

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Cardiovascular Risk Factors in Patients with Acute MI in a Secondary Hospital in Bangladesh

Cardiovascular Journal ◽

10.3329/cardio.v12i2.47985 ◽

2020 ◽

Vol 12 (2) ◽

pp. 96-101

Author(s):

Mohammad Ullah ◽

Suman Kumar Saha ◽

Md Toufiqur Rahman ◽

Md Abdul Karim ◽

Rashid Ahmed

Keyword(s):

Risk Factors ◽

Cardiovascular Risk ◽

Family History ◽

Cardiovascular Diseases ◽

General Population ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

History Of ◽

Secondary Hospital

Background: Incidence of noncommunicable disease, specially cardiovascular diseases, is increasing in Bangladesh. Prevalence of risk factors in ischaemic heart disease (IHD) has been studied in different tertiary hospitals and institutes. This study was done in a secondary hospital with a patient population mainly of low socioeconomic condition and was compared with other patient groups of the country and Indian subcontinent. Methods: this cross sectional study was conducted in Manikganj Sadar Hospital from July 2019 to December 2019. All the patients admitted with the diagnosis of myocardial infarction (MI) were included. Cardiovascular risk factors, like smoking, diabetes mellitus (DM), hypertension (HTN), family history of premature cardiovascular diseases, dyslipidaemia and obesity, were evaluated among the patients. Results: This cross-sectional study showed most of the patients were in the age group of 50-59 years. 66% of the male patients and 2% of the female patients were smoker. 66% of the patients were hypertensive, 44% patients were diabetic, 28.5% patients were overweight, 60.4% patients had total cholesterol > 200mg/dl, 73.6% patients had LDL>130 mg/dl, 110 76.3% patients had HDL < 40 mg/ dl, 72.2% had triglyceride >150 mg/dl and 39% patients had family history of premature cardiovascular disease. Ninety (62.5%) patients had anterior MI, 50 (34.7%) patients had inferior MI and 4 (2.7%) patients had NSTEMI. 65 patients had no major risk factor and 57 % had three or more risk factors. Conclusion: The study population was more aged in comparison to other studies conducted in different parts of Bangladesh. Prevalence of smoking habit was lower but the prevalence of HTN, DM and dyslipidaemia were higher than the general population and other cohorts of MI patients. The prevalence of major risk factors was much higher than the general population of Bangladesh. Cardiovasc. j. 2020; 12(2): 96-101

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