scholarly journals OSTEOPOROZ I SERDEChNO-SOSUDISTYE ZABOLEVANIYa (SSZ) OBUSLOVLENNYE ATEROSKLEROZOM (AS) U ZhENShchIN POSTMENOPAUZAL'NOGO PERIODA:OBShchNOST' POVEDENChESKIKh I SOTsIAL'NYKh FAKTOROV RISKA

2009 ◽  
Vol 12 (2) ◽  
pp. 5-9 ◽  
Author(s):  
I A Skripnikova ◽  
R G Oganov

It is spent prospective 15 years research on studying combined pathologies (the atherosclerotic cardiovascular diseases and osteoporosis) and the general risk factors of these diseases in women at transition from reproductive in postmenopausal period. It has been shown, that the combination the atherosclerotic cardiovascular diseases and osteoporosis at postmenopausal women meets in 8 % of cases. Behavioural risk factors the atherosclerotic cardiovascular diseases, such as features ofa food, the body mass, an inactive way of life and smoking have integrated character, promoting development of both pathologies, however influence of these riskfactors on development the diseases a miscellaneous. The social status and reproductive function ofwomen make significant impact on formation of risk factors of cardiovascular diseases and osteoporosis. Timely revealing risk factors and influence on them can promote prevention both the atherosclerotic cardiovascular diseases and osteoporosis, to constrain the further development of these diseases and to reduce the economic injury put to public health services and the patient.

2005 ◽  
Vol 81 (6) ◽  
pp. 447-453 ◽  
Author(s):  
Roya Kelishadi ◽  
Gholamhossein Sadri ◽  
Ali Akbar Tavasoli ◽  
Manijeh Kahbazi ◽  
Hamid Reza Roohafza ◽  
...  

2019 ◽  
Vol 25 ◽  
pp. 107602961985942 ◽  
Author(s):  
Beata Sarecka-Hujar ◽  
Izabela Szołtysek-Bołdys ◽  
Ilona Kopyta ◽  
Barbara Dolińska ◽  
Andrzej Sobczak

Epilepsy is a disease arising from morphological and metabolic changes in the brain. Approximately 60% of patients with seizures can be controlled with 1 antiepileptic drug (AED), while in others, polytherapy is required. The AED treatment affects a number of biochemical processes in the body, including increasing the risk of cardiovascular diseases (CVDs). It is indicated that the duration of AED therapy with some AEDs significantly accelerates the process of atherosclerosis. Most of AEDs increase levels of homocysteine (HCys) as well as may affect concentrations of new, nonclassical risk factors for atherosclerosis, that is, asymmetric dimethylarginine (ADMA) and homoarginine (hArg). Because of the role of these parameters in the pathogenesis of CVD, knowledge of HCys, ADMA, and hArg concentrations in patients with epilepsia treated with AED, both pediatric and adult, appears to be of significant importance.


2019 ◽  
Vol 18 (2) ◽  
pp. 58-63
Author(s):  
I. V. Medvedenko ◽  
A. A. Safronova ◽  
E. A. Grigoricheva

Purpose of the study – to determine the relationship between the main factors of cardiovascular risk and arterial rigidity in young people.Material and methods. The evaluation of factors of cardiovascular risk and arterial rigidity in 100 people aged 22±8.3 years, followed by correlation analysis of dependence.Results. The study revealed a correlation with the body mass index, with the pulse wave velocity (r=0.36; p=0.013) and the presence of complaints of a cardiac and cerebral nature (r=0.386; p=0.011).Conclusion. Young people have a prerequisite for the development of cardiovascular diseases, based on an assessment of the combination of arterial stiffness and cardiovascular risk factors.


Author(s):  
Prem S. Singh ◽  
K. S. Zafar ◽  
Manoj Kumar ◽  
Sudhir K. Yadav

Background: Incidence and prevalence of diabetes is on surge day by day and increased longevity of diabetic patients put them at higher risk of chronic complications of hyperglycemia. Of these complications, atherosclerotic cardiovascular diseases (CVD) are of utmost importance and atherosclerotic cardiovascular diseases are the major cause of premature mortality in patients with type 2 diabetes as well. Regional variation of risk factors and sociocultural diversity of Indian population create a significant difference in atherosclerotic risk among the diabetic population across the country. There is a significant gap in the knowledge of CVD epidemiology and associated risk factors among the Indian population especially among the rural population. The objective of this study was to assess cardiovascular risk among diabetic patients of rural central India.Methods: The present cross-sectional study included 160 diabetic patients (78 males and 82 females) aged 35–75 years from the villages of district Etawah of UP, Central India. Sex-specific Framingham general cardiovascular risk prediction equations were used to calculate the 10years risk for cardiovascular disease. The probable risk factors were determined by cross-tabulation of cardiometabolic parameters with the 10-year cardiovascular risk level.Results: Males were found to be at higher risk of developing CVD in the future as compared to females with a discernible accumulation of adverse cardiovascular risk factors among them. 38.75% patients were at high risk, 37.50% at moderate risk and 23.75% at low risk for developing CVD in the next 10 years. Systolic blood pressure, total cholesterol, triglyceride and smoking contributed significantly to high degree of cardiovascular risk. Presence of cardiovascular risk factors among diabetic patients at diagnosis accentuates the need of intensive management of cardiovascular complications taking into consideration the traditional dietary pattern of the rural population.Conclusions: Both diabetes and CVD have common genetic and environmental antecedents. Furthermore, insulin resistance preceding long before the diagnosis of diabetes enhances atherogenic risk profile and has been delineated as a potential cause for subsequent increased risk of CVD among diabetic patients. There is need of intensive management of cardiovascular risk factors among diabetic individuals. Therefore, there is a need of a comprehensive study design which includes various factors (biological, sociodemographic and genetic) which directly or indirectly influence the disease incidence especially in a country (India) with diverse ethnic population.


2021 ◽  
pp. 263246362110016
Author(s):  
S. Parameshwara ◽  
B. Manjula ◽  
Geetha Bhaktha ◽  
K. Gurupadappa ◽  
G.K. Ranjith Kumar

Background: The morbidity and mortality rate is increasing due to cardiovascular disease around the globe. This may be due to drastic changes in lifestyle, food habits, work, stress, genetic factors, and environmental conditions. The present study is undertaken to evaluate the risk factors of cardiovascular disease (CVD) in Shimoga region. Objective: Evaluation of risk factors of CVD in patients who admitted for treatment in McGann Teaching District Hospital, Shimoga. Methods: A retrospective study was conducted in Mc Gann's Teaching District Hospital, Shimoga from October 2017 to March 2018. Data about sociodemographic parameters such as age, sex, height, weight, smoking, the status of diabetes mellitus, type of occupation, and diet, tobacco, and alcohol consumption were retrieved from the medical record section and statistical analysis was done using Statistical Package for the Social Sciences (SPSS). Results: Out of 262 CVD cases, 60% were male and 40% were female. Based on the body mass index (BMI), 1.9% were underweight, 40.1% were normal, 34.4% were overweight, and 23.7% were obese. Sedentary (64.9%) lifestyle was significantly higher when compared to moderate (2.3%) and heavy (32.8%). Diabetes, smoking, tobacco, and alcohol consumption were seen to be significant while food custom was not significant among the study population ( P < .05). Conclusion: In our study, a higher percentage of CVD patients falls under normal BMI when compared to other studies. This may be due to lifestyle, socioeconomic status, ethnicity, and family hereditary. Further extensive studies should be carried out to find the main cause of CVD in Shimoga population.


2021 ◽  
Vol 10 (12) ◽  
pp. 2539
Author(s):  
Piotr Szwed ◽  
Aleksandra Gąsecka ◽  
Mateusz Zawadka ◽  
Ceren Eyileten ◽  
Marek Postuła ◽  
...  

Atherosclerotic cardiovascular diseases (ASCVD) are the major cause of mortality worldwide. Despite the continuous progress in ASCVD therapy, the residual risk persists beyond the management of traditional risk factors. Several infections including Helicobacter pylori infection, periodontal disease, and viral infections are associated with the increased risk of ASCVD, both directly by damage to the heart muscle and vasculature, and indirectly by triggering a systemic proinflammatory state. Hence, beyond the optimal management of the traditional ASCVD risk factors, infections should be considered as an important non-classical risk factor to enable early diagnosis and appropriate treatment. Here, we summarized the currently available evidence regarding the role of inflammation in ASCVD and the association between the particular infections and pathogens (Helicobacter pylori, periodontal disease, pneumonia, Cytomegalovirus, Human immunodeficiency virus, Herpes simplex virus, and severe acute respiratory syndrome coronavirus 2) on the development and progression of ASCVD. We also speculated about the potential therapeutic implications of the anti-inflammatory and anti-infective drugs on ASCVD outcomes, including drugs routinely administered in patients with ASCVD (statins, P2Y12 receptor inhibitors, and angiotensin-converting enzyme inhibitors/angiotensin receptor blockers) and novel strategies aiming at residual risk reduction (colchicine, anti-cytokine drugs, and methotrexate). Considering the emerging association between infections and ASCVD, it is crucial to determine the possible advantages of infection prevention and treatment in patients with ASCVD.


2018 ◽  
Vol 3 (3) ◽  
pp. 39-46
Author(s):  
OV V Fatenkov ◽  
VV V Simerzin ◽  
IV V Gagloeva ◽  
MA A Galkina ◽  
YaA A Panisheva ◽  
...  

This survey presents the role of endothelial dysfunction in pathogenesis of atherosclerotic cardiovascular diseases as predictor of their development. Leading risk factors of endothelial dysfunction and methods of its diagnostics are also shown. Special attention is given to non medicamental correction of endothelial function disorders and its pharmacotherapy with statins, inhibitors of angiotensin converting enzyme (ACE), calcium antagonists and other drugs.


2020 ◽  
pp. 163-178
Author(s):  
Hiroyasu Iso ◽  
Kotatsu Maruyama ◽  
Kazumasa Yamagishi

Top longevity in Japan since the 1990s was primarily due to a large reduction in the incidence of stroke and a moderate reduction in ischaemic heart disease. Such trends in cardiovascular diseases in Japan are attributable to population-level health and changes in cardiovascular risk factors, especially (a) the high but largely reduced prevalence of hypertension and smoking (in men), and (b) the low but increased or stable prevalence of high blood cholesterol and the low prevalence of overweight and diabetes. Economic development, integrated activities in public health services, and improved medical care contributed to these favourable trends for stroke and ischaemic heart disease in Japan, reducing the urban-rural inequalities in cardiovascular diseases, risk factors and behaviours. An important aspect of cardiovascular health in Japan is national resistance to westernization of diet although meat and dairy consumption has tended to increase. Growing socioeconomic gradients among the ageing population however might worsen the health inequalities in cardiovascular health, requiring urgent measures for healthy ageing.


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