PO-077 Hypoxia  exercise  improves  glucose  metabolism  in  the  overweight  and  obese  women

Objective With the increase of social pressure and the unreasonable diet structure, the proportion of the overweight and obese people is increasing. Obesity is an important factor causing many chronic diseases, such as type II diabetes, atherosclerosis, hypertension, hyperlipidemia and so on. Epidemiological studies show that the proportion of obese people in China is still high. It has seriously hindered the further development of the Chinese health. The combination of diet and exercise is effective for reducing the weight. However, this method isn’t effective for overweight and obese people. Therefore, the way to reduce weight has become a central issue for many researchers. Studies have shown that the exposure of hypoxia condition can decrease weight and exercise can promote energy consumption. Exercises in a hypoxic environment provide a new way of thinking for the prevention and treatment of obesity and national fitness, and which are also a research hotspot for weight loss. Methods The study enrolled 40 young women with overweight/obese subjects, aged 18-47 years, with no abnormal physical examination. The criterion for overweight is BMI ≥ 24 and the criterion for obesity is BMI ≥ 28. All subjects were paired according to their body weight, divided into hypoxia group and normoxia group and they exercised for 6 weeks, 3 times a week, every other day. The content of the exercise intervention includes 30 minutes strength training and 30minutes endurance training. Strength training is in front and endurance training is in the back. There are 5 minutes of warm-up and finishing activities before and after training. Strength training uses dumbbells, chooses 12RM weight, exercise with 8 actions, which are dead lift, upright row, squat, shoulder press, calf Jump, advance junge, biceps curl and triceps extension, each action 2 Group, rest between groups for 30s. Endurance training uses a treadmill with a slope of 0°, and the speed is adjusted according to the target heart rate interval. The calculation method of the target heart rate interval is (220-age)×60%～(220-age)×70%. Meanwhile, the hypoxia group wears inhaled atmospheric hypoxia equipment and they exercised in a low-oxygen condition. The oxygen content of the inhaled mixed gas is 16%; the normoxia group exercises under the normal oxygen condition. Nutritional education was given to all subjects prior to the start of exercise intervention and the personal diet was controlled as much as possible, but diet was not restricted during the intervention. Body weight was measured before and after intervention. Fasting venous blood was taken. Blood glucose (GLU), insulin (INS) and glycated hemoglobin (GHb) were measured. Insulin resistance index (HOMA-IR) was calculated. All test results were expressed as mean ± standard deviation, non-parametric Mann-Whitney U test was used for comparison between groups, and non-parametric Wilcoxon matching was used for symbol level test. The significance level was P<0.05, the level of very significant was P<0.01. Results After intervention, the fasting blood glucose level of the hypoxia group and normoxia group decreased and the hypoxia group decreased more, but there was no significant difference compared with before intervention (P>0.05). There was no significant difference between the rate and the normoxia group (P>0.05). After intervention, the GHb levels in the hypoxia group and the normoxia group decreased, but there was a significant difference between the hypoxia group and the hypoxia group (P<0.05). The difference between the normoxia group was not significant (P>0.05). There was no significant difference in the rate of GHb change between the oxygen exercise group and the normoxia group (P>0.05). After intervention, the fasting INS levels in the hypoxia group and the normoxia group decreased, but there was a significant difference between the hypoxia group and the hypoxia group (P<0.05), and the difference between the normoxia group was not significant (P>0.05). There was no significant difference in the rate of fasting INS between the hypoxia group and the normoxia group (P>0.05). The HOMA-IR of the hypoxia group and the normoxia group decreased after intervention, but there was significant difference between the hypoxia group and the hypoxia group (P<0.05) and the difference between the normoxia group was not significant (P>0.05). The HOMA-IR rate of hypoxia exercise was not significantly different from that of normoxia group (P>0.05). Conclusions Compared with the normoxia group, the hypoxia group has a more improved glycosylated hemoglobin and insulin resistance index. It suggests that the exercise intervention of the hypoxia condition may be more effective in treating obesity and preventing chronic diseases.

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PO-090 Effects of 6-week Hypoxic Exercise on Glucose Metabolism in overweight/obese Males

Exercise Biochemistry Review ◽

10.14428/ebr.v1i3.11643 ◽

2018 ◽

Vol 1 (3) ◽

Author(s):

Mingming Xu ◽

Jianmin Cao ◽

Zhipei Niu ◽

Shuo Wang

Keyword(s):

Glucose Metabolism ◽

Strength Training ◽

Endurance Training ◽

Exercise Intervention ◽

Training Session ◽

Target Heart Rate ◽

Significant Difference ◽

Before And After ◽

Normal Environment ◽

Hypoxic Exercise

Objective Early studies have shown that exercise can have positive impacts on the body's glucose metabolism, but there has been no experiment revealing the different effects between normal and hypoxia, two different exercise conditions, on the glucose metabolism of adult males. The aim of this study is to expose the effects of hypoxic exercise intervention on glucose metabolism in 18-45 years old overweight/obese males. In this study, 40 males were given exercise intervention with different exercise condition. The research aims to discriminate the exercise environment that has a better influence on glucose metabolism by detecting and calculating the changes in glucose metabolism-related indicators during the different oxygen content environments exercise. Methods A parallel group design was used to study 40 healthy 18-47 years old overweight/obese males. The overweight standard is BMI≥24 and the obesity standard is BMI≥28. All 40 males were randomly divided into the hypoxia group(HG) and normal group(NG) matched on BMI and age at the pretest. The HG was provided a hypoxic exercise environment by wearing a suction-type atmospheric hypoxic device, and the oxygen content of the inhaled mixed gas is 16%; the NG was provided a normal environment. Nutritional education was given to 40 males prior to the start of exercise intervention, but diet was not restricted during exercise intervention. Both groups involved a 6-week exercise intervention which three times per week and there will be a one-day recovery time after each exercise. The intervention consists of a strength training session and an endurance training session, each intervention was generally composed of a 5minutes warm-up, 30minutes strength training, 30minute endurance training, and 5minute cooldown. The strength training contains deadlift, upright row, squat, shoulder press, calf jump, bow step, biceps curl, triceps extension, all these training loading 12RM, repeating twice and there being 0.5mins rest between sets. The treadmill was used for the endurance training, adjusting running speed according to the target heart rate interval. The calculation method of the target heart rate interval is (220-ages) ×60%~(220-ages) ×70%, and the slope is 0°. Both groups were measured body weight and taken of fasting venous blood samples, measured fasting blood glucose (GLU), glycosylated hemoglobin (GHb) and insulin (INS), calculated insulin resistance index(HOMA-IR) before and after the exercise intervention. Results After the intervention, the fasting blood GLU, INS and HOMA-IR level in the HG were significantly lower (P≤0.05). The fasting blood GLU, INS and HOMA-IR level in the NG were increased, but there was no statistically significant difference before and after the intervention (P>0.05). There was a significant difference when compared the HG with NG in the fasting blood GLU, INS and HOMA-IR level (P≤0.05). After the intervention, the GHb levels in the HG and NG both increased, but there was no significant difference compared with the pre-intervention group (P>0.05). There was no significant difference in the GHb change rate between the HG and the NG (P >0.05), either. Conclusions Through 6-week intervention, the exercise in the hypoxic environment can more effectively improve the indicators of glucose metabolism in adult obese men compared with the normal environment. The condition of hypoxic mode has more significant benign effects especially for fasting blood GLU, INS, and HOMA-IR. For the GHb results of this experiment, because this index reflects the overall glycemic control in the past 1-2 months, and this study only carried out six weeks of uncontrolled diet exercise intervention, there may be insufficient time for exercise intervention，or the long, excessive glucose intake during the intervention, resulting in no significant differences in the comparison before and after the intervention.

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Assessment of pulmonary arterial compliance evaluated using harmonic oscillator kinematics

Pulmonary Circulation ◽

10.1177/2045893217714781 ◽

2017 ◽

Vol 7 (3) ◽

pp. 666-673

Author(s):

Yasunobu Hayabuchi ◽

Akemi Ono ◽

Yukako Homma ◽

Shoji Kagami

Keyword(s):

Harmonic Oscillator ◽

Diastolic Pressure ◽

Arterial Compliance ◽

Intraclass Correlation ◽

Resistance Index ◽

Abdominal Compression ◽

Windkessel Model ◽

Significant Difference ◽

Before And After ◽

The Difference

We hypothesized that KPA, a harmonic oscillator kinematics-derived spring constant parameter of the pulmonary artery pressure (PAP) profile, reflects PA compliance in pediatric patients. In this prospective study of 33 children (age range = 0.5–20 years) with various cardiac diseases, we assessed the novel parameter designated as KPA calculated using the pressure phase plane and the equation KPA = (dP/dt_max)2/([Pmax – Pmin])/2)2, where dP/dt_max is the peak derivative of PAP, and Pmax – Pmin is the difference between the minimum and maximum PAP. PA compliance was also calculated using two conventional methods: systolic PA compliance (sPAC) was expressed as the stroke volume/Pmax – Pmin; and diastolic PA compliance (dPAC) was determined according to a two-element Windkessel model of PA diastolic pressure decay. In addition, data were recorded during abdominal compression to determine the influence of preload on KPA. A significant correlation was observed between KPA and sPAC (r = 0.52, P = 0.0018), but not dPAC. Significant correlations were also seen with the time constant (τ) of diastolic PAP (r = −0.51, P = 0.0026) and the pulmonary vascular resistance index (r = −0.39, P = 0.0242). No significant difference in KPA was seen between before and after abdominal compression. KPA had a higher intraclass correlation coefficient than other compliance and resistance parameters for both intra-observer and inter-observer variability (0.998 and 0.997, respectively). These results suggest that KPA can provide insight into the underlying mechanisms and facilitate the quantification of PA compliance.

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Effects of Aerobic Endurance Training vs HIIT on Energy Intake, Macronutrient Intake, and VO2Max Level on Fitness Centre Participants

INSPIREE: Indonesian Sport Innovation Review ◽

10.53905/inspiree.v2i3.48 ◽

2021 ◽

Vol 2 (3) ◽

pp. 179-186

Author(s):

Mury Kuswari ◽

Nazhif Gifari ◽

Aditya Himarwan

Keyword(s):

Endurance Training ◽

Energy Intake ◽

Endurance Exercise ◽

Exercise Intervention ◽

Intervention Group ◽

Interval Training ◽

T Test ◽

Macronutrient Intake ◽

Significant Difference ◽

Before And After

The purpose of the study Nowadays, there are many people who participate in fitness centre to maintain their health and fitness. There are many ways to increase VO2Max, an indicator of cardiorespiratory fitness, two of many were High-Intensity Interval Training (HIIT) and traditional aerobic endurance training. In other hand exercise in any type of way required extra energy, resulting in increased energy and macronutrient intake. Was to analyse the effects of HIIT vs. Aerobic Endurance Exercise on energy intake, macronutrient intake, and VO2Max of fitness centre participants in Depok.. Materials and methods 26 participants were recruited voluntarily from one of fitness centre in Depok, West Java, Indonesia, then randomized into HIIT Intervention Group and aerobic endurance exercise intervention group for 3 months. Energy and macronutrient intake were assessed before and after intervention. Bleep test was done to determine VO2Max Level before and after intervention. Results. Paired t-test between before and after intervention showed that there’s significant difference (p<0.05) on VO2Max, while independent sample t-test showed that there’s no significant difference between both type of exercise. Conclusions. This study shows that there was no effect of both HIIT and Aerobic Endurance Training on energy and macronutrient intake. However, both interventions increase VO2Max as an indicator of fitness level. Shorter time for HIIT may be useful for increasing VO2Max level on busy individual.

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Functional lung rejuvenation in obese patients after bariatric surgery

Revista da Associação Médica Brasileira ◽

10.1590/1806-9282.62.02.157 ◽

2016 ◽

Vol 62 (2) ◽

pp. 157-161 ◽

Cited By ~ 1

Author(s):

Saulo Maia Davila Melo ◽

Pedro Alves Argentino ◽

Murilo Matos de Santana Oliveira ◽

Gabriela Nabuco Chaves Melo ◽

Gildo Lima Souza Neto

Keyword(s):

Bariatric Surgery ◽

The Body ◽

Morbidly Obese ◽

Obese Patients ◽

Obese People ◽

Prospective Longitudinal Study ◽

Significant Difference ◽

Before And After ◽

The Difference ◽

Prospective Longitudinal

Summary Objective: To determine the lung age (LA) in obese people before and after bariatric surgery, compare the LA with the chronological age (CA) before and after the peration, and verify whether there was a functional pulmonary rejuvenation after it. Methods: A prospective longitudinal study including 43 morbidly obese patients who underwent bariatric surgery. The patients underwent clinical and spirometric evaluation in two stages, before and after the surgery. In both stages, LA, CA and spirometric variables were measured. Results: A significant improvement in the spirometric variables (FVC; FEV1; and FEV1/FVC ratio) was found after the operation (p≤ 0.0001). Comparing the LA before (50.93±13.36 years) and after the surgery (39.02±12.95 years), there was an important reduction of 11.90±9.12 years (95CI:9.10-14.71; p≤0.0001) in LA after surgery. The difference between LA and CA before surgery was 12.20± 11.71 years (95CI:8.60-15.81) with significant difference (p≤0.0001), and the difference between LA and CA after surgery was -1.95±11.83 years (95CI: -5.59-1.69) with no significant difference (p≤0.28). Regarding LA, we observed a pulmonary aging of 12.20±11.71 years before the surgery and a pulmonary rejuvenation of 11.90±9.12 years after it. Conclusion: Morbid obesity is responsible for early damage and functional accelerated pulmonary aging. After the correction of the body weight by surgery, there is a functional pulmonary rejuvenation demonstrated by the normalization of LA in relation to CA.

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PO-093 Effects of 6-week hypoxic exercise on aerobic capacity-related proteins in overweight/obese women

Exercise Biochemistry Review ◽

10.14428/ebr.v1i3.11673 ◽

2018 ◽

Vol 1 (3) ◽

Author(s):

Jun Chang ◽

Jianmin Cao ◽

Yue Yu ◽

Xu Zhang

Keyword(s):

Heart Rate ◽

Exercise Intervention ◽

Venous Blood ◽

Intervention Group ◽

Target Heart Rate ◽

Change Rate ◽

Overweight Women ◽

Significant Difference ◽

Before And After ◽

Hypoxic Group

Objective To explore the effects of hypoxic and normoxic exercise on hemoglobin (Hb), erythropoietin (EPO), hypoxia-inducible factor 1α (HIF1α) and vascular endothelial growth factor (VEGF) in overweight women. Methods This study enrolled 40 female overweight/obese subjects, age is among 18-47 years old, with no abnormal physical examination. The overweight standard is BMI ≥ 24, and the obesity standard is BMI ≥ 28. All subjects were paired according to body weight, divided into hypoxia group and normoxia group, doing 6 weeks of exercise intervention, 3 times a week, every next day one time. The exercise intervention includes 30 minutes of strength training and 30 minutes of endurance training. There are 5 minutes of warm up before training and 5 minutes cool down after the training. Strength training uses the device as a dumbbell. The training content consists of 8 movements, there are dead lift, upright row, squat, shoulder press, calf Jump, advance junge, biceps curl and triceps extension, and the weight is 12RM. 2 sets for each action, rest between sets is 30s. Endurance training uses a treadmill with a slope of 0°, and the speed is adjusted according to the target heart rate interval. The calculation method of the target heart rate interval is (220-age)×60%～(220-age)×70%. Among them, the hypoxic group is equipped with a suction-type atmospheric hypoxic device, which moves with low-oxygen environment, and the oxygen content of the inhaled mixed gas is 16%; the normoxic group moves with normal oxygen environment. Nutritional education was given to all subjects prior before the start of exercise intervention, but diet was not restricted during the intervention. Fasting venous blood was taken before and after Fasting venous blood before and after exercise intervention intervention, and Hb, EPO, HIF1α, and VEGF were detected. All the test results were expressed by mean±standard deviation (x±SD). The data between two groups were compared by non-parametric Mann-Whitney U test. The intra-group data were compared using a nonparametric Wilcoxon match for the symbol level test, with a significance level of P < 0.05 and a very significant level of P < 0.01. Results After the intervention, the Hb level in the hypoxic group was increased, but there was no significant difference compared with the pre-intervention group (P>0.05). There was no significant difference in the Hb change rate between the hypoxic group and the normoxic group (P>0.05). The EPO level in the hypoxic group was significantly increased, and there was a statistically significant difference compared with the pre-intervention group (P<0.01). There was no significant change in the EPO level in the normoxic group (P>0.05). The EPO change rate in the hypoxic group was compared with the normoxic group. There was no statistical difference (P>0.05). The level of HIF1α in the hypoxic group was significantly higher than that before the intervention (P<0.01). The level of HIF1α in the normoxic group was significantly lower than that before the intervention (P<0.01). The rate of change of HIF1α in the oxygen group was statistically different from that in the normox group (P<0.01). The level of VEGF in the hypoxic group was increased, but the level of VEGF in the normoxic group was decreased, but there was no significant difference compared with the pre-intervention group (P>0.05). There was no significant difference in the rate of VEGF in the hypoxic group compared with the normoxic group(P>0.05). Conclusions Compared with normotensive exercise, 6-week exercise increased the levels of Hb and EPO in overweight women, but the difference between hypoxia and normoxia was not significant. The level of HIF1α in the hypoxic group was increased, and the level of HIF1α in the normoxic group was decreased. This index was significantly affected by hypoxia. The level of VEGF in the hypoxic group was increased, and the level of VEGF in the normoxic group was decreased, but the effects of hypoxia and exercise were not obvious.

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Influence of Apical Patency and Cleaning of the Apical Foramen on Periapical Extrusion in Retreatment

Brazilian Dental Journal ◽

10.1590/0103-6440201302016 ◽

2013 ◽

Vol 24 (5) ◽

pp. 482-486 ◽

Cited By ~ 5

Author(s):

Marili Doro Andrade Deonizio ◽

Gilson Blitzkow Sydney ◽

Antonio Batista ◽

Roberto Pontarolo ◽

Paulo Ricardo Bittencourt Guimarães ◽

...

Keyword(s):

Material Removal ◽

Filling Material ◽

Mean Values ◽

Filtration System ◽

Root Canal Retreatment ◽

Significant Difference ◽

Before And After ◽

The Mean ◽

The Difference ◽

Removal Technique

This study evaluated the influence of apical patency, root filling removal technique and cleaning of the apical foramen, concerning the amount of debris extruded during root canal retreatment. Forty mandibular incisors were randomly assigned to 4 groups - GIM (n=10), GIIM (n=10), GIPT (n=10) and GIIPT (n=10), which were named according to leaving (I) or not (II) apical patency during canal preparation and filling removal technique (manual - M or ProTaper system - PT). After filling material removal, each specimen of each group had the apical foramen cleaned by sizes 15, 20 and 25 instruments, generating 12 subgroups: GIM15, GIM20, GIM25, GIIM15, GIIM20, GIIM25, GIPT15, GIPT20, GIPT25, GIIPT15, GIIPT20 and GIIPT25. Extruded filling debris was collected by a Milipore filtration system, an HV-durapore, 0.45 µm pore filter with a 25 mm diameter. The filters were weighed before and after the collection on an analytical scale (10–5 g), and the difference was calculated. The mean weight of extruded filling debris was analyzed statistically by Kruskal-Wallis and Friedman ANOVA tests (α=0.05). The mean values found in the groups (in mg) were: GIM (0.95±0.94), GIIM (0.47±0.62), GIPT (0.30±0.31) and GIIPT (0.32±0.44). There was no statistically significant difference among any of the groups or subgroups (p>0.05). ProTaper provided the smallest amount of extruded filling material, regardless of presence or absence of apical patency, followed by manual technique, without and with apical patency. Additional amounts of debris were collected during cleaning of the apical foramen, regardless of the instrument, presence/absence of patency or root filling removal technique.

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Doppler Flow Velocity Indices (RI, PI, S/D & PSV) of Fetal Middle Cerebral Artery in Normal Pregnancies: Correlation with Gestational Age of 20 to 40 Weeks

BIRDEM Medical Journal ◽

10.3329/birdem.v2i2.12306 ◽

2012 ◽

Vol 2 (2) ◽

pp. 77-80

Author(s):

Md Abu Taher ◽

Nuzhat Tasmin ◽

AS Mohiuddin ◽

Md Mohit Ul Alam ◽

Md Mofazzal Sharif ◽

...

Keyword(s):

Middle Cerebral Artery ◽

Flow Velocity ◽

Cerebral Artery ◽

Gestational Age ◽

Resistance Index ◽

Peak Systolic Velocity ◽

Doppler Flow ◽

Significant Difference ◽

Before And After ◽

Doppler Indices

This observational type of descriptive study was carried out in the Department of Radiology and Imaging, BIRDEM selecting 70 Bangladeshi pregnant babies with the aim to find out the normogram of foetal middle cerebral artery Doppler flow velocity indices and correlation between Doppler flow velocity indices [Resistance Index (RI), Pulsatility Index (PI), Systolic/Diastolic ratio (S/D) & Peak Systolic Velocity (PSV)] of foetal middle cerebral artery and gestational age in normal pregnancies of 20 to 40 weeks. It was observed that RI, PI and S/D were decreased with the advance of gestational age but PSV was increases with the advance of gestational age. Statistical analyses showed there were significant difference between mean PSV, RI and PI before and after 25 weeks of gestation. No significant difference was found between mean S/D before and after 25 weeks of gestation. It was observed from Correlation analysis between Doppler indices with independent gestational age that all the Doppler indices of foetal middle cerebra artery was positively correlated with the whole gestation period. The statistical analysis showed only PSV and RI were significantly correlated with the gestational age. Simple regression analysis between dependent Doppler index with independent gestational age before and after 25 weeks revealed that all the Doppler indices had positive relationship with the corresponding gestational age but relationship between PSV and PI (before 25 weeks) with their corresponding gestational ages were only statistically significant.DOI: http://dx.doi.org/10.3329/birdem.v2i2.12306 Birdem Med J 2012; 2(2) 77-80

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The difference in saliva pH before and after brushing with fluoride containing toothpaste and without toothpaste

Padjadjaran Journal of Dentistry ◽

10.24198/pjd.vol20no3.14118 ◽

2008 ◽

Vol 20 (3) ◽

Author(s):

Samuel Setiawan ◽

Edeh Rolleta Haroen ◽

Dede Hadidjah

Keyword(s):

Drinking Water ◽

Research Method ◽

Control Group ◽

Research Subjects ◽

Male And Female ◽

Significant Difference ◽

Salivary Ph ◽

Before And After ◽

Quasi Experimental ◽

The Difference

In administering fluoride through drinking water there is the risk of overdose, higher cost and inadequate availability of drinking water containing fluoride in developing countries like Indonesia. A safe fluoride source is contained in toothpaste. The purpose of this research was to obtain data concerning difference in saliva pH before and after brushing with toothpaste containing fluoride and without toothpaste. The research method used was the quasi-experimental method. Samples were collected by the way of purposive sampling, conducted on 43 male and female research subjects. The data were analyzed by statistical analysis using the t test at 95% confidence level. In this research a control group consisting of 43 people was used. Research results indicated that the average saliva pH before brushing was 7.174; after brushing with fluoride containing toothpaste salivary pH was 7.593. Result research of brushing without toothpaste showed an average saliva of 7.163 before brushing and 7.379 after brushing without toothpaste. The average changes in saliva pH before and after brushing using fluoride containing toothpaste was 0.216. The conclusion of this research was that there was significant difference in saliva pH before and after brushing with toothpaste containing fluoride; there was significant difference in saliva pH before and after brushing without toothpaste, and there was significant difference in saliva pH before and after brushing with toothpaste containing fluoride and without toothpaste.

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OHIS Differences on Primary School Students in Relation to Little Dentist Training

10.31219/osf.io/uxbks ◽

2021 ◽

Author(s):

Asep Arifin Senjaya ◽

Ni Made Sirat ◽

I Nyoman Wirata ◽

Ni Ketut Ratmini

Keyword(s):

Treatment Group ◽

Primary School ◽

Oral Hygiene ◽

Dental Health ◽

Control Group ◽

Primary School Students ◽

School Students ◽

Significant Difference ◽

Before And After ◽

The Difference

Dental healthcare is very important since dental and oral hygiene should be maintained. Statistics showed that more than 80% of children in developed and developing countries suffer from dental disease. This study aimed to see the safety of OHIS (Oral Hygiene Index Simplified) in primary school students who got and did not get little dentist cadre training in Bangli Regency in 2019. The study was done in an experimental design: pre and post-test with control design, which was conducted in August-September 2019. The sample in this study is 366 students. The difference in OHIS scores before and after treatment in the control group and treatment group was carried out by the bivariate Mann Whitney U Test. The results of the study showed that before dental health training was conducted, there were 54.3% of primary school students in the treatment group with good OHIS score criteria, and after the training was carried out as many as 98.4% of the students in the treatment group had a good OHIS. Additionally, prior to the training, 57.5% of the control group had fair OHIS criteria score. Then, after the training was carried out, 73.7% of the control group had good OHIS score. Hence, the study concluded that there was a significant difference in the OHIS of primary school students who got little doctor training prior to and after the training. Also, there was a significant difference in the OHIS of the students who did not get such treatment before and after the training.

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The Effect of Extract Supplements of Moringa Oleifera Leaves Plus Royal Jelly on Hemoglobin (Hb) Levels of Anemia Pregnant Mother in Takalar Regency

International Journal Papier Advance and Scientific Review ◽

10.47667/ijpasr.v1i2.31 ◽

2020 ◽

Vol 1 (2) ◽

pp. 22-29

Author(s):

Yulni Yulni ◽

Veni Hadju ◽

Burhanuddin Bahar ◽

Citrakesumasari Citrakesumasari ◽

Rahayu Indriasari ◽

...

Keyword(s):

Pregnant Women ◽

Leaf Extract ◽

Moringa Oleifera ◽

Royal Jelly ◽

P Value ◽

Double Blind ◽

Significant Difference ◽

Before And After ◽

The Difference ◽

Double Blind Design

The aim of this study was to determine the effect of Moringa oleifera leaf extract supplements, Moringa oleifera leaf extract plus royal jelly and placebo on hemoglobin levels in anemic pregnant women. This research is a randomized controlled double blind design study which was conducted in Polombangkeng Utara District, Takalar Regency for 2 months. The subjects of this study were pregnant women with anemia, the majority of which were 20-35 years old, primigravida parity, income less than UMR, unemployment, higher education, pregnancy distance of more than 2 years with p value> 0.05. Then divided into three groups, namely Moringa capsules plus royal jelly (KRJ) (n = 24), Moringa capsules (KTR) (n = 24) and placeco (PLC) (n = 21). Before and after the intervention, measurements of hemoglobin levels were carried out using the Hemocue tool and interviewing the characteristics of the respondents. The results showed that the average Hb level increased from each group (mean SD): KRJ 10.06 ± 0.75 to 11.42 ± 1.23, P = 0.001, KTR 10.40 ± 0.46 to 11.15 ± 0 , 90 P = 0.001 and PLC 10.43 ± 0.42 becomes 11.14 ± 0.88 P = 0.002. but there was no significant difference from the difference in the average increase in Hb levels in the three groups, but there was a tendency that KRJ was superior to the KTR and PLC groups with an increase of 1.36 gr / dl, KTR 0.75 gr / dl and PLC 0.71 gr / dl. So it can be concluded that KRJ is better than KTR and PLC in increasing Hb levels in anemic pregnant women in Takalar Regency.

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