The Effect of Extract Supplements of Moringa Oleifera Leaves Plus Royal Jelly on Hemoglobin (Hb) Levels of Anemia Pregnant Mother in Takalar Regency

The aim of this study was to determine the effect of Moringa oleifera leaf extract supplements, Moringa oleifera leaf extract plus royal jelly and placebo on hemoglobin levels in anemic pregnant women. This research is a randomized controlled double blind design study which was conducted in Polombangkeng Utara District, Takalar Regency for 2 months. The subjects of this study were pregnant women with anemia, the majority of which were 20-35 years old, primigravida parity, income less than UMR, unemployment, higher education, pregnancy distance of more than 2 years with p value> 0.05. Then divided into three groups, namely Moringa capsules plus royal jelly (KRJ) (n = 24), Moringa capsules (KTR) (n = 24) and placeco (PLC) (n = 21). Before and after the intervention, measurements of hemoglobin levels were carried out using the Hemocue tool and interviewing the characteristics of the respondents. The results showed that the average Hb level increased from each group (mean SD): KRJ 10.06 ± 0.75 to 11.42 ± 1.23, P = 0.001, KTR 10.40 ± 0.46 to 11.15 ± 0 , 90 P = 0.001 and PLC 10.43 ± 0.42 becomes 11.14 ± 0.88 P = 0.002. but there was no significant difference from the difference in the average increase in Hb levels in the three groups, but there was a tendency that KRJ was superior to the KTR and PLC groups with an increase of 1.36 gr / dl, KTR 0.75 gr / dl and PLC 0.71 gr / dl. So it can be concluded that KRJ is better than KTR and PLC in increasing Hb levels in anemic pregnant women in Takalar Regency.

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The Effect of Moringa Oleifera Leaves Plus Royal Jelly Supplement on Cortisol Hormone and Stress Levels on Anemia of Pregnant Women in Takalar Regency

Journal La Lifesci ◽

10.37899/journallalifesci.v1i3.189 ◽

2020 ◽

Vol 1 (3) ◽

pp. 30-36

Author(s):

Wilma Florensia P ◽

Veni Hadju ◽

Masyitha Muis ◽

Citrakesumasari Citrakesumasari ◽

Saifuddin Sirajuddin ◽

...

Keyword(s):

Pregnant Women ◽

Moringa Oleifera ◽

Royal Jelly ◽

T Test ◽

P Value ◽

Chi Square ◽

Double Blind ◽

A Value ◽

Stress Levels ◽

Cortisol Levels

This study aims to determine the effect of Moringa Oleifera plus Royal Jelly leaf extract supplements on stress levels and cortisol levels in anemic pregnant women. This study was a true experimental study with a controlled randomized double blind pretest-post test design. The subjects of this study were 44 pregnant women with anemia, taken based on inclusion and exclusion criteria and divided into two groups, namely the group given moringa capsules (n = 22) and moringa capsules plus royal jelly (n = 22). Data were analyzed using Chi-square test, Paired T-Test, Wilcoxon and Independent T-Test using SPSS. The result of the study shows a significant decrease in the stress level in the royal jelly moringa group from 29.23 ± 10.451 to 17.00 ± 6.325 with a value of P = 0.000 and in the moringa group from 23.59 ± 8.110 to 18.05 ± 4.498 with a value of P = 0.022. Likewise, the cortisol levels decreased significantly in the moringa royal jelly group from 41.17 ± 18.466 to 28.75 ± 15.024 with a P value = 0.002 and the moringa group from 34.54 ± 21.437 to 24.70 ± 18.218 with a P value = 0.009. However, the difference in the magnitude of change did not differ significantly for stress levels and cortisol levels (P> 0.05). It is concluded that the reduction in stress and changes in royal jelly moringa tends to be greater than that of moringa.

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Primary Dysmenorrhea Intensity Between Stretching Abdominal Therapy and Acupuncture to Adolescent Girls

Journal of Health and Medical Sciences ◽

10.31014/aior.1994.04.03.179 ◽

2021 ◽

Vol 4 (3) ◽

Author(s):

Ni Nyoman Suindri ◽

◽

Ni Luh Putu Sri Erawati ◽

Made Widhi Gunapria Darmapatni ◽

Ni Gusti Kompiang Sriasih

Keyword(s):

High School ◽

High School Students ◽

Adolescent Girls ◽

Rating Scales ◽

Wilcoxon Test ◽

P Value ◽

Menstrual Pain ◽

Significant Difference ◽

Before And After ◽

The Difference

Menstrual pain or dysmenorrhea is known as cramping pain in the lower abdomen during menstruation experienced by some women. Abdominal stretching exercises and acupressure can reduce dysmenorrhea. This research aims to determine the difference in the intensity of primary menstrual pain (dysmenorrhea) between abdominal stretching therapy and acupressure for adolescent girls in a Senior High School in Denpasar. The method applied in this research is a Quasi-Experimental two-groups pretest-posttest design. The research sample was grouped into two, namely 70 high school students in the abdominal stretching therapy and 70 students in acupressure therapy. The data were collected using the Numerical Rating Scales or NRS. The data were then analysed using the Wilcoxon test and Mann Whitney test. The result of the research showed that there was a significant difference in dysmenorrhea before and after abdominal stretching therapy (p=0.000). Also, there was a significant difference in dysmenorrhea before and after acupressure therapy (p=0.000). There was no difference in dysmenorrhea before applying abdominal stretching therapy and acupressure with a p-value=0.335. Also, there was no difference in dysmenorrhea after both therapies were undergone in two groups (p=0,111). The difference test on the difference between the pre-test and post-test obtained p-value = 0.012. Hence, there was a significant difference in decreasing dysmenorrhea between abdominal stretching therapy and acupressure (p=0.012). Conclusion: there is a significant difference in reducing dysmenorrhea between abdominal stretching therapy and acupressure. Suggestion: further research is necessary to conduct by using time series design.

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Comparative Study of the Clinical Application of 2 Bleeding Grading Systems for Pregnant Women With Immune Thrombocytopenia

Clinical and Applied Thrombosis/Hemostasis ◽

10.1177/1076029620910790 ◽

2020 ◽

Vol 26 ◽

pp. 107602962091079

Author(s):

Jianwan Huang ◽

Bangwei Zeng ◽

Xiaofan Li ◽

Meijuan Huang ◽

Rong Zhan

Keyword(s):

Pregnant Women ◽

Immune Thrombocytopenia ◽

Assessment Tool ◽

Patients Âgés ◽

Chronic Group ◽

Grading Systems ◽

Significant Difference ◽

Before And After ◽

The Difference ◽

Disease Stages

Objective: To compare the clinical practicability of two bleeding grading systems (BGS) in pregnancy with Immune Thrombocytopenia (ITP). Methods: The clinical data of 154 cases were retrospectively analyzed with the 2016 version of the ITP Bleeding Scale (ITP-2016) and the ITP-specific bleeding assessment tool (ITP-BAT). The correlation between the two BGS and the relations among the platelet counts, gestational ages, and disease stages were respectively analyzed. Results: There is no significant difference between the two BGS in the patients’ ages, nor between the newly diagnosed and the persistent group or the chronic group, while the difference between the persistent and the chronic group was significant ( P = 0.001; P = 0.001). There is a negative correlation between the bleeding grade and platelet count (r = -0.436; r = -0.390), while the correlation between the two BGS was positive (r = 0.921). The proportions of identical scores provided by two different physicians using the two BGS were 94.8% and 93.5%. The difference before and after the treatment were significantly different ( P = 0.013; P = 0.037). It takes less time to score with the ITP-2016 ( P = 0.011). Conclusion: Both systems can be useful for disease evaluations, risk assessments and efficacy evaluations in Chinese pregnant women with ITP. The ITP-2016 takes less time and is more suitable for Chinese pregnant patients with ITP.

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A single dose of beetroot juice improves endothelial function but not tissue oxygenation in pregnant women: a randomised clinical trial

British Journal Of Nutrition ◽

10.1017/s0007114518002441 ◽

2018 ◽

Vol 120 (9) ◽

pp. 1006-1013 ◽

Cited By ~ 5

Author(s):

Mônica Volino-Souza ◽

Gustavo Vieira de Oliveira ◽

Thiago Silveira Alvares

Keyword(s):

Single Dose ◽

Endothelial Function ◽

Pregnant Women ◽

Cardiovascular Health ◽

Randomised Clinical Trial ◽

Beetroot Juice ◽

Double Blind ◽

Muscle Oxygen ◽

Significant Difference ◽

Double Blind Design

AbstractBeetroot juice (BJ) consumption has been associated with improved cardiovascular health owing to an increase in NO bioconversion. This study evaluates the effect of BJ consumption on macrovascular endothelial function (flow-mediated dilation (FMD)) and muscle oxygen saturation (StO2) parameters in pregnant women within a randomised, crossover, double-blind design in which twelve pregnant women consumed a single dose (140 ml) of BJ or placebo (PLA). Urinary nitrate was assessed before (T0) and 150 min after BJ/PLA consumption. FMD was used to evaluate macrovascular endothelial function, and near-IR spectroscopy was used to evaluate muscle StO2 parameters during the occlusion and reperfusion phases, which were taken at baseline (PRE) and 120 and 140 min after BJ/PLA consumption, respectively. A significant increase in urinary nitrate was observed at 150 min after BJ consumption when compared with T0 (BJ: 0·20 (sd 0·13) v. T0: 0·02 (sd 0·00), P=0·000) and PLA intervention (PLA: 0·02 (sd 0·00), P=0·001). FMD improved after BJ consumption when compared with PRE (BJ: 11·00 (sd 1·67) v. PRE: 5·53 (sd 1·17), P=0·000) and PLA (5·34 (sd 1·31), P=0·000). No significant difference between PLA and PRE in FMD (P=1·000) was observed. In StO2 parameters, a difference was not observed after BJ consumption compared with PRE and PLA intervention. The data demonstrate that a single dose of 140 ml of BJ consumption improves macrovascular endothelial function, but not StO2 parameters.

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Primary Dysmenorrhea Intensity Between Stretching Abdominal Therapy and Acupuncture to Adolescent Girls

10.31219/osf.io/f26t5 ◽

2021 ◽

Author(s):

Ni Nyoman Suindri ◽

Ni Luh Putu Sri Erawati ◽

Made Widhi Gunapria Darmapatni ◽

Ni Gusti Kompiang Sriasih

Keyword(s):

High School ◽

High School Students ◽

Adolescent Girls ◽

Rating Scales ◽

Wilcoxon Test ◽

P Value ◽

Menstrual Pain ◽

Significant Difference ◽

Before And After ◽

The Difference

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Game Model Based on Environment Insights for Elementary School Children (6-12 Years)

Budapest International Research and Critics in Linguistics and Education (BirLE) Journal ◽

10.33258/birle.v3i1.845 ◽

2020 ◽

Vol 3 (1) ◽

pp. 500-506

Author(s):

Marlinda Budiningsih ◽

Nofi Marlina Siregar ◽

Hernawan Hernawan

Keyword(s):

Elementary School ◽

School Children ◽

Elementary School Children ◽

Product Evaluation ◽

P Value ◽

Game Model ◽

Model Based ◽

Significant Difference ◽

Before And After ◽

The Difference

This study aims to create a product in the form of a game model based on environmental insights for elementary school children. This research is a research development using research and development from Borg and Gall which consists of ten steps. In this study, researchers only used eight steps because after conducting a small group trial and product evaluation it was declared to be feasible for a primary trial or field trial by experts. This study involved 80 subjects aged 6-12 years. Data collected through observation, interviews, and tests.The significant value of the difference in the results of t-count = 28,971, and p-value = 0.00 <0.05, which means there is a significant difference in understanding of environmental insights before and after being treated in the form of a game model based on environmental insights. It was concluded that the game model developed was effective in increasing understanding of environmental knowledge for children aged 6-12 years.

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The Differences of Myelosuppression before and after Doxorubicin Chemotherapy in Breast Cancer Patients in Rsup. H. Adam Malik Medan

International Journal of Research and Review ◽

10.52403/ijrr.20210704 ◽

2021 ◽

Vol 8 (7) ◽

pp. 18-24

Author(s):

Arnaldi Fernando ◽

Dairion Gatot ◽

Yan Indra Fajar Sitepu

Keyword(s):

Breast Cancer ◽

Cancer Patients ◽

Therapeutic Option ◽

P Value ◽

Breast Cancer Patients ◽

Research Subjects ◽

Mortality And Morbidity ◽

Significant Difference ◽

Before And After ◽

The Difference

Introduction: Breast cancer is formed from breast cells, either lobule or duct epithelium, which undergoes uncontrolled growth and development. The therapy of breast cancer to reduce mortality and morbidity can be done by way of surgery, chemotherapy, and radiotherapy. Doxorubicin chemotherapy is a therapeutic option to kill cells directly or by stopping the cell division based on the tumor pathogenesis. Method: This research is a paired numerical comparative analytical study using a retrospective cohort approach. This study was conducted on 56 breast cancer patients to see the differences in myelosuppression before and after doxorubicin chemotherapy at H. Adam Malik General Hospital Medan from January-December 2019. The data were obtained through recording the routine blood laboratory results listed in the patient's medical record and were analyzed with dependent t-test by using SPSS. The difference is significant if p <0.05. Result: The results showed that the average age of the research subjects was 40.79 years, 28 patients (50%) graduated from high school, 38 patients (67.9%) did not work and 53 patients (94.6%) had marital status. In a significant myelosuppression difference, anemia occured with chemotherapy Hb levels of 8.48 ± 1.09, the Hb difference in Hb prior to and after doxorubicin chemotherapy obtained a mean of 1.28 with p value <0.001. Conclusion: Based on the demographic characteristics of patients with breast cancer, it was found that the mean age of patients with breast cancer in women was 46.79 years; most of the subject’s education level was highschool, unemployed and married status. There was a very significant difference between the subject's Hb level and breast cancer before and after doxorubicin chemotherapy. Keywords: myelosuppression, doxorubicin, breast cancer.

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EDUKASI PRENATAL ATTACHMENT DAPAT MENINGKATKAN KELEKATAN IBU DAN JANIN PADA IBU HAMIL RISIKO TINGGI

Jurnal Ilmiah Perawat Manado (Juiperdo) ◽

10.47718/jpd.v8i01.1023 ◽

2020 ◽

Vol 8 (01) ◽

pp. 34-51

Author(s):

Mariani Mariani ◽

Shinta Wahyusari ◽

Nova Hikmawati

Keyword(s):

High Risk ◽

Pregnant Women ◽

Sampling Technique ◽

First Trimester ◽

Average Score ◽

P Value ◽

Prenatal Attachment ◽

Significant Difference ◽

Before And After ◽

The Relationship

Introduction: The prevalence of high-risk pregnancies in Indonesia is still quite high. Mothers who suffer from illness and pregnancy complications can influence the outcome of the pregnancy, which risks the occurrence of maternal and fetal morbidity and mortality. The psychological effects of high-risk pregnancies are anxiety, stress, and the mother experiences a crisis that can affect the relationship between mother and fetus. These conditions can continue in the relationship between mother and baby after birth. Therefore there needs to be an effort to increase the attachment of the mother and fetus, one of which can be done by providing education. This study aims to determine the effect of prenatal attachment education on maternal and fetal attachment in high-risk pregnant women in Paiton Subdistrict, Probolinggo Regency. Method: The study was conducted in Paiton Subdistrict, Probolinggo Regency in Mei-Juni 2019. The research method used was quasy experiment using pre-post test design. The population in this study were all high risk pregnant women in Dringu Subdistrict, Probolinggo Regency. The sampling technique used in this study was purposive sampling by determining the sample in accordance with the inclusion criteria. The number of samples to be used was 20 respondents. Data collection techniques using a questionnaire. Data were analyzed using Wilcoxon using SPSS. Results and Analysis: The results obtained showed the average score of attachment of the mother and fetus before the intervention was 52.15 and after the intervention was 60.50. There was a significant difference in the attachment of the mother and fetus before and after the intervention with a p value of 0,000 (p <0,000). Discussion: Prenatal care education needs to be included in the prenatal classroom program and started being given to pregnant women since the first trimester. Keywords: attachment, prenatal attachment, high risk pregnant women

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Efektivitas Ekstrak Daun Kelor ( Moringa Oleifera) terhadap Penurunan Kadar Kolesterol Total pada Tikus Putih ( Rattus Novergicus)

Green Medical Journal ◽

10.33096/gmj.v1i1.24 ◽

2019 ◽

Vol 1 (1) ◽

pp. 97-110

Author(s):

Sri Wahyu ◽

Andi Sitti Fahirah Arsal ◽

Indah Chintya Maharani

Keyword(s):

Cholesterol Level ◽

Leaf Extract ◽

Moringa Oleifera ◽

Blood Cholesterol ◽

P Value ◽

Test Results ◽

Cholesterol Levels ◽

Before And After ◽

The Mean ◽

Moringa Leaf Extract

Introduction: The prevalence of hypercholesterolemia in Indonesia is estimated to increased continously. One of the traditional medicines used to reduce blood cholesterol levels is Moringa oleifera Lam, After using the extract of Moringa leaves, the cholesterol levels slowly reduced, it because by the active substance component on Moringa leaves such as flavanoid, tannin saponin and β-sitosterol. Objective : To determine the effect of Moringa leaf extract on reduce total cholesterol levels. Methods : The research is an analytical research, using pre-experimental design with one group pre-test method post-test approach. By comparing treatment groups and control groups where the treatment group was treated on the form of Moringa leaf extract. Results: The Paired T test showed that in the treatment group using Moringa leaf extract obtained before intervention the average cholesterol level was 307.40 mg/dl and after the interval was 209.00 mg/dl. Statistical test results obtained p value (0.00041) <0.05 which means that there is a difference of the mean cholesterol level between before and after treatment. Besides, the group using simvastatin was obtained before the intervention of the average cholesterol level was 271.20 mg/dl and after the interval was 127.40 mg/dl. Statistical test results obtained p value (0.009) <0.05 which means that there is a difference of the mean cholesterol level between before and after treatment. Conclusion: There wasn’t any significant differences between the Moringa leaves and simvastatin use to reduce the total blood cholesterol levels.

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Impact of educational preeclampsia prevention booklet on knowledge and adherence to low dose aspirin among pregnant women with high risk for preeclampsia

Journal of Basic and Clinical Physiology and Pharmacology ◽

10.1515/jbcpp-2019-0299 ◽

2020 ◽

Vol 30 (6) ◽

Author(s):

Rella Indah Karunia ◽

Anita Purnamayanti ◽

Fransiscus O.H. Prasetyadi

Keyword(s):

High Risk ◽

Pregnant Women ◽

Low Dose ◽

P Value ◽

Dose Aspirin ◽

Validated Questionnaire ◽

Low Dose Aspirin ◽

Significant Difference ◽

Before And After ◽

The Impact

AbstractBackgroundPostpartum bleeding and pregnancy induced hypertension – including preeclampsia – remain to be a great cause of maternal mortality. The use of aspirin for preventing preeclampsia has been practiced recently by fetomaternal specialists in Indonesia. This study aimed to analyze the impact of education using an aspirin booklet provided by pharmacists on knowledge and adherence in taking aspirin among pregnant women with high risk for preeclampsia.MethodsThis was one group of pretest-posttest study. We enrolled all pregnant women with high risk for preeclampsia screened at 11+0–13+6 weeks’ gestation at Fetomaternal Clinic, Dr. Ramelan Naval Hospital, Surabaya. All subjects prescribed with low-dose aspirin (100 mg) for preeclampsia prevention received oral and written education using the aspirin booklet and had been followed up for 2 months. Knowledge about aspirin for preeclampsia prevention was measured by a validated questionnaire developed for this study. Adherence to aspirin was measured by pill count method.ResultsA total of 12 pregnant women with high risk for preeclampsia were included during the study period. This study showed a statistically significant difference on knowledge of preeclampsia prevention before and after receiving oral and written education using aspirin booklet (p-value = 0.020), as well as aspirin adherence (p-value = 0.011).ConclusionThe use of oral education and written aspirin booklet provided by pharmacists had impact on knowledge of preeclampsia prevention and adherence in taking aspirin among pregnant women with high risk for preeclampsia. We recommend to conduct randomized control study of adequate number of subjects.

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