scholarly journals PO-176 The Effects of Different Intensity Treadmill Exercise to Kidney Functions

2018 ◽  
Vol 1 (4) ◽  
Author(s):  
Ling Yang ◽  
Wen Tao Lin ◽  
Xi Quan Weng

Objective  To provide more scientific and authoritative theoretical basis for body-building exercises after analyzing the changes of exercises of different intensities for the kidney functions. Methods  The objects of the research are eight male students from Guangzhou Sport College, being exerted the treadmill exercises according to their own maximum oxygen intake. The intensities of exercises are respectively 55%VO2max, 75%VO2max, 85%VO2max, 95%VO2max. The urine 40ml and venous blood 3ml will be collected and tested before sport and 15minutes after the exercises. Results  After four different intensities of exercise, the renin of each exercise group increased compared with the quiet value, and the greater the intensity, the more obvious the trend of change. Compared with the quiet value, the expression of angiotensin II increased in all groups after exercise, but there was no significant difference between the 55%VO2max intensity group and the 75%VO2max intensity group (P > 0.05), and there was significant difference between the 85%VO2max intensity group and the 95%VO2max intensity group (P < 0.05). Compared with the quiet value, the expression of aldosterone increased after each exercise. The mean value of 55%VO2max intensity group, 75%VO2max intensity group and 85%VO2max intensity group increased, but the difference was not significant (P > 0.05), and the 95%VO2max intensity group had a very significant difference (P < 0.01). The expression of urine beta 2 microglobulin was compared with the quiet value. There was significant difference in 85%VO2max intensity group and 95%VO2max intensity group (P<0.05). Conclusions High-intensity exercise causes renal function and body function decline. It is more appropriate to select 75% intensity exercise for body-building.

2018 ◽  
Vol 1 (2) ◽  
pp. 114
Author(s):  
Wahdaniah Wahdaniah ◽  
Sri Tumpuk

Abstract: Routine blood examination is the earliest blood test or screening test to determine the diagnosis of an abnormality. Blood easily froze if it is outside the body and can be prevented by the addition of anticoagulants, one of which Ethylene Diamine Tetra Acetate (EDTA). Currently available vacuum tubes containing EDTA anticoagulants in the form of K2EDTA and K3EDTA. K3EDTA is usually a salt that has better stability than other EDTA salts because it shows a pH approaching a blood pH of about 6.4. The purpose of this research is to know the difference of erythrocyte index results include MCH, MCV and MCHC using K3EDTA anticoagulant with K2EDTA. This research is a cross sectional design. This study used venous blood samples mixed with K2EDTA anticoagulant and venous blood mixed with K3EDTA anticoagulants, each of 30 samples. Data were collected and analyzed using paired different test. Based on data analysis that has been done on MCH examination, p value <0,05 then there is a significant difference between samples with K3EDTA anticoagulant with K2EDTA to erythrocyte index value. Then on the examination of MCV and MCHC obtained p value <0.05 then there is no significant difference between samples with K3EDTA anticoagulant with K2EDTA to erythrocyte index value.Abstrak: Pemeriksaan darah rutin merupakan pemeriksaan darah yang paling awal atau screening test untuk mengetahui diagnosis suatu kelainan. Darah mudah membeku jika berada diluar tubuh dan bisa dicegah dengan penambahan antikoagulan, salah satunya Ethylene Diamine Tetra Acetate (EDTA). Dewasa ini telah tersedia tabung vakum yang sudah berisi antikoagulan EDTA dalam bentuk  K2EDTA dan  K3EDTA. K3EDTA  biasanya berupa garam yang mempunyai stabilitas yang lebih baik dari garam EDTA yang lain karena menunjukkan pH yang mendekati pH darah yaitu sekitar 6,4. Tujuan dari penelitian ini adalah untuk mengetahui perbedaan hasil indeks eritrosit meliputi MCH, MCV dan MCHC menggunakan antikoagulan K3EDTA dengan K2EDTA. Penelitian ini merupakan penelitian dengan desain cross sectional. Penelitian ini menggunakan sampel darah vena yang dicampur dengan antikoagulan K2EDTA dan darah vena yang dicampur dengan antikoagulan K3EDTA, masing-masing sebanyak 30 sampel. Data dikumpulkan dan dianalisis menggunakan uji beda berpasangan. Berdasarkan analisis data yang telah dilakukan pada pemeriksaan MCH didapatkan nilai p < 0,05 maka ada perbedaan yang signifikan antara sampel dengan antikoagulan K3EDTA dengan K2EDTA terhadap nilai indeks eritrosit. Kemudian pada pemeriksaan MCV dan MCHC didapatkan nilai p < 0,05 maka tidak ada perbedaan yang signifikan antara sampel dengan antikoagulan K3EDTA dengan K2EDTA terhadap nilai indeks eritrosit.


2012 ◽  
Vol 2012 ◽  
pp. 1-6
Author(s):  
Thomas Nubila ◽  
Ernest O. Ukaejiofo ◽  
Nkoyo I. Nubila ◽  
Godfrey I. Okorie

Highly active antiretroviral therapy (HAART) is considered toxic and has other life-threatening side effects. Our aim was to evaluate the haematotoxic effects of lamivudine, zidovudine, and nevirapine fixed-dose combinations in Albino Wistar rats. Fifty (50) three (3) months old male Albino Wistar rats weighing between 200 and 250 g were randomly assigned to five (5) groups (A, B, C, D, and E). Group A served as control. Two (2 mLs) of venous blood was aseptically collected on Days 5, 10, 15, 20, and 25 of treatment. Red blood cell (RBC) mean value recorded statistically significant increase () in groups B and C when compared with the control group on Day 5. However, there was a statistically significant decrease () in RBC, haemoglobin concentration (Hb), packed cell volume (PCV), and some red cell indices on Day 10. In addition there was no statistically significant difference () in all the parameters evaluated when the test group was compared with the control on Day 25. Furthermore, there was a time-related statistically significant increase () in the two major blood cells—RBC and platelet counts. From the result of this present study, it can be concluded that HAART when administered in fixed-dose combinations have no subacute haematotoxic effects.


2017 ◽  
Vol 4 (2) ◽  
pp. 457
Author(s):  
Sujatha G. ◽  
Vindhya P. ◽  
Kalyan Kumar K.

Background: Approximately one million patients develop pleural effusion every year. It is a common clinical disorder and is either a manifestation or a complication of one or other respiratory or non-respiratory disorders. It leads to serious prognosis, if not diagnosed and treated properly. To calculate SEAG and Light’s criteria and to compare SEAG with Light’s criteria in analyzing pleural effusions.Methods: A total of hundred patients were selected for the study. Pleural fluid of patients who met the inclusion and exclusion criteria were collected, when pleural fluid is being tapped for diagnostic thoracocentesis. Venous blood sample was collected along with diagnostic thoracocentesis or within 24 hours of thoracocentesis.  Written informed consent was obtained from them for thoracocentesis.Results: In our study we compared the clinical outcome with outcome as per Pleural fluid/Serum protein ratio (p value of <0.0001), pleural fluid/serum LDH (p value of <0.0001) and pleural fluid LDH (p value of <0.0001) separately and the p values were statistically significant. The sensitivity, specificity, PPV and NPV of Light’s criteria were 77.2%, 100%, 100%, 93.9% respectively. We compared Light’s criteria outcome with clinical outcome and the difference was statistically significant (p value of <0.0001). SEAG showed 100% sensitivity, 97.43% specificity, 91.6% PPV and is 91.66% and NPV is 100%. We compared the clinical outcome with SEAG and there was statistically significant difference (p value of <0.0001). We compared SEAG with Light’s criteria and the difference was statistically significant (p <0.0001). We compared Light’s plus pleural fluid protein gradient with SEAG and the difference is statistically significant (p value of <0.0001).Conclusions: SEAG is more sensitive for classifying transudates and more specific for exudates than Light’s criteria.


2021 ◽  
Vol 12 (03) ◽  
pp. 39-44
Author(s):  
Anik Maryani ◽  
Fahmy Fachrezzy ◽  
Ramdan Pelana

This study aims to determine the effectiveness of the effect of aerobic mix impact and SKJ 2000 version (core exercise) to improve physical fitness in female students. The research was conducted at SMEA YASMA Sudirman Cijantung for 8 weeks with 24 meetings. The method used is an experimental method with a pre and post-test design. The sampling technique was random sampling from a total of 40 grade 1 students and 30 samples were taken. The data collection technique used was a physical fitness test using the Indonesian Physical Fitness Test (TKJI). Hypothesis testing uses the t-test at the significant level (α) 0.05. The results showed that the difference between the mean value of the initial test (x) and the final test (y) in the mixed impact aerobic exercise group was obtained = -6.47; the value of the standard deviation of the difference = 1,2; the standard error value of the mean difference = 0.32; and the value becomes = -20,2. The initial test (x) and the final test (y) in the 2000 version of the Physical Fitness exercise obtained the difference in the mean value is = -5; the value of the standard deviation of the difference = 1.1; the standard error value of the mean difference = 0.29; and the value becomes = -17.24. The final test of the mixed impact aerobic exercise group (x) and the final test of the aerobic exercise group (y) version 2000, obtained the mean value of the variable x = 19.33; variable value y = 17; the standard deviation value x = 1.48; standard deviation of the variable y = 2.31; standard error variable x = 0.4; standard error for the variable y = 0.62; standard error for the mean difference between x and variable = 0.74; Hypothesis test results obtained t observation = 3.15, at 28 degrees of freedom and a significant level (α) 0.05, the value of t table = 2.048 is obtained. The conclusion of the study is that the effect of mix impact aerobic exercise is more effective in improving physical fitness compared to those using the 2000 version of the fitness gymnastics version of aerobic exercise.


2021 ◽  
Vol 6 (1) ◽  
pp. 150-157
Author(s):  
Andi Amry Yahya ◽  
Sarifuddin Arham

This study was conducted to determine the effect of the learning method (TGT) and conventional learning methods on the learning outcomes of passing under volleyball in SMA Negeri 2 Bone students. This research method is a type of experimental research selected by random sampling then given a pretest and posttest with a population of all students of SMA Negeri 2 Bone. Furthermore, 2 (two) classes that have been randomly selected are then given treatment in the form of physical education learning in the form of the TGT cooperative learning model and the other one is not given treatment or carries out conventional learning. The data analysis technique used t test with a significant level of 0.05. The result of the unpaired t-test calculation shows that the t value is 5.069 and the probability value is 0.000 which is smaller than the α 0.05, which means that there is a significant difference in the effect between cooperative learning type TGT and conventional learning on improving the ability to pass under volleyball (p <0.05). The difference seen from the mean value of the final passing under test in the cooperative learning class TGT is 10.14 greater than the average value of the conventional class final test of 7.94. Thus it can be said that the TGT type of cooperative learning is better than conventional learning in improving the ability to pass under volleyball in SMA Negeri 2 Bone students.Keywords: TGT, under-passing, volleyball, student learning outcomes.AbstrakPenelitian ini dilakukan untuk mengetahui pengaruh antara metode pembelajaran (TGT) dan metode pembelajaran konvensional terhadap hasil belajar passing bawah permainan bola voli siswa SMA Negeri 2 Bone. Metode penelitian ini merupakan jenis penelitian eksperimen yang dipilih secara random sampling kemudian diberi pretest dan posttest dengan populasi seluruh siswa SMA Negeri 2 Bone. Selanjutnya 2 (dua) kelas yang telah dipilih secara acak kemudian diberikan perlakuan berupa pembelajaran pendidikan jasmani dalam bentuk model pembelajaran kooperatif tipe TGT dan yang satunya tidak diberi perlakuan atau melakukan pembelajaran secara konvensional. teknik analisis data yang digunakan uji t dengan taraf signifikan 0.05. Hasil perhitungan uji-t tidak berpasangan menunjukkan nilai t yaitu 5,069 dan nilai probabilitas yaitu 0,000 lebih kecil dari nilai α 0.05 berarti ada perbedaan pengaruh yang signifikan antara pembelajaran kooperatif tipe TGT dan pembelajaran konvensional terhadap peningkatan kemampuan passing bawah bolavoli (p < 0.05). Perbedaan dilihat dari nilai rata-rata tes akhir passing bawah kelas pembelajaran kooperatif tipe TGT sebesar 10,14 lebih besar dari nilai rata-rata tes akhir kelas konvensional sebesar 7,94. Dengan demikian dapat dikatakan bahwa pembelajaran kooperatif tipe TGT lebih baik dibandingkan pembelajaran konvensional dalam meningkatkan kemampuan passing bawah bola voli pada siswa SMA Negeri 2 Bone.Kata kunci: TGT, passing bawah, bolavoli, hasil belajar siswa. 


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Yuanyuan Zheng ◽  
Cui Ma ◽  
Xiaowei Liu ◽  
Shaowen Wu ◽  
Weiyuan Zhang ◽  
...  

Abstract Background Preeclampsia is an idiopathic disease during pregnancy. This study explores the correlation between HLA-A polymorphism and the onset of preeclampsia. Methods The Illumina HiSeq2500 sequencing platform was used to genotyping HLA-A allele in venous blood DNA of 50 preeclampsia pregnant women and 48 normal pregnant women and umbilical cord blood DNA of their children of Han nationality in China. The frequencies and distributions of alleles and genotypes among the mothers and their children were compared between the two groups. The differences of frequencies and distributions of genotypes were compared between the two groups according to the mothers’ genotype compatibility. Results Twenty HLA-A alleles were detected in preeclampsia pregnant women and normal pregnant women; 21 HLA-A alleles were found in preeclampsia group fetuses and 22 HLA-A alleles in control group fetuses. There was no statistical difference in the HLA-A genes’ frequency between the two groups of pregnant women and their fetuses. When the sharing antigen was 1, the number of maternal-fetal pairs in the preeclampsia group was more than that in the control group; the difference was statistically significant (P < 0.05). The frequency of neither mother nor fetus carrying the HLA-A * 24: 02 gene in the preeclampsia group was significantly lower than that in the control group (P < 0.05). HLA-A gene homozygosity in fetuses of early-onset preeclampsia group was substantially higher than that of the control group (P = 0.0148); there is no significant difference in pregnant women’s genes homozygosity between early-onset preeclampsia group and the control group. Conclusions HLA-A * 24: 02 may be a susceptibility gene for early preeclampsia.


2018 ◽  
Vol 23 (2) ◽  
pp. 68-74 ◽  
Author(s):  
Sergio Luiz Mota Júnior ◽  
Marcio José da Silva Campos ◽  
Carina Abrantes Schmitberger ◽  
Juliana de Andrade Vitral ◽  
Marcelo Reis Fraga ◽  
...  

ABSTRACT Objective: The purposes of this study were to present a prototype of a bracket-positioning gauge, which makes vertical inclination of the instrument difficult, allowing a reduction of vertical bracket positioning error, and to test its accuracy in bracket positioning by groups of individuals with different clinical experience and in specific groups of teeth. Methods: For the testing of the prototype, four groups of six participants each were used: Group 1 was composed of undergraduate students in the dental school, who had no previous experience in bonding orthodontic attachments; Group 2 was composed of orthodontic graduate students in the dental school; Group 3 consisted of orthodontists with a maximum of 5 years of clinical experience; Group 4 comprised orthodontists with more than 5 years of clinical experience. A typodont was simulated with a Class I crowded malocclusion, which reproduced the same occlusal characteristics for all groups to be bonded. All participants were instructed to bond 0.022×0.028-in Edgewise brackets on the labial surfaces of the upper and lower incisors, canines, and premolars at a height of 4 mm from the incisal edge or the labial cusp tip. Results: Only the mean value of Group 1 showed statistically significant difference in the comparison with the standard measurement. In the groups of teeth, the difference was significant for the premolar and incisor groups. Conclusion: Clinical experience interfered with the accuracy of vertical positioning of orthodontic attachments. As for the groups of teeth, premolars, followed by canines and incisors had the closest mean values to the standard measurement.


Author(s):  
Suyanto Suyanto ◽  
Venia Evika Al Islami

Background: Airway obstruction in COPD patients results in decreased oxygen saturation (SPO2) values. COPD non-pharmacological therapy with pursed lip breathing and 6 minutes walk exercise can theoretically increase the functional capacity of the lungs and have an impact on the value of oxygen saturation in the blood of unknown difference. Therefore the study aims to determine the difference in oxygen saturation values ​​between pursed lip breathing and 6 minutes walk exercise in COPD patients at the Central Pulmonary Health Center (BBKPM) Surakarta. Method: This research is a quasi-experimental study using two groups of pre and post test design. COPD patients treated at BBKPM Surakarta became the study population whose samples were taken by purposive sampling technique of 60 respondents. Data were analyzed using the Shapiro-Wilk normality test and then performed a parametric statistical test using the Mann Whitney test Results: The results showed that the average SPO2 value of pre and post in the pursed lip breathing intervention group increased 2.69%, while for the intervention group 6 minutes walk exercise increased an average of 1.71%. There is a significant difference in the average SPO2 value between pursed lip breathing and 6 minutes walk exercise which results sig (2-tailed) 0,000. Conclusion: The average SPO2 value of the pursed lip breathing intervention group was higher than the 6 minutes walk exercise group and it was proven that the difference was significant


2021 ◽  
Vol 7 (1) ◽  
pp. 16-18
Author(s):  
Yuni Selfiana Br. Sembiring ◽  
Rudyn Reymond Panjaitan ◽  
Kristo A Nababan

Background: Acne vulgaris is a disease of the pilosebaceous unit that often occurs in adolescents and young adults. The pathogenesis of acne vulgaris involves several factors, one of which is the acidity (pH) of the skin.  Objective: This study aimed to determine the difference in the degree of acidity of facial skin, chest and back of patients with acne vulgaris.  Methods: This was a comparative analytic study with cross sectional design. The sample collection technique was consecutive sampling. Data were analyzed using ANOVA-test.  Results: The majority of patients with acne vulgaris who came to Murni Teguh Memorial Hospital Medan and the private clinic of dr. Rudyn Reymond Panjaitan, M.Ked (KK), Sp.KK was a 17-25 year old. The mean acidity of facial skin with acne vulgaris was 5.66, the mean acidity of chest skin was 5,84 and the mean acidity of back skin was 6.09. There was a significant difference in the mean value of acidity in facial, chest and back skin of patients with acne vulgaris (p = 0,000). Conclusion: There is a significant difference in average degree of acidity on the facial, chest and back skin in patients with acne vulgaris.


2018 ◽  
Vol 2 (2) ◽  
Author(s):  
Pradipta Pradipta Kurniasanti ◽  
M Zen Rahfiludin ◽  
Sri Winarni

Abstract: Good quality velvet beans and zinc supplement are well studied and known as rich source ofaphrodisiac. The following reseach was carried out to study the difference effect of zinc supplement (ZS)and velvet bean extracts (VBE) towards fertility of BALB/c mice i.e the number of sperm, the motility ofsperm, the viability of sperm, the morphology of sperm, the existence of vagina plug, and the birthcondition of mice. This study was an experiment using Posttest Only Controlled Group Design with threegroups. The first group (A1) as control, the second group (A2) receives subcutaneous injection of 2-methoxyethanol fraction as much as 200 mg/kg weight/day for 5 days, followed with ZS at a dosage of0,026 mg/day/head, and the third group (A3) receives subcutaneous injection of 2-methoxyethanolfraction as much as 200 mg/kg weight/day for 5 days, followed with VBE at a dosage of 56 mg/kg weight/day for 30 days. The quality of spermatozoa of A1, A2, and A3 was significant difference (p < 0.05).Both of A2 and A3 were no significant difference of mean number of sperm (p = 0.274), mean percentageof sperm motility (p = 0.739), mean percentage of sperm viability (p = 0.141) and mean value ofmorphology of sperm (p = 0.394). The quality of spermatozoa and the total number of baby mice livedand died of A1, A2 and A3 were significant difference. In addition, there was no significant differencein the existence of female mice's vaginal plug of A1, A2 and A3. This study showed that ZS and VBE canincrease the quality of spermatozoa of BALB/C mice.


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