scholarly journals Prediction of Diabetes with Deep Neural Network

Webology ◽  
2021 ◽  
Vol 18 (2) ◽  
pp. 806-814
Author(s):  
Yaser Issam Hamodi
Keyword(s):  
Prediction Model ◽  
Deep Neural Network ◽  
Deep Neural Networks ◽  
Cross Validation ◽  
Health Issues ◽  
Diabetic Mellitus ◽  
Eye Problems ◽  
Deadly Disease ◽  
Prediction Of Diabetes ◽  
Fold Cross Validation

Diabetic mellitus is hitting the globe since decades. it often leads to dangerous health issues such as kidney problems, heart strokes, nervous system disturbance and eye problems etc. The prediction and detection of such a deadly disease is pivotal. In the conducted study, we have built a diabetic prediction model which is based on deep neural networks. We performed our experiments with two-fold and four-fold cross validation. Our diabetic prediction model has reported an accuracy of 98.45% which is quite high.

scholarly journals PredAmyl-MLP: Prediction of Amyloid Proteins Using Multilayer Perceptron

2020 ◽  
Vol 2020 ◽  
pp. 1-12
Author(s):  
Yanjuan Li ◽  
Zitong Zhang ◽  
Zhixia Teng ◽  
Xiaoyan Liu
Keyword(s):  
Feature Extraction ◽  
Feature Selection ◽  
Prediction Model ◽  
Multilayer Perceptron ◽  
Type Ii Diabetes ◽  
Cross Validation ◽  
Experimental Results ◽  
Type Ii ◽  
Fold Cross Validation ◽  
Better Than

Amyloid is generally an aggregate of insoluble fibrin; its abnormal deposition is the pathogenic mechanism of various diseases, such as Alzheimer’s disease and type II diabetes. Therefore, accurately identifying amyloid is necessary to understand its role in pathology. We proposed a machine learning-based prediction model called PredAmyl-MLP, which consists of the following three steps: feature extraction, feature selection, and classification. In the step of feature extraction, seven feature extraction algorithms and different combinations of them are investigated, and the combination of SVMProt-188D and tripeptide composition (TPC) is selected according to the experimental results. In the step of feature selection, maximum relevant maximum distance (MRMD) and binomial distribution (BD) are, respectively, used to remove the redundant or noise features, and the appropriate features are selected according to the experimental results. In the step of classification, we employed multilayer perceptron (MLP) to train the prediction model. The 10-fold cross-validation results show that the overall accuracy of PredAmyl-MLP reached 91.59%, and the performance was better than the existing methods.

scholarly journals Hybrid Support Vector Regression Model and K-Fold Cross Validation for Water Quality Index Prediction in Langat River, Malaysia

2021 ◽  
Author(s):  
Naeimah Mamat ◽  
Firdaus Mohamad Hamzah ◽  
Othman Jaafar
Keyword(s):  
Water Quality ◽  
Prediction Model ◽  
Support Vector Regression ◽  
Water Quality Index ◽  
Quality Index ◽  
Cross Validation ◽  
Oxygen Demand ◽  
Support Vector ◽  
Langat River ◽  
Fold Cross Validation

AbstractWater quality analysis is an important step in water resources management and needs to be managed efficiently to control any pollution that may affect the ecosystem and to ensure the environmental standards are being met. The development of water quality prediction model is an important step towards better water quality management of rivers. The objective of this work is to utilize a hybrid of Support Vector Regression (SVR) modelling and K-fold cross-validation as a tool for WQI prediction. According to Department of Environment (DOE) Malaysia, a standard Water Quality Index (WQI) is a function of six water quality parameters, namely Ammoniacal Nitrogen (AN), Biochemical Oxygen Demand (BOD), Chemical Oxygen Demand (COD), Dissolved Oxygen (DO), pH, and Suspended Solids (SS). In this research, Support Vector Regression (SVR) model is combined with K-fold Cross Validation (CV) method to predict WQI in Langat River, Kajang. Two monitoring stations i.e., L15 and L04 have been monitored monthly for ten years as a case study. A series of results were produced to select the final model namely Kernel Function performance, Hyperparameter Kernel value, K-fold CV value and sets of prediction model value, considering all of them undergone training and testing phases. It is found that SVR model i.e., Nu-RBF combined with K-fold CV i.e., 5-fold has successfully predicted WQI with efficient cost and timely manner. As a conclusion, SVR model and K-fold CV method are very powerful tools in statistical analysis and can be used not limited in water quality application only but in any engineering application.

scholarly journals EEG-Driven Prediction Model of Oxcarbazepine Treatment Outcomes in Patients With Newly-Diagnosed Focal Epilepsy

2022 ◽  
Vol 8 ◽  
Author(s):  
Bin Wang ◽  
Xiong Han ◽  
Zongya Zhao ◽  
Na Wang ◽  
Pan Zhao ◽  
...  
Keyword(s):  
Decision Tree ◽  
Prediction Model ◽  
Kolmogorov Complexity ◽  
Cross Validation ◽  
Prediction Models ◽  
Focal Epilepsy ◽  
Gradient Boosting ◽  
Newly Diagnosed ◽  
Sensitivity Specificity ◽  
Fold Cross Validation

Objective: Antiseizure medicine (ASM) is the first choice for patients with epilepsy. The choice of ASM is determined by the type of epilepsy or epileptic syndrome, which may not be suitable for certain patients. This initial choice of a particular drug affects the long-term prognosis of patients, so it is critical to select the appropriate ASMs based on the individual characteristics of a patient at the early stage of the disease. The purpose of this study is to develop a personalized prediction model to predict the probability of achieving seizure control in patients with focal epilepsy, which will help in providing a more precise initial medication to patients.Methods: Based on response to oxcarbazepine (OXC), enrolled patients were divided into two groups: seizure-free (52 patients), not seizure-free (NSF) (22 patients). We created models to predict patients' response to OXC monotherapy by combining Electroencephalogram (EEG) complexities and 15 clinical features. The prediction models were gradient boosting decision tree-Kolmogorov complexity (GBDT-KC) and gradient boosting decision tree-Lempel-Ziv complexity (GBDT-LZC). We also constructed two additional prediction models, support vector machine-Kolmogorov complexity (SVM-KC) and SVM-LZC, and these two models were compared with the GBDT models. The performance of the models was evaluated by calculating the accuracy, precision, recall, F1-score, sensitivity, specificity, and area under the curve (AUC) of these models.Results: The mean accuracy, precision, recall, F1-score, sensitivity, specificity, AUC of GBDT-LZC model after five-fold cross-validation were 81%, 84%, 91%, 87%, 91%, 64%, 81%, respectively. The average accuracy, precision, recall, F1-score, sensitivity, specificity, AUC of GBDT-KC model with five-fold cross-validation were 82%, 84%, 92%, 88%, 83%, 92%, 83%, respectively. We used the rank of absolute weights to separately calculate the features that have the most significant impact on the classification of the two models.Conclusion: (1) The GBDT-KC model has the potential to be used in the clinic to predict seizure-free with OXC monotherapy. (2). Electroencephalogram complexity, especially Kolmogorov complexity (KC) may be a potential biomarker in predicting the treatment efficacy of OXC in newly diagnosed patients with focal epilepsy.

scholarly journals A learning based framework for diverse biomolecule relationship prediction in molecular association network

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Zhen-Hao Guo ◽  
Zhu-Hong You ◽  
De-Shuang Huang ◽  
Hai-Cheng Yi ◽  
Zhan-Heng Chen ◽  
...  
Keyword(s):  
Random Forest ◽  
Prediction Model ◽  
Computational Models ◽  
Cross Validation ◽  
Random Forest Classifier ◽  
Regulatory Mechanisms ◽  
Association Network ◽  
Great Hope ◽  
Fold Cross Validation ◽  
Graph Factorization

AbstractAbundant life activities are maintained by various biomolecule relationships in human cells. However, many previous computational models only focus on isolated objects, without considering that cell is a complete entity with ample functions. Inspired by holism, we constructed a Molecular Associations Network (MAN) including 9 kinds of relationships among 5 types of biomolecules, and a prediction model called MAN-GF. More specifically, biomolecules can be represented as vectors by the algorithm called biomarker2vec which combines 2 kinds of information involved the attribute learned by k-mer, etc and the behavior learned by Graph Factorization (GF). Then, Random Forest classifier is applied for training, validation and test. MAN-GF obtained a substantial performance with AUC of 0.9647 and AUPR of 0.9521 under 5-fold Cross-validation. The results imply that MAN-GF with an overall perspective can act as ancillary for practice. Besides, it holds great hope to provide a new insight to elucidate the regulatory mechanisms.

A Quantitative Approach to Measure Webpage Aesthetics

2020 ◽  
Vol 16 (2) ◽  
pp. 53-68
Author(s):  
Ranjan Maity ◽  
Samit Bhattacharya
Keyword(s):  
Root Mean Square Error ◽  
Prediction Model ◽  
Computational Model ◽  
Support Vector Regression ◽  
Mean Square Error ◽  
Cross Validation ◽  
Support Vector ◽  
Mean Square ◽  
Validation Technique ◽  
Fold Cross Validation

Aesthetics measurement is important in determining and improving the usability of a webpage. Wireframe models, the collection of the rectangular objects, can approximate the size and positions of the different webpage elements. The positional geometry of these objects is primarily responsible for determining aesthetics as shown in studies. In this work, the authors propose a computational model for predicting webpage aesthetics based on the positional geometry features. In this study, the authors found that ten out of the thirteen reported features are statistically significant for webpage aesthetics. Using these ten features, the authors developed a computational model for webpage aesthetics prediction. The model works on the basis of support vector regression. The authors rated the wireframe models of 209 webpages by 150 participants. The average users' ratings and the ten significant features' values were used to train and test the aesthetics prediction model. Five-fold cross-validation technique shows the model can predict aesthetics with a Root Mean Square Error (RMSE) of only 0.42.

scholarly journals Himawari-8 Aerosol Optical Depth (AOD) Retrieval Using a Deep Neural Network Trained Using AERONET Observations

2020 ◽  
Vol 12 (24) ◽  
pp. 4125
Author(s):  
Lu She ◽  
Hankui K. Zhang ◽  
Zhengqiang Li ◽  
Gerrit de Leeuw ◽  
Bo Huang
Keyword(s):  
Neural Network ◽  
Random Forest ◽  
Aerosol Optical Depth ◽  
Optical Depth ◽  
Land Surface ◽  
Deep Neural Network ◽  
Cross Validation ◽  
Japan Meteorological Agency ◽  
Pixel Location ◽  
Fold Cross Validation

Spectral aerosol optical depth (AOD) estimation from satellite-measured top of atmosphere (TOA) reflectances is challenging because of the complicated TOA-AOD relationship and a nexus of land surface and atmospheric state variations. This task is usually undertaken using a physical model to provide a first estimate of the TOA reflectances which are then optimized by comparison with the satellite data. Recently developed deep neural network (DNN) models provide a powerful tool to represent the complicated relationship statistically. This study presents a methodology based on DNN to estimate AOD using Himawari-8 Advanced Himawari Imager (AHI) TOA observations. A year (2017) of AHI TOA observations over the Himawari-8 full disk collocated in space and time with Aerosol Robotic Network (AERONET) AOD data were used to derive a total of 14,154 training and validation samples. The TOA reflectance in all six AHI solar bands, three TOA reflectance ratios derived based on the dark-target assumptions, sun-sensor geometry, and auxiliary data are used as predictors to estimate AOD at 500 nm. The DNN AOD is validated by separating training and validation samples using random k-fold cross-validation and using AERONET site-specific leave-one-station-out validation, and is compared with a random forest regression estimator and Japan Meteorological Agency (JMA) AOD. The DNN AOD shows high accuracy: (1) RMSE = 0.094, R2 = 0.915 for k-fold cross-validation, and (2) RMSE = 0.172, R2 = 0.730 for leave-one-station-out validation. The k-fold cross-validation overestimates the DNN accuracy as the training and validation samples may come from the same AHI pixel location. The leave-one-station-out validation reflects the accuracy for large-area applications where there are no training samples for the pixel location to be estimated. The DNN AOD has better accuracy than the random forest AOD and JMA AOD. In addition, the contribution of the dark-target derived TOA ratio predictors is examined and confirmed, and the sensitivity to the DNN structure is discussed.

scholarly journals Assessment of dysplasia in bone marrow smear with convolutional neural network

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Jinichi Mori ◽  
Shizuo Kaji ◽  
Hiroki Kawai ◽  
Satoshi Kida ◽  
Masaharu Tsubokura ◽  
...  
Keyword(s):  
Neural Network ◽  
Bone Marrow ◽  
Predictive Value ◽  
Blood Cells ◽  
Deep Neural Network ◽  
Cross Validation ◽  
Natural Images ◽  
Point Scale ◽  
Sensitivity Specificity ◽  
Fold Cross Validation

Abstract In this study, we developed the world's first artificial intelligence (AI) system that assesses the dysplasia of blood cells on bone marrow smears and presents the result of AI prediction for one of the most representative dysplasia—decreased granules (DG). We photographed field images from the bone marrow smears from patients with myelodysplastic syndrome (MDS) or non-MDS diseases and cropped each cell using an originally developed cell detector. Two morphologists labelled each cell. The degree of dysplasia was evaluated on a four-point scale: 0–3 (e.g., neutrophil with severely decreased granules were labelled DG3). We then constructed the classifier from the dataset of labelled images. The detector and classifier were based on a deep neural network pre-trained with natural images. We obtained 1797 labelled images, and the morphologists determined 134 DGs (DG1: 46, DG2: 77, DG3: 11). Subsequently, we performed a five-fold cross-validation to evaluate the performance of the classifier. For DG1–3 labelled by morphologists, the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy were 91.0%, 97.7%, 76.3%, 99.3%, and 97.2%, respectively. When DG1 was excluded in the process, the sensitivity, specificity, PPV, NPV, and accuracy were 85.2%, 98.9%, 80.6%, and 99.2% and 98.2%, respectively.

scholarly journals iTAGPred: A Two-Level Prediction Model for Identification of Angiogenesis and Tumor Angiogenesis Biomarkers

2021 ◽  
Vol 2021 ◽  
pp. 1-15
Author(s):  
Khalid Allehaibi ◽  
Yaser Daanial Khan ◽  
Sher Afzal Khan
Keyword(s):  
Prediction Model ◽  
Tumor Angiogenesis ◽  
Cross Validation ◽  
Biological Process ◽  
Vital Role ◽  
Support Vector ◽  
Abnormal Growth ◽  
In Silico Identification ◽  
Self Consistency ◽  
Fold Cross Validation

A crucial biological process called angiogenesis plays a vital role in migration, growth, and wound healing of endothelial cells and other processes that are controlled by chemical signals. Angiogenesis is the process that controls the growth of blood vessels within tissues while angiogenesis proteins play a significant role in the proper working of this process. The balancing of these signals is necessary for the proper working of angiogenesis. Unbalancing of these signals increases blood vessel formation, which causes abnormal growth or several diseases including cancer. The proposed work focuses on developing a two-layered prediction model using different classifiers like random forest (RF), neural network, and support vector machine. The first level performs in silico identification of angiogenesis proteins based on the primary structure. In the case the protein is an angiogenesis protein, then the second level predicts whether the protein is linked with tumor angiogenesis or not. The performance of the model is evaluated through various validation techniques. The model was evaluated using k -fold cross-validation, independent, self-consistency, and jackknife testing. The overall accuracy using an RF classifier for angiogenesis at the first level was 97.8% and for tumor angiogenesis at the second level was 99.5%, ANN showed 94.1% accuracy for angiogenesis and 79.9% for tumor angiogenesis, and the accuracy of SVM for angiogenesis was 78.8% and for tumor angiogenesis was 65.19%.

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