scholarly journals Chromato-mass-spectroscopic research of chemical composition of Elaeagnus angustifolia L.

2021 ◽  
Vol 14 (2) ◽  
pp. 179-184
Author(s):  
O. I. Panasenko ◽  
V. I. Mozul ◽  
O. M. Denysenko ◽  
I. I. Aksonova ◽  
T. V. Oberemko
Keyword(s):  
Chemical Composition ◽  
Palmitic Acid ◽  
Isomeric State ◽  
Antioxidant Properties ◽  
Raw Material ◽  
Antidiabetic Activity ◽  
Elaeagnus Angustifolia ◽  
Mass Spectrometric Detector ◽  
Wide Range ◽  
Anti Inflammatory

The aim of the work was chromato-mass-spectroscopic research of chemical composition of Elaeagnus angustifolia L. fruits and leaves and identifying further prospects for the use of this plant in medicine. Materials and methods. Raw materials of Elaeagnus angustifolia L. were selected as objects of study. The tincture was obtained by maceration and the raw material was extracted with methyl alcohol at room temperature for 10 days according to the method of making tinctures. The study of the chemical composition of Elaeagnus angustifolia L. was carried out using gas chromatograph Agilent 7890B GC System (Agilent, Santa Clara, CA, USA) with mass spectrometric detector Agilent 5977 BGC/MSD (Agilent, Santa Clara, CA, USA) and chromatographic column DB-5ms (30 m × 250 mkm × 0,25 mkm). Results. 23 compounds (1 in the isomeric state) in fruits and 20 compounds (2 in the isomeric state) in the leaf of Elaeagnus angustifolia L. were identified. The main components of fruits were sitosterol (phytosterols) – 12.53 %, propyl acetate (esters of carboxylic acids) – 12.60 %, chamazulene (terpenes) – 11.97 % and palmitic acid (fatty acids) – 8.28 %. The main component of leaves were sitosterol (phytosterols) – 17.57 %, 1-(2-hydroxy-5-methylphenyl)-ethanone (ketone) – 8.35 %, phytol (terpenes) – 6.10 %. It is known from the literature that chamazulene has antioxidant, antinociceptive, cytotoxic activity. Sitosterol has anti-inflammatory and antidiabetic activity. Hexadecanoic (palmitic) acid has antimicrobial, antidiabetic and antioxidant properties. Phytol is characterized by a wide range of biological action – antimicrobial, antinociceptive, anti-inflammatory, antioxidant and cytotoxic. Conclusions. Based on the above, the olive can be considered as a source of antimicrobial, antinociceptive, anti-inflammatory, antioxidant, antidiabetic and cytotoxic drugs.

scholarly journals Research of the chemical composition of Artemisia tschernieviana Bess. by gas chromatography method with mass detection

2021 ◽  
Vol 14 (3) ◽  
pp. 282-286
Author(s):  
O. I. Panasenko ◽  
V. I. Mozul ◽  
O. M. Denysenko ◽  
I. I. Aksonova ◽  
V. V. Holovkin
Keyword(s):  
Chemical Composition ◽  
Propionic Acid ◽  
Succinic Anhydride ◽  
Raw Materials ◽  
Raw Material ◽  
Inflammatory Activity ◽  
Mass Detection ◽  
Chromatography Method ◽  
Mass Spectrometric Detector ◽  
Anti Inflammatory

The aim of the work was to study chromato-mass spectroscopic of Artemisia tschernieviana Bess. grass and to establish possible prospects for the use of this plant in medical practice. Materials and methods. Artemisia tschernieviana Bess. grass was chosen as the object of research. Raw materials were collected in July 2021 in the flowering phase (Zaporizhzhia). The tincture was obtained by maceration and the raw material was extracted with methyl alcohol at room temperature for 10 days according to the method of making tinctures. The study of the chemical composition of Artemisia tschernieviana Bess. Grass was carried out using gas chromatograph Agilent 7890B GC System (Agilent, Santa Clara, CA, USA) with mass spectrometric detector Agilent 5977 BGC/MSD (Agilent, Santa Clara, CA, USA) and chromatographic column DB-5ms (30 m × 250 μm × 0.25 μm). Results. During the study it was found that the composition of Artemisia tschernieviana Bess. grass includes 21 compounds (2 in the isomeric state). β-myrcene (17.22 %), sabinene (14.54 %), 2-(4a,8-dimethyl-7-oxo-1,2,3,4,4a,7-hexahydronaphthalen-2-yl) propionic acid (11.57 %), 2-dodecen-1-yl-succinic anhydride (10.84 %) and chamazulene (9.02 %) accounted for the largest percentage. According to the literature review, myrcene has antibacterial, anesthetic and analgesic effects. Sabinene is characterized by antibacterial action. 2-(4a,8-dimethyl-7-oxo-1,2,3,4,4a,7-hexahydronaphthalen-2-yl)-propionic acid is a fatty acid with possible antibacterial and anti-inflammatory activity. 2-dodecen-1-yl-succinic anhydride is used to produce anhydride-modified form of insulin that can be used in the treatment of diabetes. Hamazulen has anti-inflammatory activity. Conclusions. In view of all the above, we can conclude that Artemisia tschernieviana Bess. grass can be recommended for further research as a source of potential anti-inflammatory and antibacterial agents.

scholarly journals RELATIONSHIP BETWEEN ANTIOXIDANT PROPERTIES AND NUTRITIONAL COMPOSITION OF SOME GALACTOPOIETICS HERBS USED IN INDONESIA: A COMPARATIVE STUDY

2016 ◽  
Vol 8 (12) ◽  
pp. 236 ◽  
Author(s):  
Ade Chandra Iwansyah ◽  
Rizal M. Damanik ◽  
Lilik Kustiyah ◽  
Muhammad Hanafi
Keyword(s):  
Antioxidant Activity ◽  
Chemical Composition ◽  
Total Phenolics ◽  
Radical Scavenging Activity ◽  
Antioxidant Properties ◽  
Radical Scavenging ◽  
Nutritional Composition ◽  
Total Flavonoids ◽  
Wide Range ◽  
Phenolics Content

<p><strong>Objective: </strong>The objectives of this research were to evaluate and compare the antioxidant activity; phenolics and flavonoids contents; and chemical composition of some galactopoietic herbs used in Indonesia and to find a possible relationship between antioxidant activity; phenolics, flavonoids and chemical composition of these plants.</p><p><strong>Methods: </strong>A wide range of analytical parameters was studied, including yield; pH; water activity (a<sub>w</sub>); total color difference; phenolics and flavonoids content; moisture; ash; protein; fat; carbohydrate; fiber; calcium; zinc; magnesium; potassium; iron content; and the data were analyzed by partial least squares (PLS) regression analysis and principal component analysis (PCA) to evaluate the correlation between the parameters and classification of the plants. Folin–cioceltaeu assay, aluminum chloride assay and DPPH scavenging assay were used to evaluate of total phenolics content and free radical scavenging activity of the ethanolic extract of galactopoietic herbs.</p><p><strong>Results: </strong>All of the galactagogue herbs, <em>viz</em>. <em>Plectranthus amboinicus </em>(Lour.) (PA), <em>Sauropus androgynus</em> (SA), <em>Moringa oleifera</em> (MO), and <em>Carica papaya</em> leaves (CP) exhibited good results of TPC, TFC and antioxidant activity. MO contained the highest average of total phenolics content (53.89 mg GAE/g). SA with a ratio of total flavonoids to total phenolics (TF/TP) which is 1.59 contained the highest average of total flavonoids and antioxidant activity (IC<sub>50</sub>), 43.63 mg QE/g and 126.13 μg/ml, respectively, followed by MO&gt;CA&gt;PA. Based on PLS and PCA analysis, antioxidant activity correlated with fat, protein, phenolics content, flavonoids content and pH, but only the total flavonoids content correlated strongly with antioxidant activity.<strong></strong></p><p><strong>Conclusion: </strong>This provides useful data about the studied relationships and chemical patterns in some galactopoietic herbs used and provides a helpful tool for understanding much more about the interpretation of results from the experiments and the mechanism of biosynthesis in plants.</p>

scholarly journals Mitoprotective Effects of Centella asiatica (L.) Urb.: Anti-Inflammatory and Neuroprotective Opportunities in Neurodegenerative Disease

2021 ◽  
Vol 12 ◽  
Author(s):  
Jia Hui Wong ◽  
Anna M. Barron ◽  
Jafri Malin Abdullah
Keyword(s):  
Neurodegenerative Disease ◽  
Healthy Aging ◽  
Brain Aging ◽  
Antioxidant Properties ◽  
Centella Asiatica ◽  
Asiatic Acid ◽  
Wide Range ◽  
Anti Inflammatory

Natural products remain a crucial source of drug discovery for accessible and affordable solutions for healthy aging. Centella asiatica (L.) Urb. (CA) is an important medicinal plant with a wide range of ethnomedicinal uses. Past in vivo and in vitro studies have shown that the plant extract and its key components, such as asiatic acid, asiaticoside, madecassic acid and madecassoside, exhibit a range of anti-inflammatory, neuroprotective, and cognitive benefits mechanistically linked to mitoprotective and antioxidant properties of the plant. Mitochondrial dysfunction and oxidative stress are key drivers of aging and neurodegenerative disease, including Alzheimer’s disease and Parkinson’s disease. Here we appraise the growing body of evidence that the mitoprotective and antioxidative effects of CA may potentially be harnessed for the treatment of brain aging and neurodegenerative disease.

scholarly journals Zanjabeel (Zingiber officinale Roscoe.): An Evidence-Based Review of Anti-nociceptive, Anti-inflammatory, Antioxidant, and Antimicrobial Properties

2021 ◽  
pp. 26-35
Author(s):  
Fatima Khan ◽  
Mohd Nayab ◽  
Abdul Nasir Ansari
Keyword(s):  
Therapeutic Potential ◽  
Antioxidant Properties ◽  
Plant Secondary Metabolites ◽  
Zingiber Officinale ◽  
Extensive Study ◽  
The Body ◽  
Wide Range ◽  
Zingiber Officinale Roscoe ◽  
Medicinal Properties ◽  
Anti Inflammatory

Ginger has been appreciated for over 2500-3000 years in many parts of the world due to its numerous scientific properties. The ginger plant (Zingiber officinale Roscoe) belongs to the Zingiberaceae family. It is a known food and flavoring ingredient reputed for its wide range of medicinal properties that have been widely used in Chinese, Ayurvedic, and Unāni Tibb worldwide, since antiquity. Ginger has long been used to cure a variety of ailments, including diarrhea, stomach discomfort, indigestion, and nausea. It is a versatile herb with phenomenal phytotherapeutic and medicinal properties. Active ingredients available in ginger such as 6-gingerol, 6-shogaol, 6-paradol, and zingerone are responsible for upgrading enzyme actions and balancing circulation through rejuvenating the body with physical re-strengthening. Gingerols, the key phenolic plant secondary metabolites responsible for its distinct flavor and health benefits, are found in the rhizome of ginger Extensive study has been undertaken over the last two decades to uncover bioactive ingredients and the therapeutic potential of ginger. This review considers ginger's chemical composition and the most recent study findings on its possible health advantages, such as analgesic, anti-inflammatory, antibacterial, and antioxidant properties due to its phytochemistry. Overall, clinical trials are needed to confirm these prospective various health advantages of ginger in human subjects and the most efficacious dosage, based on the current body of scientific literature.

scholarly journals The study of compounds distilled with water vapor of Populus laurifolia Ledeb. leaves

2021 ◽  
pp. 56-62
Author(s):  
А. М. Рудник
Keyword(s):  
Water Vapor ◽  
Chemical Composition ◽  
Raw Materials ◽  
Total Content ◽  
Raw Material ◽  
Extensive Experience ◽  
Mass Spectrometric Detector ◽  
Depth Study ◽  
The Rich ◽  
The Village

Poplar plants (Populus L.) are one of the promising species for inclusion in the State Pharmacopoeia of Ukraine. To date, extensive experience has been accumulated in the use of extracts from buds, leaves and bark of various types of poplars in folk and official medicine as effective anti-inflammatory, antipyretic, analgetic, antibacterial agents. According to literature data only buds are pharmacopoeial raw materials in some countries of the world. Poplar leaves are of interest as a new promising type of medicinal plant raw material, since they have a chemical composition close to the buds, moreover, they are much easier to harvest and the possible volume of raw materials procurement is much larger. The laurel-leaf poplar (Populus laurifolia Ledeb.) is assigned to the section of balsamic poplars (Tacamahaca). It is grown in forest culture, used for landscaping and creation of field-protective plantations in Ukraine. Continuing a comprehensive pharmacognostic study of raw materials of plants of the genus poplar, purpose of this work was to study composition and content of compounds distilled with water vapor of leaves of laurel-leaf poplar cultivated in Ukraine. Leaves for research were harvested in June 2019, from trees growing on the shores of the Murom reservoir in the village of Russkiye Tishki, Kharkiv region (50°09′30″N 36°29′10″E). The composition of compounds distilled in water vapor was investigated on Agilent Technologies 6890N (USA) chromatograph with a 5973N mass spectrometric detector. The total content of compounds distilled with water vapor was 2 126.1 mg/kg. 46 compounds were identified. Terpenoids were presented by 20 compounds with a total content 1 444 mg/kg, the remaining 26 compounds were aromatic substances (256.2 mg/kg) and compounds of various groups (216.8 mg/kg). The dominant compounds in content were β-eudesmol (776.4 mg/kg), γ-eudesmol (298 mg/kg), α-bisabolol (125.9 mg/kg), eugenol (70.9 mg/kg). The data obtained indicate the rich chemical composition of leaves of laurel-leaf poplar and are the basis for further in-depth study of this raw material for assessment the possibility of using it as a medicine.

scholarly journals Phytochemical Characterization and Biological Evaluation of the Aqueous and Supercritical Fluid Extracts from Salvia sclareoides Brot

2017 ◽  
Vol 15 (1) ◽  
pp. 82-91
Author(s):  
Daniela Batista ◽  
Pedro L. Falé ◽  
Maria L. Serralheiro ◽  
Maria-Eduarda Araújo ◽  
Catarina Dias ◽  
...  
Keyword(s):  
Linoleic Acid ◽  
Supercritical Fluid ◽  
Antioxidant Properties ◽  
Biological Properties ◽  
Biological Evaluation ◽  
Cyclooxygenase 1 ◽  
Wide Range ◽  
Anti Inflammatory ◽  
Β Carotene

AbstractPlants belonging to the genus Salvia (Lamiaceae) are known to have a wide range of biological properties. In this work, extracts obtained from the aerial parts of Salvia sclareoides Brot. were evaluated to investigate their chemical composition, toxicity, bioactivity, and stability under in vitro gastrointestinal conditions. The composition of the supercritical fluid extract was determined by GC and GC-MS, while the identification of the infusion constituents was performed by HPLC-DAD and LC-MS. The in vitro cytotoxicity of both extracts (0-2 mg/mL) was evaluated in Caco-2 cell lines by the MTT assay. The anti-inflammatory and anticholinesterase activities were determined through the inhibition of cyclooxygenase-1 and acetylcholinesterase enzymes, while β-carotene/linoleic acid bleaching test and the DPPH assays were used to evaluate the antioxidant activity. The infusion inhibited cyclooxygenase-1 (IC50 = 271.0 μg/mL), and acetylcholinesterase (IC50 = 487.7 μg/ mL) enzymes, also demonstrated significant antioxidant properties, as evaluated by the DPPH (IC50 = 10.4 μg/mL) and β-carotene/linoleic acid (IC50 = 30.0 μg/mL) assays. No remarkable alterations in the composition or in the bioactivities of the infusion were observed after in vitro digestion, which supports the potential of S. sclareoides as a source of bioactive ingredients with neuroprotective, anti-inflammatory and antioxidant properties.

scholarly journals Comparison of the Antiaging and Protective Properties of Plants from the Apiaceae Family

2020 ◽  
Vol 2020 ◽  
pp. 1-16
Author(s):  
Nizioł-Łukaszewska Zofia ◽  
Zagórska-Dziok Martyna ◽  
Ziemlewska Aleksandra ◽  
Bujak Tomasz
Keyword(s):  
Antioxidant Properties ◽  
Centella Asiatica ◽  
Skin Condition ◽  
Skin Aging ◽  
Biologically Active ◽  
Raw Material ◽  
Plant Materials ◽  
Skin Cells ◽  
Wide Range ◽  
Migration Capacity

Plant materials play a very significant role as components of products being used both for medicinal and cosmetic purposes. Due to the high content of active substances, they can play an important role as extracts with antioxidant, regenerative, and antiaging properties. The skin aging process depends on various pathological and physiological processes, among which the degradation of extracellular matrix biomolecules such as collagen and elastin, which significantly affect the maintenance of good skin condition, is very important. The secondary metabolites and plant extracts may have collagenase and elastase inhibitory activity. This activity is mainly due to the high content of a wide range of various biologically active compounds, such as polyphenols, which include, among others, flavonoids, phenolic acids, tocopherols, and tannins. The work involved a comprehensive assessment of the plant from Apiaceae family such as Meum athamanticum L., Centella asiatica L., and Aegopodium podagraria L. extract as a multifunctional raw material. During study antioxidant properties, phenolic compounds and flavonoids content, effect on collagenase and elastase enzyme activity (antiaging effect), cytotoxic properties on skin cells (keratinocytes and fibroblasts), and cell migration capacity were analyzed. It has been shown that the highest antioxidant capacity can be observed for the extract of herb of Aegopodium podagraria L. When the concentration reached 5% all tested extracts had a positive effect on the cell proliferation of both keratinocytes and fibroblasts. It turned out that the most promising inhibitor of collagenase and elastase enzymes was the extract from Aegopodium podagraria, which inhibits the activity of both enzymes by over 70% in the concentration of 5% positively affecting the condition of skin cells.

scholarly journals Development of meat and fish formed semi-finished products for herodietic food

2021 ◽  
pp. 74-80
Author(s):  
Liudmyla Peshuk ◽  
Iryna Simonova
Keyword(s):  
Chemical Composition ◽  
Raw Materials ◽  
Antioxidant Properties ◽  
The Elderly ◽  
Raw Material ◽  
Poultry Meat ◽  
Scientific Publications ◽  
Organoleptic Evaluation ◽  
Relevant Today ◽  
Minced Meat

To improve the health of the population, it is necessary to develop products that contain natural ingredients with antioxidant properties. The development of the technology of meat and fish molded semi-finished products of the Ayurvedic direction is relevant today. The main raw material was poultry meat. After conducting a literary review of scientific publications and comparing the chemical composition of different types of fish, we selected sea fish ‒ hake, pollock and oceanic ‒ saithe, haddock with amount of protein. The technology of molded meat and fish products allows to introduce into the composition of semi-finished products multifunctional ingredients that enrich the chemical composition of the product, increase the nutritional value, improve its taste, and expand the range of processing of raw materials without production waste. This technology makes it possible to create meat and fish semi-finished products, with a targeted change in the chemical composition, corresponding to the physiological needs of the human body, especially for children, the elderly. To identify the most optimal ratios between meat and fish raw materials, have been developed 21 samples of minced meat and fish systems. A study of the organoleptic evaluation of meat and fish semi-finished products was carried out, with the introduction of fish raw materials into the recipe from 10 to 50%. The detailed profilograms were built on the basis of the research results. The general comparative analysis allows us to state that among all the presented research samples, the best marks were obtained for sample No. 5 and No. 4 using ocean fish (haddock in the amount of 50%; saithe fish in the amount of 40%) in terms of taste, smell and consistency. As a result of studies of the physicochemical indicators of the developed minced meat and fish systems, it was found that almost all prototypes were characterized by an increased moisture content with an increase in the amount of fish raw materials. For further research, samples were selected whose recipes were the most optimal in terms of the ratio of meat and fish raw materials, namely chicken fillet and haddock fish in a ratio of 50: 50%, and chicken fillet and saithe fish ‒ 60: 40%.

scholarly journals ХИМИЧЕСКИЙ СОСТАВ И АНТИОКСИДАНТНЫЕ СОЕДИНЕНИЯ МУЧНОЙ КОМПОЗИТНОЙ СМЕСИ С ДОБАВЛЕНИЕМ БРУСНИКИ И ПАЖИТНИКА

2019 ◽  
Author(s):  
L.V. Anisimova ◽  
O.I.A. Soltan
Keyword(s):  
Chemical Composition ◽  
Vitamin C ◽  
Wheat Gluten ◽  
Antioxidant Properties ◽  
Natural Antioxidants ◽  
Raw Material ◽  
Antioxidant Compounds ◽  
Fenugreek Seed ◽  
Composite Mixture ◽  
Oat Flour

The effect of fenugreek and lingonberry supplements, containing natural antioxidants and a lot of important nutrition components, on the chemical composition and antioxidant content of flour mixture based on whole oat flour were investigated. Oat flour was produced using hydrothermal treatment, which included intensive moistening of the grain in the vacuum unit, standing, and drying. In addition to whole oat flour, the highgrade wheat flour, dry wheat gluten, and fenugreek seed powder or dried lingonberry powder were added to the flour composite mixture. The chemical composition of raw material and flour composite such as protein, carbohydrates, fat, and moisture was determined. Besides, antioxidant components, like Vitamin C and flavonoids in raw material and flour composites were investigated. From results, it has been established that adding fenugreek seed powder and dried lingonberry powder to flour composite based on oat flour leads to significant enhancing in the chemical composition and antioxidant compounds: the addition of the fenugreek seed powder led to the increase of protein content in the flour composite. Furthermore, adding dried lingonberry powder and fenugreek seed powder led to a slight effect on carbohydrates. The addition of fenugreek seed powder has the greatest effect on the content of flavonoids. In addition, vitamin C was significantly increased by the addition of lingonberry. According to, the results of our research can recommend the addition of fenugreek seed powder and lingonberry to oatwheat flour composite leading to improvement of its nutritional and antioxidant properties.

PROGNOSTIC VIEW ON THE PROSPECTS OF PROCESSING WHEY

2018 ◽  
Author(s):  
А.Г. ХРАМЦОВ
Keyword(s):  
Chemical Composition ◽  
Raw Material ◽  
Cottage Cheese ◽  
Animal Origin ◽  
Industrial Processing ◽  
Wide Range

Рассмотрена молочная сыворотка – побочный продукт при производстве сыров, творога и казеина как универсальное сырье животного происхождения. Обобщены результаты исследований российских и зарубежных ученых химического состава молочной сыворотки, и показаны основные направления ее промышленной переработки. Представлены широкий спектр продуктов из молочной сыворотки и направления их использования в разных отраслях промышленности. Whey is a by-product in the production of cheese, cottage cheese and casein as a universal raw material of animal origin is considered. The results of studies of Russian and foreign scientists of the chemical composition of whey are summarized. The main directions of its industrial processing are shown. A wide range of products from whey and directions of their use in different industries are presented.

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