scholarly journals Synopsis of symptoms of COVID-19 during second wave of the pandemic in India

Author(s):  
Prafull Kamble ◽  
Vandana Daulatabad ◽  
Nitin John ◽  
Jyoti John

Abstract COVID-19 was caused by the original coronavirus, severe acute respiratory syndrome associated coronavirus-2 (SARS CoV2), which originated in Wuhan, China. COVID-19 had a large breakout of cases in early 2020, resulting in an epidemic that turned into a pandemic. This quickly enveloped the global healthcare system. The principal testing method for COVID-19 detection, according to the WHO, is reverse transcription polymerase chain reaction (RT-PCR). Isolation of patients, quarantine, masking, social distancing, sanitizer use, and complete lockdown were all vital health-care procedures for everyone. With the ‘new normal’ and vaccination programmes, the number of cases and recovered patients began to rise months later. The easing of restrictions during the plateau phase resulted in a rebound of instances, which hit the people with more ferocity and vengeance towards the start of April 2021. Coronaviruses have evolved to cause respiratory, enteric, hepatic, and neurologic diseases, resulting in a wide range of diseases and symptoms such as fever, cough, myalgia or fatigue, shortness of breath, muscle ache, headache, sore throat, rhinorrhea, hemoptysis, chest pain, nausea, vomiting, diarrhoea, anosmia, and ageusia. Coronavirus infections can be mild, moderate, or severe in intensity. COVID-19 pulmonary dysfunction includes lung edoema, ground-glass opacities, surfactant depletion, and alveolar collapse. Patients who presented with gastrointestinal (GI) symptoms such as anorexia, nausea, vomiting, or diarrhoea had a higher risk of negative outcomes. COVID-19’s influence on cognitive function is one of COVID-19’s long-term effects. More clinical situations need to be reviewed by healthcare professionals so that an appropriate management protocol may be developed to reduce morbidity and death in future coming third/fourth wave cases.

HortScience ◽  
1997 ◽  
Vol 32 (3) ◽  
pp. 436E-436
Author(s):  
Martin P.N. Gent

The persistence of effects of paclobutrazol or uniconazol on stem elongation was determined for several years after large-leaf Rhododendron and Kalmia latifolia were treated with a single-spray application of these triazol growth-regulator chemicals. Potted plants were treated in the second year from propagation, and transplanted into the field in the following spring. The elongation of stems was measured in the year of application and in the following 2 to 4 years. Treatments with a wide range of doses were applied in 1991, 1992, or 1995. For all except the most-dilute applications, stem elongation was retarded in the year following application. At the highest doses, stem growth was inhibited 2 years following application. The results could be explained by a model of growth regulator action that assumed stem elongation was inversely related to amount of growth regulator applied. The dose response coefficient for paclobutrazol was less than that for uniconazol. The dose that inhibited stem elongation one-half as much as a saturating dose was about 0.5 and 0.05 mg/plant, for paclobutrazol and uniconazol, respectively. The dose response coefficient decreased exponentially with time after application, with an exponential time constant of about 2/year. The model predicted a dose of growth regulator that inhibited 0.9 of stem elongation immediately after application would continue to inhibit 0.5 of stem elongation in the following year.


Author(s):  
Paulina Żebrowska ◽  
Izabela Łaczmańska ◽  
Łukasz Łaczmański

Research on the use of fecal microbiota transplantation (FMT) in the treatment of disorders related to digestive system ailments in children with autism spectrum disorders (ASDs) is a new attempt in a therapeutic approach. There are very little scientific evidences available on this emerging alternative method. However, it appears to be interesting not only because of its primary outcome, relieving the gastrointestinal (GI) symptoms, but also secondary therapeutic effect of alleviating autistic behavioral symptoms. FMT seems to be also promising method in the treatment of another group of pediatric patients, children with inflammatory bowel disease (IBD). The aim of this study is to discuss the potential use of FMT and modified protocols (MTT, microbiota transfer therapy) in the treatment of GI disorders in ASD children supported by reports on another disease, IBD concerning pediatric patients. Due to the few reports of the use of FMT in the treatment of children, these two patients groups were selected, although suffering from distant health conditions: neurodevelopmental disorder and gastrointestinal tract diseases, because of the the fact that they seem related in aspects of the presence of GI symptoms, disturbed intestinal microbiota, unexplained etiology of the condition and age range of patients. Although the outcomes for all are promising, this type of therapy is still an under-researched topic, studies in the group of pediatric patients are sparse, also there is a high risk of transmission of infectious and noninfectious elements during the procedure and no long-term effects on global health are known. For those reasons all obtained results should be taken with a great caution. However, in the context of future therapeutic directions for GI observed in neurodevelopmental disorders and neurodegenerative diseases, the topic seems worthy of attention.


Author(s):  
Joshua Clark Davis

Chapter four investigates a wide range of businesses that feminists created in the 1970s, including credit unions, printing presses, bookstores, and mail-order catalogs. Arguing that male-controlled, American corporate capitalism was one of society’s most powerful perpetuators of sexism and patriarchy, feminist entrepreneurs believed their products and services offered women economic independence from men and publicized the cause of women’s liberation in the wider public. Feminist businesses were particularly interested in creating democratic workplaces with collectives and other participatory organizational models and they sought to operate storefronts as autonomous “free spaces” for their movement, as well as for women more generally. The decline of second-wave feminism would however prove very challenging to feminist businesses in the 1980s, as did the difficulties of operative collectives in the long term.


2008 ◽  
Vol 147 (1) ◽  
pp. 31-42 ◽  
Author(s):  
H. ZHANG ◽  
M. XU ◽  
F. ZHANG

SUMMARYRice (Oryza sativaL.), wheat (Triticum aestivumL.) and maize (Zea maysL.) are the main crops grown in China. Applying organic manures is an important practice in sustaining soil fertility and agricultural productivity in these cropping systems. The current paper presents the effects of manure application on grain yields in nine long-term experiments that consist of one continuous maize, four wheat–maize and four rice-based cropping systems across a wide range of agro-ecological regions in China. The study shows that regular manure application can increase soil organic carbon (SOC) and grain yield across all the sites. Overall, regular use of manure results in larger increases in SOC in the maize and wheat–maize systems than in the rice-based systems. Application of manure tends to increase the grain yield in the maize and wheat–maize systems during the final years, but increases the grain yield in the rice-based systems during the initial years of the long-term experiments. There is only one site that shows significant improvement in the yield trend in association with the application of manure. The effects of manure on yield trends are probably determined by the initial yield and/or the ‘organic C effect’ that may cause gradual improvements in SOC and soil physical properties.


2000 ◽  
Vol 1 (4) ◽  
pp. 385-419 ◽  
Author(s):  
J. Michael Orszag ◽  
Dennis J. Snower

Abstract This paper explores the optimal design of subsidies for hiring unemployed workers (`employment vouchers' for short) in the context of a simple dynamic model of the labour market. Focusing on the short-term and long-term effects of the vouchers on employment and unemployment, the analysis shows how the optimal policy depends on the rates of hiring and firing, and on the problems of displacement and deadweight. It also examines the roles of the government budget constraint and of the level of unemployment benefits in optimal policy design. We calibrate the model and evaluate the effectiveness of employment vouchers in reducing unemployment for a wide range of feasible parameters.


2016 ◽  
Vol 24 (2) ◽  
pp. 243-262 ◽  
Author(s):  
Laron K. Williams

A dominant trend in models with binary outcomes is to control for unmodeled duration dependence by including temporal dependence variables. A second, distinct trend is to interpret both the short- and long-term effects of explanatory variables in autoregressive models. While the first trend is nearly ubiquitous in models with binary outcomes, the second trend has yet to be applied consistently beyond models with continuous outcomes. While scholars use temporal splines and cubic polynomials to model the underlying hazard rate, they have neglected the fact that this causes the explanatory variables to have a long-term effect (LTE) by modifying the future values of the temporal dependence variables. In this article, I propose a simple technique that estimates a wide range of probabilistic LTEs in models with temporal dependence variables. These effects can range from simple LTEs for a one-time change in an explanatory variable to more complex scenarios where effects change in magnitude with time and compound across repeated events. I then replicate Clare's (2010, Ideological fractionalization and the international conflict behavior of parliamentary democracies.International Studies Quarterly54:965–87) examination of the influence of government fractionalization on conflict behavior to show that failing to interpret the results within the context of temporal dependence underestimates the total impact of fractionalization by neglecting LTEs.


2017 ◽  
Vol 45 (2) ◽  
pp. 407-438 ◽  
Author(s):  
William Parker ◽  
Chi Dang Hornik ◽  
Staci Bilbo ◽  
Zoie E. Holzknecht ◽  
Lauren Gentry ◽  
...  

The wide range of factors associated with the induction of autism is invariably linked with either inflammation or oxidative stress, and sometimes both. The use of acetaminophen in babies and young children may be much more strongly associated with autism than its use during pregnancy, perhaps because of well-known deficiencies in the metabolic breakdown of pharmaceuticals during early development. Thus, one explanation for the increased prevalence of autism is that increased exposure to acetaminophen, exacerbated by inflammation and oxidative stress, is neurotoxic in babies and small children. This view mandates extreme urgency in probing the long-term effects of acetaminophen use in babies and the possibility that many cases of infantile autism may actually be induced by acetaminophen exposure shortly after birth.


2018 ◽  
Vol 49 (1) ◽  
pp. 26-31
Author(s):  
A. Cidlinová ◽  
Z. Wittlingerová ◽  
M. Zimová ◽  
T. Chrobáková ◽  
A. Petruželková

Abstract Wastewater from medical facilities contains a wide range of chemicals (in particular pharmaceuticals, disinfectants, heavy metals, contrast media, and radionuclides) and pathogens, therefore it constitutes a risk to the environment and human health. Many micropollutants are not efficiently eliminated during wastewater treatment and contaminate both surface water and groundwater. As we lack information about the long-term effects of low concentrations of micropollutants in the aquatic environment, it is not possible to rule out their adverse effects on aquatic organisms and human health. It is, therefore, necessary to focus on the evaluation of chronic toxicity in particular when assessing the environmental and health risks and to develop standards for the regulation of hazardous substances in wastewater from medical facilities on the basis of collected data. Wastewater from medical facilities is a complex mixture of many compounds that may have synergetic, antagonistic or additive effects on organisms. To evaluate the influence of a wide range of pollutants contained in the effluents from medical facilities on aquatic ecosystems, it is necessary to determine their ecotoxicity.


1994 ◽  
Vol 17 (4) ◽  
pp. 669-674 ◽  
Author(s):  
Ed Cairns

The papers presented in this special section provide an introduction to the area of research on the effects of political violence on children. The articles cover a wide range of topics from the well-researched question of stress and coping to the less often investigated questions of the development of aggression, the long-term effects of political violence, and the evaluation of attempts at reconciliation. In addition, they represent those geographical areas which at present dominate work in this area the Middle East, Northern Ireland, and South Africa. They also illustrate emerging debates concerning resilience versus vulnerability and the effectiveness of outsiders versus insiders as investigators. The research reported here also points to the need for more cross-cultural work. Finally, it is argued that there is a need to understand the collective nature of political violence. This has implications not only for future research methods but, more importantly, for the development of a theoretical basis that is needed for work in this area.


PEDIATRICS ◽  
1982 ◽  
Vol 70 (4) ◽  
pp. 581-581
Author(s):  

The growing threat of thermonuclear war and the continued development and proliferation of nuclear weapons have compelled us as physicians to examine in detail the consequences such a war would have on the people of our nations and of the world, whose health and survival are our professional commitment. During the past several days, physicians and scientists from 31 countries have gathered to consider relevant data on the immediate and long term effects of a nuclear conflict. We were unanimous in concluding that: . . . The growth in sheer numbers of nuclear weapons and the increasing complexity and sophistication of delivery systems increase the possibility that a nuclear conflict may be triggered by tragic accident. Physicians are aware from their daily work that technologic systems are liable to malfunction and that human performance may fail because of mental derangement or even simple error. Whereas such failures in medicine may jeopardise a single life, the malfunctioning of military systems may now endanger the existence of humanity....


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