Legal and Biological Perspectives of “Plant Variety” in IPR Context

2009 ◽  
Vol 6 (1) ◽  
Author(s):  
Mohammad Reza Parvin
Keyword(s):  
Genetic Engineering ◽  
Good Reason ◽  
Trips Agreement ◽  
Biological Processes ◽  
Human Intervention ◽  
Genetic Inheritance ◽  
Plant Variety ◽  
Long Time ◽  
The Relationship ◽  
Biological Differences

AbstractThe possibilities of human intervention on plants were limited for a long time to simple handling of selection or crossing which were always regarded as essentially biological processes. However, the development of the genetic engineering in the field of plants and the possibilities of plants genetic inheritance handling by the advanced techniques, such as the recombining DNA, evoked debates over the patentability of plant inventions.According to Article 27.3(b) of the TRIPS Agreement, Members may exclude “plants” from patentability, but they shall provide for the protection of “plant varieties” either by patent or by an effectiveThe relationship between plant breeder's rights (as aIn view of the importance of the decision of countries to protect plant varieties, the study assesses also the legal positions adopted by jurisprudence or doctrine to determine the scope of the plant varieties exception.It is concluded that the actual and biological differences between “plant” and “plant variety” could give good reason for interpreting the two terms in different ways.

The Problem of Identifying and Modeling the Relationship between Monetary Factor and Inflation in the Russian Economy

2008 ◽  
pp. 61-76
Author(s):  
A. Porshakov ◽  
A. Ponomarenko
Keyword(s):  
Money Supply ◽  
Money Demand ◽  
Russian Economy ◽  
Long Run ◽  
Complex Approach ◽  
Wide Range ◽  
Long Time ◽  
The Relationship ◽  
Supply Side Factors

The role of monetary factor in generating inflationary processes in Russia has stimulated various debates in social and scientific circles for a relatively long time. The authors show that identification of the specificity of relationship between money and inflation requires a complex approach based on statistical modeling and involving a wide range of indicators relevant for the price changes in the economy. As a result a model of inflation for Russia implying the decomposition of inflation dynamics into demand-side and supply-side factors is suggested. The main conclusion drawn is that during the recent years the volume of inflationary pressures in the Russian economy has been determined by the deviation of money supply from money demand, rather than by money supply alone. At the same time, monetary factor has a long-run spread over time impact on inflation.

CASC15：A tumor-associated long non-coding RNA

2020 ◽  
Vol 26 ◽  
Author(s):  
Bei Wang ◽  
Wen Xu ◽  
Yuxuan Cai ◽  
Chong Guo ◽  
Gang Zhou ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Therapeutic Target ◽  
Cancer Colorectal ◽  
Tumor Development ◽  
Pathophysiological Mechanism ◽  
Biological Processes ◽  
Non Coding Rna ◽  
Cancer Côlon ◽  
The Relationship ◽  
Long Non Coding Rna

Background: CASC15, one of long non-coding RNA, is involved in the regulation of many tumor biological processes, and is expected to become a new biological therapeutic target. This paper aims to elucidate the pathophysiological function of CASC15 in various tumors. Methods: The relationship between CASC15 and tumors was analyzed by searching references, and summarizes the specific pathophysiological mechanism of CASC15. Results: LncRNA CASC15 is closely related to tumor development, and has been shown to be abnormally high expressed in all kinds of tumors, including breast cancer, cervical cancer, lung cancer, hepatocellular carcinoma, gastric cancer, bladder cancer, colon cancer, colorectal cancer, cardiac hypertrophy, intrahepatic cholangiocarcinoma, leukemia, melanoma, tongue squamous cell carcinoma, nasopharyngeal carcinoma. However, CASC15 has been found to be downexpressed abnormally in ovarian cancer, glioma and neuroblastoma. Besides, it is identified that CASC15 can affect the proliferation, invasion and apoptosis of tumors. Conclusion: LncRNA CASC15 has the potential to become a new therapeutic target or marker for a variety of tumors.

Psychology: Volume 5

2019 ◽  
Keyword(s):  
World View ◽  
Science Volume ◽  
Western World ◽  
Mental Life ◽  
Long Time ◽  
The Difference ◽  
New Perspective ◽  
Indian Setting ◽  
The Mind ◽  
The Relationship

This survey of research on psychology in five volumes is a part of a series undertaken by the ICSSR since 1969, which covers various disciplines under social science. Volume Five of this survey, Explorations into Psyche and Psychology: Some Emerging Perspectives, examines the future of psychology in India. For a very long time, intellectual investments in understanding mental life have led to varied formulations about mind and its functions across the word. However, a critical reflection of the state of the disciplinary affairs indicates the dominance of Euro-American theories and methods, which offer an understanding coloured by a Western world view, which fails to do justice with many non-Western cultural settings. The chapters in this volume expand the scope of psychology to encompass indigenous knowledge available in the Indian tradition and invite engaging with emancipatory concerns as well as broadening the disciplinary base. The contributors situate the difference between the Eastern and Western conceptions of the mind in the practice of psychology. They look at this discipline as shaped by and shaping between systems like yoga. They also analyse animal behaviour through the lens of psychology and bring out insights about evolution of individual and social behaviour. This volume offers critique the contemporary psychological practices in India and offers a new perspective called ‘public psychology’ to construe and analyse the relationship between psychologists and their objects of study. Finally, some paradigmatic, pedagogical, and substantive issues are highlighted to restructure the practice of psychology in the Indian setting.

scholarly journals The impacts of mediating the work environment on the mode choice in work trips

2021 ◽  
Vol 11 (1) ◽  
pp. 592-605
Author(s):  
Melchior Bria ◽  
Ludfi Djakfar ◽  
Achmad Wicaksono
Keyword(s):  
Work Environment ◽  
Public Transportation ◽  
Travel Behavior ◽  
Structural Equation ◽  
Mode Choice ◽  
Equation Modeling ◽  
Rapid Transit ◽  
Long Time ◽  
Socio Economic Variables ◽  
The Relationship

Abstract The impacts of work characteristics on travel mode choice behavior has been studied for a long time, focusing on the work type, income, duration, and working time. However, there are no comprehensive studies on the influence of travel behavior. Therefore, this study examines the influence of work environment as a mediator of socio-economic variables, trip characteristics, transportation infrastructure and services, the environment and choice of transportation mode on work trips. The mode of transportation consists of three variables, including public transportation (bus rapid transit and mass rapid transit), private vehicles (cars and motorbikes), and online transportation (online taxis and motorbike taxis online). Multivariate analysis using the partial least squares-structural equation modeling method was used to explain the relationship between variables in the model. According to the results, the mediating impact of work environment is significant on transportation choices only for environmental variables. The mediating mode choice effect is negative for public transportation and complimentary for private vehicles and online transportation. Other variables directly affect mode choice, including the influence of work environment.

scholarly journals Dynamics of life expectancy and life span equality

2020 ◽  
Vol 117 (10) ◽  
pp. 5250-5259 ◽  
Author(s):  
José Manuel Aburto ◽  
Francisco Villavicencio ◽  
Ugofilippo Basellini ◽  
Søren Kjærgaard ◽  
James W. Vaupel
Keyword(s):  
Life Expectancy ◽  
Life Span ◽  
Health Policies ◽  
Public Health Policies ◽  
Dynamic Relationship ◽  
Mortality Increase ◽  
Long Time ◽  
Underlying Causes ◽  
The Relationship ◽  
Over Time

As people live longer, ages at death are becoming more similar. This dual advance over the last two centuries, a central aim of public health policies, is a major achievement of modern civilization. Some recent exceptions to the joint rise of life expectancy and life span equality, however, make it difficult to determine the underlying causes of this relationship. Here, we develop a unifying framework to study life expectancy and life span equality over time, relying on concepts about the pace and shape of aging. We study the dynamic relationship between life expectancy and life span equality with reliable data from the Human Mortality Database for 49 countries and regions with emphasis on the long time series from Sweden. Our results demonstrate that both changes in life expectancy and life span equality are weighted totals of rates of progress in reducing mortality. This finding holds for three different measures of the variability of life spans. The weights evolve over time and indicate the ages at which reductions in mortality increase life expectancy and life span equality: the more progress at the youngest ages, the tighter the relationship. The link between life expectancy and life span equality is especially strong when life expectancy is less than 70 y. In recent decades, life expectancy and life span equality have occasionally moved in opposite directions due to larger improvements in mortality at older ages or a slowdown in declines in midlife mortality. Saving lives at ages below life expectancy is the key to increasing both life expectancy and life span equality.

A Research on the Morphology and Composition of Flocs (Part 1: Floc Breaage Disregarded)

2013 ◽  
Vol 726-731 ◽  
pp. 1566-1572 ◽  
Author(s):  
Shi Qiang Ding ◽  
Qing Na Li ◽  
Xin Rong Pang ◽  
Ji Run Xu
Keyword(s):  
Dimensional Space ◽  
Three Dimensional ◽  
New Classification ◽  
Suspension Viscosity ◽  
Primary Particles ◽  
Long Time ◽  
Relationship Of ◽  
The Relationship ◽  
Three Dimensional Space ◽  
Floc Breakage

The characteristics of flocs aggregated in flocculation have been paid more and more attention for a long time. In this paper, a new classification and analyses method dealing with the flocs is developed. The flocs formed after flocculation is divided into four kinds, including the left primary particles, linear flocs with all component particles in a line, planar flocs with all component particles on a plane and volumetric flocs with all component particles in a three-dimensional space. By analyzing the formation approaches of different kind of flocs regardless of the floc breakage, the number of every kind of floc is analyzed to be related with the suspension concentration mathematically. After comparing the different items in the models describing the relationship of floc number and concentration, a series of simplified expressions are presented. Lastly, a mathematical equation relating the measurable suspension viscosity with the numbers of different flocs is obtained.

The Relationship of Undifferentiated Mesenchymal Cells to TMJ Articular Tissue Thickness

1992 ◽  
Vol 71 (11) ◽  
pp. 1816-1821 ◽  
Author(s):  
C.A. Bibb ◽  
A.G. Pullinger ◽  
F. Baldioceda
Keyword(s):  
Soft Tissue ◽  
Inverse Relationship ◽  
Biological Processes ◽  
Spearman Correlation ◽  
Articular Eminence ◽  
Tissue Thickness ◽  
Cartilage Layer ◽  
Soft Tissue Thickness ◽  
Relationship Of ◽  
The Relationship

Undifferentiated mesenchymal (UM) cells, the progenitor cells of the cartilage layer, have been assigned a significant role in TMJ articular tissue maintenance. This was based on reports of UM cell reduction with increased soft-tissue thickness for the condyle and temporal component. However, the strength of this inverse relationship was not presented and remained unclear. The purpose of the present study was to assess the strength of the correlation between UM cell presence and soft-tissue thickness in young adult TMJs at autopsy. Sagittal histological sections from the central thirds of 50 joints were evaluated with respect to articular soft-tissue thickness, histological character, and UM cell presence in the condyle and temporal component. The superior sector ofthe condyle and the articular eminence showed the greatest variability in soft-tissue thickness and were the only areas to show localized UM cell absence. The eminence was the only location to show an inverse relationship between soft-tissue thickness and UM cell presence, and this was consistent in both an ANOVA (p = 0.0016) and a Spearman correlation analysis. However, the strength of this correlation was only moderate (rho = -0.52), and no such relationship was observed in any other location. This study suggests that the relationship between UM cell presence and soft-tissue thickness is more complex than previously hypothesized and that the contribution of UM cells to articular tissue maintenance has been overstated, while other biological processes were overlooked.

The Calculation Method and Experimental Research on Throttling Pressure Drop during Kill a Well

2012 ◽  
Vol 229-231 ◽  
pp. 495-498
Author(s):  
Hui Xin Liu ◽  
Xian Min Yang ◽  
Cheng Tao Li ◽  
Xiang Cheng
Keyword(s):  
Pressure Drop ◽  
Calculation Method ◽  
Engineering Practice ◽  
Exploration Process ◽  
Throttle Valve ◽  
Long Time ◽  
Valve Opening ◽  
Casing Pressure ◽  
The Relationship ◽  
Control Accuracy

There is a common problem during kill a well, which is how to quickly and accurately control the surface casing pressure according to the requirements for killing a well. A step-by-step exploration process is employed on operation sites. Continuously adjusting throttle valve to acquire surface casing pressure may lead to failure of kill operation because of its long time and low control accuracy. Obviously, if the calculation problems of throttling drawdown can be resolved,the relationship between drawdown and throttle valve opening can be found and the course of explorating can be converted into a straight course.Then the success rate of killing well can be improved. More importantly, this can make automatic controll of surface casing pressure possible. The paper built the calculation method of throttling pressure drop by theoretical analysis and verified the calculation method by adopting it into field test. The result has showed that the calculation method of throttling pressure drop coincides with experimental results and it can be used in engineering practice.

scholarly journals Nanodrug Delivery Systems Modulate Tumor Vessels to Increase the Enhanced Permeability and Retention Effect

2021 ◽  
Vol 11 (2) ◽  
pp. 124
Author(s):  
Dong Huang ◽  
Lingna Sun ◽  
Leaf Huang ◽  
Yanzuo Chen
Keyword(s):  
Blood Vessels ◽  
Tumor Vessels ◽  
Epr Effect ◽  
Nanodrug Delivery ◽  
Enhanced Permeability And Retention ◽  
Macromolecular Drugs ◽  
Long Time ◽  
Vessel Network ◽  
Tumor Blood Vessels ◽  
The Relationship

The use of nanomedicine for antitumor therapy has been extensively investigated for a long time. Enhanced permeability and retention (EPR) effect-mediated drug delivery is currently regarded as an effective way to bring drugs to tumors, especially macromolecular drugs and drug-loaded pharmaceutical nanocarriers. However, a disordered vessel network, and occluded or embolized tumor blood vessels seriously limit the EPR effect. To augment the EPR effect and improve curative effects, in this review, we focused on the perspective of tumor blood vessels, and analyzed the relationship among abnormal angiogenesis, abnormal vascular structure, irregular blood flow, extensive permeability of tumor vessels, and the EPR effect. In this commentary, nanoparticles including liposomes, micelles, and polymers extravasate through the tumor vasculature, which are based on modulating tumor vessels, to increase the EPR effect, thereby increasing their therapeutic effect.

Research progress in predicting DNA methylation modifications and the relation with human diseases

2021 ◽  
Vol 28 ◽  
Author(s):  
Chunyan Ao ◽  
Lin Gao ◽  
Liang Yu
Keyword(s):  
Dna Methylation ◽  
Eukaryotic Cell ◽  
Machine Learning Algorithms ◽  
Research Progress ◽  
Epigenetic Mechanisms ◽  
Biological Processes ◽  
Prediction Tools ◽  
Transformation Mechanisms ◽  
The Relationship ◽  
Treatment And Diagnosis

: DNA methylation is an important mode of regulation in epigenetic mechanisms, and it is one of the research foci in the field of epigenetics. DNA methylation modification affects a series of biological processes, such as eukaryotic cell growth, differentiation and transformation mechanisms, by regulating gene expression. In this review, we systematically summarized the DNA methylation databases, prediction tools for DNA methylation modification, machine learning algorithms for predicting DNA methylation modification, and the relationship between DNA methylation modification and diseases such as hypertension, Alzheimer's disease, diabetic nephropathy, and cancer. An in-depth understanding of DNA methylation mechanisms can promote accurate prediction of DNA methylation modifications and the treatment and diagnosis of related diseases.

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