scholarly journals Antimicrobial activity extracts from three species of fresh water algae and used against some pathogenic microorganisms and analysis of minerals in algal species

2020 ◽  
Planta Medica ◽  
2011 ◽  
Vol 77 (12) ◽  
Author(s):  
VR Santos ◽  
VA Noronha ◽  
JC Silva ◽  
FF Silva ◽  
TF Machado ◽  
...  

Antibiotics ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 552
Author(s):  
Suraj Arora ◽  
Shahabe Saquib ◽  
Youssef Algarni ◽  
Mohammed Kader ◽  
Irfan Ahmad ◽  
...  

Background and objectives: This study aimed to evaluate the synergistic antimicrobial activity of extracts obtained from Salvadora persica (Miswak), Commiphora molmol (myrrh) and Azadirachta indica (neem) in combination with commercially available antimicrobial agents: penicillin, tetracycline, ofloxacin and fluconazole on endodontic pathogens such as Enterococcus faecalis, Streptococcus mitis, Actinomyces naeslundii and Candida albicans. Materials and Methods: Microbiological samples from the root canals of the teeth undergoing retreatment were taken using sterile paper points kept at full length in the canal for 30 seconds. The disc diffusion method was used to check the susceptibility of microbes to the plant extracts and antimicrobials by measuring the diameter of the inhibition zones. Against the microbes, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC)/minimum fungicidal concentration (MFC) of the plant extracts were assessed. The fractional inhibitory concentration index (FICI) was used to estimate the synergistic effect of plant extracts combined with antimicrobials against the resistant endodontic microbes. Results: The findings clearly indicate the effectiveness of all the three plant extracts, Commiphora molmol, Azadirachta indica, Salvadora persica, against all the experimental pathogenic microorganisms except for the ineffectiveness of Azadirachta indica, Salvadora persica against Candida albicans. Maximum antimicrobial activity was displayed by Azadirachta indica against Enterococcus faecalis (MIC = 0.09 ± 1.2 mg/mL, MBC = 0.78 ± 1.25 mg/mL) and the minimum antimicrobial activity was displayed by Commiphora molmol against Actinomyces naeslundii (MIC = 12.5 ± 3.25 mg/mL, MBC = 100 ± 3.75 mg/mL). The best synergy was displayed by Commiphora molmol with fluconazole against Candida albicans (FICI = 0.45). Conclusions: The current study delineates the variable antimicrobial activity of plant extracts against the experimental endodontic pathogenic microorganisms. Plant extracts in conjunction with various antimicrobials can be valuable aids in combating relatively resistant endodontic microorganisms that have been the cause of worry in recent years, leading to failure even in treatment procedures following all required protocols.


1991 ◽  
Vol 74 (3) ◽  
pp. 758-763 ◽  
Author(s):  
N. Al-Zoreky ◽  
J.W. Ayres ◽  
W.E. Sandine

Author(s):  
Divya Gupta ◽  
Mukesh Kumar ◽  
Vishal Gupta

Objective: To investigate the solvent-dependent antimicrobial activity and phytochemical analysis of extracts of Euphorbia hirta (leaves and flowers) and Murraya koenigii (leaves), as well as to evaluate the synergistic activity of these medicinal extracts with suitable antibiotic discs and antibiotics susceptibility of selected pathogenic microorganisms.Methods: The antimicrobial activity of the medicinal extracts was screened through agar well diffusion method and antibiotics susceptibility of selected microorganisms was investigated using disc diffusion method. A combined agar well diffusion and disc diffusion methods were used for the determination of synergistic activities of the extracts with antibiotic discs.Results: Among the different solvents, ethanol had maximum zone of inhibition against the test pathogens. Ethanolic leaf extracts of E. hirta exhibited the highest inhibitory activity against Candida albicans and Staphylococcus aureus with minimum inhibitory concentration value of 12.5 mg/mL and 25.0 mg/mL, respectively. Antimicrobial assay revealed that E. hirta extracts were active against all tested Gram-negative bacteria. However, none of the plant extracts had inhibitory activity against Gram-positive bacterium Propionibacterium acnes. Phytochemical screening for both the extracts from E. hirta revealed the presence of steroid, tannin, terpenoids, carbohydrates, alkaloid, flavonoid, diterpene, and glycoside, whereas M. koenigii extract was rich in saponins, protein, steroid, tannin, carbohydrates, alkaloid, flavonoid, and glycoside.Conclusion: The present study proposes that E. hirta and M. koenigii extracts are excellent sources of natural bioactive compounds that could be used as potent antimicrobial drugs to counter the emerging problem of antibiotic resistance of pathogenic microorganisms.


2020 ◽  
Vol 8 (6) ◽  
pp. 188-195
Author(s):  
Titik Taufikurohmah ◽  
Fadlilah Gita Shalli ◽  
Suyatno ◽  
Eka Apriyosa

Background: Alum has many functions in various fields such as an astringent substance has the potential to inhibit the growth of microorganisms. This study aims to know the antifungal and antibacterial activity against C.albicans and N.gonorrheae which can be used as medicine preparation for vaginal discharge. These microbes are pathogenic microorganisms commonly found in the vagina. Method: The method used is the disk diffusion which is based on a clear zone area to determine the inhibition. Variation concentration of alum used is 2.5; 5; 10; 15; 20 and 25%. Results: The results showed that alum has antimicrobial activity against pathogenic microbes, namely C.albicans and N.gonorrhea. This is indicated by the presence of clear zones formed in the area of paper disks. Concentrations of 20% and 25% have moderate antimicrobial activity. An increase in concentration in alum shows that the diameter of the clear zone that is formed is also getting bigger. Conclusions: In this study, it can be concluded that alum is proven to have antifungal and antibacterial activity against pathogenic microbes that live in the vagina. So, it has the potential to become one of the medicine compositions for vaginal discharge.


Materials ◽  
2019 ◽  
Vol 12 (18) ◽  
pp. 3020 ◽  
Author(s):  
Paula Bosch ◽  
Desislava Staneva ◽  
Evgenia Vasileva-Tonkova ◽  
Petar Grozdanov ◽  
Ivanka Nikolova ◽  
...  

A second-generation poly(propylene imine) dendrimer modified with acridine and its Cu(II) complex have been synthesized for the first time. It has been found that two copper ions form complexes with the nitrogen atoms of the dendrimeric core by coordinate bonds. The new compounds have been characterized by nuclear magnetic resonance (NMR), electron paramagnetic resonance (EPR), fourier-transform infrared spectroscopy (FTIR) and fluorescence spectroscopy. The spectral characteristics of the modified dendrimer have been measured in different organic solvents, and a negative fluorescence solvatochromism has been observed. The antimicrobial activity of the dendrimers has been tested against model pathogenic microorganisms in agar and by broth dilution method. The cotton fabric treated with both dendrimers has been evaluated towards pathogenic microorganisms. The obtained modified cotton fabrics have been shown to hamper bacterial growth and to prevent biofilm formation. Dendrimer cytotoxicity has been investigated in vitro in the model HEp-2 cell line.


Our Nature ◽  
1970 ◽  
Vol 7 (1) ◽  
pp. 139-145 ◽  
Author(s):  
P.P. Baruah ◽  
B. Kakati ◽  
I. Ahmed

The present paper deals with the morpho-taxonomic account of some hitherto unknown fresh water algal species of hydrocarbon polluted refinery drains of Assam. Twenty two taxa of class Chlorophyceae, Bacillariophyceae, Euglenineae and Cyanophyceae were identified from three effluent drains of Guwahati Oil Refinery. Cyanophyceae with 11 species was the dominant algal group in the study sites and Oscillatoria was the dominant genus with 8 species.Key words: Fresh water algae, Oscillatoria, oil refinery effluent, AssamDOI: 10.3126/on.v7i1.2561Our Nature (2009) 7:139-145 


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