scholarly journals Endocrine Disruption and Reproductive Disorders:Impacts onSexually Dimorphic Neuroendocrine Pathways

Reproduction ◽  
2021 ◽  
Author(s):  
Heather B Patisaul
Keyword(s):  
Reproductive Health ◽  
Semen Quality ◽  
Endocrine Disrupting Compounds ◽  
Reproductive Organs ◽  
Gonadal Hormones ◽  
Hpg Axis ◽  
Vertebrate Brain ◽  
Brain Sexual Differentiation ◽  
Human Reproductive ◽  
And Function

We are all living with hundreds of anthropogenic chemicals in our bodies every day, a situation that threatens the reproductive health of present and future generations. This review focuses on endocrine disrupting compounds (EDCs), both naturally occurring and man-made, and summarizes how they interfere with the neuroendocrine system to adversely impact pregnancy outcomes, semen quality, age at puberty, and other aspects of human reproductive health. While obvious malformations of the genitals and other reproductive organs are a clear sign of adverse reproductive health outcomes, injury to brain sexual differentiation and thus the hypothalamic-pituitary-gonadal (HPG) axis can be much more difficult to discern, particularly in humans. It is well-established that, over the course of development, gonadal hormones shape the vertebrate brain such that sex specific reproductive physiology and behaviors emerge. Decades of work in neuroendocrinology has elucidated many of the discrete and often very short developmental windows across pre- and postnatal development in which this occurs. This has allowed toxicologists to probe how EDC exposures in these critical windows can permanently alter the structure and function of the HPG axis. Included in this review are discussion of key EDC principles including how latency between exposure and the emergence of consequential health effects can be long, along with a summary of the most common and less well understood EDC modes of action. Also provided are extensive examples of how EDCs are impacting human reproductive health, and evidence that they have the potential for multi-generational physiological and behavioral effects.

Human Adult Reproductive System

2017 ◽  
Author(s):  
Patrick Guthrie ◽  
Johanna Von Hofe ◽  
Rachael B Lancaster
Keyword(s):  
Reproductive System ◽  
Endocrine System ◽  
Reproductive Organs ◽  
Anatomy And Physiology ◽  
Human Reproductive ◽  
Reproductive Anatomy ◽  
Males And Females ◽  
And Function ◽  
Pituitary Adrenal Axis ◽  
Physiologic System

The human reproductive system is a unique combination of organs and endocrine components that is extremely complex and adaptive. The reproductive organs are distinct between males and females, and sexual differentiation is a result of genotype, gonadal type, and phenotype. The anatomic and physiologic system of each sex is composed with a set purpose: to propagate the human species. Linked closely to the reproductive system is the endocrine system, which provides the messengers and feedback mechanisms that allow the development, maintenance, and function of the reproductive organs. The gonads have both endocrine and exocrine functions, namely steroidogenesis and gametogenesis. This review focuses on the components of the endocrine system as well as male and female anatomy and physiology to fully grasp the human reproductive system.  Key words: fertility, hypothalamic-pituitary-adrenal axis, reproductive anatomy, sexual aging, sexual physiology

scholarly journals PERBEDAAN EFEK IMPLEMENTASI BOOKLET DAN MANEKIN PADA PENYULUHAN KEBUTUHAN PERSONAL HIGIENE GENETALIA DI SDN RONOWIJAYAN KABUPATEN PONOROGO JAWA TIMUR

2020 ◽  
Vol 8 (2) ◽  
pp. 185
Author(s):  
Inna Sholicha Fitriani ◽  
Fetty Rosyadia
Keyword(s):  
Elementary School ◽  
Reproductive Health ◽  
Young Women ◽  
Reproductive Organs ◽  
Family Approach ◽  
Normality Test ◽  
Human Reproductive ◽  
Study Population ◽  
Approach Method ◽  
The Right

Adolescence is a period of maturity of human reproductive organs. Candidiasis 25 % - 50 %, vaginitis 20% - 40% and trichomoniasis 5% - 15%. Every teenager must have the right and proper information about reproductive health aspects such as how to maintain the health of reproductive organs, and be able to practice the behavior of maintaining healthy and responsible reproductive organs to avoid diseases that might attack their reproductive organs. This study aims to identify the differences in the effects of the implementation of booklets and mannequins on counseling the personal needs of genetalia hygiene in young women at Ronowijayan Ponorogo Elementary School. This study used an experimental method with a type of randomized experimental study. The research location was the SDN Ronowijayan Siman Ponorogo period of study starting in February December 2018. The study population used was all young women at Ronowijayan Ponorogo Elementary School with a study sample aged 10 untill 12 years at Ronowijayan Ponorogo Elementary School. The results of the data were analyzed using the T test (α = 5%) with the normality test of the distribution using Shapiro-Wilk. The results of the study were 0.896> 0.05 (95% confidence), so there was no difference in effect between before treatment and after treatment of the implementation of the booklet with the implementation of manikin. It is necessary to introduce reproductive health with a family approach method for young women with the hope that the achievement of reproductive health education can be achieved optimally.

scholarly journals The Effects of E-Cigarette Vapor Components on the Morphology and Function of the Male and Female Reproductive Systems: A Systematic Review

2020 ◽  
Vol 17 (17) ◽  
pp. 6152
Author(s):  
Kamila Szumilas ◽  
Paweł Szumilas ◽  
Anna Grzywacz ◽  
Aleksandra Wilk
Keyword(s):  
Animal Studies ◽  
Reproductive Organs ◽  
Limited Evidence ◽  
Reproductive Systems ◽  
Male And Female ◽  
Quit Smoking ◽  
Hormonal Balance ◽  
Human Reproductive ◽  
And Function ◽  
Female Reproductive Organs

E-cigarettes, a comparatively new phenomenon, are regarded as a safer alternative to conventional cigarettes. They are increasingly popular among adolescents of both sexes, and many smokers use e-cigarettes in their attempts to quit smoking. There is little understanding of the effects of exposure to e-cigarette vapors on human reproductive health, human development, or the functioning of the organs of the male and female reproductive systems. Data on the effects of the exposure were derived mainly from animal studies, and they show that e-cigarettes can affect fertility. Here, we review recent studies on the effects of exposure to e-cigarettes on facets of morphology and function in the male and female reproductive organs. E-cigarettes, even those which are nicotine-free, contain many harmful substances, including endocrine disruptors, which disturb hormonal balance and morphology and the function of the reproductive organs. E-cigarettes cannot be considered a completely healthy alternative to smoking. As is true for smoking, deleterious effects on the human reproductive system from vaping are likely, from the limited evidence to date.

Human Adult Reproductive System

2017 ◽  
Author(s):  
Patrick Guthrie ◽  
Johanna Von Hofe ◽  
Rachael B Lancaster
Keyword(s):  
Reproductive System ◽  
Endocrine System ◽  
Reproductive Organs ◽  
Anatomy And Physiology ◽  
Human Reproductive ◽  
Reproductive Anatomy ◽  
Males And Females ◽  
And Function ◽  
Pituitary Adrenal Axis ◽  
Physiologic System

The human reproductive system is a unique combination of organs and endocrine components that is extremely complex and adaptive. The reproductive organs are distinct between males and females, and sexual differentiation is a result of genotype, gonadal type, and phenotype. The anatomic and physiologic system of each sex is composed with a set purpose: to propagate the human species. Linked closely to the reproductive system is the endocrine system, which provides the messengers and feedback mechanisms that allow the development, maintenance, and function of the reproductive organs. The gonads have both endocrine and exocrine functions, namely steroidogenesis and gametogenesis. This review focuses on the components of the endocrine system as well as male and female anatomy and physiology to fully grasp the human reproductive system.  Key words: fertility, hypothalamic-pituitary-adrenal axis, reproductive anatomy, sexual aging, sexual physiology

Do environmental estrogens contribute to the decline in male reproductive health?

1995 ◽  
Vol 41 (12) ◽  
pp. 1896-1901 ◽  
Author(s):  
T K Jensen ◽  
J Toppari ◽  
N Keiding ◽  
N E Skakkebaek
Keyword(s):  
World War Ii ◽  
Reproductive Health ◽  
Fetal Development ◽  
Semen Quality ◽  
World War ◽  
Past Half Century ◽  
Endocrine Disrupting ◽  
Common Etiology ◽  
And Function ◽  
Male Reproductive Health

Abstract Several observations suggest that male reproductive health has been declining since World War II in many countries. The incidence of testicular cancer, hypospadias, and cryptorchidism has been increasing and semen quality has been decreasing, and these may have a common etiology. Treatment of several million pregnant women with the synthetic estrogen diethylstilbestrol led to an increase in these conditions among the sons of these women. These abnormalities probably arise during fetal development. The similarity between these effects and the adverse change in male reproductive development and function raised the question of whether the adverse changes are attributable to altered exposures to estrogenic and other endocrine-disrupting agents during fetal development. We speculate that alteration in exposure to estrogen in the past half-century may have caused the changes in male reproductive health.

scholarly journals Spring Freeze Damage of Pecan Bloom: A Review

Horticulturae ◽  
2020 ◽  
Vol 6 (4) ◽  
pp. 82
Author(s):  
Amandeep Kaur ◽  
Louise Ferguson ◽  
Niels Maness ◽  
Becky Carroll ◽  
William Reid ◽  
...  
Keyword(s):  
Tree Height ◽  
The United States ◽  
Reproductive Organs ◽  
Tree Age ◽  
The Us ◽  
Nut Production ◽  
Freeze Damage ◽  
Terminal Buds ◽  
And Function ◽  
The Impact

Pecan is native to the United States. The US is the world’s largest pecan producer with an average yearly production of 250 to 300 million pounds; 80 percent of the world’s supply. Georgia, New Mexico, Texas, Arizona, Oklahoma, California, Louisiana, and Florida are the major US pecan producing states. Pecan trees frequently suffer from spring freeze at bud break and bloom as the buds are quite sensitive to freeze damage. This leads to poor flower and nut production. This review focuses on the impact of spring freeze during bud differentiation and flower development. Spring freeze kills the primary terminal buds, the pecan tree has a second chance for growth and flowering through secondary buds. Unfortunately, secondary buds have less bloom potential than primary buds and nut yield is reduced. Spring freeze damage depends on severity of the freeze, bud growth stage, cultivar type and tree age, tree height and tree vigor. This review discusses the impact of temperature on structure and function of male and female reproductive organs. It also summarizes carbohydrate relations as another factor that may play an important role in spring growth and transition of primary and secondary buds to flowers.

Comparative effects of Orchis anatolica vs. the red Korean Panax ginseng treatments on testicular structure and function of adult male mice

2015 ◽  
Vol 12 (1) ◽  
Author(s):  
Nabil A. Khouri ◽  
Haytham M. Daradka ◽  
Mohammed Z. Allouh ◽  
Ahmad S. Alkofahi
Keyword(s):  
Panax Ginseng ◽  
Male Fertility ◽  
Virgin Female ◽  
Reproductive Organs ◽  
Serum Markers ◽  
Structure And Function ◽  
Control Group ◽  
Male Mice ◽  
Fertility Potential ◽  
And Function

Abstract: The effects of: Both plants were administered orally to two separate mice groups at a dose of 800 mg/kg/day for 35 days and compared with control group. After treatment, 5 mice of each group were sacrificed and total mice weights, reproductive organs’ weights, spermatogenesis, and androgenic serum markers were investigated. The remaining mice from all groups were allowed to mate with virgin female mice to explore male fertility potential.: Results indicated that body and organs’ weights were increased significantly in mice treated with: We can conclude that

scholarly journals Zinc: A Necessary Ion for Mammalian Sperm Fertilization Competency

2018 ◽  
Vol 19 (12) ◽  
pp. 4097 ◽  
Author(s):  
Karl Kerns ◽  
Michal Zigo ◽  
Peter Sutovsky
Keyword(s):  
Male Fertility ◽  
Reproductive Tract ◽  
Zinc Supplementation ◽  
Female Reproductive Tract ◽  
Sperm Maturation ◽  
Cellular Mechanisms ◽  
Human Reproductive ◽  
Semen Processing ◽  
New Research ◽  
And Function

The importance of zinc for male fertility only emerged recently, being propelled in part by consumer interest in nutritional supplements containing ionic trace minerals. Here, we review the properties, biological roles and cellular mechanisms that are relevant to zinc function in the male reproductive system, survey available peer-reviewed data on nutritional zinc supplementation for fertility improvement in livestock animals and infertility therapy in men, and discuss the recently discovered signaling pathways involving zinc in sperm maturation and fertilization. Emphasis is on the zinc-interacting sperm proteome and its involvement in the regulation of sperm structure and function, from spermatogenesis and epididymal sperm maturation to sperm interactions with the female reproductive tract, capacitation, fertilization, and embryo development. Merits of dietary zinc supplementation and zinc inclusion into semen processing media are considered with livestock artificial insemination (AI) and human assisted reproductive therapy (ART) in mind. Collectively, the currently available data underline the importance of zinc ions for male fertility, which could be harnessed to improve human reproductive health and reproductive efficiency in agriculturally important livestock species. Further research will advance the field of sperm and fertilization biology, provide new research tools, and ultimately optimize semen processing procedures for human infertility therapy and livestock AI.

scholarly journals The 2nd URNCST Journal Case Abstract Competition: Human Reproductive Health and Environment

2019 ◽  
Vol 3 (2) ◽  
pp. A1-A5
Author(s):  
Molly HR Cowls ◽  
Jessica B Saini ◽  
Jeremy Y Ng
Keyword(s):  
Reproductive Health ◽  
Human Reproductive
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