scholarly journals Concise review: Medicinal plants are effective against leishmaniasis

2017 ◽  
Vol 4 (11) ◽  
pp. 1775
Author(s):  
Mahmoud Bahmani ◽  
Naser Abbasi ◽  
Masih Hosseini ◽  
Mahmoud Rafieian-Kopaei
Keyword(s):  
Medicinal Plants ◽  
Adverse Effects ◽  
Herbal Medicines ◽  
Pubmed Central ◽  
Pentavalent Antimony ◽  
Artemisia Aucheri ◽  
Tropical Areas ◽  
Review Study ◽  
Great Health ◽  
Natural Medicines

Leishmaniasis is an important zoonotic parasitic disease in tropical areas. It is a neglected disease and is a great health catastrophe in Iran. Pentavalent antimony compounds are used for its treatment, but they have adverse effects. Therefore, the use of natural herbs with low adverse effects seems necessary for treatment of Leishmaniasis. In this study, we tried to introduce the natural medicines effective against Leishmaniasis. In this review study, keywords searched included natural medicines, herbal medicines, medicinal plants, Leishmaniasis, and treatment in relevant publications published between 1990 and 2017. Searching was on databases including ISI Web of Science, PubMed, PubMed Central, Scopus, ISC, SID, Magiran and some other databases. The relevant articles were reviewed for the review study. The results showed that medicinal plants: Ferula assafoatida (with IC50 of 0.38 mg/ml), Glycyrrhiza glabra (with IC50 of 25mg/ml), Allium sativum (with IC50 of 0.57 mg/ml), Cephalis ipecacuana (with IC50 of 0.01 mg/ml), Artemisia aucheri (with IC50 of 0.46 mg/ml) and Eucalyptus globulus (with IC50 of 0.17 mg/ml) were the natural medicines effective against the disease. Compositions with di-, tri-, tetra-Sulfide, Coumarin derivatives, Camuou-nephrole, Episamarcandine, Amblipernine, Carnephrole, Azafoetidine, Froxolicin, Azafoetidinole, Saradaferine, 1, 8 Cineole, Scopodreniole, Semen, Sabinine, Cineole, Inaleole, Eojenole, Farenzole, Borneol, Allicin, acid Glycerisic, Emetine and Cephalin can have the potential to produce potent drugs against Leishmaniasis. In sum, there are some specific medicinal plants and compounds effective against Leishmaniasis which can be used per se or following changes in their formula to prepare and introduce new drags against this disease.

scholarly journals A review of available herbal medicine options for the treatment of chronic insomnia

2021 ◽  
Vol 15 (5) ◽  
pp. 1589-1598
Author(s):  
Z. Poursaleh ◽  
M. Khodadoost ◽  
E. Vahedi ◽  
M. M. A. Attari ◽  
M. Jafari ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Herbal Medicine ◽  
Adverse Effects ◽  
Randomized Clinical Trials ◽  
Herbal Medicines ◽  
Chronic Insomnia ◽  
Bioactive Metabolites ◽  
Additional Information ◽  
Sedative Activity ◽  
Natural Medicines

Background: Insomnia is a universal health problem that affects the health and quality of life of people worldwide. During the last decade treatment of insomnia with herbal has been introduced to be effective but unfortunately, the safety and efficacy of these medicines are currently uncertain. However, the administration of various herbal medicines for insomnia is increasing mainly due to the diversity of various adverse effects of western medication. Objective: The present study is aimed to investigate available herbal medicine options for the treatment of chronic insomnia. Method: All demanded data were retrieved from electronic databases, Natural Medicines, TCMID, Natural Medicines Comprehensive Database, MedlinePlus, PubMed, EMBASE, and Google Scholar. Among them, randomized clinical trials were chosen precisely to be investigated more for seeking any additional information related to the treatment of chronic insomnia. All related papers in English and Persian languages included in the study criteria. At first, 162 articles were chosen to be investigated, then after screening all articles based on the PRISMA method, 83 qualified articles remained to be investigated carefully. Results: Herbal plants with medical properties as sedative agents are obtaining more and more attention because they contain various types of natural bioactive metabolites with the lowest rate of adverse effects. Moreover, these novel medicines are highly economic, with high efficacy while could be available easily. Conclusion: The data from this study demonstrated that medical plants could yield sedative activity and some of them are effective for insomnia, but we must not forget that further clinical trials are demanded to approve this. Keywords: Sleep disorders, Chronic insomnia, Herbal medicine, Alternative medication, Treatment.

Herbal Products for Common Auto-Inflammatory Disorders - Novel Approaches

2018 ◽  
Vol 21 (3) ◽  
pp. 161-174 ◽  
Author(s):  
Shanoo Suroowan ◽  
Fawzi Mahomoodally
Keyword(s):  
Adverse Effects ◽  
Chronic Conditions ◽  
Herbal Medicines ◽  
Review Article ◽  
Herbal Products ◽  
Inflammatory Disorders ◽  
Treatment Regimens ◽  
Synthetic Agents ◽  
Unique Approach ◽  
Novel Approaches

Background: Common auto-inflammatory disorders (CAIDs) constitute a wide array of ailments ranging from acute allergies to chronic conditions. Globally, CAIDs remain one of the leading causes of disability and morbidity. Despite playing a leading therapeutic role, the vast profusion of anti-inflammatory synthetic agents have not been able to fully resolve a panoply of CAIDs. Additionally, contemporary synthetic therapy approaches remain bounded by a wide array of limitations essentially being adverse effects and unaffordable costs. In this advent, the use of herbal products provides an interesting avenue to explore in view of developing such treatment regimens. Objective: This review article endeavors to highlight potential herbal products and isolated phytochemicals which can be of benefit in the prophylaxis, management, and treatment alongside avoiding the relapse of CAIDs. Conclusion: This review article has highlighted that herbals, herbal products, and isolated metabolites hold a huge potential in the prophylaxis, management, and treatment of CAIDs. Herbals can act on various targets involved in the pathogenesis of inflammatory disorders. In addition, novel approaches for the management of CAIDs are numerous. Indeed, nanoparticles loaded with phytochemicals have been developed to specifically target the colon for IBD treatment. In silico approaches using herbals also offer unlimited avenues to decipher new pharmacophores. Investigating the potential of polyherbal formulations is another unique approach which can be investigated. Given the inefficacy of conventional medicines, the concomitant use of conventional and herbal medicines can also be explored.

Natural Phytochemicals and Their Therapeutic Role in Management of Several Diseases: A Review

2020 ◽  
Vol 6 (1) ◽  
pp. 43-53 ◽  
Author(s):  
Nitin R. Shirsath ◽  
Ajaygiri K. Goswami
Keyword(s):  
Side Effects ◽  
Low Cost ◽  
Herbal Medicines ◽  
Biological Source ◽  
Natural Medicine ◽  
Synthetic Chemicals ◽  
Alternative Approach ◽  
Health Related ◽  
Activity Mechanism ◽  
Natural Medicines

Introduction: These days, a lot of people face some health-related problems in day to day life. The conventional synthetic medicine is not effective enough to cure them alone. The conventional therapy for the management of these health-related issues involves the use of hazardous synthetic chemicals and surgical diagnosis, which have lots of serious side effects. It is necessary to conduct research on herbal medicines, this is an alternative approach to avoid the side effects of synthetic medicines to achieve high effectiveness, low cost and improve patient compliance. Methods: The present survey is an analysis of some of the available data on the use of plants with their biological source, active phytochemicals constituents and a probable activity/ mechanism of action of several classes of drugs. This work also focused on highlighting the advantages of natural medicines for maximum utilization. Results: This article aims to increase awareness about natural medicine and help people find a suitable herbal medicine for the treatment of specific diseases. Conclusion: This article also exhibits the scope for further process in the development of new natural substance for the management of several diseases.

Highlights on Important Medicinal Plants for the Menopause Syndrome

2021 ◽  
Vol 17 ◽  
Author(s):  
Rafaele de A. Rodrigues ◽  
Aline de S. Ramos ◽  
José Luiz P. Ferreira ◽  
Jefferson Rocha de A. Silva ◽  
Ana Clara B. Maria ◽  
...  
Keyword(s):  
Hormone Replacement Therapy ◽  
Medicinal Plants ◽  
Adverse Effects ◽  
Replacement Therapy ◽  
Trifolium Pratense ◽  
Hormone Replacement ◽  
Signs And Symptoms ◽  
Sufficient Information ◽  
Hormonal Changes ◽  
Artery Disease

Background: A reduction in ovarian hormones, which is distinctive of menopause, often involves signs and symptoms that compromise the quality of life and health of women. The transient manifestations are changes in the menstrual cycle, vasomotor symptoms, neuropsychological symptoms, and genitourinary changes. In some cases, the hormonal changes can evolve to non-transitory manifestations, which include urinary incontinence, changes in metabolism, osteoporosis and cardiovascular diseases. Hormone replacement therapy is the treatment of choice to alleviate transient symptoms of menopause; however, there are many limitations, contraindications and situations in which the risks of adverse effects are high, such as coronary artery disease, stroke, venous thromboembolism, dementia, type 2 diabetes, and the increased incidence of breast cancer. Objective: This work aims to highlight important medicinal plants for the treatment of the transient symptoms of menopause, with less side effects than traditional hormone replacement therapy. Results: There is sufficient information regarding the efficacy and safety in the use of the following plant species in the treatment of transient symptoms of menopause: Actaea racemosa, Glycine max, Trifolium pratense, Salvia officinalis, Humulus lupulus, Panax ginseng, Vitex agnus-castus, and Trigonella foenum-graecum. Additionally, the search indicated the chemical classes related to the benefits of the selected species, adverse effects, and interactions with other drugs.

Antiviral and Immunity-modulating Natural Herbs in the Prevention of COVID-19

2021 ◽  
pp. 81-94
Author(s):  
Sonali S Gadge
Keyword(s):  
Immune System ◽  
Medicinal Plants ◽  
Nigella Sativa ◽  
Curcuma Longa ◽  
Antiviral Drug ◽  
Herbal Medicines ◽  
Echinacea Purpurea ◽  
Black Pepper ◽  
Tinospora Cordifolia ◽  
Ocimum Sanctum

The COVID-19 has spread all over the world and there is no single drug or medicine for the prevention and the treatment of this deadly disease. One can get prevention from this disease by boosting the immune system. Persons with weak immune system e.g. children, elder patients or patients with preexisting diseases affect rapidly due to coronavirus. This novel coronavirus attacks mainly on the person immunity. For the centuries the herbal medicinal plants have many beneficial effects against deadly viruses. Herbal medicines provide a rich resource for new antiviral drug development. These natural agents interact with the life cycle of virus such as virus entry, replication, assembly and release. In this review, the importance, immunomodulator, antiviral and pharmacological activities of some medicinal plants, namely, Allium Sativum, Zingiber Officinalis, Cinnamomum zeylanicum, Curcuma longa, Ocimum sanctum, Glycyrrhiza glabra, Ginseng, Black pepper, Emblica officinalis, Withania somnifera, Tinospora cordifolia, Echinacea purpurea, Azadirachta indica, Piper betel, Eugenia caryophyllata, Cinchona calisaya, Nigella sativa, Cuminum cyminum are highlighted. These medicinal plants have many phytoconstituents like alkaloids, glycosides, terpenoids, flavonoids, lactones, polysaccharides, volatile oils, tannins, resins, etc which are helpful for boosting immunity and will help in the prevention and in the management of COVID-19. Several types of research attempted to use herbal medicines against COVID-19.

scholarly journals The Phytochemistry of Cherokee Aromatic Medicinal Plants

Medicines ◽  
2018 ◽  
Vol 5 (4) ◽  
pp. 121 ◽  
Author(s):  
William Setzer
Keyword(s):  
Native Americans ◽  
Medicinal Plants ◽  
Biological Activities ◽  
Herbal Medicines ◽  
Black Cohosh ◽  
Cimicifuga Racemosa ◽  
Traditional Uses ◽  
Aromatic And Medicinal Plants ◽  
Phytochemical Investigation ◽  
Phytochemical Constituents

Background: Native Americans have had a rich ethnobotanical heritage for treating diseases, ailments, and injuries. Cherokee traditional medicine has provided numerous aromatic and medicinal plants that not only were used by the Cherokee people, but were also adopted for use by European settlers in North America. Methods: The aim of this review was to examine the Cherokee ethnobotanical literature and the published phytochemical investigations on Cherokee medicinal plants and to correlate phytochemical constituents with traditional uses and biological activities. Results: Several Cherokee medicinal plants are still in use today as herbal medicines, including, for example, yarrow (Achillea millefolium), black cohosh (Cimicifuga racemosa), American ginseng (Panax quinquefolius), and blue skullcap (Scutellaria lateriflora). This review presents a summary of the traditional uses, phytochemical constituents, and biological activities of Cherokee aromatic and medicinal plants. Conclusions: The list is not complete, however, as there is still much work needed in phytochemical investigation and pharmacological evaluation of many traditional herbal medicines.

scholarly journals SOME ETHNO-MEDICINAL PLANTS AND ECO-FRIENDLY NATURAL COLORS YIELDING FLOWERING PLANTS OF B.S.N. GOVT. P.G. COLLEGE CAMPUS, SHAJAPUR (M.P.) – A SURVEY REPORT

2015 ◽  
Vol 3 (4) ◽  
pp. 1-6
Author(s):  
BodaneArun Kumar
Keyword(s):  
Natural Products ◽  
Medicinal Plants ◽  
Herbal Medicines ◽  
Flowering Plants ◽  
College Campus ◽  
Medicinal Uses ◽  
Survey Report

The present work is attempt has been made to compile the some ethno-medicinal plants and eco-friendly natural colors yielding flowering plants their preparations used for cure of diseases and information of flowering plants with the list of plants from B.S.N. Govt. P.G. College campus Shajapur, India. The present study focused on some important plants having medicinal uses and color yielding potential. Now-a-days natural products and herbal medicines have been recommended for the treatment of various diseases. The present study of ethno-medicinal and natural colors yielding flowering plants is helpful for local peoples of Shajapur.

scholarly journals Ethno Botanical Studies of District Dera Ghazi Khan, Province Punjab, Pakistan

2020 ◽  
Author(s):  
Tahira Aziz Mughal ◽  
Hamna Yasin ◽  
Zubaida Yousaf ◽  
Ismat Naeem Naeem
Keyword(s):  
Medicinal Plants ◽  
Rural Areas ◽  
Neurological Diseases ◽  
Herbal Medicines ◽  
Climatic Conditions ◽  
Structured Interviews ◽  
Medicinal Uses ◽  
Plant Parts ◽  
Floral Diversity ◽  
Natural Drugs

Abstract Background The chief aim of this study was to enlist the Ethnobotanical uses of plants in Dera Ghazi Khan, Punjab, Pakistan. Due to unique geographical and climatic conditions, Pakistan has a great floral diversity. Plants have been used by the indigenous people for treatment of different ailments since long. They are still dependent on the plants for their domestic purposes. Moreover, plants are used as first aid to treat diverse ailments such as hepatic disorders, cardiac diseases, neurological diseases, anticancer, respiratory diseases, ENT problems, gynecological problems etc. The traditional uses of medicinal plants lead to the discovery of natural drugs. This is first quantitative ethno medicinal documentation of medicinal plants in Dera Ghazi Khan. Punjab, Pakistan. Methods This ethno botanical information was collected from about 200 informants including male and female. Sample size was determined by statistical formula. The informative data was based on semi-structured interviews, group discussions, Questionnaire and field visits. Then the data was analyzed by applying different quantitative indices such as Informant Consent Factor (ICF), Use value (UV), Relative Frequency of Citation (RFC) and the Fidelity level (FL). Results Almost 185 plants belonging to 52 families were reported. Most-frequently cited families were Astreaceae (20 species) and Solanaceae (10 species). The most dominant life form was herbs (51%). The most-used plant parts were leaves (68%), followed by whole plant (65%), Most common mode of administration is extraction (50%). Generally herbal medicines were acquired from fresh plant material. Many species were reported with their different medicinal uses as has been reported in literature. Conclusions This ethno botanical documentation revealed that the plants are still used by natives of rural areas in their day-to-day lives. This study provides basis for the conservation of local flora. Plants with high ICF, UV and FL can be further used for phytochemical and pharmacological studies. This documentation could provide baseline information which can be used to develop new plant-based commercial drugs.

scholarly journals PRELIMINARY STUDY ON SOME MEDICINAL HERBS AND SHRUBS OF DISTRICT SOLAN (HP)

2021 ◽  
Vol p5 (6) ◽  
pp. 3101-3108
Author(s):  
Pathania Singh Mamta ◽  
Bhardwaj Payal ◽  
Pathania Singh Dhirendra
Keyword(s):  
Medicinal Plants ◽  
Herbal Medicines ◽  
Intimate Relationship ◽  
Daily Lives ◽  
Tribal People ◽  
Birth Attendants ◽  
Living Tradition ◽  
Medicinal Use ◽  
Medicinal Properties ◽  
Preliminary Study

Herbal medicines are in practice since time immortal. India has probably the oldest, richest and most diverse cul- tural traditions within the use of medicinal plants. Indians 3500 BC, Chinese 3000 BC and Egyptians 2500 BC knew the properties of medicinal plants. Medicinal plants' use is still a living tradition. This is supported by the fact that there exists around a million traditional, village-based carriers of herbal medicine traditions in the form of traditional birth attendants, visha voids, bonesetters, herbal healers and wandering monks. Tribal people who live in harmony with nature and the environment share an intimate relationship with the plants. Beneficial medicinal properties of plants have been used in some forms or the other by these tribal people and cures were effective without any harmful side effects. The medicinal plants come from categories of shrubs, herbs and trees. Various parts of these plants which are used include fruits, roots, leaves, flowers, seeds, extract etc. and are of immense use to mankind; they are a part of our daily lives, making us wealthy with the world's greatest treasure- Health. Medic- inal plants have served humankind, for hundreds of years and still, these plants are used traditionally to cure vari- ous diseases. Some of the selected plants of district Solan were analyzed for their medicinal use with the help of information gathered from local people. Keywords: Medicinal plants, Herbal medicines, shrubs, Solan

scholarly journals An Overview of the Various Uses of Ephedra distachyaL. from the Past to the Present

2020 ◽  
Vol 1 (2) ◽  
pp. 82-86
Author(s):  
Mansureh Ghavam ◽  
Zeinab Soleimaninejad
Keyword(s):  
Medicinal Plants ◽  
Traditional Medicine ◽  
Scientific Evidence ◽  
Experimental Studies ◽  
Trial And Error ◽  
Traditional Medicines ◽  
Beneficial Effects ◽  
Ephedra Distachya ◽  
Ancient Times ◽  
Review Study

Background: Nowadays, many people believe in traditional medicines and use them for different diseases. Knowledge of medicinal plants and traditional medicine has been practiced for centuries through trial and error, and many important treatments for the disease have been passed down from one generation to the next. Ephedra is a valuable plant and has been used to treat diseases since ancient times. Accordingly, this study aims to comprehensively introduce Ephedra distachya L. in traditional medicine. Methods: In this review study, databases such as Google Scholar, SID, Scopus, and books on medicinal plants in Persian and English languages were searched to collect data. The keywords included "ephedra", "traditional medicine", "goat’s beard", and "medicinal plants". Results: Many resources highlighted the importance of using ephedra due to its useful properties. Experimental studies in traditional medicine show the effect of this plant in the prevention of diseases, such as asthma and bronchitis. Conclusion: Considering the beneficial effects of ephedra and scientific evidence about its effects, further studies are needed to better understand the use of this plant in traditional medicine.

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