scholarly journals A pandémia hatása a személyes kapcsolathálózati struktúrára.

2021 ◽  
Vol 2 (3) ◽  
pp. 350-357
Keyword(s):  
Social Isolation ◽  
The Other ◽  
Three Dimensions ◽  
Office Workers ◽  
Human Relations ◽  
Home Office ◽  
Face To Face ◽  
Other Hand ◽  
Working From Home ◽  
Significant Difference

Összefoglaló. Jelen írásban a biztonság három dimenziójának (egészség, munka, emberi kapcsolatok) összefüggésében a home office pozitív és negatív jellemzőit vizsgáljuk meg a pandémiás időszakban. Tanulmányunk egy 2020 májusában, reprezentatív mintán lekérdezett felmérés adataira épül, mely a vírushelyzetre vonatkozó kérdéseket és egy kapcsolati naplót tartalmazott. Az eredmények alapján a home office-ban dolgozók kevésbé voltak kitéve a fertőzésveszélynek: kevesebb időt töltöttek saját otthonukon kívül és tömegközlekedést is kevésbé használtak. Másrészt az otthonról dolgozók átlagosan kevesebb emberrel is találkoztak személyesen. A találkozásokban mutatkozó különbséget ugyanakkor kifejezetten a munkatársi kapcsolatok magyarázzák, míg a családi és baráti kapcsolataik megvédték az otthonról dolgozókat a társas izoláció veszélyétől. Summary. The emergence of the Covid-19 virus in spring 2020 has significantly transformed the daily lives of the population. One of the major changes affecting the world of work is that many people have been able to work remotely from home. In this paper, we focus on the home office phenomenon with regard to the three dimensions of security (health, work and human relations) and examine its positive and negative impacts in the context of human relations during the pandemic. It is assumed that home office is more secure against the virus, as those working from home may choose not to leave their homes at all and thus protect themselves from the virus by being physically isolated. On the other hand, it is also assumed that home office workers encounter fewer people than non-home office workers and are therefore more vulnerable to social isolation. In our study, we compare the characteristics of these two groups using descriptive statistics based on data from a national representative sample of 1,001 people contacted by telephone in May 2020. The survey included questions on the pandemic situation on the one hand, and a so-called contact diary on the other hand, in which respondents were asked to name all persons (and their characteristics) with whom they had spoken on that day beyond saying hello. First, the results show that home office workers were indeed less exposed to the risk of infection, as they spent significantly less time away from home, used public transport less, and none of them were abroad. Second, our data also show that there is a significant difference in the number of face-to-face encounters between home and non-home workers. Home office workers met on average two people face-to-face on the day of the survey, while non-home office workers met on average five people. While no significant difference was found in the number of relatives – whether or not they lived under the same roof as the respondent – between home office workers and those who went to work, the number of encounters with non-relatives was significantly higher among non-home office workers. The difference was mainly due to workplace contacts. This suggests that those working from home were protected from the risk of social isolation by their emotionally and physically close relationships. These results further support the finding that, in a crisis situation, the security provided by family ties is particularly valued and strong bonds are essential for the individual.

Effectiveness of Virtual Resilience Training on Assertiveness in Student Girls Aged 9–10 Years: A 1-Month Follow-Up

2021 ◽  
pp. 105984052110135
Author(s):  
Shima Gadari ◽  
Jamile Farokhzadian ◽  
Parvin Mangolian Shahrbabaki
Keyword(s):  
Experimental Study ◽  
Internal Stress ◽  
Intervention Group ◽  
The Other ◽  
Hormonal Changes ◽  
Emotional Instability ◽  
Other Hand ◽  
Significant Difference ◽  
Resilience Training

Girls between the ages of 9 and 10 begin to experience physical, physiological, and hormonal changes that may lead to internal stress. At this age, children are struggling for autonomy; on the other hand, they may experience emotional instability, and for these reasons, they may be vulnerable in many ways. This experimental study aimed to investigate the effect of resilience training on assertiveness in student girls aged 9–10. Data were collected before, immediately after, and 1 month after the intervention in the control ( n = 40) and intervention ( n = 37) groups. There was a significant difference between the assertiveness of the intervention immediately (26.80 ± 3.73) and 1 month after the intervention (27.05 ± 3.73), and assertiveness significantly increased in the intervention group ( p = .0001). Resilience training leads to improvements in assertiveness in student girls aged 9–10.

scholarly journals The Effect of Geogebra on Students’ Conceptual and Procedural Knowledge: The Case of Applications of Derivative

2017 ◽  
Vol 7 (2) ◽  
pp. 67 ◽  
Author(s):  
Mehmet Fatih Ocal
Keyword(s):  
Conceptual Knowledge ◽  
Teaching And Learning ◽  
Procedural Knowledge ◽  
Dynamic Geometry ◽  
The Other ◽  
Control Group ◽  
Other Hand ◽  
Significant Difference ◽  
Before And After ◽  
Post Test

Integrating the properties of computer algebra systems and dynamic geometry environments, Geogebra became an effective and powerful tool for teaching and learning mathematics. One of the reasons that teachers use Geogebra in mathematics classrooms is to make students learn mathematics meaningfully and conceptually. From this perspective, the purpose of this study was to investigate whether instruction with Geogebra has effect on students’ achievements regarding their conceptual and procedural knowledge on the applications of derivative subject. This study adopted the quantitative approach with pre-test post-test control group true experimental design. The participants were composed of two calculus classrooms involving 31 and 24 students, respectively. The experimental group with 31 students received instruction with Geogebra while the control group received traditional instruction in learning the applications of derivative. Independent samples t-test was used in the analysis of the data gathered from students’ responses to Applications of Derivative Test which was subjected to them before and after teaching processes. The findings indicated that instruction with Geogebra had positive effect on students’ scores regarding conceptual knowledge and their overall scores. On the other hand, there was no significant difference between experimental and control group students’ scores regarding procedural knowledge. It could be concluded that students in both groups were focused on procedural knowledge to be successful in learning calculus subjects including applications of derivative in both groups. On the other hand, instruction with Geogebra supported students’ learning these subjects meaningfully and conceptually.

scholarly journals Consequences of COVID-19 on my experiment of gene overexpression in beans

2021 ◽  
Vol 39 (4) ◽  
Author(s):  
Salma Sarai González-Meléndez
Keyword(s):  
Subcellular Location ◽  
Confocal Microscope ◽  
The Other ◽  
Research Center ◽  
Gene Overexpression ◽  
Research Centers ◽  
Experimental Phase ◽  
Face To Face ◽  
Other Hand ◽  
At Home

<p>My name is Salma Meléndez and I am currently a graduate in Agrogenomic Sciences. In March 2020, when COVID-19 was detected in Mexico, I was in my eighth semester of my undergraduate degree. At that time, he had an experiment of overexpression of a gene in bean roots, in order to explore its function during symbiosis with rhizobial bacteria. Unfortunately, the laboratory and the entire campus canceled their face-to-face activities in order to reduce the risk of contagion. An alternative was to take the experimental plants to my house to give the proper care, however, the situation became difficult as I did not have the space or the required conditions at home. On the other hand, other research centers with which we had collaboration agreements also canceled access, such is the case of the Optical Research Center, where we used the confocal microscope to detect subcellular location of proteins. The closure of institutions allowed me to write theoretical parts of my thesis, however, the experimental phase was definitely affected for at least six months. The experiment with the plants was almost completely lost. In the subsequent months I had the opportunity to re-enter my institution; however, under strict conditions and on staggered days, which made certain measurements that require daily continuity difficult. Currently, the laboratory is not as it used to look, full of colleagues sharing results and difficulties, exchanging advice and even certain materials. I think the pandemic has pushed us to do our work more individually and slowly. Consequently, my degree was delayed and transferred from 2020 to 2021. There are still many challenges to overcome, although activities have not been fully restored, science does not stop and we have found a way to face it, slowly but surely.</p>

scholarly journals Configuraciones tonales de frases entonativas en enunciados aseverativos del español de la Ciudad de México

2020 ◽  
Vol 8 (2) ◽  
pp. 117-141
Author(s):  
Alberto Rodríguez Márquez
Keyword(s):  
Social Networks ◽  
Spontaneous Speech ◽  
The Other ◽  
Prosodic Features ◽  
Speech Corpus ◽  
Data Set ◽  
Other Hand ◽  
Significant Difference ◽  
Speech Data ◽  
Intonational Phrases

The objective of this paper is to describe the prosodic features of the final intonation contour of minor intonational phrases (ip) and the tonemes of major intonational phrases (IP) in Mexico City’s Spanish variety. The speech data was taken from a spontaneous speech corpus made from speakers from two social networks: neighborhood and labor. Final intonation contours of ip show a predominantly rising movement. These contours are generally produced with greater length in the last syllable of the ip, which represents the most significant difference between both networks in the case of oxitone endings. On the other hand, tonemes are predominantly descendant, although the circumflex accent has an important number of cases within the data set. Tonemes produced by the neighborhood network are produced with larger length than those from the labor network.

scholarly journals Holographic RG flows and Janus solutions from matter-coupled $$N=4$$ gauged supergravity

2021 ◽  
Vol 81 (6) ◽  
Author(s):  
Parinya Karndumri
Keyword(s):  
Gauge Group ◽  
The Other ◽  
Three Dimensions ◽  
New Class ◽  
Other Hand ◽  
Genuine Solution ◽  
Coupled Theory

AbstractWe study an $$SO(2)\times SO(2)\times SO(2)\times SO(2)$$ S O ( 2 ) × S O ( 2 ) × S O ( 2 ) × S O ( 2 ) truncation of four-dimensional $$N=4$$ N = 4 gauged supergravity coupled to six vector multiplets with $$SO(4)\times SO(4)$$ S O ( 4 ) × S O ( 4 ) gauge group and find a new class of holographic RG flows and supersymmetric Janus solutions. In this truncation, there is a unique $$N=4$$ N = 4 supersymmetric $$AdS_4$$ A d S 4 vacuum dual to an $$N=4$$ N = 4 SCFT in three dimensions. In the presence of the axion, the RG flows generally preserve $$N=2$$ N = 2 supersymmetry while the supersymmetry is enhanced to $$N=4$$ N = 4 for vanishing axion. We find solutions interpolating between the $$AdS_4$$ A d S 4 vacuum and singular geometries with different residual symmetries. We also show that all the singularities are physically acceptable within the framework of four-dimensional gauged supergravity. Accordingly, the solutions are holographically dual to RG flows from the $$N=4$$ N = 4 SCFT to a number of non-conformal phases in the IR. We also find $$N=4$$ N = 4 and $$N=2$$ N = 2 Janus solutions with $$SO(4)\times SO(4)$$ S O ( 4 ) × S O ( 4 ) and $$SO(2)\times SO(2)\times SO(3)\times SO(2)$$ S O ( 2 ) × S O ( 2 ) × S O ( 3 ) × S O ( 2 ) symmetries, respectively. The former is obtained from a truncation of all scalars from vector multiplets and can be regarded as a solution of pure $$N=4$$ N = 4 gauged supergravity. On the other hand, the latter is a genuine solution of the full matter-coupled theory. These solutions describe conformal interfaces in the $$N=4$$ N = 4 SCFT with $$N=(4,0)$$ N = ( 4 , 0 ) and $$N=(2,0)$$ N = ( 2 , 0 ) supersymmetries.

The Subversion of Plato's Quasi-Phenomenology and Mytho-Poetics in the Symposium

Janus Head ◽  
2009 ◽  
Vol 11 (1) ◽  
pp. 59-76
Author(s):  
Bert Olivier ◽  
Keyword(s):  
Jacques Lacan ◽  
Human Condition ◽  
The Other ◽  
Philosophical Tradition ◽  
The Unconscious ◽  
Other Hand ◽  
Significant Difference ◽  
The One

Is there a significant difference between Plato's texts and what is known as 'Platonism', that is, the philosophical tradition that claims Plato as its progenitor? Focusing on the Symposium, an attempt is made here to show that, far from merely fitting neatly into the categories of Platonism—with its neat distinction between the super-sensible and the sensible—Plato's own text is a complex, tension-filled terrain of countervailing forces. In the Symposium this tension obtains between the perceptive insights, on the one hand, into the nature of love and beauty, as well as the bond between them, and the metaphysical leap, on the other hand, from the experiential world to a supposedly accessible, but by definition super-sensible, experience-transcending realm. It is argued that, instead of being content with the philosophical illumination of the ambivalent human condition—something consummately achieved by mytho-poetic and quasi-phenomenohgical means—Plato turns to a putatively attainable, transcendent source of metaphysical reassurance which, moreover, displays all the trappings of an ideological construct. This is demonstrated by mapping Plato's lover's vision of 'absolute beauty' on to what Jacques Lacan has characterized as the unconscious structural quasi-condition of all religious and ideological illusion.

Distribution of Calcium and Phosphate in Cells of the Enamel Organ in the Rat Lower Incisor

1987 ◽  
Vol 1 (2) ◽  
pp. 236-244 ◽  
Author(s):  
T. Kawamoto ◽  
M. Shimizu
Keyword(s):  
The Other ◽  
Whole Body ◽  
Enamel Organ ◽  
Maturation Stage ◽  
Lower Incisor ◽  
X Ray ◽  
Other Hand ◽  
Freeze Dried ◽  
Significant Difference ◽  
Cell Layers

The distribution of calcium and phosphate in the cells of the enamel organ of the rat lower incisors was investigated by autoradiography and energy-dispersive x-ray spectrometry (EDS). Radioactive calcium or phosphate was injected i.p. into seven-day-old rats of the Wistar strain. The animals were frozen 0.5, 1, and 10 min after injection, and embedded in 5% carboxymethyl cellulose. Sagittal sections of 10 μm thickness were made in which the lower incisor was included as a part of the whole-body section. For autoradiography, the sections were freeze-dried and placed in contact with dry thin films prepared from autoradiographic emulsion. For EDS, sections were mounted on carbon stubs, freeze-dried, coated with carbon, and examined by EDS in a SEM. 45Ca and 32P autoradiograms showed that the radioactivity was located over the papillary layer cells adjacent to the secretory stage ameloblasts and was much higher here than in the ameloblastic layer. On the other hand, there was no significant difference between the amount of radioactivity of these two cell layers in the maturation stage, although higher radioactivity was detectable in the maturation stage enamel than in the secretory stage enamel. Pronounced Ka x-ray peaks were obtained for P, S, Cl, and K originating from the cells of the papillary and ameloblastic layers in the secretory stage, but only very low peaks were obtained for Ca. On the other hand, in addition to these elements, remarkably high Ca and Fe peaks could be detected in the ameloblastic layer of the maturation stage.

Sex Differences in Privacy Preferences

1987 ◽  
Vol 64 (3_suppl) ◽  
pp. 1239-1242 ◽  
Author(s):  
Darhl M. Pedersen
Keyword(s):  
College Students ◽  
Sex Differences ◽  
The Other ◽  
Three Dimensions ◽  
Female College Students ◽  
Female College ◽  
Privacy Preferences ◽  
Other Hand ◽  
The Mean

A Privacy Questionnaire was administered to 118 male and 142 female college students to determine differences in the patterns of privacy preferences between the sexes. The questionnaire contained factor scales for measuring six independent types of privacy. t-tests showed that the means for women were significantly higher than those for men in their preferences for Intimacy with Family and Intimacy with Friends. On the other hand, for Isolation the mean for men was significantly higher than that for women. There were no significant differences between the means for the two sexes on the remaining three dimensions, Reserve, Solitude, and Anonymity.

Angiopoietin-1 and Osteopontin Expression by CD138+ Myeloma Cells Rather Than VEGF and CD45 Correlates with Bone Marrow Angiogenesis in Multiple Myeloma Patients at the Diagnosis.

Blood ◽  
2005 ◽  
Vol 106 (11) ◽  
pp. 2501-2501
Author(s):  
Nicola Giuliani ◽  
Simona Colla ◽  
Francesca Morandi ◽  
Sabrina Bonomini ◽  
Mirca Lazzaretti ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Bone Marrow ◽  
Linear Trend ◽  
The Other ◽  
Vegf Mrna ◽  
Myeloma Cells ◽  
Other Hand ◽  
Significant Difference ◽  
Angiopoietin 1

Abstract Bone marrow (BM) angiogenesis is increased in Multiple Myeloma (MM) patients and correlates with disease progression and patient survival. Myeloma cells secrete the main endothelial growth factor VEGF. In mouse models VEGF secretion as well as the angiogenic properties of MM cells correlate with the lack of CD45 expression by MM cells. However, recent data indicate that VEGF plasma cell expression is similar between MGUS and MM patients suggesting that other molecules could be involved. In line with this hypothesis we have recently demonstrated that myeloma cells may also produce factors with angiogenic properties as angiopoietin-1 (ANG-1) and osteopontin (OPN) that are involved in myeloma induced angiogenesis in vitro. In order to identify which factors correlate with BM angiogenesis in MM patients, we have investigated in a cohort of 121 newly diagnosed MM patients (stage I–III) the expression of the angiogenic molecules VEGF, ANG-1 and OPN and their correlation with bone marrow (BM) angiogenesis and CD45 expression by MM cells. We found that 90% of CD138+ MM cells tested were positive for VEGF mRNA. On the other hand we found that 50% and 40 % of MM patients were positive for ANG-1 and OPN mRNA respectively. Using the previously published cut off for CD45 expression we found that 61 out of 121 MM patients were positive for CD45 and 60 out of 121 were negative for CD45 expression. Any correlation was not observed between VEGF expression and BM angiogenesis in MM patients (p=0.5), whereas the number of microvessels X field was higher in Ang-1 positive patients in comparison with Ang-1 negative ones (mean±SE: 6.23±0.2 vs. 2.94±0.1, median: 6.21 vs. 2.79; p=0.001,) and the microvascular density (MVD) was significantly increased (32.98±1.7 vs. 14.55±1.3, median: 34.69 vs. 13.04; p&lt;0.01; capillaries: 26.73±1.3 vs. 10.42±0.8, median: 24.06 vs. 9.04; p&lt;0.01, small venules: 9.56 ±0.5 vs. 4.14±0.5, median: 10.60 vs. 3.65; p&lt;0.01). Furthermore a significantly positive correlation between Ang-1 expression and MVD was found (Pearson Chi-square: p=0.036, Cochran’s Linear Trend: p=0.01). A significantly higher MVD was also observed in the group of patients positive for OPN, (mean±SE: 29.1±0.7 vs. 17.55±0.37; p&lt;0.01) and similarly, the number of microvessels per field was higher in OPN positive patients in comparison with OPN negative ones (mean±SE: 6.7±0.15 vs. 4.28±0.04; p=0.05). On the other hand, any significant difference was not observed between CD45 positive and CD45 negative patients for the expression of VEGF (p=0.4), ANG-1 (p=0.3) and OPN (p=0.09). Consistently we did not find any significant difference in both MVD and number of vessels X field between CD45 positive patients as compared with CD45 negative ones (p=0.5 and p=0.4, respectively). Finally, a multivariate analysis confirmed that VEGF and CD45 did not correlate with the BM angiogenesis showing that ANG-1 expression by MM cells was more tightly correlated with MVD and the number of vessels X field as compared to OPN. Our data indicate that ANG-1 and in part OPN rather than VEGF and CD45 expression by MM cells are the critical determinants correlated with the increase of BM angiogenesis that occurs in MM patients at the diagnosis.

Difference of Treatment Outcomes in AL Amyloidosis and Multiple Myeloma with / without Translocation (11;14)

Blood ◽  
2015 ◽  
Vol 126 (23) ◽  
pp. 4224-4224 ◽  
Author(s):  
Kenshi Suzuki ◽  
Miho Kasuga ◽  
Kanji Miyazaki ◽  
Sohsuke Meshitsuka ◽  
Yu ABE ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Overall Survival ◽  
Chromosome Aberration ◽  
The Other ◽  
Cardiac Response ◽  
Al Amyloidosis ◽  
Positive Group ◽  
Other Hand ◽  
Significant Difference ◽  
Organ Response

Abstract Introduction AL amyloidosis (AL) is characterized by the deposition of immunoglobulin light chains as amyloid fibrils accumulated in different organs. Translocation (11;14) (t(11;14)) is seen in about half of AL patients, but the clinical significance is still unknown. So our study has focused on the chromosome aberration of t(11;14). We report the relationship between the chromosome aberration and the organ response, the organ involvement which greatly influence prognosis of AL patients. Furthermore, we examined the prognosis and treatment response to compare t(11;14) influences of AL with t(11;14) influences of multiple myeloma (MM). Patients and Methods We analyzed in AL and symptomatic MM patients have t(11;14) using fluorescence in situ hybridization from January 2010 to December 2014 in Japanese Red Cross Medical Center. We examined the overall survival and the therapy response rate. In addition, we compared t(11;14)-positive and negative in AL and MM respectively. Besides, we investigated the involved organ parts and the organ response with melphalan and dexamethasone (MD) therapy in AL. Outcome was assessed based on remission after three months and one year. Remissions were determined according to consensus criteria in 2011 for AL and IMWG uniform criteria for MM. Survival distribution of OS was estimated using the Kaplan-Meier method and compared using the log-rank test. Data between t(11;14)-positive and negative were compared with the Mann-Whitney U test or X2 test. The statistical analysis was performed using IBM SPSS statistics ver.23. Results Among 27 patients with AL, 9 cases were t(11;14)-positive patients (age median, 64yr; range, 37-80), and 13 out of 46 were positive in MM (age median, 64yr; range, 34-86). (excluded complication of both AL and MM cases) In AL cases, the t(11;14)-positive group tended to shorter overall survival (OS) than negative cases. On the other hand, in the patients with MM, positive group tended to superior OS to negative (AL: P=0.442(Fig.1A), MM: P=0.327(Fig.1B)). Compared with t(11;14)-negative AL group, t(11;14) positive group was tended to have much organ involved numbers of amyloid protein (67% v 34%; P=0.109) and much cardiac involvement patients (67% v 39%; P=0.171). On the other hand, there were little cardiac and renal response in both t(11;14)-positive and negative with MD therapy after 3 months (heartF17% v 0% P=0.462/renalF0% v 0%). In MM patients, ORR after 3 months were 67% and 79% in t(11;14)-positive and negative cases respectively (P=0.386). That after 1 year were 78% and 74% respectively (P=0.889). Conclusion t(11;14) is important prognostic factor and showed conflict prognosis between AL and MM. From this investigation, the importance of connecting the chromosome abnormality every disease was shown. In addition, our investigation recognized tendencies that the amyloid involvement rate to the heart was high, and the cardiac response with MD therapy were low in AL t(11;14)-positive group. As these results, we thought that t(11;14)-positive AL patients' OS were shortened. The significant difference did not appear in this examination while these tendencies were clearly accepted in little number of patient cases. Further investigation using rather number of patient samples is needed. In conclusion, the cardiac amyloid involvement is high in the AL t(11;14)-positive group, and the cardiac response by MD therapy is low. We should have doubt eyes of the amyloid involvement to the heart in AL t(11;14)-positive patients, and have the posture that can support cardiac amyloidosis immediately. In addition, breakthrough new treatments are expected urgently for AL patients. Figure 1. Figure 1. Disclosures No relevant conflicts of interest to declare.

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