Pneumococcal infection in Russia: state of the issue

2021 ◽  
Vol 76 (1) ◽  
pp. 28-42
Author(s):  
Nikolay I. Briko ◽  
Vladimir A. Korshunov ◽  
Kirill S. Lomonosov
Keyword(s):  
Adult Population ◽  
Herd Immunity ◽  
Pneumococcal Infection ◽  
Community Acquired Pneumonia ◽  
Morbidity And Mortality ◽  
School Age Children ◽  
Economic Significance ◽  
Chronic Lung Diseases ◽  
One Year ◽  
High Level

Background: Pneumococcal disease is common cause of morbidity and mortality in adults and children worldwide. The severity of pneumococcal diseases determines their high socio-economic significance. Aims: Estimate the burden of pneumococcal infection and vaccination coverage in Russia. Methods: The data was obtained from federal surveillance system. The information obtained was analyzed using descriptive statistics methods. Results: The annual incidence of community-acquired pneumonia in Russia was 491.7/100000 in 2011-2019. It ranges from 359.8/100000 among adults of working age to 1505.4/100000 among children 1-2 years old. The upward trend of incidence is observed throughout the period, most expressive among school-age children (7-17 years old). Total 29.2% of all pneumonia have an identified etiology. 94% of pneumonia with known etiology are bacterial, 8.4% among it are pneumococcal. Pneumonia accounts for 57% of all deaths from respiratory diseases among children under five (3.7/100000) and 34% among elderly. The death rate from pneumonia in 2009-2018 tends to decrease. In 2018, 25.5 thousand deaths from pneumonia were registered (17.5/100000). The highest rate is observed among children under one year (14.0 /100000) and elderly (41.2 /100000). There is a downward trend in incidence of otitis media. The incidence in children under 14 was 2612.6/100 000 in 2018. The incidence of bacterial meningitis is 1.4/100 000. Every year 2-3 thousand cases are registered, 43-52% of which are among children (3.04/100000., maximally in children under one year old, 13.2/100000). The level of vaccination against pneumococcal infection is increasing annually, but the proportion of children who have received a completed course of vaccination remains insufficient (64.6% in 2019). Coverage among the adult population was 2.3% (3.8% among those over 60). The main contingents of vaccinated adults are conscripts (coverage 67.4%) and people with chronic lung diseases (coverage 15.1%). Conclusions: The socio-economic and epidemiological burden of diseases associated with pneumococcal infection in Russia remains high. Accurate assessment of morbidity and mortality rates caused by St. pneumoniae diseases isnt possible due to the insufficient level of their ethological identification. Further efforts are required to achieve high level of herd immunity against pneumococcal infection through vaccine prevention during COVID-19 pandemic.

scholarly journals Factors Influencing SARS-CoV-2 Vaccine Acceptance and Hesitancy in a Population-Based Sample in Italy

Vaccines ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 633
Author(s):  
Marco Del Riccio ◽  
Sara Boccalini ◽  
Lisa Rigon ◽  
Massimiliano Alberto Biamonte ◽  
Giuseppe Albora ◽  
...  
Keyword(s):  
Online Survey ◽  
Adult Population ◽  
Herd Immunity ◽  
Population Based ◽  
Vaccine Hesitancy ◽  
Convenience Sample ◽  
Major Barrier ◽  
Trust In Institutions ◽  
General Adult Population ◽  
High Level

Vaccination against SARS-CoV-2 represents an effective and safe tool to protect the population against the disease; however, COVID-19 vaccine hesitancy could be a major barrier to achieving herd immunity. Despite the severity of the current pandemic, the population’s intention to get vaccinated against COVID-19 is still not clear. The aim of this study was to evaluate the intention to get vaccinated against COVID-19 among a convenience sample of the general population resident in Italy and the factors associated with hesitancy and acceptance of the vaccine in the context of the current pandemic before the rolling out of COVID-19 vaccines. An anonymous online survey was diffused among a general adult population living in Italy. Participants aged 18 or older and living in Italy were considered eligible. Incomplete questionnaires were excluded. Overall, 7605 valid questionnaires were collected. Most of the participants (81.9%) were inclined to get vaccinated; male sex (OR 1.38, 95% CI 1.12–1.71), a high level of trust in institutions (OR 3.93, 95% CI 2.04–7.83), and personal beliefs about high safety of COVID-19 vaccines (OR 56.33, 95% CI 31.57–105.87) were found to be among the significant predictors of COVID-19 acceptance. These data could help design larger studies to address the problem of COVID-19 vaccine hesitancy in the current pandemic.

scholarly journals ANALYSIS OF THE EFFECTIVENESS OF THE IMPLEMENTATION OF THE PILOT PROJECT OF VACCINATION AGAINST PNEUMOCOCCAL INFECTION IN RISK GROUPS IN THE MUNICIPALITIES LEADING ON INDICATORS OF MORTALITY FROM COMMUNITY-ACQUIRED PNEUMONIA

2018 ◽  
pp. 24-26
Author(s):  
I.I. Kozlova ◽  
E.I. Sisin ◽  
N.A. Ostapenko ◽  
O.A. Ezhova ◽  
N.G. Kashapov
Keyword(s):  
Pneumococcal Disease ◽  
Pneumococcal Infection ◽  
Risk Groups ◽  
Pilot Project ◽  
Mortality Rates ◽  
Community Acquired Pneumonia ◽  
Morbidity And Mortality

There were established municipalities with the highest mortality rates from community-acquired pneumonia (CAP). When etiological deciphering of CAP confirmed the role of S. pneumoniae (Klein) Chester in the development and outcome of this disease. Among the risk contingents were vaccinated against pneumococcal disease, which had an impact on morbidity and mortality from CAP. It is proved that the vaccination of contingent risk against pneumococcal disease reduces the morbidity and mortality from CAP.

THE USE OF IMMUNOLOGICAL INDICATORS IN ORDER TO FORM AN IMMUNOCOMPROMISED GROUP FOR VACCINATION AGAINST PNEUMOCOCCAL INFECTION

2021 ◽  
Author(s):  
T.V. Bushueva ◽  
◽  
N.A. Roslay ◽  
A.K. Labzova ◽  
Keyword(s):  
Adult Population ◽  
Pneumococcal Infection ◽  
Professional Groups ◽  
Production Factors ◽  
Working Age ◽  
High Level ◽  
Families With Children ◽  
Secretory Immunoglobulin ◽  
Healthy Carriers ◽  
Increased Susceptibility

Abstract: Pneumococci (Streptococcus pneumoniae) are one of the leading causes of morbidity and mortality among people over 60 years of age and workers in some professional groups. According to the medical literature, the frequency of invasive forms of pneumococcal infection among people of working age is 3.8 per 100,000 population. Increased susceptibility to colonization of the respiratory tract and subsequent morbidity may be due to concomitant pathology, exposure to immunocompromising, including harmful production factors. It should be noted that the source of the pathogen is not only sick people, but also healthy carriers. The level of asymptomatic colonization in the adult population is 5-7%, and in families with children increases to 30%. Vaccination is a way to effectively prevent respiratory diseases caused by this infection. The purpose of our study is to substantiate immunological indications for the formation of immunocompromised groups among workers exposed to the aerogenic factor at work for subsequent vaccination against pneumococcal infection. Results: It has been shown that low bactericidal activity of neutrophils (NBT-test) and a high level of secretory immunoglobulin can be used as a marker of immunodeficiency in workers of a ferrous metallurgy enterprise. When a doctor assesses the immune status of workers, he needs to take into account the presence of diseases that are part of the groups of immunological syndrome complexes (infectious-inflammatory, autoimmune, allergic, immunoproliferative) and the composition of industrial aerosols

scholarly journals Epidemiological and economic efficiency of mass vaccinal prevention against pneumococcal infection in children compared with selective immunization at the example of community-acquired pneumonia

2019 ◽  
Vol 36 (4) ◽  
pp. 63-73 ◽  
Author(s):  
Vadislav V. Semerikov ◽  
Elena S. Zubova ◽  
Lyudmila V. Sofronova
Keyword(s):  
High Risk ◽  
Economic Efficiency ◽  
Pneumococcal Infection ◽  
Economic Benefits ◽  
Community Acquired Pneumonia ◽  
High Risk Group ◽  
Mass Vaccination ◽  
Morbidity And Mortality ◽  
First Year ◽  
First Year Of Life

Aim. To study the epidemiological pattern of community-acquired pneumonias in children and the influence of mass vaccinal prevention on morbidity and mortality. Materials and methods. Vaccination of children against pneumococcal infection on the territory of a large industrial center of Western Urals was analyzed, influence of mass vaccination against pneumococcal infection on pneumonia morbidity and mortality in children was determined. Results. Mass vaccinal prevention of children of the first year of life against pneumococcal infection (vaccination volume 102 353.6 per 100 thousand children under 6) significantly influenced morbidity level regarding community-acquired pneumonias in the group of vaccinated children under 2 (1619.9 0.78 versus 15233.7 2.5 per 100 thousand in the group of unvaccinated, odds ratio and its confidence interval was 9.40 [95 % CI 8.4610.44]), on community-acquired streptococcal morbidity of children under 6 (r = 0.97; regression coefficient = 36.30, р 0.001; R2 = 91.0 %, significance F = 0.01 and possibility 95.0 %) and 5-fold decreased the mortality level (from 35.2 before vaccination started to 6.8 per 100 thousand) till its full absence in the third year of realization of this strategy. No analogous influence on the main manifestations of epidemiological process of community-acquired pneumonia was noted in case of selective immunization against pneumococcal infection among 25 year olds, belonging to high risk groups (vaccination volume 10 417.08 per 100 thousand children under 6). Conclusions. The strategy of mass vaccination of children of the first year of life was characterized by the greatest epidemiological and economic benefits. Economic efficiency taking into account vaccination costs in terms of 1000 of vaccinated children was 17.1 times higher and was equal to 8.3656 mln rub per 1000 inhabitants versus 0.4890 mln rub in case of selective immunization of high risk group children.

scholarly journals CLINICAL AND EPIDEMIOLOGICAL ASSESSMENT OF THE EFFECTIVENESS OF VACCINATION OF CHILDREN AGAINST PNEUMOCOCCAL INFECTION IN THE AMUR REGION

2016 ◽  
pp. 57-63 ◽  
Author(s):  
A. G. Chuchalin ◽  
G. G. Onischenko ◽  
V. P. Kolosov ◽  
O. P. Kurganova ◽  
N. L. Tezikov ◽  
...  
Keyword(s):  
Hospital Admissions ◽  
Pneumococcal Infection ◽  
Acute Otitis Media ◽  
Total Duration ◽  
Monitoring Program ◽  
Pneumococcal Vaccination ◽  
Community Acquired Pneumonia ◽  
Amur Region ◽  
Pneumococcal Infections ◽  
High Level

Aim. To study the effectiveness of anti-pneumococcal vaccination of children in the organization of anti-epidemic measures in the areas of the flood in the Amur region. Material and methods. The monitoring program included 4988 children aged 2 to 5 years who have risk factors for pneumococcal infection. Pneumococcal conjugate vaccine Prevenar-13 was used for immunization. Data on the incidence of child with acute respiratory infection, acute otitis media, pneumonia, meningitis during the post-vaccination period were taken into account. To evaluate the effectiveness of vaccination we used indicators and specific criteria (coefficient prophylactic vaccination and infection index). Results. The level of total morbidity of children in post-immunization period decreased by 13.6%; the number of cases of pneumonia in the population of observed children decreased by 2.3 times; the total duration of the illness in children decreased by 14.6%, the number of courses of antibiotic therapy was reduced by 21.3%, the number of hospital admissions of children- 38.4%, the number of days of temporary disability of parents - 11.1%. Direct dependence of the degree of effectiveness of vaccination against pneumococcal disease by the age of children is determined. Conclusion. The findings suggest that implementation of the program of clinical and epidemiological monitoring and prevention of community-acquired pneumonia with use of a vaccine against pneumococcal infections in the territory of the Amur Region has a high level of medical and socio-economic efficiency.

scholarly journals Knowledge and attitude of people above 18 years regarding COVID-19 vaccination in a rural area of Kerala

2021 ◽  
Author(s):  
Suchithra Erath Thadathil ◽  
Rithu N. ◽  
Sindhu P. S.
Keyword(s):  
Adult Population ◽  
Herd Immunity ◽  
Sampling Technique ◽  
Cross Sectional Study ◽  
Control Measures ◽  
Cluster Sampling ◽  
Prevention Measures ◽  
Cross Sectional ◽  
Knowledge And Attitude ◽  
High Level

Background: The COVID vaccination programme in conjunction with other control measures, are needed to control the COVID-19 pandemic. The mass vaccination with COVID vaccines, will help to increase the herd immunity. This study is an attempt to assess the knowledge and attitude of the adult population of a panchayat area of Thrissur district of Kerala towards COVID-19 vaccination and socio-demographic determinants associated with it.Methods: We have done a cross-sectional study among 350 study participants selected by cluster sampling technique from a panchayat area of Thrissur district of Kerala and the data was collected, using a pretested semi structured questionnaire. The knowledge and attitude were assessed by proportion and association of socio-demographic determinants was found out using ‘t’ test and ‘ANOVA’ test.Results: The result obtained, showed 94.3% of persons responded that there is a vaccine for preventing COVID and 85.2% were aware that Covishield and Covaxin were the vaccine freely available. The 78.3% respondents knew that there should be 84 days between the doses of Covishield and 77.1% knew that 28 days for Covaxin. The 100% respondents had attitude to take the vaccine and 99.1% were ready to continue COVID prevention measures even after vaccination. As per this study, younger age (p=0.04) and religion (0.000) had an association with knowledge.Conclusions: The high level of knowledge and a100% attitude towards COVID vaccination may be due to high political will and accountability of the governments towards it. The places with low acceptance rate can be able to model on it.

scholarly journals Analysis of the incidence of community-acquired pneumonia and acute otitis media in children during the first four years of life in different age groups vaccinated with pneumococcal 13-valent vaccine Prevenar

2019 ◽  
Vol 10 (3) ◽  
pp. 49-56
Author(s):  
S. A. Pyrkova ◽  
L. P. Voronina ◽  
M. E. Kuzin ◽  
V. V. Cherepova ◽  
E. A. Polunina
Keyword(s):  
Otitis Media ◽  
Age Groups ◽  
Pneumococcal Infection ◽  
Acute Otitis Media ◽  
Community Acquired Pneumonia ◽  
Good Tolerability ◽  
Post Vaccination ◽  
High Level ◽  
Disease Analysis ◽  
Vaccination Period

Objective: to analyze the incidence of community-acquired pneumonia and acute otitis media in children during the first four years of life in different age groups vaccinated with pneumococcal 13-valent vaccine Prevenar.Materials and methods: medical records of 590 children aged 1 to 5 years were analyzed. All subjects were divided into 2 groups. The first group consisted of vaccinated children (n = 490), born in 2014, and vaccinated against pneumococcal 13-valent vaccine Prevenar. The second group consisted of unvaccinated children (n = 100) born in 2013 and not vaccinated. Each group was divided into subgroups depending on the age period (1—2 years, 2—3 years, 3—4 years, 4—5 years).Results: it is established that the conduct of specific prophylaxis of pneumococcal infection vaccine Prevenar-13 in children during the first 4 years of life effectively reduces the incidence of community-acquired pneumonia (in 7,6 times) and acute otitis media (in 8,5 times). The effectiveness of the vaccine was observed in all age groups. In cases of development of an inoculated child acute otitis reduces the risk of severe forms and complications of the disease. Analysis of the course of the post-vaccination period indicates a high level of safety and good tolerability of the vaccine.Conclusion: Implementation of specific prophylaxis of pneumococcal 13-valent vaccine Prevenar in children during the first four years of life according to the calendar of vaccination effectively reduces the incidence of community-acquired pneumonia (87 %) and acute otitis media (42,8 %) in all age subgroups. In cases of development of an inoculated child acute otitis reduces the risk of severe forms and complications of the disease. Analysis of the course of the post-vaccination period indicates a high level of safety and good tolerability of the vaccine.

scholarly journals The Effect of Selective and Mass Immunization Against Pneumococcal Infection on the Morbidity and Mortality due to Community-Acquired Pneumonia in Children Under 5 Years of Age

2019 ◽  
Vol 16 (4) ◽  
pp. 216-228
Author(s):  
Vadislav V. Semerikov ◽  
Elena S. Zubova ◽  
Lyudmila V. Sofronova
Keyword(s):  
Pneumococcal Infection ◽  
Chronically Ill ◽  
Community Acquired Pneumonia ◽  
Mass Vaccination ◽  
Morbidity And Mortality ◽  
Morbidity Rate ◽  
Mass Immunization ◽  
Cost Efficacy ◽  
Selective Vaccination ◽  
Children Under 5

Background. It is required to perform estimation of epidemiological and cost efficacy (regarding morbidity rate) of mass routine vaccination against pneumococcal infection in Russian children and carried out earlier selective vaccination of children from high-risk groups on the basis of four-year experience. It is also important to estimate the rate of hospital admissions in this patient group, long-term and annual cycles, morbidity age and etiology structure, and mortality due to community-acquired pneumonia as one of the most common form of pneumococcal disease. The aim is to study the effect of selective and mass immunization against pneumococcal infection on the morbidity and mortality due to community-acquired pneumonia in children under 5 years of age. Methods. The analysis of communityacquired pneumonia morbidity (in 2003–2018) and mortality due to pneumonias (in 2003–2018) in children under the 14 years old in Perm was carried out. Serotypes of circulating pneumococcus, etiology of community-acquired pneumonias and immunization cost efficacy (direct expense on health care) were further studied. The analysis of study indexes was carried out following selective (vaccination of at-risk children in 2011–2014) and mass (vaccination of infants in 2015–2018) immunization strategies. Results. The morbidity rate of community-acquired pneumonias decreased by 4.0 times (from 267.0 to 66.7 for 1000) after performing selective vaccination (2011–2014) in at-risk children (frequently and chronically ill children). The morbidity rate of community-acquired pneumonias in non vaccinated children of the same group increased by 2.0 times (from 40.0 to 80.0 for 1000 non-vaccinated). The prophylactic efficacy index was 46.0. Whereby the antibacterial index among vaccinated frequently and chronically ill children was 0.11 on one child. This index has decreased by 2.6 times (from 0.11 to 0.04 on one child) in a year within the framework of prospective controlled randomized clinical study. The antibacterial index among non-vaccinated children of this group remained slightly the same: 0.09 and 0.12 respectively. During the selective vaccination the mortality rate among infants decreased by 2 times: long-term average index was 17.9 (2011–2014) against 35.2 (2003-2010) on 100 thousand children. Mass vaccination of infants against pneumococcal infection has reduced the incidence of community-acquired pneumonias among children under 2 years of age and has led to absence of multiple sites of pneumococcal infection in children’s organizations. It also has reduced the number of hospitalized children and achieved zero mortality due to pneumonias in infants by the third year of this immunization strategy implementation. The obtained results were achieved mainly due to circulation of 7 pneumococcal serotypes (6A, 6B, 9V, 14, 19A, 19F, 23F) in children under 5 years of age. The threshold level of vaccination against pneumococcal infection advancing morbidity and mortality due to pneumonias in children was specified. The strategy of mass vaccination of infants was cost-effective. Conclusion. The new data on epidemiological and cost efficacy of various immunization strategies against pneumococcal infection in children was obtained.

COMMUNITY-ACQUIRED PNEUMONIA AS AN URGENT PROBLEM OF MODERN SOCIETY

2021 ◽  
pp. 57-70
Author(s):  
V.A. Serov ◽  
V.V. Gnoevykh ◽  
D.V. Serova ◽  
E.R. Sakaeva
Keyword(s):  
Respiratory Diseases ◽  
Kidney Injury ◽  
Modern Society ◽  
Community Acquired Pneumonia ◽  
Preventive Health ◽  
Health Messages ◽  
Diagnostic Methods ◽  
Economic Significance ◽  
Treatment And Prevention ◽  
High Level

Community-acquired pneumonia (CAP) is one of the leading causes of morbidity and mortality worldwide. However, there are still many unresolved issues in prevention, diagnosis and treatment of the disease despite its enormous social and economic significance. Mortality associated with CAP in elderly patients is increasing, as the proportion of people over 65 is growing every year. The purpose of this review is to consider the most significant issues in CAP diagnostics and treatment, that will improve the quality of medical care and prognosis of CAP patients. Data from Pubmed, eLIBRARY, and other sources were used to collect the information. The lack of an adequate etiological diagnosis of bacterial CAP has led to unjustified antibacterial therapy, which contributes to the spread of antibiotic-resistant strains of microorganisms and increase in side effects of antibiotics. During COVID-19 pandemic, it has become even more difficult etiologically to diagnose infectious respiratory diseases. The lack of knowledge about the peculiarities of managing patients with comorbid pathology has become more evident. Everyone has understood that the severity of bronchopulmonary diseases was underestimated by the population. Acute kidney injury (AKI) is one of the most formidable CAP complications. The authors describe pathogenetic mechanisms of renal dysfunction, diagnostic methods, AKI treatment and prevention in patients with CAP. Underestimation of the forecast severity, both medium-term and long-term, in patiemts with CAP leads to an insufficiently high level of immunization against influenza and pneumococcus. The authors declare that it is desirable to pay much attention to preventive health messages not only relating to cardiovascular or oncological diseases, but also infectious respiratory diseases. Keywords: community-acquired pneumonia, microbiological diagnostics, comorbidity, preventive health messages. Внебольничная пневмония (ВП) является одной из главных причин заболеваемости и смертности населения во всем мире. Однако несмотря на огромную социально-экономическую значимость этой патологии остается большое количество нерешенных вопросов по профилактике, диагностике и лечению данного заболевания. Особую тревогу вызывает увеличение смертности от ВП у пациентов пожилого возраста, так как во всех развитых странах удельный вес лиц старше 65 лет с каждым годом растет. Целью настоящего обзора является рассмотрение наиболее значимых проблем диагностики и лечения ВП, решение которых позволит повысить качество оказания медицинской помощи и улучшить прогноз пациентов с ВП. В качестве источников информации использовались данные электронных библиотек Pubmed, eLIBRARY и др. Отсутствие адекватной этиологической диагностики бактериальной ВП привело к серьезной опасности необоснованной антибактериальной терапии, которая способствует распространению антибиотикорезистентных штаммов микроорганизмов и росту частоты побочного действия антибиотиков. В период коронавирусной пандемии особенно ярко проявились трудности этиологической диагностики инфекционных заболеваний дыхательных путей, недостаточность знаний об особенностях ведения больных с коморбидной патологией, недооценка населением серьезности бронхолегочных заболеваний. Одним из наиболее грозных осложнений ВП является острое повреждение почек (ОПП). Авторы описывают патогенетические механизмы нарушения функции почек, методы диагностики, тактику лечения и профилактики ОПП при ВП. Недооценка серьезности прогноза, в т.ч. средне- и долгосрочного, при ВП ведет к недостаточно высокому уровню использования вакцин против гриппа и пневмококка. Обращает на себя внимание необходимость усиления санитарно-просветительской работы с населением в отношении не только сердечно-сосудистых или онкологических заболеваний, но и инфекционных заболеваний дыхательных путей. Ключевые слова: внебольничная пневмония, микробиологическая диагностика, коморбидность, санитарное просвещение.

scholarly journals The Results of a Three-Year Pneumococcal Vaccination of Children in Russia

2018 ◽  
Vol 15 (4) ◽  
pp. 287-299 ◽  
Author(s):  
Nikolay I. Briko ◽  
Vladimir A. Korshunov ◽  
Leyla S. Namazova-Baranova ◽  
Juriy V. Lobzin ◽  
Alexander A. Baranov ◽  
...  
Keyword(s):  
Otitis Media ◽  
Russian Federation ◽  
Pneumococcal Infection ◽  
Acute Otitis Media ◽  
Pneumococcal Vaccination ◽  
Vaccination Schedule ◽  
Community Acquired Pneumonia ◽  
Morbidity And Mortality ◽  
Prophylactic Vaccination ◽  
The Russian Federation

Background.After inclusion of pneumococcal vaccination in the National Vaccination Schedule, it is very important to evaluate the efficacy of routine immunisation of the child population for more than 3 years. The obtained results provide opportunity to analyse the problems in achieving the goal, determine their causes, and suggest the ways of overcoming. Our aim was to study the results of a three-year period of pneumococcal vaccination of children.Methods.The quality of immunoprophylaxis of pneumococcal infection in the territory of the Russian Federation were assessed by analysing the coverage of vaccination and timeliness of its conduct after the inclusion of pneumococcal vaccine in the National Vaccination Schedule. The actual epidemiological efficacy of pneumococcal vaccination was assessed based on morbidity and mortality due to community-acquired pneumonia, incidence of acute otitis media among children. By questioning parents (n = 352) who applied to the Federal State Autonomous Institution of the Russian Federation Ministry of Health ‘National Medical Research Centre for Children’s Health, the timeliness of pneumococcal vaccination for infants was established.Results.In most regions, a high level of pneumococcal vaccination coverage was reached (87% of children). Despite the fact that the majority of children (73%) were vaccinated untimely. In particular, the results of a questionnaire survey conducted in the Moscow vaccination centre indicate insufficient awareness of parents for the need to vaccinate infants against pneumococcal infection by primary care professionals and, as a consequence, a low level of timely initiated vaccine introduction (40.1%). The introduction of routine prophylactic pneumococcal vaccination in Russia resulted in a 35% reduction in the death rate of children from community-acquired pneumonia, led to a decrease in the incidence of acute otitis media.Conclusion.The introduction of routine prophylactic vaccination of children against Streptococcus pneumoniae helps to reduce morbidity and mortality from pneumococcal infections. The surveillance system for community-acquired pneumonia requires further improvement. It is advisable to conduct an additional analysis on the reasons for refusals and medical exemptions to vaccination. It is important to increase the professional level of paediatricians in prophylactic vaccination.

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