Factors Influencing SARS-CoV-2 Vaccine Acceptance and Hesitancy in a Population-Based Sample in Italy

Vaccination against SARS-CoV-2 represents an effective and safe tool to protect the population against the disease; however, COVID-19 vaccine hesitancy could be a major barrier to achieving herd immunity. Despite the severity of the current pandemic, the population’s intention to get vaccinated against COVID-19 is still not clear. The aim of this study was to evaluate the intention to get vaccinated against COVID-19 among a convenience sample of the general population resident in Italy and the factors associated with hesitancy and acceptance of the vaccine in the context of the current pandemic before the rolling out of COVID-19 vaccines. An anonymous online survey was diffused among a general adult population living in Italy. Participants aged 18 or older and living in Italy were considered eligible. Incomplete questionnaires were excluded. Overall, 7605 valid questionnaires were collected. Most of the participants (81.9%) were inclined to get vaccinated; male sex (OR 1.38, 95% CI 1.12–1.71), a high level of trust in institutions (OR 3.93, 95% CI 2.04–7.83), and personal beliefs about high safety of COVID-19 vaccines (OR 56.33, 95% CI 31.57–105.87) were found to be among the significant predictors of COVID-19 acceptance. These data could help design larger studies to address the problem of COVID-19 vaccine hesitancy in the current pandemic.

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COVID-19 Vaccine Hesitancy and Resistance in India Explored through a Population-Based Longitudinal Survey

Vaccines ◽

10.3390/vaccines9101064 ◽

2021 ◽

Vol 9 (10) ◽

pp. 1064

Author(s):

Srikanth Umakanthan ◽

Sonal Patil ◽

Naveen Subramaniam ◽

Ria Sharma

Keyword(s):

Hot Spots ◽

Online Survey ◽

Population Based ◽

World Health ◽

Vaccine Hesitancy ◽

Role Of Government ◽

Adverse Health Effects ◽

Health Organization ◽

High Level

Background: The World Health Organization has recommended that individual governments identify vaccine hesitancy areas. It is proposed that the governments, with the aid of local organizations, educate and implement social insights on the vaccination so that high population levels are covered with this safe immune program. Methods: A longitudinal online survey covered 3000 adults from India. We examined the demography, behavioral (socio-economic) attitude, vaccine hesitancy, vaccine resistance for the COVID-19 vaccine. The specific reasons for the COVID-19 vaccine decline were also evaluated. Results: Our survey revealed 59% definite response, 29% low-level response, and 7% high-level response for vaccine hesitancy, while 6% had resistant views on the COVID-19 vaccine. Individuals who had higher income levels, lived in a society, maintained social distancing, had downloaded the COVID-19 update app, showed a positive attitude towards their government, and more confidence in their healthcare system were more inclined towards the vaccination. On the contrary, individuals who had overstated the risks of COVID-19 and had a religious and populistic attitude towards vaccination were more hesitant/resistant to vaccination. The respondents who declined vaccine administration were further evaluated for their specific reason for their response. The most common reasons for declining the COVID-19 vaccine were post-vaccine scare of adverse health effects and accepting the information spread by social media. Conclusions: The results in our study show that by identifying population “hot spots” that have negative or unclear information on the COVID-19 vaccination, these “hot spots” can be addressed by involving friendly organizations that can clear their strong disbeliefs and increase the percentage of vaccine-definite people within the population. The role of government-induced COVID-19 vaccine policy measures can always be beneficial to cause this shift from disbelief to confidence within the population.

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Would Parents Get Their Children Vaccinated Against SARS-CoV-2? Rate and Predictors of Vaccine Hesitancy According to a Survey over 5000 Families from Bologna, Italy

Vaccines ◽

10.3390/vaccines9040366 ◽

2021 ◽

Vol 9 (4) ◽

pp. 366

Author(s):

Marco Montalti ◽

Flavia Rallo ◽

Federica Guaraldi ◽

Lapo Bartoli ◽

Giulia Po ◽

...

Keyword(s):

Online Survey ◽

Vaccination Campaign ◽

Herd Immunity ◽

Vaccine Hesitancy ◽

Web Based ◽

Safe School ◽

Efficacy Trials ◽

Adolescent Vaccination ◽

Web Social ◽

Mandatory Vaccination

In the near future, COVID-19 vaccine efficacy trials in larger cohorts may offer the possibility to implement child and adolescent vaccination. The opening of the vaccination for these strata may play a key role in order to limit virus circulation, infection spreading towards the most vulnerable subjects, and plan safe school reopening. Vaccine hesitancy (VH) could limit the ability to reach the coverage threshold required to ensure herd immunity. The aim of this study was to investigate the prevalence and determinants of VH among parents/guardians toward a potentially available COVID-19 vaccination for children and adolescents. An online survey was performed in parents/guardians of children aged <18 years old, living in Bologna. Overall, 5054 questionnaires were collected. A vast majority (60.4%) of the parents/guardians were inclined to vaccinate, while 29.6% were still considering the opportunity, and 9.9% were hesitant. Highest vaccine hesitancy rates were detected in female parents/guardians of children aged 6–10 years, ≤29 years old, with low educational level, relying on information found in the web/social media, and disliking mandatory vaccination policies. Although preliminary, these data could help in designing target strategies to implement adherence to a vaccination campaign, with special regard to web-based information.

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The Prevalence of Sexual Abuse in Institutions: Results From a Representative Population-Based Sample in Germany

Sexual Abuse ◽

10.1177/1079063218759323 ◽

2018 ◽

Vol 31 (6) ◽

pp. 643-661 ◽

Cited By ~ 5

Author(s):

Andreas Witt ◽

Miriam Rassenhofer ◽

Marc Allroggen ◽

Elmar Brähler ◽

Paul L. Plener ◽

...

Keyword(s):

Sexual Abuse ◽

Sexual Intercourse ◽

Adult Population ◽

Population Based ◽

Adult Women ◽

Institutional Settings ◽

General Adult Population ◽

Nature Contact ◽

Protective Strategies ◽

Type Of Institution

The lifetime prevalence of sexual abuse in institutional settings in Germany was examined in a sample representative of the general adult population ( N = 2,437). Participants completed a survey on whether they had ever experienced such abuse, its nature (contact, noncontact, forced sexual, intercourse), the type of institution (e.g. school, club), and the relationship of perpetrator to victim (peer, caregiver, staff member). Overall, 3.1% of adult respondents (women: 4.8%, men: 0.8%) reported having experienced some type of sexual abuse in institutions. Adult women reported higher rates of all types than did men, with rates of 3.9% versus 0.8% for contact sexual abuse, 1.2% versus 0.3% for noncontact sexual abuse, and 1.7% versus 0.2% for forced sexual intercourse. We conclude that a remarkable proportion of the general population experiences sexual abuse in institutions, underscoring the need for development of protective strategies. Especially, schools seem to represent good starting points for primary prevention strategies.

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The four weeks before lockdown during the COVID-19 pandemic in Germany: a weekly serial cross-sectional survey on risk perceptions, knowledge, public trust and behaviour, 3 to 25 March 2020

Eurosurveillance ◽

10.2807/1560-7917.es.2021.26.42.2001900 ◽

2021 ◽

Vol 26 (42) ◽

Author(s):

Cornelia Betsch ◽

Lars Korn ◽

Tanja Burgard ◽

Wolfgang Gaissmaier ◽

Lisa Felgendreff ◽

...

Keyword(s):

Data Collection ◽

Risk Perceptions ◽

Online Survey ◽

Adult Population ◽

Healthcare Sector ◽

Federal State ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Psychological Variables ◽

Trust In Institutions

Background During the COVID-19 pandemic, public perceptions and behaviours have had to adapt rapidly to new risk scenarios and radical behavioural restrictions. Aim To identify major drivers of acceptance of protective behaviours during the 4-week transition from virtually no COVID-19 cases to the nationwide lockdown in Germany (3–25 March 2020). Methods A serial cross-sectional online survey was administered weekly to ca 1,000 unique individuals for four data collection rounds in March 2020 using non-probability quota samples, representative of the German adult population between 18 and 74 years in terms of age × sex and federal state (n = 3,910). Acceptance of restrictions was regressed on sociodemographic variables, time and psychological variables, e.g. trust, risk perceptions, self-efficacy. Extraction of homogenous clusters was based on knowledge and behaviour. Results Acceptance of restrictive policies increased with participants’ age and employment in the healthcare sector; cognitive and particularly affective risk perceptions were further significant predictors. Acceptance increased over time, as trust in institutions became more relevant and trust in media became less relevant. The cluster analysis further indicated that having a higher education increased the gap between knowledge and behaviour. Trust in institutions was related to conversion of knowledge into action. Conclusion Identifying relevant principles that increase acceptance will remain crucial to the development of strategies that help adjust behaviour to control the pandemic, possibly for years to come. Based on our findings, we provide operational recommendations for health authorities regarding data collection, health communication and outreach.

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Association of Dietary and Lifestyle Inflammation Score With Metabolic Syndrome in a Sample of Iranian Adults

Frontiers in Nutrition ◽

10.3389/fnut.2021.735174 ◽

2021 ◽

Vol 8 ◽

Author(s):

Fatemeh Dehghani Firouzabadi ◽

Ahmad Jayedi ◽

Elaheh Asgari ◽

Zahra Akbarzadeh ◽

Nasim Janbozorgi ◽

...

Keyword(s):

Metabolic Syndrome ◽

Adult Population ◽

Positive Association ◽

Population Based ◽

Cross Sectional Study ◽

Significant Positive Association ◽

Cross Sectional ◽

General Adult Population ◽

Education Status ◽

Inflammation Score

Objective: We aimed to evaluate the association between the dietary and lifestyle inflammation score (DLIS) and metabolic syndrome (MetS) and its components in a sample of Iranian adults.Design: Population-based cross-sectional study.Setting: General adult population living in Tehran, Iran.Subjects: We included 827 adult men and women with an age range of 18–59 years who were referred to health centers in different districts of Tehran, Iran. Dietary intake was assessed by a semiquantitative food frequency questionnaire with 168 items. The DLIS was calculated based on four components, including dietary inflammation score, physical activity, cigarette smoking, and general obesity. Higher DLIS represents a more proinflammatory diet and lifestyle. The odds ratio (OR) and 95% confidence interval (CI) of the MetS across quartiles of the DLIS was calculated by using logistic regression analysis, controlling for age, sex, energy intake, marital status, education status, and occupation.Results: A total of 827 participants (31% men) were included, with a mean age of 44.7 ± 10.7 years. The prevalence of the MetS was 30.5%. The DLIS ranged between −2.35 and +3.19 (mean ± SD: 0.54 ± 1.09). There was a significant positive association between the DLIS and odds of MetS (OR fourthvs.thefirstquartile: 1.57, 95% CI: 1.01–2.45) in the fully adjusted model.Conclusion: Our results showed a significant positive association between the DLIS and odds of MetS. The results of the present crosssectional study suggested that having a more proinflammatory lifestyle can be associated with MetS. More prospective studies are needed to confirm the findings.

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The effect of Health Literacy on COVID-19 Vaccine Hesitancy: The Moderating Role of Stress

10.1101/2021.06.16.21258808 ◽

2021 ◽

Author(s):

Fan Zhang ◽

Huiqiao Zhang ◽

Yue Li ◽

Sihui Peng ◽

Yue Jiang ◽

...

Keyword(s):

Health Literacy ◽

Online Survey ◽

High Stress ◽

Vaccine Hesitancy ◽

The People ◽

Different Populations ◽

Promotion Strategies ◽

High Level ◽

Moderating Role

Abstract Background The COVID-19 vaccine is an essential means to establish group immunity and prevent the spread of the pandemic. However, the public's hesitation has created major difficulties to the promotion of the vaccine. By investigating the relationship between health literacy and COVID-19 vaccine hesitancy, as well as the potential moderating role of stress, the present study would provide critical insights for tailoring vaccine-promotion strategies. Objective The two-fold research purpose is: i) address the effect of health literacy on people's attitude toward COVID-19 vaccine, ii) clarify the role of stress in this effect. Method With structured questionnaires, an online survey was conducted to evaluate general public's COVID-19 vaccine hesitancy, health literacy, and perceived stress. In total, 560 responses were collected, and moderated regression analysis was conducted to test the effect of health literacy on vaccine hesitancy among people with different levels of stress. Results A total of 560 participants aged over 18 years were included in this study. About 39.8% of the respondents reported vaccine hesitancy, and this rate is higher among those aged 20-30 years old (83%) and female (71.3%). The results showed people with higher level of health literacy are less likely to have vaccine hesitancy . However, this effect was only among those with lower to moderate level of stress , among the people with high stress, no significant effect of health literacy was found . Conclusions By focusing on the effect of health literacy on COVID-19 vaccine hesitancy, the findings showed education program increasing individual's health literacy may also effectively reduce the public's vaccine hesitancy and promote accepting attitude. However, for people with high level of stress, other health programs need to be developed to enhance their positive attitude toward the COVID-19 vaccine. In conclusion, promotion strategies should be tailored for different populations, with considering individual factors such as health literacy and stress. Keywords vaccine hesitancy; health literacy; stress; moderation

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DETERMINANTS OF COVID-19 VACCINE ACCEPTANCE AMONG THE GENERAL ADULT POPULATION IN CHENNAI – A CROSS SECTIONAL SURVEY

10.36106/gjra/3908527 ◽

2021 ◽

pp. 12-14

Author(s):

Monica Kalyanaraman ◽

Parameswari Srijayanth ◽

Srinivas Govindarajulu

Keyword(s):

Public Perception ◽

Online Survey ◽

Adult Population ◽

Vaccine Hesitancy ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Vaccine Acceptance ◽

Total N ◽

Study Objective ◽

The People

Background: Coronavirus outbreak was a highly unpredicted global burden that caused millions of deaths across the world. Vaccination against the infection declines the morbidity and mortality rates. This study objective aims to determine the reasons for the vaccine acceptance. Methods: A cross sectional study was conducted through an online survey among the people living in chennai, Tamilnadu. An E-survey Google forms are circulated through the social platforms and email. Excluding the non-response all the data gained was descriptively analyzed. Results: Out of total (n =376 ≥ 18 years) participants majority of them showed High acceptance and got already vaccinated whereas some revealed the fear of vaccine safety and risk effects. Vaccine hesitancy is seen in terms of lack of trust and proper awareness, myths about adverse effects. In addition our ndings positively convey the knowledge of effective preventive measures for infection and proper following of government guidelines. Conclusion: The study outcomes even though shows willingness of the people in receiving the vaccine at some point still a notable interruption is seen. Prioritization should be given to those critical areas to inuence the public perception about vaccine benets because now vaccination is the only essential measure to suppress the healthcare pressure which halts the covid 19 infection.

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Predicting COVID-19 Vaccination Intention: The Determinants of Vaccine Hesitancy

Vaccines ◽

10.3390/vaccines9101161 ◽

2021 ◽

Vol 9 (10) ◽

pp. 1161

Author(s):

Nuno Fernandes ◽

Daniela Costa ◽

Diogo Costa ◽

José Keating ◽

Joana Arantes

Keyword(s):

Psychological Factors ◽

Online Survey ◽

Herd Immunity ◽

Personal Characteristics ◽

Policy Decision ◽

Vaccine Hesitancy ◽

Attitudes And Beliefs ◽

Linear Regression Models ◽

Domain Specific ◽

Main Determinants

Do people want to be vaccinated against COVID-19? Herd immunity is dependent on individuals’ willingness to be vaccinated since vaccination is not mandatory. Our main goal was to investigate people’s intention to be vaccinated and their intentions to vaccinate their children. Moreover, we were interested in understanding the role of the personal characteristics, psychological factors, and the lockdown context on that decision. Therefore, we conducted an online survey during the lockdown in Portugal (15 January 2021 until 14 March 2021). Participants completed a socio-demographic questionnaire, questions about their intentions of being vaccinated, concerns about the vaccine, a COVID-19 attitudes and beliefs scale, a COVID-19 vaccine attitudes and beliefs scale, and the Domain-Specific Risk-Taking (DOSPERT) Scale. Our results showed that from the 649 participants, 63% of the participants reported being very likely to have the vaccine, while 60% reported being very likely to vaccinate their children. We conducted two linear regression models, explaining 65% of the variance for personal vaccination and 56% of the variance for children vaccination. We found that the COVID-19 vaccine general beliefs and attitudes were the main determinants of vaccination intention. Additionally, our proposed artificial neural network model was able to predict with 85% accuracy vaccination intention. Thus, our results suggest that psychological factors are an essential determinant of vaccination intention. Thus, public policy decision makers may use these insights for predicting vaccine hesitancy and designing effective vaccination communication strategies.

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Risk, Trust, and Flawed Assumptions: Vaccine Hesitancy During the COVID-19 Pandemic

10.31234/osf.io/57pwf ◽

2021 ◽

Author(s):

Omid V. Ebrahimi ◽

Miriam S. Johnson ◽

Sara Ebling ◽

Ole Myklebust Amundsen ◽

Øyvind Halsøy ◽

...

Keyword(s):

Perceived Risk ◽

Online Survey ◽

Viral Infections ◽

Adult Population ◽

Age Groups ◽

Sociodemographic Factors ◽

World Health ◽

Vaccine Hesitancy ◽

Natural Immunity ◽

Factors Associated

Background: The pace at which the present pandemic and future public health crises involving viral infections are eradicated heavily depends on the availability and routine implementation of vaccines. This process is further affected by a willingness to vaccinate, embedded in the phenomenon of vaccine hesitancy. The World Health Organization has listed vaccine hesitancy among the greatest threats to global health, calling for research to identify the factors associated with this phenomenon. Methods: The present study seeks to investigate the psychological, contextual, and sociodemographic factors associated with vaccination hesitancy in a large sample of the adult population. 4571 Norwegian adults were recruited through an online survey between January 23 to February 2, 2021. Subgroup analyses and multiple logistic regression was utilized to identify the covariates of vaccine hesitancy. Results: Several subgroups hesitant toward vaccination were identified, including males, rural residents, and parents with children below 18 years of age. No differences were found between natives and non-natives, across education or age groups. Individuals preferring unmonitored media platforms (e.g., information from peers, social media, online forums, and blogs) more frequently reported hesitance towards vaccination than those relying on information obtainment from source-verified platforms. Perceived risk of vaccination, belief in the superiority of natural immunity, fear concerning significant others being infected by the virus, and trust in health officials’ dissemination of vaccine-related information were identified as key variables related to vaccine hesitancy. Conclusions: Given the heterogeneous range of variables associated with vaccine hesitancy, additional strategies to eradicate vaccination fears are called for aside from campaigns targeting the spread of false information. Responding to affective reactions in addition to involving other community leaders besides government and health officials present promising approaches that may aid in combating vaccination hesitation.

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Prevalence and Correlates of Individuals Screening Positive for Depression and Anxiety on the PHQ-4 in the German General Population: Findings from the Nationally Representative German Socio-Economic Panel (GSOEP)

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph17217865 ◽

2020 ◽

Vol 17 (21) ◽

pp. 7865

Author(s):

André Hajek ◽

Hans-Helmut König

Keyword(s):

Chronic Diseases ◽

Adult Population ◽

Population Based ◽

Depression And Anxiety ◽

Cross Sectional ◽

Self Rated Health ◽

Patient Health ◽

General Adult Population ◽

Nationally Representative ◽

Probable Depression

Our aim was to estimate the prevalence and correlates of probable depression and anxiety in the general adult population in Germany. Repeated cross-sectional data (i.e., cross-sectional data observed at different time points: year 2012 and year 2014) were derived from the innovation sample of the German Socio-Economic Panel, a population-based study of German households. The validated Patient Health Questionnaire (PHQ-4) was used to measure probable depression and anxiety. In the analytical sample, n equaled 2952 individuals. According to the PHQ-4 cut-off values, 10.4% of the individuals had probable depression and 9.8% of the individuals had probable anxiety. Regressions revealed that the likelihood of depression was positively associated with lower age (OR: 0.98 (95% CI: 0.98–0.99)), being unmarried (and living together with spouse) (OR: 0.75 (0.58–0.98)), worse self-rated health (OR: 1.99 (1.73–2.27)), and more chronic diseases (OR: 1.18 (1.07–1.31)). Furthermore, the likelihood of anxiety was positively associated with being female (OR: 1.36 (95% CI: 1.04–1.76)), lower age (OR: 0.98 (95% CI: 0.97–0.99)), low education (medium education, OR: 0.69 (0.50–0.95)), worse self-rated health (OR: 2.00 (1.74–2.30)), and more chronic diseases (OR: 1.15 (1.03–1.27)). The magnitude of depression and anxiety was highlighted. Clinicians should be aware of the factors associated with probable depression and anxiety.

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