scholarly journals The effects of binge-pattern alcohol consumption on orthodontic tooth movement

2014 ◽  
Vol 19 (6) ◽  
pp. 93-98 ◽  
Author(s):  
Cristiano Miranda de Araujo ◽  
Aline Cristina Batista Rodrigues Johann ◽  
Elisa Souza Camargo ◽  
Orlando Motohiro Tanaka
Keyword(s):  
Bone Resorption ◽  
Saline Solution ◽  
Tooth Movement ◽  
Orthodontic Tooth Movement ◽  
Control Group ◽  
Tartrate Resistant Acid Phosphatase ◽  
Chi Square ◽  
Significance Level ◽  
Male Wistar Rats ◽  
Chi Square Test

OBJECTIVE: This study aimed to assess tissue changes during orthodontic movement after binge-pattern ethanol 20% exposure.METHODS: Male Wistar rats (n = 54) were divided into two groups. The control group (CG) received 0.9% saline solution, while the experimental group (EG) received 20% ethanol in 0.9% saline solution (3 g/kg/day). On the 30th day, a force of 25 cN was applied with a nickel-titanium closed coil spring to move the maxillary right first molar mesially. The groups were further divided into three subgroups (2, 14 and 28 days). Tartrate-resistant acid phosphatase and picrosirius were used to assess bone resorption and neoformation, respectively. Data were compared by two-way ANOVA, Tukey's HSD, Games-Howell and chi-square test. Significance level was set at 5%.RESULTS: There was a decrease in the number of osteoclasts in EG at day 28. The percentage of collagen showed no interaction between group and time.CONCLUSION: Binge-pattern 20% ethanol promoted less bone resorption at the end of tooth movement, thereby suggesting delay in tooth movement.

scholarly journals The effect of alveolar decortication on orthodontically induced root resorption

2020 ◽  
Vol 90 (4) ◽  
pp. 524-531 ◽  
Author(s):  
Po-Jung Chen ◽  
Joy H. Chang ◽  
Eliane H. Dutra ◽  
Ahmad Ahmida ◽  
Ravindra Nanda ◽  
...  
Keyword(s):  
Tooth Movement ◽  
Root Resorption ◽  
Orthodontic Tooth Movement ◽  
Control Group ◽  
Tartrate Resistant Acid Phosphatase ◽  
Micro Computed Tomography ◽  
Root Volume ◽  
Male Wistar Rats ◽  
Group 3 ◽  
Group 2

ABSTRACT Objective To determine the effect of alveolar decortication on orthodontically induced root resorption. Materials and Methods A total of 24 male Wistar rats (14 week old) were used. The rats were randomly divided into one of the following three groups: group 1 (control group), orthodontic tooth movement (OTM) for 2 weeks; group 2, OTM for 2 weeks + two alveolar decortications (2AD); group 3, OTM for 2 weeks + four alveolar decortications (4AD). The first molar was moved mesially for 2 weeks. Micro computed tomography was used to analyze root volume. In addition, histological sections were stained with Tartrate Resistant Acid Phosphatase (TRAP) to quantify the osteoclast number. Results The buccal root volume in OTM + 4AD group was decreased by 8.92% and 6.11% when compared with the OTM-only group and OTM + 2AD group, respectively. Similarly, the other four root volumes in the OTM + 4AD group was decreased by 8.99% and 5.24% when compared with the OTM-only group and OTM + 2AD group, respectively. There was a decrease in buccal root density in the OTM + 4AD group by 4.66% and 3.56% when compared with the OTM-only group and the OTM + 2AD group, respectively. In addition, there was an increase in the number of osteoclasts by 195.73% and 98.74% in OTM + 4AD group in comparison with the OTM and OTM + 2AD group. Conclusions The amount of orthodontically induced root resorption was positively correlated with the extent of surgical injury used to accelerate orthodontic tooth movement.

Resorbable Collagen Barrier Impeding the Extrusion of Obturating Material in Primary Molars Undergoing Resorption – A Randomized Clinical Trial

2021 ◽  
Vol 45 (5) ◽  
pp. 312-316
Author(s):  
Mishra Neha Sanjeev ◽  
Harsimran Kaur ◽  
Sandeep Singh Mayall ◽  
Rishika ◽  
Ramakrishna Yeluri
Keyword(s):  
Test Group ◽  
Primary Molars ◽  
Control Group ◽  
Chi Square ◽  
Significance Level ◽  
Significant Difference ◽  
Chi Square Test ◽  
Group A ◽  
Group B ◽  
And Control

Objective: To evaluate the effectiveness of placing a resorbable collagen barrier in impeding the extrusion of obturation material in primary molars undergoing resorption. Study design: All the 94 canals in 47 mandibular molars were allocated to 2 groups- Group ‘A’- 47 canals with collagen barrier (Test group) and Group ‘B’- 47 canals without collagen barrier (Control group) based on randomization protocol. Pulpectomy was performed and obturation of both test and control canals were radiographically assessed. Pearson’s chi – square test was applied to analyze the results. The significance level was predetermined at p < 0.05. Results: Among the test group, 93.6% of the canals showed no extrusion while, 6.4% showed visible extrusion of the material outside the apex. In the control group, 83% showed no extrusion whereas 17% of the canals showed visible extrusion outside the apex. But no significant difference was noted (p>0.05). Conclusion: The placement of resorbable collagen barrier in the apical third of the canal prevented the extrusion of obturating material beyond the apex in resorbing primary molars.

scholarly journals The Administration of 4-Hexylresorcinol Accelerates Orthodontic Tooth Movement and Increases the Expression Level of Bone Turnover Markers in Ovariectomized Rats

2020 ◽  
Vol 21 (4) ◽  
pp. 1526 ◽  
Author(s):  
Kwang-Hyo Choi ◽  
Dae-Won Kim ◽  
Suk Keun Lee ◽  
Seong-Gon Kim ◽  
Tae-Woo Kim
Keyword(s):  
Tooth Movement ◽  
Orthodontic Tooth Movement ◽  
Ovariectomized Rats ◽  
Control Group ◽  
Tartrate Resistant Acid Phosphatase ◽  
Sprague Dawley ◽  
Osteogenic Markers ◽  
Surgical Methods ◽  
Elevated Expression ◽  
Turnover Markers

Surgical methods for accelerating orthodontic tooth movement are limited by possible damage to the tooth root and patient discomfort. 4-Hexylresorcinol (4HR) has been shown to increase bone remodeling and may potentially facilitate tooth movement. This study investigated the (1) effect of 4HR administration on osteoblast-like cells and (2) effect of 4HR administration on tooth movement in ovariectomized rats. Saos-2 cells were treated with either 4HR or solvent (control). Protein expression levels were investigated 2, 8, and 24 h after treatment. Thirty ovariectomized Sprague-Dawley rats were divided into two experimental groups (A and B) and one control group. After installation of an orthodontic tooth movement device, groups A and B received subcutaneous weekly injections of 4HR (1.28 and 128 mg/kg). Micro-computerized tomography and histological analyses were performed after 2 weeks of tooth movement. The application of 4HR elevated expression of osteogenic markers in Saos-2 cells. Movement of the first molars was significantly greater in rats administered 4HR. Furthermore, the expression of bone morphogenic protein-2, receptor activator of nuclear factor kappa-B ligand, osteocalcin, and tartrate-resistant acid phosphatase were increased after 4HR administration. 4HR application demonstrated increased expression of osteogenic markers in Saos-2 cells and accelerated orthodontic tooth movement in rats.

scholarly journals Toxicology of Lapachol in rats: embryolethality

2001 ◽  
Vol 61 (1) ◽  
pp. 171-174 ◽  
Author(s):  
M. de O. GUERRA ◽  
A. S. B. MAZONI ◽  
M. A. F. BRANDÃO ◽  
V. M. PETERS
Keyword(s):  
Therapeutic Potential ◽  
Treated Group ◽  
Vehicle Group ◽  
Control Group ◽  
Corpora Lutea ◽  
Water Control ◽  
Chi Square ◽  
Significance Level ◽  
Chi Square Test ◽  
Teratogenic Potential

Lapachol is a naphtoquinone with therapeutic potential against enterovirus, Chagas disease and is also used as an antimalarial and antiinflamatory agent. In order to study teratogenic potential of Lapachol, pregnant Wistar rats were treated with 0.5 ml of distilled water (control group); 0.5 ml of hydroalcoholic solution (vehicle group) and 10 mg of Lapachol in 0.5 ml of hydroalcoholic solution (treated group) by oral gavage from the 8th to the 12th day of pregnancy. The following variables were observed: maternal body weight on days 1, 6, l5 and 21 and food intake on days 2, 6, 15 and 21 of pregnancy. The number of live and dead fetuses and the sites of resorptions were counted. The ovaries were weighed and the corpora lutea were counted. Data were analyzed by ANOVA-one way, Dunnett test and the chi square test. Significance level test alpha = 0.05. Results have shown that mothers were unaffected but there were a 99.2% of fetus mortality, indicative of a strong abortifacient effect of Lapachol in rats.

scholarly journals Study of Hyperbaric Oxygen Theraphy and Gold sea Cucumber (Stichopus Hermanii) 3% for Collagen Density of Rat’s with Diabetes Mellitus Induced by Porphyromonas Gingivalis Bactery

DENTA ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 73
Author(s):  
Dyah Lestarining R ◽  
Dian Mulawarmanti ◽  
Widyastuti Widyastuti
Keyword(s):  
Hyperbaric Oxygen ◽  
Periodontal Ligament ◽  
Healing Process ◽  
Control Group ◽  
Therapeutic Effects ◽  
Chi Square ◽  
Significance Level ◽  
Male Wistar Rats ◽  
Collagen Density ◽  
Ligament Healing

<p><strong><em>Background:</em></strong><em> Periodontitis is complication of DM in chronic state. Periodontitis susceptibility increase threefold in patient DM compared non-DM. Debridement with SRP alone is less effective in DM</em><em>. Hyperbaric Oxygen Therapy (HBO) has the effect of increasing insulin sensitivity and synthesis of collagen. Collagen is the largest extracellular matrix supporting periodontal tissue. Stchopus hermanii contains condrotin sulfate serves to inhibit the formation of mixed periodontopatogen bacteri. <strong>Purpose:</strong> To determine the therapeutic effects of  HBO 2,4 ATA 3x3’ interval 5’ 7 days and stichopus hermanii against periodontal ligament collagen density in the healing process of periodontitis with DM. <strong>Materials and Methods:</strong></em><em>The experiment design is factorial design. Rats are inducted with STZ 65 mg/kgBB to make them suffer DM and are inducted with P.gingivalis </em><em>1x10<sup>9</sup>sel/ml for 5 days straight to make them suffer periodontitis</em><em>,</em><em> 20 male Wistar rats were divided into 4 groups. K0 (control group), K1(STZ+P. gingivalis), K2(STZ+P. gingivalis+Stichopus hermanii), K3(STZ+P. gingivalis+HBO), and K4(STZ+P.gingivalis+stichopus hermanii HBO) after treatment on day 52, all groups were sacrificed and done making preparations for the HPA of the mandible bone. <strong>Results:</strong> Data were analyzed using chi-square, Kruskal wallis, and Mann Whitney U with 95% significance level (p = 0.05). increase level of collagen significantly</em> K1<em>(1 ± 0.00)</em> - K2<em>(2±0.00)</em>, dan K1<em>(1 ± 0.00)</em> - K4<em>(2.5 ± 0.289)</em><em>.<strong>Conclution</strong></em><strong><em>:</em></strong><em>Therapy  HBO combination of 2.4 ATA 3 x 30 </em><em>with 5 minutes air breaks for 7 days</em><em> and gel Stichopus hermanii3% effective on the Densityof collagen in the periodontal ligament healing process periodontitis with DM. <br /> <br /> </em></p><p><strong><em>Keywords:</em></strong><em>OHB, Stichopus hermanii, periodontitis with DM, collagen</em></p><p><strong><em> </em></strong></p><strong><em>Correspondence: </em></strong><em>Dian Mulawarmanti, Department of Oral Biology, Faculty of Dentistry, Hang Tuah University,Arif Rahman Hakim 150, Surabaya,Phone 031-5945864, Email: </em><a href="mailto:[email protected]"><em>[email protected]</em></a>

scholarly journals Raloxifene administration enhances retention in an orthodontic relapse model

2020 ◽  
Vol 42 (4) ◽  
pp. 371-377
Author(s):  
Niloufar Azami ◽  
Po-Jung Chen ◽  
Shivam Mehta ◽  
Zana Kalajzic ◽  
Eliane H Dutra ◽  
...  
Keyword(s):  
Alveolar Bone ◽  
Tooth Movement ◽  
Volume Fraction ◽  
Orthodontic Tooth Movement ◽  
Bone Volume ◽  
Resin Cement ◽  
Control Group ◽  
Tartrate Resistant Acid Phosphatase ◽  
Bone Volume Fraction ◽  
Tissue Density

Abstract Background and objectives Orthodontic relapse is a physiologic process that involves remodelling of the alveolar bone and principle periodontal ligament fibres. Raloxifene is an Food and Drug Administration (FDA)-approved selective oestrogen receptor modulator that inhibits systemic bone loss. In our study, we examined the effects of Raloxifene on alveolar bone modelling and orthodontic relapse in a rodent model. Materials and methods The efficacy of raloxifene was evaluated in 15-week-old male Wistar rats, 8 in each group (Control, Raloxifene, Raloxifene + 7-day relapse, Raloxifene + 14-day relapse) for a total of 42 days. All animals had 14 days of orthodontic tooth movement with a closed nickel–titanium coil spring tied from incisors to right first molar applying 5–8 gm of force. On the day of appliance removal, impression was taken with silicon material and the distance between first molar and second molar was filled with light-cured adhesive resin cement for retention phase. Raloxifene Retention, Raloxifene Retention + 7D, Raloxifene Retention + 14D groups received 14 daily doses of raloxifene (2.0 mg/kg/day) subcutaneously after orthodontic tooth movement during retention. After 14 days of retention, the retainer was removed and right first molar was allowed to relapse for a period of 14 days. Raloxifene injection continued for the Raloxifene + 14-day relapse group during relapse phase too. Control group received saline injections during retention. Animals were euthanized by CO2 inhalation. The outcome measure included percentage of relapse, bone volume fraction, tissue density, and histology analysis using tartrate-resistant acid phosphatase staining and determining receptor activator of nuclear factor-кB-ligand (RANKL) and osteoprotegerin expression. Results Raloxifene Retention + 14D group had significantly less (P &lt; 0.05) orthodontic relapse when compared with other groups. There was a significant increase (P &lt; 0.05) in bone volume fraction and tissue density in the Raloxifene Retention + 14D group when compared with other groups. Similarly, there was significant decrease in number of osteoclasts and RANKL expression in Raloxifene Retention + 14D group when compared with Raloxifene Retention + 7D group (P &lt; 0.05). Conclusion Raloxifene could decrease post-orthodontic treatment relapse by decreasing bone resorption and indirectly enhancing bone formation.

scholarly journals Development Of Strategic Methods For Family Balanced Counseling (SKB KB) On The Selection Of Potential Acceptance Contraception Tools In Makassar

2021 ◽  
Vol 2 (4) ◽  
pp. 1340-1345
Author(s):  
Sitti Mukarramah ◽  
Indriani ◽  
Zulaeha A. Amdadi
Keyword(s):  
Family Planning ◽  
Community Health Center ◽  
Intervention Group ◽  
Control Group ◽  
Chi Square ◽  
Significance Level ◽  
Before And After ◽  
Quasi Experimental ◽  
Chi Square Test ◽  
Counseling Strategy

Family planning is a strategy to reduce maternal mortality, especially mothers with 4T conditions. Counseling plays an important role in achieving quality family planning services. A balanced counseling strategy (SKB) began to be developed and adapted for use in 2016, to strengthen postpartum family planning counseling services (KBPP). The purpose of this study was to determine the effect of the Family Planning Balanced Counseling Strategy (SKB-KB) on the choice of contraceptives at Kassi-Kassi Community Health Center Makassar City. The type of research used is Quasi Experimental (quasi-experimental). This study conducted an intervention in both groups by assessing before and after treatment / counseling. One group intervened with the SKB-KB method, while the other group intervened with the ABPK method. Data were analyzed using the chi square test with a significance level of p <0.05. The results showed that the SKB-KB method had an influence on the choice of contraceptives between the intervention group and the control group (p: 0.0008; α 0.05).

scholarly journals The role of active ingredients nanopowder Stichopus hermanii gel to bone resorption in tension area of orthodontic tooth movement

2017 ◽  
Vol 50 (4) ◽  
pp. 188
Author(s):  
Noengki Prameswari ◽  
Arya Brahmanta
Keyword(s):  
Bone Resorption ◽  
Alveolar Bone ◽  
Tooth Movement ◽  
Chondroitin Sulphate ◽  
Orthodontic Tooth Movement ◽  
Negative Control Group ◽  
Positive Control ◽  
Negative Control ◽  
Control Group ◽  
Active Ingredients

Background: Orthodontic tooth movement is a continual and balanced process between bone deposition and bone resorption in pressure and tension sites. Stichopus hermanii is one of the best fishery commodities in Indonesia. It is natural and contains various active ingredients such as hyaluronic acid, chondroitin sulphate, cell growth factor, eicosa pentaenoic acid (EPA) docosa hexaenoic acid (DHA) and flavonoid that potentially play a role in orthodontic tooth movement. Purpose: The aim of this study was to investigate the active ingredients of nanopowder Stichopus hermanii promoting bone resorption in tension area orthodontic tooth movement. Methods: A quantitative test for active ingredients of stichopus hermanii was conducted. Thirty two male Cavia cobaya were divisibled became four groups. K (–) groups as a negative control group (without treatment), K (+) groups as a positive control group which were provided with a separator rubber for orthodontic tooth movement, and P1, P2 groups, which were treated with 3% and 3.5% stichopus hermanii for orthodontic tooth movement. After treatment the cavia cobaya were sacrificed. TRAP-6 expression as a osteoclast marker was examined by means of an immunohistochemistry method. Results: A one-way Anova test confirmed that TRAP-6 expression was significantly increased with p = 0.00 (p≤0,05) in P2 compared to K (+). P2 to K (–), P2 to P1 and P1 to K (+) had no significant differences Conclusion: Nanopowder Stichopus hermanii 3.5% has an active ingredient that could increase osteoclast activity to resorb periodontal ligament and alveolar bone in tension areas of orthodontic tooth movement.

scholarly journals The effect of the extent of surgical insult on orthodontic tooth movement

2019 ◽  
Vol 41 (6) ◽  
pp. 601-608 ◽  
Author(s):  
Joy Chang ◽  
Po-Jung Chen ◽  
Eliane H Dutra ◽  
Ravindra Nanda ◽  
Sumit Yadav
Keyword(s):  
Wistar Rats ◽  
Alveolar Bone ◽  
Tooth Movement ◽  
Orthodontic Tooth Movement ◽  
Primary Objective ◽  
Bone Volume ◽  
Tartrate Resistant Acid Phosphatase ◽  
Trabecular Thickness ◽  
Tissue Density ◽  
Male Wistar Rats

Abstract Objective The primary objective of this study was to investigate how the extent of surgical insult affects the orthodontic tooth movement (OTM) and the alveolar bone modelling and remodelling in a rodent model. Material and methods 15-week-old male Wistar rats were used in the research and they were randomly divided into three treatment groups: (1) OTM only (N = 8); (2) OTM + 2 alveolar decortication (AD) (less surgical insult) (N = 8); and (3) OTM + 4 AD (more surgical insult) (N = 8). A nickel-titanium spring delivering 5–8 g of force was used to protract the molar mesially using maxillary incisors as an anchorage. AD was done using a hand piece and a round bur, adjacent to the left first maxillary molar on the palatal alveolar bone. After 14 days of OTM Wistar rats were killed and microfocus computed tomography and histological analysis were performed. Results The OTM + 4AD group presented with a significant increase (P &lt; 0.05) in the rate of tooth movement when compared to OTM + 2AD group and OTM only group. In addition, the OTM + 4AD group had a significant decrease in bone volume and tissue density (P &lt; 0.05) and a significant increase (P &lt; 0.05) in the trabecular spacing and trabecular thickness when compared to OTM only. Histological quantification of tartrate-resistant acid phosphatase indicated a significant percent increase (P &lt; 0.05) in OTM + 4AD group, when compared to OTM + 2AD and OTM only group. Results Increased surgical insult increases the rate of OTM. Additionally, increased surgical insult decreases the bone volume and the tissue density.

scholarly journals SKELETAL AND DENTAL CHANGES INDUCED BY BIONATOR IN EARLY TREATMENT OF CLASS II

2016 ◽  
Vol 38 (2) ◽  
pp. 205
Author(s):  
Dirceu Barnabé Raveli ◽  
João Paulo Schwartz ◽  
Taísa Boamorte Raveli ◽  
Ary Dos Santos Pinto ◽  
Bryan Tompson
Keyword(s):  
Early Treatment ◽  
Treatment Time ◽  
Class Ii ◽  
Treated Group ◽  
Control Group ◽  
Differential Growth ◽  
Chi Square ◽  
Significance Level ◽  
Chi Square Test ◽  
Student’S T

The purpose was to investigate the amount of skeletal and dentoalveolar changes after early treatment of Class II, Division 1 malocclusion with bionator appliance in prepubertal growing patients. Forty Class II patients were divided in two groups. Treated group consisted of 20 subjects treated consecutively with bionator. Mean age at the start of treatment (T0) was 9.1 years, while it was 10.6 years at the end of treatment (T1). Mean treatment time was 17.7 months. Pretreatment and post-treatment cephalometric records of treated group were evaluated and compared with a control group consisted of 20 patients with untreated Class II malocclusion. Intergroup comparisons were performed using Student’s t-tests and chi-square test with Yates’ correction at a significance level of 5 per cent. Bionator appliance was effective in generating differential growth between the jaws. Cephalometric skeletal measurements ANB, WITS, Lafh, Co-A and dental L6-Mp, U1.Pp, IsIi, OB, OJ showed statistically significantly different from the control. Bionator induced more dentoalveolar changes than skeletal during treatment in prepubertal stage. 

Sign in / Sign up

Export Citation Format

Share Document