scholarly journals ANTI-TTG AMONG CHILDREN WITH CHRONIC FUNCTIONAL CONSTIPATION UNRESPONSIVE TO 6 WEEKS OF TREATMENT OF CONSTIPATION

2017 ◽  
Vol 54 (3) ◽  
pp. 197-200 ◽  
Author(s):  
Nooshin SADJADEI ◽  
Samaneh HOSSEINMARDY ◽  
Mehran HAKIMZADEH ◽  
Tahereh ZIAEI KAJBAF ◽  
Hazhir JAVAHERIZADEH
Keyword(s):  
Celiac Disease ◽  
Data Analysis ◽  
Functional Constipation ◽  
Cross Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Appropriate Treatment ◽  
Rome Iii ◽  
F 273

ABSTRACT BACKGROUND Celiac disease is a glutten induced enteropathy. Some authors recommended screening celiac in children with constipation. There are studies to evaluate celiac disease in children with constipation. But most of them included children regardless to treatment failure. OBJECTIVE The aim of this study was to evaluate frequency of elevated anti TTG in children with constipation after failure to improve during 6 week of appropriate treatment of constipation. METHODS In this cross sectional study, 550 children with prolonged constipation were included. Place of study was Pediatric Gastroenterology clinic of Abuzar children’s hospital. Prolonged constipation was defined as a constipation which failed to resolved after 6 weeks of appropriate treatment. Constipation was defined according to ROME III criteria. After parental agreement, 5 mL of blood was obtained. Serum anti TTG level was measure using ELISA method by Orientec kit. Anti TTG>10 was considered positive if IgA was normal. SPSS version 16.0 (Chicago, IL, USA) was used for data analysis. Chi square, t-test, and Mann Whitney test used for data analysis. RESULTS In this study 550 children (m=277, f=273) were included. Mean age of the cases was 6.8±2.9 year. Anti TTG antibody level was 5.8±2.8 unit/mL. Of these case, 42 (7.6%) had positive anti-TTG antibody. Celiac disease was confirmed in 40 cases after histopathology examination. CONCLUSION Anti-TTG was positive in 7.6% children with chronic constipation who failed to respond after 6 week of treatment. Another multicenter study with longer follow up period is recommended.

scholarly journals Female Functional Constipation Is Associated with Overactive Bladder Symptoms and Urinary Incontinence

2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Takahiro Maeda ◽  
Masuomi Tomita ◽  
Atsushi Nakazawa ◽  
Gen Sakai ◽  
Shinsuke Funakoshi ◽  
...  
Keyword(s):  
Urinary Incontinence ◽  
Overactive Bladder ◽  
Functional Constipation ◽  
Cross Sectional Study ◽  
Urinary Symptoms ◽  
Rome Iii Criteria ◽  
Cross Sectional ◽  
Associated Factor ◽  
Female Patients ◽  
Rome Iii

This noninterventional cross-sectional study aims to assess the association between functional constipation (FC) and urinary symptoms in female patients with no treatment for urination and defecation. The Rome III criteria for evaluation of defecation, Overactive Bladder Symptom Score (OABSS) for evaluation of urinary symptoms, and clinical features were investigated in 145 female patients. Latent FC and moderate to severe overactive bladder (OAB) were defined on the basis of positivity for two or more of the Rome III criteria and an OABSS ≥ 6 with OABSS Q3 ≥ 2, respectively. In 60 latent FC patients, the OABSS was higher (5.0 versus 3.2, p=0.001), and concurrent moderate to severe OAB symptoms and OAB with urinary incontinence were more frequent than those in 85 nonlatent FC patients (33.3 versus 10.6%, p=0.001, and 31.7 versus 7.1%, p<0.001). Multivariate analysis demonstrated that moderate to severe OAB symptoms were a significant associated factor of latent FC (odds ratio (OR) = 4.125, p=0.005), while latent FC was the only associated factor of moderate to severe OAB and OAB with urinary incontinence (OR = 4.227, p=0.005 and OR = 4.753, p=0.004). In conclusion, moderate to severe OAB symptoms are correlated with FC. Moreover, FC is related to moderate to severe OAB symptoms and to OAB with urinary incontinence.

scholarly journals Applying ESPGHAN and WGO Guidelines of Celiac Disease on Iraqi Patients

2018 ◽  
Vol 4 (4) ◽  
Keyword(s):  
Celiac Disease ◽  
Challenge Test ◽  
Disease Diagnosis ◽  
Cross Sectional Study ◽  
City Hospital ◽  
Chi Square ◽  
Cross Sectional ◽  
Asymptomatic Patients ◽  
Qualitative Variables ◽  
Chi Square Test

Objective: The goal of the study is to check the degree to which the physicians and pediatricians can apply ESPGHAN and WGO criteria of celiac disease (CD) on their patients in Karbala city. Methods: This is a cross-sectional study conducted in Karbala city hospitals (Al-Hussein-medical city hospital, the pediatric teaching hospital) for the period from August 2017 to February 2018. A random selection of one hundred eight CD patients was carried out and the clinical data including the biopsy results were collected directly from patients or their family members via a questionnaire sheets. Statistically, the quantitative variables were analyzed using non-parametric t-test and the qualitative variables were analyzed using Chi-square test. Results: The study shows that of the total 108 patients, only n=43 (39.8%) of candidates who did biopsy even with tTG IgA>10 fold ULN (200 RU/ml and more) due to the shortage in EMA/HLA tests recommended by ASPGHAN to omit duodenal biopsy., while n=51 (47.2%) accomplished only one of the triple tests (only tTG IgA>10 fold ULN) suggested by ASPGHAN and then applied challenge test and n=14 (12.9) achieved non of the triple tests (tTG IgA antibody titer>5 fold ULN, but <10 fold ULN). On the other hand, the WGO guideline is more suitable if properly applied as it considers tTG (IgA) a convenient substituent of EMA test where high tTG (IgA) serum level being diagnostic and to be confirmed by the available DGP (IgA and IgG) antibodies. Conclusion: The WGO guideline for symptomatic and asymptomatic patients is more applicable for the areas with limited facilities, while ESPGHAN guideline for pediatrics can be applied to a less degree. Generally in Iraq there is a delay in disease diagnosis due to many reasons to be evaluated.

scholarly journals Factors Associated with Basic Immunization Status of Infants

2018 ◽  
Vol 4 (1) ◽  
pp. 32-39
Author(s):  
Dewi Novitasari Suhaid ◽  
Fransisca Faranita
Keyword(s):  
Data Analysis ◽  
Cross Sectional Study ◽  
Education Level ◽  
Dominant Factor ◽  
Primary Immunization ◽  
Chi Square ◽  
Cross Sectional ◽  
Immunization Status ◽  
Chi Square Test ◽  
Knowledge And Attitude

Immunization is an attempt to actively boost a person's immunity against a disease, so that if one day exposed to the disease will not get sick or just experience mild illness. Immunization is routinely divided into primary immunization and continued immunization. Basic immunization is given to infants aged 0 to 1 year, where as advanced immunization is a repeat immunization intended to maintain immunity level or to prolong the period of protection. Further immunization is given when primary immunization is given first, and is given at the age of toddlers and at school age. This research is cross-sectional study. The dependent variable in this study is the basic immunization status of infants, while the independent variables include age, education level, occupation, knowledge and attitude. The sample of this research is mothers with children aged 12-24 months totaling 250 respondents. Instrument of data collection using questionnaire and health record of baby. The data transformation uses the data normality test and Rasch model. Data analysis technique using Chi Square test and logistic regression test. The result of data analysis showed that there was a significant correlation between occupation (p <0,05, PR = 1,864; 95% CI = 1,121-3,097), education level (p <0,05; PR = 3,438; 95% CI = 1,671- 7,074), knowledge (p <0,05, PR = 2,653; 95% CI 1,580-4,455) and attitude (p <0,05, PR = 3,202; 95% CI = 1,897-5,405) with infant immunization status. Age has no significant relationship with the basic immunization status of infants. Conclusions coverage of basic infant immunization completeness in this area is still low that is equal to 42,4%. Attitude is the most dominant factor associated with the basic immunization status of infants.

scholarly journals Implementasi Prinsip Keterbukaan dalam Pemberdayaan Terhadap Keaktifan Kader Kesehatan untuk Mencegah Risiko Kematian Ibu

2019 ◽  
Vol 11 (1) ◽  
pp. 39
Author(s):  
Yuni Romalita ◽  
Yusriani Yusriani ◽  
Muhammad Khidri Alwi ◽  
Serawati Serawati
Keyword(s):  
Public Health ◽  
Data Analysis ◽  
Mortality Rate ◽  
Maternal Death ◽  
Cross Sectional Study ◽  
Questionnaire Data ◽  
Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test

Implementasi Prinsip Keterbukaan dalam Pemberdayaan Terhadap Keaktifan Kader Kesehatan untuk Mencegah Risiko Kematian Ibu Yuni Romalita Program Studi Magister Kesehatan, Pascasarjana Universitas Muslim Indonesia; [email protected] Yusriani Fakultas Kesehatan Masyarakat, Universitas Muslim Indonesia; [email protected] (koresponden) Muhammad Khidri Alwi Fakultas Kesehatan Masyarakat, Universitas Muslim Indonesia; [email protected] Serawati Program Studi Magister Kesehatan, Pascasarjana Universitas Muslim Indonesia; [email protected] ABSTRACT Maternal Mortality Rate (MMR) is one of the important indicators of the degree of public health. One of the government's programs in suppressing MMR is the empowerment of health cadres. Cadres have a big role to play in the smooth process of health services, one of which is posyandu activities. The principle of openness is very important in empowerment to increase the activeness of cadres in reducing MMR. The research objective is to find out the implementation of the principle of openness in empowering the activeness of health cadres in preventing the risk of maternal death in Gowa Regency. This type of research was cross sectional study with a sample size of 120 people, selectied by accidental sampling. Data collection was done by interview using a questionnaire, data analysis using the Chi square test. The results showed that 89.2% of cadres met the principle of openness in empowerment and 10.8% did not meet the principle of openness. There is a relationship between the implementation of the principle of openness in empowerment to the activeness of health cadres in preventing the risk of maternal death in Gowa Regency. It is expected that all relevant parties can work together to increase the activity of health cadres in preventing the risk of maternal death, especially in applying the principle of openness in empowerment. Keywords: the principle of openness; cadre empowerment; maternal death; cadre activity ABSTRAK Angka Kematian Ibu (AKI) menjadi salah satu indikator penting dari derajat kesehatan masyarakat. Salah satu program pemerintah dalam menekan AKI adalah pemberdayaan kader kesehatan. Kader memiliki peran besar terhadap lancarnya proses pelayanan kesehatan salah satunya kegiatan posyandu. Prinsip keterbukaan sangat penting dalam pemberdayaan untuk meningkatkan keaktifan kader dalam menurunkan AKI. Tujuan penelitian yaitu dalam untuk mengetahui implementasi prinsip keterbukaan dalam pemberdayaan terhadap keaktifan kader kesehatan dalam mencegah risiko kematian ibu di Kabupaten Gowa. Jenis penelitian yang digunakan yaitu Cross Sectiona Study dengan jumlah sampel sebanyak 120 orang, pemilihan sampel dengan cara accidental sampling. Pengumpulan data dilakukan dengan wawancara menggunakan kuesioner, analisis data menggunakan uji chi square. Hasil penelitian menunjukkan bahwa 89.2% kader memenuhi prinsip keterbukaan dalam pemberdayaan dan 10.8% yang tidak memenuhi prinsip keterbukaan. Ada hubungan antara implementasi prinsip keterbukaan dalam pemberdayaan terhadap keaktifan kader kesehatan dalam mencegah risiko kematian ibu di Kabupaten Gowa. Diharapkan kepada semua pihak yang terkait dapat bekerja sama untuk meningkatkan keaktifan kader kesehatan dalam mencegah risiko kematian ibu, khususnya dalam menerapkan prinsip keterbukaan dalam pemberdayaan. Kata kunci: prinsip keterbukaan; pemberdayaan kader; kematian ibu; keaktifan kader

Extra-wound fixation: a modified tie-over dressing technique for skin graft

2020 ◽  
Vol 29 (Sup12) ◽  
pp. S23-S27
Author(s):  
Quanmeng Liu ◽  
Xiaodong Liu ◽  
Idy HT Ho ◽  
Shibing Guan
Keyword(s):  
Clinical Outcomes ◽  
Normal Skin ◽  
Skin Grafting ◽  
Cross Sectional Study ◽  
Skin Grafts ◽  
Fixation Technique ◽  
Dressing Method ◽  
Chi Square ◽  
Cross Sectional

Objective: Tie-over dressing is the most frequently used technique of skin grafting. However, many deficiencies affecting the outcome have been reported. We hereby introduce a modified method, termed the ‘extra-wound fixation technique’, for skin dressing, and evaluate the complications and clinical outcomes. Method: In this retrospective cross-sectional study we analysed the medical records of patients treated between January 2012 and December 2017. All patients received full thickness skin grafts. Patients were divided equally into to groups: patients were treated using the extra-wound fixation technique, and the remaining, randomly selected patients treated using the traditional tie-over method. The extra-wound fixation technique uses the traditional tie-over dressing method followed by additional stitches made in healthy skin locating 0.5-1.0 cm laterally to the wound edge. The follow-up outcomes between the two groups were compared using the Chi-square test. Results: A total of 38 patients took part (19 patients in each group). The follow-up duration was 1–6 months. No raised edges were observed in any of the patients. Prolonged follow-up demonstrated that the grafted skin texture became soft with a thin layer of adipose tissue, and elasticity was gradually improved along with the regeneration of dermoelastic fibre. The colour was similar to the normal skin with a smooth surface. Compared with the traditional method, the extra-wound fixation technique significantly improved the survival of the grafted skin (p=0.008), reduced the risk of laceration of the skin (p=0.001), and eliminated crater rim-like appearances (p=0.020). Conclusion: The extra-wound fixation technique could be used for different skin grafts and improve clinical outcomes compared with the traditional tie-over dressing method.

scholarly journals Functional constipation and posture in defecation

2013 ◽  
Vol 53 (2) ◽  
pp. 104 ◽  
Author(s):  
Fahrul Azmi Tanjung ◽  
Supriatmo Supriatmo ◽  
Atan Baas Sinuhaji ◽  
Hakimi Hakimi
Keyword(s):  
Junior High School ◽  
Functional Constipation ◽  
Cross Sectional Study ◽  
Considerable Proportion ◽  
Sectional Study ◽  
Cross Sectional ◽  
Parents And Children ◽  
Rome Iii ◽  
The Relationship ◽  
Nature Ofthe

Background Functional constipation is often a consequence ofhabitual bowel elimination while sitting on common toilet seats.A considerable proportion of the population with n ormal bowelmovement frequency has difficulty emptying their bowels. Theprincipal cause of this problem may be the obstructive nature ofthe rectoanal angle and its relationship to the posture normallyused in defecation.Objective To assess the relationship between functional constipationwith the posture (sitting vs squatting) during defecationin children.Methods We conducted a cross-sectional study in November2010. Participants aged 12- 15 years were selected consecutivelyfrom a junior high school in Medan . Parents and children filledquestionnaires and were interviewed. Functional constipation wasassessed based on the Rome III criteria.Results Sixty-five students enrolled in the study. There was nostatistically significant diffe rences in subjects' characteristics.T here was a significant correlation between functional constipationwith posture during defecation in children (RR= 0.06, 95%CI0.02 to 0.25; P=0.0001). Functional constipation was more likelyoccured in children with sitting (12/20) th an squatting posture(4/45) during defecation.Conclusion We found th at posture in defecation is correlatedto functional con stipation in children.

scholarly journals A69 MULTIPLE FUNCTIONAL GASTROINTESTINAL DISORDERS IN JORDANIAN CHILDREN, NATIONWIDE STUDY

2020 ◽  
Vol 3 (Supplement_1) ◽  
pp. 82-83
Author(s):  
E Altamimi
Keyword(s):  
Functional Gastrointestinal Disorders ◽  
Functional Constipation ◽  
Arabic Language ◽  
Cross Sectional Study ◽  
Gastrointestinal Disorders ◽  
Rome Iii Criteria ◽  
Cross Sectional ◽  
Funding Agencies ◽  
Rome Iii ◽  
Common Combination

Abstract Background Functional gastrointestinal disorders (FGIDs) are common in children worldwide. Multiple FGIDs might share some etiopathogenesis, which makes finding multiple disorders in a child a possibility. Aims Estimate the prevalence of FGIDs in Jordanian children prospectively, whether as a single or combined disorders. Methods A prospective, cross-sectional study was conducted in 6 cities in Jordan. Children between the ages of 4–18 were recruited. A validated Arabic language questionnaires based on Rome III criteria were filled by the participants if older than 10 years and by the parents if younger than 10 years. Results A total of 1587(79.35%) participants filled the questionnaires. 814 (51.29%) were younger than 10 years. FGIDs was diagnosed in 204 (25.03%) of younger children. In children between (11 and 18), 310 (40%) were diagnosed with FGIDs. In children (4–10 yrs.) who were diagnosed with FGIDs, 15.5 % had two disorders, while 3% had three or more disorders. The most common combination was aerophobia and functional constipation, comprising 22.58% of combined disorders. In children (11–18 yrs.) with FGIDs, 22.27% had two disorders and 7% had three or more disorders. Interestingly, the most common combination was aerophagia and functional constipation also, representing 34% of the combined cases. Conclusions Functional gastrointestinal disorders are common in Jordanian children. Multiple Functional gastrointestinal disorders may coexist. Diagnosis of one disorder should not prevent us from investigating other disorders. Funding Agencies None

scholarly journals Drugs and Constipation in Elderly in Nursing Homes: What Is the Relation?

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Gunvor S. Fosnes ◽  
Stian Lydersen ◽  
Per G. Farup
Keyword(s):  
Nursing Home ◽  
Daily Living ◽  
Anatomical Therapeutic Chemical ◽  
Nursing Home Residents ◽  
Functional Constipation ◽  
Cross Sectional Study ◽  
Anticholinergic Effect ◽  
Activity Of Daily Living ◽  
Cross Sectional ◽  
Rome Iii

Introduction. Constipation is a common adverse drug reaction.Objective. Study associations between drugs and constipation in nursing home residents.Design. Cross-sectional study.Material and Methods. Nursing home residents above 60 years of age were included. Demographics, diet, physical activity, activity of daily living, nutritional status, use of drugs, and diseases were recorded. Constipation was defined as functional constipation or constipation-predominant IBS according to the Rome III criteria and/or regular use of laxatives. Drugs were classified according to the Anatomical-Therapeutic-Chemical Classification System (ATC), and anticholinergic effect was noted.Results. In all, 79 men and 188 women with a mean age of 85.4 (SD 7.1) years were included. The prevalence of constipation was 71.5%. Use of drugs in general, including polypharmacy, was not associated with constipation. Reduced activity of daily living (OR = 0.71, 95% CI : 0.60–0.84,P<0.001),other antidepressants(N06AX) (OR 3.08, 95% CI : 1.09–8.68,P=0.03), andbenzodiazepine derivatives(N05BA) (OR = 2.80, 95% CI : 1.12–7.04,P=0.03) were significantly associated with constipation; drugs with markedly anticholinergic effect (OR = 3.7, 95% CI : 0.78–17.53,P=0.10),natural opium alkaloid(N02AA) (OR = 5.01, 95% CI : 0.95–25.94,P=0.06), andpropionic acid derivatives(M01AE) (OR = 7.00, 95% CI : 0.75–65.08,P=0.09) showed a trend.Conclusion.In elderly with constipation, focus should be on specific groups of drugs and nonpharmacological factors, not on drugs in general.

scholarly journals Efficacy of surgical revision of mesh complications in prolapse and urinary incontinence surgery

2020 ◽  
Author(s):  
Claudia R. Kowalik ◽  
Mariëlle M. E. Lakeman ◽  
Sandra E. Zwolsman ◽  
Jan-Paul W. R. Roovers
Keyword(s):  
Urinary Incontinence ◽  
Revision Surgery ◽  
Patient Characteristics ◽  
Cross Sectional Study ◽  
Individual Characteristics ◽  
Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
The Individual

Abstract Introduction and hypothesis Women with mesh-related complications in prolapse (POP) and stress-urinary incontinence (SUI) surgery may benefit from operative mesh resection to alleviate symptoms. We hypothesized that mesh resection would alleviate symptoms and aimed to evaluate risks and benefits in these women. Methods We carried out a cross-sectional study. Primary outcome was improvement specified as better, unchanged or worsened symptoms after mesh revision surgery. Secondary outcomes were health-related quality of life (HrQol) scores of validated questionnaires, surgical characteristics and physical findings at follow-up visits. Descriptive data were reported with mean and medians. Associations were calculated with Spearman correlation coefficient and chi-square test to determine statistical differences between groups. Results Fifty-nine women who underwent mesh revision surgery between 2009 and 2016 were included. After a median follow-up of 1.7 (IQR: 1.1–2.4) years, 44 women (75%) reported improvement of symptoms. No significant surgical or patient characteristics were identified that could differentiate which patients did or did not experience cure or complications.A trend was observed to better HrQol scores in women who reported overall improvement after mesh revision surgery. Seventeen (29%) women needed a subsequent operation after mesh removal. Conclusions This cross-sectional study shows that mesh revision surgery alleviates symptoms in 75% of women with mesh-related complications. Type of revision surgery and individual characteristics did not seem to matter to the individual chance of cure or complications. These data can facilitate the counseling of women considering mesh revision surgery.

scholarly journals Prevalence of celiac disease in irritable bowel syndrome patients: A single centre experience from a large teaching hospital of Lahore, Pakistan

2021 ◽  
Vol 14 (4) ◽  
pp. 176-179
Author(s):  
Mohammad Ahmed Saifullah ◽  
Amer Ahmad Khan ◽  
Sarmad Zahoor ◽  
Sidra Saif ◽  
Javed Sajjad Hashmi ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Celiac Disease ◽  
Demographic Data ◽  
Positive Association ◽  
Cross Sectional Study ◽  
Military Hospital ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Irritable Bowel

Background: Many studies have been conducted worldwide to evaluate the proportion of patients with Celiac disease (CD) in persons presenting with Irritable Bowel Syndrome (IBS), showing a positive association between the two diseases. However, reports from Pakistan remain scanty. This study aims to find out the prevalence of CD in patients presenting with IBS and to establish the correlation of both diseases. Patients and methods: It was a descriptive cross-sectional study conducted at Combined Military Hospital, Lahore (CMHL) from January 2018 till March 2019. Consecutive, nonprobability sampling was used to include 210 patients of both genders with the age range of 15-65 years fulfilling ROME IV criteria and were not previously diagnosed as CD or CKD or CLD. Demographic data was noted. Serum Anti tTG levels and Duodenal Biopsy from the second part was assessed to diagnose CD. CD was labeled if the disease was present on both serological and Histopathological reports. Data were analyzed by using SPSS version 20. Descriptive statistics were calculated and a Chi-square test was used to compare the outcome variables with P-value < 0.05 as significant. Results: Of 210 enrolled patients, 113 (53, 8%) were male and 97 (46.2%) were female. The mean age of the patients was 28.40 ± 5.06 years. Eight patients (3.8%) were positive for Anti tTg and on histopathological findings suggestive of CD. Seven of 8 were less than 35 years old. Out of 8 positive patients, 6 (75%) were females. However, the p-value was found to be insignificant for age (0.549) and gender (0.096). On stratification with respect to duration of IBS, all 8 patients diagnosed with celiac disease were having symptoms of IBS for less than 12 months (100%) which was significant statistically (7.1% vs 0.0%; p=0.007). Conclusion: The frequency of CD was 3.8% among IBS patients. Considering this percentage of CD in IBS patients s, a high index of suspicion for CD in IBS patients is required,

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