Modification in body weight associated with antiepileptic drugs

Antiepileptic drugs (AED) may cause body weight changes. OBJECTIVE: To evaluate the dietary habits and body weight associated with AED in epileptic patients. METHOD: Sixty-six patients were subjected to two interviews, and had their weight and body mass index calculated and compared at both times, interval between six to eight months. RESULTS: It was observed that 59.1% showed weight gain. The patients who had no weight gain had a greater proportion of individuals who engaged in some form of physical activity. However, of the 45 patients who maintained their initial dietary and medication pattern, 75.6% recorded a weight gain. Weight gain was seen in 66.7% of patients on carbamazepine (n=18), 60% on valproate (n=5), 50% on carbamazepine+clobazam treatment (n=14), and 58.3% of patients on other(s) polytherapy (n=12). CONCLUSION: The patient should be alerted to possible weight gain, and should be advised about dieting and participating in regular physical activity.

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Weight and body mass index increase after switch from tenofovir disoproxil fumarate to tenofovir alafenamide fumarate-containing treatment in an antiretroviral therapy-experienced group

International Journal of STD & AIDS ◽

10.1177/0956462420983699 ◽

2021 ◽

pp. 095646242098369

Author(s):

Michał Łomiak ◽

Jan Stępnicki ◽

Tomasz Mikuła ◽

Alicja Wiercińska-Drapało

Keyword(s):

Body Mass Index ◽

Body Weight ◽

Weight Gain ◽

Antiretroviral Therapy ◽

Body Mass ◽

Tenofovir Disoproxil Fumarate ◽

Weight Changes ◽

Mineral Density ◽

Significant Weight Gain ◽

Tenofovir Alafenamide

Tenofovir alafenamide fumarate (TAF) is an alternative to tenofovir disoproxil fumarate (TDF). Currently, TAF is increasingly being used because of its non-inferior antiviral properties, lower risk of nephrotoxicity, and lower decrease in bone mineral density than TDF. There is growing evidence of unfavorable effects of TAF on weight and body mass index (BMI) in antiretroviral therapy (ART)-experienced patients treated with TAF-based ART. The aim of this study was to evaluate whether switching from TDF-containing to TAF-containing ART is associated with an increase in BMI and body weight in ART-experienced patients. Two study groups were established: 32 patients who switched from TDF to TAF only and 68 patients who switched from TDF to TAF along with changes to other components of the ART regimen. Significant weight gain and BMI increase was observed during the first year after initiation of TAF-containing ART regimens in both groups (mean change +1.91 kg and +0.61 kg/m2 in the first group and +1.50 kg and +0.49 kg/m2 in the second group). During the second year of TAF-based treatment, a sustained trend of body weight and BMI increase was noted only in the second group (mean change +1.46 kg, + 0.46 kg/m2). Analysis of body weight changes in certain subpopulations from the second group (selected based on patients’ baseline characteristics) revealed a significant weight gain within two years after the switch in patients over 50 years old and in those whose ART had lasted longer than 10 years. These findings suggest that a possible impact of TAF on weight gain should be taken into account when selecting ART components, especially in older patients or those with a long history of antiretroviral treatment.

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Dietary Habits and Physical Activity in Young Adults with Inappropriately High Body Mass Index - a Cross-Sectional Study in Medical Students

Medicina Sportiva ◽

10.2478/v10036-007-0015-1 ◽

2007 ◽

Vol 11 (3) ◽

pp. 78-83

Author(s):

Lukasz J. Krzych

Keyword(s):

Physical Activity ◽

Body Mass Index ◽

Young Adults ◽

Medical Students ◽

Body Mass ◽

Dietary Habits ◽

High Body Mass Index ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional

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The impact of COVID-19 quarantine on dietary habits and physical activity in Saudi Arabia: a cross-sectional study

BMC Public Health ◽

10.1186/s12889-021-11540-y ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Manar Abduljalil Bakhsh ◽

Jomana Khawandanah ◽

Rouba Khalil Naaman ◽

Shoug Alashmali

Keyword(s):

Physical Activity ◽

Body Weight ◽

Weight Gain ◽

Dietary Habits ◽

Negative Impact ◽

Adult Population ◽

Cross Sectional Study ◽

Future Health ◽

Cross Sectional ◽

The Impact

Abstract Background The COVID-19 pandemic has forced governments around the world to impose strict hygiene and national lockdown measures, which in turn has changed the dietary and lifestyle habits of the world’s population. Thus, the aim of this study is to evaluate whether dietary and physical activity behaviors of Saudi Arabia’s adult population changed during the COVID-19 quarantine. Methods An electronic questionnaire which assessed changes in body weight, dietary habits, and physical activity of Saudi Arabia’s adult population (n = 2255) during the COVID-19 quarantine was distributed on social media between June and July 2020. To test the differences between changes in dietary and physical activity behaviors in relation to changes in body weight a Chi-square test was used. Results Over 40 and 45% of participants reported eating and snacking more, respectively, which led to weight gain in around 28%. Most participants reported that they consumed home-cooked (73%) and healthy meals (47%), while only 7% reported that they consumed foods from restaurants. Feelings of boredom and emptiness (44%) and the availability of time for preparing meals (40%) were the main reasons for changing dietary habits. Honey (43%) and vitamin C (50%) were the most consumed immune-boosting food and dietary supplement, respectively. COVID-19 also had a negative impact on physical activity, lowering the practice in 52% subjects, which was associated with significant weight gain (p < 0.001). Conclusion Assessing the changes to the population’s dietary habits and physical activity during the lockdown will help predict the outcome of the population’s future health and wellbeing after the pandemic.

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The Trp64Arg Polymorphism of the β3-Adrenergic Receptor Gene Is Not Associated with Body Weight or Body Mass Index in Japanese: A Longitudinal Analysis

The Journal of Clinical Endocrinology & Metabolism ◽

10.1210/jc.2003-030655 ◽

2003 ◽

Vol 88 (12) ◽

pp. 5914-5920 ◽

Cited By ~ 20

Author(s):

Yumi Matsushita ◽

Tetsuji Yokoyama ◽

Nobuo Yoshiike ◽

Yasuhiro Matsumura ◽

Chigusa Date ◽

...

Keyword(s):

Physical Activity ◽

Body Mass Index ◽

Body Weight ◽

Energy Intake ◽

Body Mass ◽

Longitudinal Analysis ◽

Adrenergic Receptor ◽

Cross Sectional ◽

Genotype Frequencies ◽

The Cross

Abstract The β3-adrenergic receptor (ADRB3) is expressed mainly in visceral adipose tissue and is thought to contribute to lipolysis and the delivery of free fatty acids to the portal vein. Although many studies have examined the relationship between the Trp64Arg mutation of ADRB3 and obesity, the results have been inconsistent. We examined the cross-sectional relationship of ADRB3 variants with indexes of obesity, and their longitudinal changes over 10 yr, in men and women, aged 40–69 yr, who were randomly selected from the Japanese rural population. The study considered both dietary energy intake and physical activity levels. Among the 746 participants, the genotype frequencies of the Trp64Trp, Trp64Arg, and Arg64Arg variants were 483, 224, and 39, respectively. The cross-sectional analysis showed no significant differences in height, weight, body mass index, blood pressure, serum total and high density lipoprotein cholesterols, and hemoglobin A1c among the genotype groups even after adjustments for gender, age, smoking, alcohol drinking, physical activity, and energy intake. No significant differences in the weight changes between the genotype groups were evident in the longitudinal analysis. We conclude that the Trp64Arg mutation of ADRB3 has little or no influence on either body weight or body mass index in the general Japanese population.

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Abdominal obesity: prevalence, sociodemographic- and lifestyle-associated factors in adolescents

Journal of Human Growth and Development ◽

10.7322/jhgd.127653 ◽

2017 ◽

Vol 27 (1) ◽

pp. 56 ◽

Cited By ~ 2

Author(s):

Willian R. Tebar ◽

Luiz Carlos M. Vanderlei ◽

Catarina C. Scarabotollo ◽

Edner F. Zanuto ◽

Bruna T. C. Saraiva ◽

...

Keyword(s):

Physical Activity ◽

Body Mass Index ◽

Body Weight ◽

Public Schools ◽

Sedentary Behaviour ◽

Body Mass ◽

Abdominal Obesity ◽

Associated Factors ◽

Statistical Significance ◽

Obesity Prevalence

Objectives: The aim of this study was to determine the prevalence of abdominal obesity and its associated factors among adolescents, independent of confounders. Method: A sample of 14–17-year-old individuals (n=1.231), who were students from Londrina/PR-Brazil public schools, was studied. A questionnaire about physical activity, sedentary behaviour and socioeconomic conditions was applied. Anthropometry was composed of body weight (kg), height (m), body mass index (BMI=kg/m²) and waist circumference (cm). The association of abdominal obesity and independent variables was assessed using the chi-square test and the magnitude of associations was verified using Binary Logistic Regression in an unadjusted model and adjusted for confounders (gender, age, socioeconomic status, physical activity and sedentary behaviour). The confidence interval and statistical significance were set at 95% and 5%, respectively, using SPSS v15.0. Results: The abdominal obesity prevalence was 17.5% (CI = 15.4%–19.6%), and was higher in boys than in girls. Adolescents with abdominal obesity had higher values of body weight, height, body mass index and sedentary behaviour compared to eutrophic individuals. Being male increased the risk of abdominal obesity by 36% in adolescents. This risk was two times higher in those with high levels of sedentary behaviour. Conclusion: Abdominal obesity was significantly associated with gender and high levels of sedentary behaviour, regardless of confounding factors. Lifestyle habits are important modifiable risk factors that can effectively contribute to the reduction of obesity from an early age.

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The Relationship of Perceived Body Image, Body Mass Index and Physical Activity with Weight Status among Students at King Abdulaziz University Hospital

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2021/v33i49b33358 ◽

2021 ◽

pp. 218-227

Author(s):

Futoon S. Alobiri ◽

Roaa A. Alharbi ◽

Mohammed R. Algethami ◽

Raghdah H. Ateeq ◽

Aseel M. Badurayq ◽

...

Keyword(s):

Physical Activity ◽

Body Mass Index ◽

Body Image ◽

Body Weight ◽

Body Mass ◽

Body Satisfaction ◽

Weight Status ◽

Rating Scale ◽

Significant Difference ◽

King Abdulaziz University

Aim: Identify the relation between poor esteem for body image and weight-related behaviors. The results will help increase awareness and improve students’ lifestyles to have a better body image and achieve ideal body weight. Methods: A cross-sectional study was conducted among King Abdulaziz University medical students (n= 460) between July to the end of August 2019. Data was collected using the International physical activity questionnaire (IPAQ), figure rating scale (FRS) and analyzed using SPSS software. Result: The results showed that the average Body Mass Index (BMI) was 24.80 ± 11.89. Participant sex was an important factor influencing the prevalence of obesity; male students were more obese than female students with a significant difference (p<0.001). The level of body satisfaction was also affected by gender. Students in preclinical years were more likely to gain weight more than clinical years students. Conclusion: The results show a significant relationship between body satisfaction and gender (P<0.0001) despite having diverse BMIs. Overweight and obese males and females' participants had the lowest body satisfaction. Females who were too thin and had low BMIs described themselves as normal, while males describe themselves as too thin. Conversely, females with high BMIs described themselves as too fat, while males described themselves as normal. This could be due to different factors. Also, underweight females and males have high body satisfaction, which can lead to dangerous behaviors to maintain low body weight which cause negative health consequences.

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Body Mass Index and Body Weight Perception among a Population of Female Adolescents

Open Access Macedonian Journal of Medical Sciences ◽

10.3889/oamjms.2020.3865 ◽

2020 ◽

Vol 8 (E) ◽

pp. 308-312

Author(s):

Siham Lghoul ◽

Mohamed Loukid ◽

Mohamed Kamal Hilali

Keyword(s):

Body Mass Index ◽

Body Weight ◽

Body Mass ◽

Weight Perception ◽

Normal Weight ◽

Female Adolescents ◽

Weight Changes ◽

Cross Sectional ◽

Body Weight Perception ◽

Physical Changes

BACKGROUND: Adolescence is associated with many physical changes, it is described as a period when body weight changes and is likely to become worrying for many adolescents. AIM: This study aims to evaluate associations between body weight perception and body mass index (BMI) among a population of female adolescents. METHODS: A cross-sectional school-based study was conducted from February to May 2017 among 12–19 years olds adolescents (n = 415) from high and middle school. BMI for age percentiles was calculated using the WHO AnthroPlus. Body weight perception was determined using an anonymous questionnaire. RESULTS: The prevalence of misconception of body weight was 60%. The prevalence of misconception was positively associated with the participants age (p < 0.001), the occurrence of menarche (p < 0.05), the increasing of BMI (p < 0.001), and with habits diet satisfaction (p < 0.05). Overweighed participants and who’s with normal weight were more likely to perceive their weight incorrectly (p < 0.05). Furthermore, approximately 2.9% of participants underestimated their true body weight and 57.1% overestimated their weight. However, all participants with underweight had correctly perceived their body weight. Logistic regression showed that predictor factors of misconception weight were participant’s age and BMI. CONCLUSION: It is recommended to improve healthy programs in schools aimed at preventing body weight perception and eating problems among adolescents.

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Climaterium, food intake and medicines

International Journal of Nutrology ◽

10.1055/s-0040-1704009 ◽

2012 ◽

Vol 05 (03) ◽

pp. 134-138 ◽

Cited By ~ 1

Author(s):

Roberta Deh Souza Santos ◽

Eduarda de Castro Furtado ◽

Flávia Giolo Deh Carvalho ◽

Renata Iannetta ◽

Carla Barbosa Nonino ◽

...

Keyword(s):

Physical Activity ◽

Body Mass Index ◽

Body Weight ◽

Vitamin E ◽

Food Intake ◽

Body Mass ◽

Outpatient Clinic ◽

Nutrient Intake ◽

Medication Prescription ◽

Fiber Consumption

ABSTRACT Background: Polytherapy treatment is a common practice observed among menopausal patients. This study aimed to quantify food intake and medications in climacteric patients living in community. Methods: Eligible patients from Climacteric Outpatient Clinic (HCFMRP/USP) were recruited. The collected data were: food intake records, age, body weight, height, levels of physical activity and medications in use. Results: Eighty women were studied. Their age was 548 years and body mass index 307kg/m2. They had inadequate dietary Fe, K, Mg, Ca, thiamin, pyridoxine, vitamin E, folate and fiber consumption; 62% used 3 or more medications/day among hypotensive, micronutrients and anti-depressants. Conclusion: Climacteric women need special attention regarding nutrient intake and medication prescription.

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