scholarly journals The Trp64Arg Polymorphism of the β3-Adrenergic Receptor Gene Is Not Associated with Body Weight or Body Mass Index in Japanese: A Longitudinal Analysis

2003 ◽  
Vol 88 (12) ◽  
pp. 5914-5920 ◽  
Author(s):  
Yumi Matsushita ◽  
Tetsuji Yokoyama ◽  
Nobuo Yoshiike ◽  
Yasuhiro Matsumura ◽  
Chigusa Date ◽  
...  

Abstract The β3-adrenergic receptor (ADRB3) is expressed mainly in visceral adipose tissue and is thought to contribute to lipolysis and the delivery of free fatty acids to the portal vein. Although many studies have examined the relationship between the Trp64Arg mutation of ADRB3 and obesity, the results have been inconsistent. We examined the cross-sectional relationship of ADRB3 variants with indexes of obesity, and their longitudinal changes over 10 yr, in men and women, aged 40–69 yr, who were randomly selected from the Japanese rural population. The study considered both dietary energy intake and physical activity levels. Among the 746 participants, the genotype frequencies of the Trp64Trp, Trp64Arg, and Arg64Arg variants were 483, 224, and 39, respectively. The cross-sectional analysis showed no significant differences in height, weight, body mass index, blood pressure, serum total and high density lipoprotein cholesterols, and hemoglobin A1c among the genotype groups even after adjustments for gender, age, smoking, alcohol drinking, physical activity, and energy intake. No significant differences in the weight changes between the genotype groups were evident in the longitudinal analysis. We conclude that the Trp64Arg mutation of ADRB3 has little or no influence on either body weight or body mass index in the general Japanese population.

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
I. O. Ernest-Nwoke ◽  
M. O. Ozor ◽  
U. Akpamu ◽  
M. O. Oyakhire

Aim. To study the relationship between body mass index (BMI) and blood pressure (BP) on visual acuity among apparently healthy residents of Ekpoma, Esan West Local Government Area of Edo State, Nigeria. Methodology. This is a cross-sectional descriptive study among 225 subjects (ages of 18–35 years) from whom BP, body weight, and height were collected. Visual acuity was measured using the Snellen chart following standard procedures of number of letters seen at 6-metre distance. The data were then analyzed using SPSS version 17. Results. The sampled population consists of 112 male and 113 female (mean age 31.72±14.2 years). Majority (180) of the respondents had normal visual acuity. However, compared with the respondents with normal BMI (R19.61±1.5; L19.67±1.70), visual acuity of underweight (R18.53±2.30; L18.53±2.70) and obese (R15.68±4.79; L17.73±1.70) were more deviated. Similarly, compared with respondent with normal BP (120–125/80–85 mmHg; R18.00±2.53; L18.07±3.11), hypotensive (R15.5±7.35; L15.00±10.20), and hypertensive (R15.01±21.25; L15.00±11.91) respondents had deviated visual acuity. Conclusion. Abnormal body weight (underweight and obese) and BP (hypotension and hypertension) have potential negative impacts on visual acuity. Based on the observed relationship between weights, BP, and visual acuity, eye examinations can be included as regular screening exercise for abnormal BMI and BP conditions.


Author(s):  
Maria do Socorro Simoes ◽  
Fernando Wehrmeister ◽  
Marcello Romiti ◽  
Antonio de Toledo Gagliardi ◽  
Rodolfo Arantes ◽  
...  

We investigated if cardiorespiratory fitness modifies the association between obesity and the level of physical activity. In this cross-sectional study, we analyzed data from 746 adults, free of diagnosed cardiorespiratory or locomotor diseases. We analyzed sociodemographic and clinical information, cardiovascular risk factors, cardiorespiratory fitness, anthropometry, and level of physical activity (time spent in moderate-to-vigorous physical activity). Those that spent more time in moderate-to-vigorous physical activity were younger, male, with lower body mass index, without self-reported arterial blood hypertension, diabetes and dyslipidemia, non-smokers, and presented with better cardiorespiratory fitness. The linear regression coefficients showed that cardiorespiratory fitness changes according to the level of physical activity and body mass index (obesity in low cardiorespiratory fitness: β 6.0, p = 0.213, 95%CI -3.5 to 15.6; in intermediate cardiorespiratory fitness: β 6.3, p = 0.114, 95%CI -1.5 to 14.2; in high cardiorespiratory fitness: β -6.3, p = 0.304, 95%CI -18.4 to 5.8). This effect modification trend was present after adjusting the model by covariates. Cardiorespiratory fitness potentially modifies the association between body mass index and the level of physical activity. It should be routinely assessed to identify persons with overweight/ obesity with low/ intermediate cardiorespiratory fitness to prescribe individualized training.


Nutrients ◽  
2017 ◽  
Vol 9 (7) ◽  
pp. 644 ◽  
Author(s):  
Robinson Ramírez-Vélez ◽  
Antonio García-Hermoso ◽  
Cesar Agostinis-Sobrinho ◽  
Jorge Mota ◽  
Rute Santos ◽  
...  

2017 ◽  
Vol 27 (1) ◽  
pp. 56 ◽  
Author(s):  
Willian R. Tebar ◽  
Luiz Carlos M. Vanderlei ◽  
Catarina C. Scarabotollo ◽  
Edner F. Zanuto ◽  
Bruna T. C. Saraiva ◽  
...  

Objectives: The aim of this study was to determine the prevalence of abdominal obesity and its associated factors among adolescents, independent of confounders. Method: A sample of 14–17-year-old individuals (n=1.231), who were students from Londrina/PR-Brazil public schools, was studied. A questionnaire about physical activity, sedentary behaviour and socioeconomic conditions was applied. Anthropometry was composed of body weight (kg), height (m), body mass index (BMI=kg/m²) and waist circumference (cm). The association of abdominal obesity and independent variables was assessed using the chi-square test and the magnitude of associations was verified using Binary Logistic Regression in an unadjusted model and adjusted for confounders (gender, age, socioeconomic status, physical activity and sedentary behaviour). The confidence interval and statistical significance were set at 95% and 5%, respectively, using SPSS v15.0. Results: The abdominal obesity prevalence was 17.5% (CI = 15.4%–19.6%), and was higher in boys than in girls. Adolescents with abdominal obesity had higher values of body weight, height, body mass index and sedentary behaviour compared to eutrophic individuals. Being male increased the risk of abdominal obesity by 36% in adolescents. This risk was two times higher in those with high levels of sedentary behaviour. Conclusion: Abdominal obesity was significantly associated with gender and high levels of sedentary behaviour, regardless of confounding factors. Lifestyle habits are important modifiable risk factors that can effectively contribute to the reduction of obesity from an early age.


MEDIKORA ◽  
2015 ◽  
Vol 11 (2) ◽  
Author(s):  
Prijo Sudibjo ◽  
Novita Intan Arovah ◽  
Rachmah Laksmi Ambardini

Mahasiswa Program Studi Pendidikan Kepelatihan Olahraga Fakultas Ilmu Keolahragaan dipersiapkan menjadi pelatih yang kompeten. Salah satu kompetensi yang diperlukan oleh pelatih adalah pemahaman dan keterampilan dalam pengukuran tingkat aktivitas fisik, status kecukupan energi dan status antropometrik. Tujuan penelitian ini adalah untuk mengetahui dan memahami pengukuran level aktivitas fisik, status kecukupan energy, dan status antropometrik mahasiswa Program Studi Pendidikan Kepelatihan Olahraga FIK UNY. Penelitian ini merupakan penelitian observasi cross sectional pada 30 mahasiswa Program Stusi Pendidikan Kepelatihan Olahraga FIK UNY yang telah menempuh mata kuliah Anatomi. Pengukuran tingkat pemahaman dilaksanakan dengan metode tes. Level aktivitas fisik diukur dengan kuesioner IPAQ (International Physical Activity Questionnaire), status kecukupan energi diukur dengan membagi antara asupan kalori dibagi dengan kebutuhan kalori, dan status antropometris dinilai dengan menggunakan rumus BMI (body mass index) dansomatotype berdasarkan Health Charter Manual. Data diolah secara deskriptif dan korelatif menggunakan analisis Korelasi Pearson untuk melihat hubungan antara tingkat pemahaman dan status level aktivitas fisik, status kecukupan energy, dan status antropometrik dengan program SPSS. Hasil penelitian menunjukkan bahwa pada semua mahasiswa Program Studi Pendidikan Kepelatihan Olahraga FIK UNY mempunyai level aktivitas fisik yang baik (skor IPAQ rata-rata 7248,13 ± 2420,58 METS), dan status kecukupan energi yang baik pula (rata-rata kecukupan energi sebesar 96,62 ± 19,81%). Di sisi lain, status gizi pada 90 % mahasiswa menunjukkan kriteria yang normal. Uji Korelasi Pearson menunjukkan adanya korelasi positif yang sangat kuat antara tingkat pemahaman level aktivitas fisik dan level aktivitas fisik (korelasi 0.902 dan p < 0,05), namun tidak terbukti adanya korelasi yang signifikan (p > 0,05) antara tingkat pemahaman dan status kecukupan energi dan status gizi yang secara berurutan didapatkan nilai korelasi sebesar 0,27 dan 0,048.Kata Kunci: level aktivitas fisik, status kecukupan energi, status antropometrik


Author(s):  
Futoon S. Alobiri ◽  
Roaa A. Alharbi ◽  
Mohammed R. Algethami ◽  
Raghdah H. Ateeq ◽  
Aseel M. Badurayq ◽  
...  

Aim: Identify the relation between poor esteem for body image and weight-related behaviors. The results will help increase awareness and improve students’ lifestyles to have a better body image and achieve ideal body weight. Methods: A cross-sectional study was conducted among King Abdulaziz University medical students (n= 460) between July to the end of August 2019. Data was collected using the International physical activity questionnaire (IPAQ), figure rating scale (FRS) and analyzed using SPSS software. Result: The results showed that the average Body Mass Index (BMI) was 24.80 ± 11.89. Participant sex was an important factor influencing the prevalence of obesity; male students were more obese than female students with a significant difference (p<0.001). The level of body satisfaction was also affected by gender. Students in preclinical years were more likely to gain weight more than clinical years students. Conclusion: The results show a significant relationship between body satisfaction and gender (P<0.0001) despite having diverse BMIs. Overweight and obese males and females' participants had the lowest body satisfaction. Females who were too thin and had low BMIs described themselves as normal, while males describe themselves as too thin. Conversely, females with high BMIs described themselves as too fat, while males described themselves as normal. This could be due to different factors. Also, underweight females and males have high body satisfaction, which can lead to dangerous behaviors to maintain low body weight which cause negative health consequences.


2020 ◽  
Vol 8 (E) ◽  
pp. 308-312
Author(s):  
Siham Lghoul ◽  
Mohamed Loukid ◽  
Mohamed Kamal Hilali

BACKGROUND: Adolescence is associated with many physical changes, it is described as a period when body weight changes and is likely to become worrying for many adolescents. AIM: This study aims to evaluate associations between body weight perception and body mass index (BMI) among a population of female adolescents. METHODS: A cross-sectional school-based study was conducted from February to May 2017 among 12–19 years olds adolescents (n = 415) from high and middle school. BMI for age percentiles was calculated using the WHO AnthroPlus. Body weight perception was determined using an anonymous questionnaire. RESULTS: The prevalence of misconception of body weight was 60%. The prevalence of misconception was positively associated with the participants age (p < 0.001), the occurrence of menarche (p < 0.05), the increasing of BMI (p < 0.001), and with habits diet satisfaction (p < 0.05). Overweighed participants and who’s with normal weight were more likely to perceive their weight incorrectly (p < 0.05). Furthermore, approximately 2.9% of participants underestimated their true body weight and 57.1% overestimated their weight. However, all participants with underweight had correctly perceived their body weight. Logistic regression showed that predictor factors of misconception weight were participant’s age and BMI. CONCLUSION: It is recommended to improve healthy programs in schools aimed at preventing body weight perception and eating problems among adolescents.


2011 ◽  
Vol 21 (6) ◽  
pp. 603-607 ◽  
Author(s):  
Trenda D. Ray ◽  
Angela Green ◽  
Karen Henry

AbstractBackgroundChildren with congenital cardiac disease experience challenges in developing healthy patterns of physical activity due to decreased exercise capacity and parental fear and confusion about what is permissible. The purpose of this study was to describe physical activity habits in children 10–14 years of age with congenital cardiac disease and the relationship of those habits to obesity as defined by body mass index.MethodsThis cross-sectional study used self-report measures and clinical data to describe the association between physical activity participation and body mass index in 10- to 14-year-old children with congenital cardiac disease. Further, physical activity levels were compared between children who were overweight or obese and those who were not.ResultsChildren (n = 84; 51 males; 33 females) reported low rates of physical activity compared to reports on healthy children. Only 9.5% were overweight (body mass index between the 85th and 94th percentile), and alarmingly 26% were obese (body mass index at or above the 95th percentile). Physical activity and body mass index were not significantly correlated (r = −0.11, p = 0.45) and there was no significant difference in mean physical activity (t = 0.67) between children who were overweight or obese and those who were not.ConclusionsChildren in this study reported low rates of physical activity and a higher obesity rate than was reported in previous studies. However, the two were not significantly correlated. Further research is indicated to determine the specific factors contributing to obesity and to test interventions to combat obesity in children with congenital cardiac disease.


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