scholarly journals A retrospective serologic survey of hantavirus infections in the county of Cássia dos Coqueiros, State of São Paulo, Brazil

2012 ◽  
Vol 45 (4) ◽  
pp. 468-470 ◽  
Author(s):  
Soraya Jabur Badra ◽  
Felipe Gonçalves Mota Maia ◽  
Glauciane Garcia Figueiredo ◽  
Gilberto Sabino dos Santos Junior ◽  
Gelse Mazzoni Campos ◽  
...  

INTRODUCTION: In recent years, hantavirus infections producing severe diseases have obtained an increased attention from public health authorities from the countries of Eurasia to the Americas. Brazil has reported 1,300 cases of hantavirus cardiopulmonary syndrome (HCPS) from 1993 to 2010, with about 80 of them occurring in the northeast of the State of São Paulo, with 48% fatality rate. Araraquara virus was the causative agent of HCPS in the region. Considering that hantaviruses causing human disease in the Americas were unknown until 1993, we have looked for hantavirus infections in the population of Cássia dos Coqueiros county, northeast of the State of São Paulo, Brazil, before this time. This county has about 2,800 inhabitants and an economy based on agriculture, including cultivation of Brachiaria decumbens grass. The grass seeds are an important rodent attraction, facilitating transmission of hantavirus to man. Four HCPS cases were reported so far in the county. METHODS: In this study, 1,876 sera collected from 1987 to 1990 were tested for IgG to hantavirus by IgG-ELISA, using the N recombinant protein of Araraquara virus as antigen. RESULTS: Positive results were observed in 89 (4.7%) samples, which were all collected in 1987. The positivity among urban inhabitants was 5.3%, compared with 4.3% among those living in rural areas. CONCLUSIONS: Our results showed that hantavirus infections occurred in Cássia dos Coqueiros, completely unrecognized, even before hantaviruses were described in the Americas.

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Marcos Amaku ◽  
Dimas Tadeu Covas ◽  
Francisco Antonio Bezerra Coutinho ◽  
Raymundo Soares Azevedo ◽  
Eduardo Massad

Abstract Background At the moment we have more than 177 million cases and 3.8 million deaths (as of June 2021) around the world and vaccination represents the only hope to control the pandemic. Imperfections in planning vaccine acquisition and difficulties in implementing distribution among the population, however, have hampered the control of the virus so far. Methods We propose a new mathematical model to estimate the impact of vaccination delay against the 2019 coronavirus disease (COVID-19) on the number of cases and deaths due to the disease in Brazil. We apply the model to Brazil as a whole and to the State of Sao Paulo, the most affected by COVID-19 in Brazil. We simulated the model for the populations of the State of Sao Paulo and Brazil as a whole, varying the scenarios related to vaccine efficacy and compliance from the populations. Results The model projects that, in the absence of vaccination, almost 170 thousand deaths and more than 350 thousand deaths will occur by the end of 2021 for Sao Paulo and Brazil, respectively. If in contrast, Sao Paulo and Brazil had enough vaccine supply and so started a vaccination campaign in January with the maximum vaccination rate, compliance and efficacy, they could have averted more than 112 thousand deaths and 127 thousand deaths, respectively. In addition, for each month of delay the number of deaths increases monotonically in a logarithmic fashion, for both the State of Sao Paulo and Brazil as a whole. Conclusions Our model shows that the current delay in the vaccination schedules that is observed in many countries has serious consequences in terms of mortality by the disease and should serve as an alert to health authorities to speed the process up such that the highest number of people to be immunized is reached in the shortest period of time.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Demian da Silveira Barcellos ◽  
Giovane Matheus Kayser Fernandes ◽  
Fábio Teodoro de Souza

AbstractThere is an ongoing need for scientific analysis to help governments and public health authorities make decisions regarding the COVID-19 pandemic. This article presents a methodology based on data mining that can offer support for coping with epidemic diseases. The methodological approach was applied in São Paulo, Rio de Janeiro and Manaus, the cities in Brazil with the most COVID-19 deaths until the first half of 2021. We aimed to predict the evolution of COVID-19 in metropolises and identify air quality and meteorological variables correlated with confirmed cases and deaths. The statistical analyses indicated the most important explanatory environmental variables, while the cluster analyses showed the potential best input variables for the forecasting models. The forecast models were built by two different algorithms and their results have been compared. The relationship between epidemiological and environmental variables was particular to each of the three cities studied. Low solar radiation periods predicted in Manaus can guide managers to likely increase deaths due to COVID-19. In São Paulo, an increase in the mortality rate can be indicated by drought periods. The developed models can predict new cases and deaths by COVID-19 in studied cities. Furthermore, the methodological approach can be applied in other cities and for other epidemic diseases.


2021 ◽  
Vol 24 ◽  
Author(s):  
Rodrigo Constante Martins ◽  
Alexsandro Elias Arbarotti ◽  
Raiza Campregher

Abstract The water resources management model in the state of São Paulo is characterized by the participation of water users from different sectors of the economy within the ambit of River Basin Committees and other organizations of the water management system. The purpose of this article is to present a survey and systematization of the performance of representatives of São Paulo’s agricultural sector in this decentralized and participatory system of water governance. To this end, this article recreates the profile of this sectoral representation in the State Water Resources Council and in the Committees for rural areas with strong agricultural dynamics in the state. The findings of this study reveal significant political and propositional differences between São Paulo’s agriculture and agroindustry sectors. Such differences have to do with the structure and capillarity of the entities that represent these sectors, as well as their divergent concept of management.


1993 ◽  
Vol 9 (4) ◽  
pp. 466-476 ◽  
Author(s):  
Dalva Marli V. Wanderley

In the first half of this century - a period of expanding coffee cultivation - there was a close relationship between the growth of cleared spaces, the domestication of triatomines, and the establishment of Chagas' disease in the state of São Paulo. However, the initiation of control mesuares in 1950 coincided with a period characterized by a progressive reversal of the conditions that had facilitated the establishment of Chagas' disease in the first place. Alterations were taking place in the agricultural environment, rural areas were becoming depopulated, and low-grade housing was being destroyed. Natural transmission of the endemic was interrupted in the mid-1970's, following the elimination of Triatoma infestans from homes. Subsequently, however, a challenge emerged from two extradomiciliary species, Triatoma sordida and Panstrongylus megistus. The invasive character of these species made it necessary to investigate their possible repercussions on human populations and to set up permanent programs of epidemiological surveillance involving direct participation by local populations.


2012 ◽  
Vol 54 (6) ◽  
pp. 311-314 ◽  
Author(s):  
Dalva Assunção Portari Mancini ◽  
Rita Maria Zucatelli Mendonça ◽  
Aparecida Santo Pietro Pereira ◽  
Adélia Hiroko Nagamori Kawamoto ◽  
Camila Infantosi Vannucchi ◽  
...  

In 1970, searching for the interspecies transmission of influenza viruses led to the first study on influenza viruses in domestic animals. Birds and mammals, including human beings, are their natural hosts; however, other animals may also play a role in the virus epidemiology. The objective was to investigate the incidence of influenza viruses in adult dogs raised in rural (9, 19.56%) and urban (37, 80.43%) areas in the state of São Paulo, Brazil. Dog serum samples were examined for antibodies to influenza viruses by the hemagglutination inhibition (HI) test using the corresponding antigens from the circulating viruses in Brazil. Dogs from rural areas presented antibodies to influenza A H3N2, and influenza A H7N7 and H3N8. In rural areas, dog sera displayed mean titers as 94.37, 227.88, 168.14, 189.62 HIU/25 µL for subtypes H1N1, H3N2, H7N7, H3N8, respectively. About 84% and 92% of dogs from urban areas exhibited antibodies to human influenza A H1N1 and H3N2, respectively, with statistical difference at p < 0.05 between the mean titers of antibodies to H1N1 and H3N2. About 92% and 100% were positive for H7N7 and H3N8, respectively. In dogs from urban areas, the mean titers of antibodies against influenza A H1N1, H3N2, H7N7 and H3N8, were 213.96, 179.42, 231.76, 231.35 HIU/25 µL respectively. The difference among them was not statistically significant at p > 0.05. In conclusion, these dogs were positive for both human and equine influenza viruses. The present study suggests the first evidence that influenza viruses circulate among dogs in Brazil.


2021 ◽  
Author(s):  
Eduardo Massad ◽  
Marcos Amaku ◽  
Dimas Tadeu Covas ◽  
Francisco Antonio Bezerra Coutinho ◽  
Raymundo Soares Azevedo

Abstract BackgroundAt the moment we have more than 109 million cases and 2.4 million deaths around the world and vaccination represents the only hope to control the pandemic. Imperfections in planning vaccine acquisition and difficulties in implementing distribution among the population, however, have hampered the control of the virus so far.MethodsWe propose a new mathematical model to estimate the impact of vaccination delay against the 2019 coronavirus induces disease (COVID-19) on the number of cases and deaths by the disease in Brazil. We apply the model to Brazil as a whole and to the State of Sao Paulo, the most affected by COVID-19 in Brazil. We simulated the model for the populations of the State of Sao Paulo and Brazil as a whole, varying the scenarios related to vaccine efficacy and compliance from the populations.ResultsThe model projects that, in the absence of vaccination, almost 170 thousand deaths and more than 350 thousand deaths until the end of 2021 for Sao Paulo and Brazil, respectively. If in contrast, Sao Paulo and Brazil had enough vaccine supply and so started a vaccination campaign in January with the maximum vaccination rate, compliance and efficacy, they could have averted more than 112 thousand deaths and 127 thousand deaths, respectively. In addition, that for each month of delay the number of deaths increases monotonically in a logarithm fashion, for both the State of Sao Paulo and Brazil as a whole.ConclusionsOur model shows that the current delay in the vaccination schedules that is observed in many countries has serious consequences in terms of mortality by the disease and should serve as an alert to health authorities to speed the process up such that the highest number of people to be immunized is reached in the shortest period of time.


1997 ◽  
Vol 39 (5) ◽  
pp. 257-260 ◽  
Author(s):  
Sérgio Di Camilo FAVA ◽  
Evandro A. RIVITTI ◽  
Luiz Carlos CUCÉ ◽  
Simone WEISS ◽  
Gianine RIGONE ◽  
...  

This work was planned by taking into account all the knowledge accumulated from the immunological study of paracoccidioidomycosis. It aimed at comparing a polysaccharide antigen from Histoplasma capsulatum to a classic histoplasmin with the help of intradermal tests of delayed type of hypersensitivity. Tests were applied to 115 individuals in Santo Amaro, a town in the state of São Paulo. Positive results using classic histoplasmin were obtained in 46.0% cases whereas positive results using the polysaccharide antigen at its hightest concentration were obtained in 51.30% cases. The major conclusion in this investigation is that it is possible to use the polysaccharide antigen as histoplasmin instead of the filtrate antigen


2021 ◽  
Vol 37 (9) ◽  
Author(s):  
Bruno Kabke Bainy ◽  
Ilma Aparecida Paschoal ◽  
Ana Maria Heuminski de Avila ◽  
Henrique Oliveira dos Santos

On March 24, 2020, a partial lockdown was decreed in the state of São Paulo, Brazil, as a measure to hinder the spread of COVID-19, which consisted in prohibiting crowding and advising people to stay home, except for urgent or extremely necessary matters. Based on studies performed in other countries, this study aims to assess the impacts of the lockdown on the air quality of five cities in the state of São Paulo. Our study was conducted by using particulate matter and nitrogen dioxide as air quality indicators, and by correlating the contaminants concentrations with weather data. The results showed an increase in these contaminants in all cities within the first weeks after the lockdown compared with the weeks before the decree and with the same period in previous years. This result is inconsistent with the literature. Therefore, a secondary goal was set to investigate the possible cause (or causes) of such deterioration in air quality, which led to the increased number of wildfires. The anomalous dry weather favored the burning of vegetation in agricultural rural areas and in small, vegetated areas near the municipalities, and limited pollution scavenging by rainfall, both of which contributed to higher pollution concentration. We hypothesize the possible effects of worse air quality on the aggravation of COVID-19, but further research is necessary to obtain a complete assessment.


2021 ◽  
Vol 6 (3) ◽  
pp. 156
Author(s):  
Sérgio Munhoz Pereira ◽  
Charlene Troiani do Nascimento ◽  
Rodrigo Sala Ferro ◽  
Edilson Ferreira Flores ◽  
Elaine Aparecida Maldonado Bertacco ◽  
...  

Co-epidemics of COVID-19 and dengue in dengue-endemic countries represent a serious public health concern. In Brazil, São Paulo state ranks first for cases and deaths from COVID-19, and dengue is endemic in most regions of the country. In 2020, an outbreak of dengue occurred in western São Paulo. We determined the spatiotemporal distribution of dengue in the context of COVID-19 cases in Presidente Prudente, a mid-sized city in western São Paulo. To illustrate the burden of both infections, a case report of a doctor and his family, infected with dengue and COVID-19, is presented. There were three clusters of dengue and COVID-19 in the periphery. A dengue cluster was found in a region where there were no corresponding COVID-19 cases. Meanwhile, there were COVID-19 clusters where dengue activity was lower. In 2020, the COVID-19 epidemic emerged when dengue reached its seasonal peak, resulting in a simultaneous outbreak of both diseases. Lower rates of dengue were found in the city compared with 2019, and the fear of patients with mild dengue symptoms about remaining in hospital and acquiring COVID-19 infection may be the main cause. Simultaneous spatial clusters of dengue and COVID-19 in environmentally and socioeconomically vulnerable areas can guide public health authorities in intensive interventions to improve clinical diagnosis, epidemiological surveillance, and management of both diseases. The patient and his family were first infected with dengue and he then carried COVID-19 to his family, reinforcing the risk of health care workers spreading the virus to the community. We highlight the epidemiological significance of presenting a case report and spatial analysis of COVID-19 in the same study in the context of a dengue outbreak.


2012 ◽  
Vol 38 (1) ◽  
Author(s):  
Nelly Maria Sansigolo de Figueiredo ◽  
Bruna Angela Branchi ◽  
Angela Antonia Kageyama

O rural da Região Metropolitana de São Paulo (RMSP) pode ser considerado um caso extremo de rural, altamente integrado com o espaço urbano. O principal objetivo deste trabalho é investigar as condições das famílias rurais na RMSP e contrastar os resultados com as famílias rurais residentes em áreas não-metropolitanas do estado de São Paulo em 2008, focalizando em aspectos relacionados à ocupação, renda, pobreza. Complementarmente, os resultados para2008 são contrastados com os de 2004. A base de dados é fornecida pela Pesquisa Nacional por Amostra de Domicílios (PNAD) de 2004 e de 2008. As famílias rurais foram classificadas em agrícolas, não-agrícolas e pluriativas e segundo dois cortes geográficos (RMSP e demais áreas rurais do estado de São Paulo). Os resultados indicam que o rural metropolitano é eminentemente não-agrícola, constituído porfamílias ocupadas em atividades não-agrícolas, caracterizadas pela maior presença de jovens, maior escolaridade, empregos formais e acesso a itens como água encanada. No entanto, essas famílias estão em piores condições quanto à renda e pobreza comparativamente às famílias rurais não metropolitanas. A proporção pequena de ocupados na agricultura sugere que a proximidade com a metrópole, apesar de oferecer algumas vantagens para as famílias rurais não representa uma integração rural-urbana, uma vez que a ruralidade da família em torno da ocupação agrícola e da agricultura familiar está muito distante desse grupo.Rural workers and families in the Metropolitan area of São Paulo: earnings diversification and families´characteristics in 2008Abstract: The rural area of the Metropolitan Region of Sao Paulo city (RMSP) may be considered a singular situation of rural area, highly integrated to the urban center. In this context, the main purpose of this article is to investigatethe socioeconomic conditions of the rural families. Aiming to this objective a comparison was undertaken between rural families living in the metropolitan area (RMSP) and those living in other rural areas of the state, with special attentionto occupation, income and poverty. Data base comes from the 2004 and 2008 National Household Sample Survey (PNAD) from IBGE (Brazilian Geography and Statistics Institute), considering two samples of the rural families: type of family(agricultural, non-agricultural and pluriactive); and region (the metropolitan rural area RMSP and the other rural areas of the state of São Paulo). The results suggest that most families in the metropolitan rural area have their membersoccupied in non-agricultural activities. In general, these families are characterized by a stronger presence of youngsters, higher educational level, greater proportionof formal jobs and access to basic public services as piped water. Nevertheless, with respect to income and poverty, these families present worse conditions, when compared to the non-metropolitan rural families. The small proportion of workers engaged in agricultural activities suggests that the proximity with the metropolis does not contribute to a rural-urban integration, given that the rurality of the family, expressed by the agricultural occupation and the family farming, is not a peculiarity of this group.Key-words: rural families; Metropolitan area of Sao Paulo city.JEL: J08; J29.


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