scholarly journals Mortality from idiopathic pulmonary fibrosis: a temporal trend analysis in Brazil, 1979-2014

2017 ◽  
Vol 43 (6) ◽  
pp. 445-450 ◽  
Author(s):  
Eduardo Algranti ◽  
Cézar Akiyoshi Saito ◽  
Diego Rodrigues Mendonça e Silva ◽  
Ana Paula Scalia Carneiro ◽  
Marco Antonio Bussacos
Keyword(s):  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Temporal Trend ◽  
Population Aging ◽  
Age Groups ◽  
International Classification Of Diseases ◽  
Mortality Rates ◽  
Age Group ◽  
Classification Of Diseases ◽  
And Gender

ABSTRACT Objective: To analyze mortality from idiopathic pulmonary fibrosis (IPF) in Brazil over the period 1979-2014. Methods: Microdata were extracted from the Brazilian National Ministry of Health Mortality Database. Only deaths for which the underlying cause was coded as International Classification of Diseases version 9 (ICD-9) 515 or 516.3 (until 1995) or as ICD version 10 (ICD-10) J84.1 (from 1996 onward) were included in our analysis. Standardized mortality rates were calculated for the 2010 Brazilian population. The annual trend in mortality rates was analyzed by joinpoint regression. We calculated risk ratios (RRs) by age group, time period of death, and gender, using a person-years denominator. Results: A total of 32,092 deaths were recorded in the study period. Standardized mortality rates trended upward, rising from 0.24/100,000 population in 1979 to 1.10/100,000 population in 2014. The annual upward trend in mortality rates had two inflection points, in 1992 and 2008, separating three distinct time segments with an annual growth of 2.2%, 6.8%, and 2.4%, respectively. The comparison of RRs for the age groups, using the 50- to 54-year age group as a reference, and for the study period, using 1979-1984 as a reference, were 16.14 (14.44-16.36) and 6.71 (6.34-7.12), respectively. Men compared with women had higher standardized mortality rates (per 100,000 person-years) in all age groups. Conclusion: Brazilian IPF mortality rates are lower than those of other countries, suggesting underdiagnosis or underreporting. The temporal trend is similar to those reported in the literature and is not explained solely by population aging.

scholarly journals Mortality Associated with Idiopathic Pulmonary Fibrosis in Northeastern Italy, 2008–2020: A Multiple Cause of Death Analysis

2021 ◽  
Vol 18 (14) ◽  
pp. 7249
Author(s):  
Alessandro Marcon ◽  
Elena Schievano ◽  
Ugo Fedeli
Keyword(s):  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Cause Of Death ◽  
Age Groups ◽  
Mortality Rates ◽  
Annual Percent Change ◽  
Northeastern Italy ◽  
Mortality Ratio ◽  
The Impact ◽  
Related Mortality

Mortality from idiopathic pulmonary fibrosis (IPF) is increasing in most European countries, but there are no data for Italy. We analysed the registry data from a region in northeastern Italy to assess the trends in IPF-related mortality during 2008–2019, to compare results of underlying vs. multiple cause of death analyses, and to describe the impact of the COVID-19 epidemic in 2020. We identified IPF (ICD-10 code J84.1) among the causes of death registered in 557,932 certificates in the Veneto region. We assessed time trends in annual age-standardized mortality rates by gender and age (40–74, 75–84, and ≥85 years). IPF was the underlying cause of 1310 deaths in the 2251 certificates mentioning IPF. For all age groups combined, the age-standardized mortality rate from IPF identified as the underlying cause of death was close to the European median (males and females: 3.1 and 1.3 per 100,000/year, respectively). During 2008–2019, mortality rates increased in men aged ≥85 years (annual percent change of 6.5%, 95% CI: 2.0, 11.2%), but not among women or for the younger age groups. A 72% excess of IPF-related deaths was registered in March–April 2020 (mortality ratio 1.72, 95% CI: 1.29, 2.24). IPF mortality was increasing among older men in northeastern Italy. The burden of IPF was heavier than assessed by routine statistics, since less than two out of three IPF-related deaths were directly attributed to this condition. COVID-19 was accompanied by a remarkable increase in IPF-related mortality.

scholarly journals Trends in mortality from idiopathic pulmonary fibrosis in the European Union: an observational study of the WHO mortality database from 2001–2013

2018 ◽  
Vol 51 (1) ◽  
pp. 1701603 ◽  
Author(s):  
Dominic C. Marshall ◽  
Justin D. Salciccioli ◽  
Barry S. Shea ◽  
Praveen Akuthota
Keyword(s):  
European Union ◽  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Scar Tissue ◽  
International Classification Of Diseases ◽  
Mortality Rates ◽  
World Health ◽  
The European Union ◽  
Mortality Trends ◽  
Country Level

Idiopathic pulmonary fibrosis (IPF) is the most common of the idiopathic interstitial pneumonias and is characterised by progressive accumulation of scar tissue in the lungs. The objective of this study was to describe the current mortality rates due to IPF in Europe, based on the World Health Organization (WHO) mortality database.We used country-level data for IPF mortality, identified in the WHO mortality database using International Classification of Diseases 10th Edition (ICD-10) codes, for the period 2001–2013. Joinpoint analysis was performed to describe trends throughout the observation period.The median mortality was 3.75 per 100 000 (interquartile range (IQR) 1.37–5.30) and 1.50 per 100 000 (IQR 0.65–2.02) for males and females, respectively. IPF mortality increased in the majority of the European Union (EU) countries with the exceptions of Denmark, Croatia, Austria and Romania. There was a significant disparity in rates across Europe, in the range 0.41–12.1 per 100 000 for men and 0.24–5.63 per 100 000 for women. The most notable increases were observed in the United Kingdom and Finland. Rates were also substantially higher in males, with sex disparity increasing across the period.The reported IPF mortality appears to be increasing across the EU; however, there is substantial variation in mortality trends and overall reported mortality rates between countries.

Accelerated melanoma mortality rates among middle-aged white males with tumors of all thicknesses.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. e21029-e21029
Author(s):  
Juliana Berk-Krauss ◽  
David Polsky ◽  
Jennifer Stein ◽  
Alan Geller
Keyword(s):  
White Women ◽  
Age Groups ◽  
White Men ◽  
Mortality Rates ◽  
Age Group ◽  
Middle Aged ◽  
Mortality Trends ◽  
Men And Women ◽  
And Gender ◽  
Melanoma Mortality

e21029 Background: Effective early detection of melanoma remains one of the most crucial strategies in improving patient prognosis, due to the inverse relationship between primary tumor thickness and survival time. However, recent studies have demonstrated the mortality burden of thin melanomas is at least as severe as that of thicker melanomas. Recognizing specific mortality trends among men and women by age and thickness is essential for establishing targeted melanoma screening efforts. Methods: We evaluated Surveillance, Epidemiology and End Results (SEER) data from 2009-2013. Melanoma thickness was divided into four standard categories: 0.01-1.00mm, 1.01-2.00mm, 2.01-4.00mm and > 4.01 mm. Melanoma mortalities were calculated among white men and women by age and thickness. We used a Bayesian analysis to calculate the probability of an individual dying from a melanoma of a given gender, age, and thickness. We then compared these probabilities between men and women. Results: Among white men, the largest increases in mortality rates occurred in the jump from the 45-49 to 50-54 age group at an increase of 68% for 0.01-1.00mm tumors, and from the 50-54 to 55-59 age group at an increase of 91% for 1.01-2.00mm tumors, 71% 2.01-4.00mm tumors and 80% for > 4.01mm tumors. In white women, mortality rates regardless of thickness increased at a slow incremental pace, across all age groups at an average overall rate of 36%. Mortality rates for white men with < 1mm and 1.01-2mm melanomas were comparable within the age groups less than 64 years, as was the case for white women with tumors of these thicknesses. The probability of a man dying was greater than of a woman for any age or thickness category. Conclusions: Melanoma mortality rate trends are nuanced and can vary significantly by age, thickness, and gender. In white men, mortality rates begin to accelerate sharply around the mid-50s age group. Screening efforts should therefore target detecting melanoma in middle-aged males in the in situ or earliest stage.

scholarly journals Polymorbidity in hypertensive patients

2019 ◽  
Vol 25 (2) ◽  
pp. 200-208
Author(s):  
E. V. Sevostyanova ◽  
Yu. A. Nikolaev ◽  
I. M. Mitrofanov ◽  
V. Ya. Polyakov
Keyword(s):  
Circulatory System ◽  
Endocrine System ◽  
West Siberia ◽  
International Classification Of Diseases ◽  
High Rate ◽  
Age Group ◽  
Hypertensive Patients ◽  
Classification Of Diseases ◽  
Icd 10 ◽  
And Gender

Background. Hypertension (HTN) is often combined with other diseases, that significantly complicate its course, worsen the prognosis, interfere with the therapeutic and preventive measures. Therefore, assessing the development and structure of polymorbidity (PM) in hypertension is a relevant issue. Objective. To study the structure and degree of PM in hypertensive patients depending on age and gender. Design and methods. We conducted an analysis of 20 560 case histories of patients with HTN and without HTN (men and women), inhabitants of West Siberia-Novosibirsk region, who underwent examination and treatment at the clinic of the Federal Research Center of Fundamental and Translational Medicine in Novosibirsk. All identified diagnoses (nosological forms and classes according to the International Classification of Diseases of the 10th revision, ICD‑10) were considered. Transnosological PM was assessed by the average number of nosologies corresponding to the three-digit ICD‑10 rubric. Results. An increase in the PM index by 16,8 % was found in HTN patients compared to patients without HTN. Among HTN patients, there was an increase in the incidence of comorbid diseases of the circulatory system (in the 16–39 age group in men — by 46 %, in women — by 42,8 %), the endocrine system, eating disorders and metabolism (in the age group 16–39 years for men — by 19,3 %, for women — by 45,2 %), the musculoskeletal system, urinary system (for men) and neoplasms (for women) compared with patients without HTN. Conclusions. We found a high rate of transnosological PM in HTN patients was found and defined its structure.

scholarly journals Analysis of age–sex and deprivation stratified trends in assault deaths in Scotland (1974–2015) to identify age, period or cohort effects

BMJ Open ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. e030064
Author(s):  
Jane Parkinson ◽  
Jon Minton ◽  
Gerry McCartney
Keyword(s):  
Age Groups ◽  
Young Men ◽  
International Classification Of Diseases ◽  
Mortality Rates ◽  
Cohort Effects ◽  
Area Deprivation ◽  
Period Effect ◽  
Men And Women ◽  
Classification Of Diseases ◽  
Deprived Areas

ObjectivesMortality rates in Scotland are higher, and health inequalities are greater, than in the rest of Western and Central Europe. There was a marked divergence during the 1980s and 1990s in the Scottish rates partly due to rises in alcohol-related and drug-related deaths, suicide and deaths by assault. This study examines whether age, period or cohort effects account for the trends in death by assault in Scotland and any sex or deprivation inequalities in these.DesignWe calculated crude and age-standardised mortality rates for deaths by assault for Scottish men and women from 1974 to 2015 for the population overall and for populations stratified by Carstairs area of deprivation. We examined age–sex stratified trends to identify obvious age–period–cohort effects.SettingThis study was conducted in Scotland.ParticipantsMen and women whose registered death by the International Classification of Diseases was due to assault from 1974 to 2015 (n=3936) were included in this study.ResultsWhereas age-standardised mortality rates from this cause fell gradually for women since 1974, for men they increased in the early 1990s and remained higher until around 2006, before falling. Death by assault was substantially more common among men aged around 15–50 years and in the most deprived areas. There was little change in the age groups most impacted over time, which made cohort effects unlikely. A period effect for the 15 years until 2006, with a consistent age–sex–area deprivation patterning, was evident.ConclusionsMortality due to assault in Scotland is unequally felt, with young men living in the most deprived areas suffering the highest rates. There is a 15-year period effect up until 2006, impacting on young men as an age–period interaction, with no obvious cohort effects. Exploration of the demographics of criminological data may identify age, period or cohort effects among perpetrators of assault.

scholarly journals Estimating LOCP cancer mortality rates in small domains in Spain using its relationship with lung cancer

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Garazi Retegui ◽  
Jaione Etxeberria ◽  
María Dolores Ugarte
Keyword(s):  
Lung Cancer ◽  
Cancer Mortality ◽  
Age Groups ◽  
Spatial Models ◽  
Target Population ◽  
Mortality Rates ◽  
Age Group ◽  
Close Link ◽  
The North ◽  
And Gender

AbstractThe distribution of lip, oral cavity, and pharynx (LOCP) cancer mortality rates in small domains (defined as the combination of province, age group, and gender) remains unknown in Spain. As many of the LOCP risk factors are preventable, specific prevention programmes could be implemented but this requires a clear specification of the target population. This paper provides an in-depth description of LOCP mortality rates by province, age group and gender, giving a complete overview of the disease. This study also presents a methodological challenge. As the number of LOCP cancer cases in small domains (province, age groups and gender) is scarce, univariate spatial models do not provide reliable results or are even impossible to fit. In view of the close link between LOCP and lung cancer, we consider analyzing them jointly by using shared component models. These models allow information-borrowing among diseases, ultimately providing the analysis of cancer sites with few cases at a very disaggregated level. Results show that males have higher mortality rates than females and these rates increase with age. Regions located in the north of Spain show the highest LOCP cancer mortality rates.

scholarly journals Trends in asthma mortality in the 0- to 4-year and 5- to 34-year age groups in Brazil

2017 ◽  
Vol 43 (1) ◽  
pp. 24-31 ◽  
Author(s):  
Gustavo Silveira Graudenz ◽  
Dominique Piacenti Carneiro ◽  
Rodolfo de Paula Vieira
Keyword(s):  
General Population ◽  
Inhaled Corticosteroids ◽  
Linear Trend ◽  
Age Groups ◽  
International Classification Of Diseases ◽  
Mortality Rates ◽  
Linear Decrease ◽  
Control Asthma ◽  
Classification Of Diseases ◽  
Asthma Mortality

ABSTRACT Objective: To provide an update on trends in asthma mortality in Brazil for two age groups: 0-4 years and 5-34 years. Methods: Data on mortality from asthma, as defined in the International Classification of Diseases, were obtained for the 1980-2014 period from the Mortality Database maintained by the Information Technology Department of the Brazilian Unified Health Care System. To analyze time trends in standardized asthma mortality rates, we conducted an ecological time-series study, using regression models for the 0- to 4-year and 5- to 34-year age groups. Results: There was a linear trend toward a decrease in asthma mortality in both age groups, whereas there was a third-order polynomial fit in the general population. Conclusions: Although asthma mortality showed a consistent, linear decrease in individuals ≤ 34 years of age, the rate of decline was greater in the 0- to 4-year age group. The 5- to 34-year group also showed a linear decline in mortality, and the rate of that decline increased after the year 2004, when treatment with inhaled corticosteroids became more widely available. The linear decrease in asthma mortality found in both age groups contrasts with the nonlinear trend observed in the general population of Brazil. The introduction of inhaled corticosteroid use through public policies to control asthma coincided with a significant decrease in asthma mortality rates in both subsets of individuals over 5 years of age. The causes of this decline in asthma-related mortality in younger age groups continue to constitute a matter of debate.

Mortality in hospitalized elderly from SUS in João Pessoa city – PB, from 2000 to 2007

2010 ◽  
Vol 4 (4) ◽  
pp. 1840
Author(s):  
Priscilla Medeiros Neves ◽  
Dyego Anderson Alves de Farias ◽  
Thatielle Vaz de Carvalho Rigão ◽  
Geraldo Eduardo Guedes de Brito ◽  
Kátia Suely Queiroz Silva Ribeiro
Keyword(s):  
Mortality Rate ◽  
Hospital Admissions ◽  
The Elderly ◽  
International Classification Of Diseases ◽  
Mortality Rates ◽  
Laboratory Findings ◽  
Classification Of Diseases ◽  
Icd 10 ◽  
And Gender ◽  
National Trends

ABSTRACTObjective: to determine the mortality profile in the elderly population in João Pessoa city - PB, underwent hospital admissions in the SUS from 2000 to 2007. Methodology: this is about a documentary study, from descriptive approach, which used data from the SIH/SUS referring to individuals over 60 years old. The studied variables were hospital mortality rate of the elderly people by age and gender, according to the chapters of the International Classification of Diseases (ICD-10). Results: according to the ICD-10 chapters, the illnesses that present the highest mortality rates in the elderly are: the endocrine ones, the ones with symptoms, signs and abnormal clinical and laboratory findings, the hematologic ones, blood-forming organs and certain disorders involving the immune mechanism, the infectious and parasitic ones, and the nervous system ones. It was observed that there aren´t significant differences between the genders and that rates increase with increasing age. Conclusion: the Paraiba’s capital follows the trend of other Brazilian cities, as well as the national trends regarding mortality rates related to gender, and, especially, related to age. Descriptors: aged; hospitalization; mortality rate; Single Health System; nursing.RESUMOObjetivo: traçar o perfil de mortalidade da população idosa da cidade de João Pessoa – PB, submetida a internações hospitalares no âmbito do SUS entre os anos de 2000 e 2007. Metodologia: estudo documental de natureza descritiva, que utilizou dados do SIH/SUS referente aos indivíduos com 60 anos e mais de idade.  As variáveis estudadas foram as taxas de mortalidade hospitalar de idosos por faixa etária e sexo, segundo os capítulos da Classificação Internacional de Doenças (CID-10). Resultados: as doenças, segundo os capítulos da CID—10, que apresentam as maiores taxas de mortalidade em idosos são: as endócrinas, as de sintomas, sinais e achados anormais de exames clínicos e laboratoriais, as hematológicas, dos órgãos hematopoéticos e transtornos imunitários, as infecciosas e parasitárias e as do sistema nervoso. Observou-se que não há diferenças significativas entre os sexos e que as taxas aumentam com o avançar da idade. Conclusão: a capital paraibana acompanha a tendência de outras cidades brasileiras, bem como a tendência nacional no que diz respeito às taxas de mortalidade, ao relacioná-las com o sexo, e principalmente com a idade. Descritores: idoso; hospitalização; taxa de mortalidade; Sistema Único de Saúde; enfermagem.RESÚMENObjetivo: trazar el perfil de mortalidad de la población anciana de la ciudad de João Pessoa, Paraíba, sometida a internaciones hospitalares en el ámbito del SUS entre los años de 2000 y 2007. Metodología: estudio documental, de naturaleza descriptiva, que utilizó datos del SIH/SUS referentes a los individuos con más de 60 años de edad.  Las variables estudiadas fueron la tasa de mortalidad hospitalar de ancianos por faja etaria y sexo, según los capítulos de la Clasificación Internacional de Enfermedades (CIE-10).  Resultados: las enfermedades, según los capítulos de la CIE—10, que presentan las más altas tasas de mortalidad en ancianos son las: endocrinas, las de síntomas, señales y hallazgos anormales de exámenes clínicos e laboratoriales, las hematológicas, de los órganos hematopoéticos y transtornos inmunitarios, las infecciosas y parasitarias y las del sistema nervioso. Se observo que no hay diferencias significativas entre los sexos y que las tasas aumentan progresivamente con la edad. Conclusión: la capital paraibana acompaña la tendencia de otras ciudades brasileñas, bien como la tendencia nacional en lo que respecta a las tasas de mortalidad, al relacionarlas con el sexo, y principalmente con la edad. Descriptores: anciano; hospitalización; tasa de mortalidad; Sistema Único de Salud; enfermería. 

scholarly journals International Analysis of Age-Specific Mortality Rates From Mesothelioma on the Basis of the International Classification of Diseases, 10th Revision

2018 ◽  
pp. 1-15 ◽  
Author(s):  
Paolo Boffetta ◽  
Matteo Malvezzi ◽  
Enrico Pira ◽  
Eva Negri ◽  
Carlo La Vecchia
Keyword(s):  
United States ◽  
Age Groups ◽  
International Classification Of Diseases ◽  
The United States ◽  
Mortality Rates ◽  
International Classification ◽  
Peritoneal Mesothelioma ◽  
Specific Mortality ◽  
Classification Of Diseases

Past analyses of mortality data from mesothelioma relied on unspecific codes, such as pleural neoplasms. We calculated temporal trends in age-specific mortality rates in Canada, the United States, Japan, France, Germany, Italy, the Netherlands, Poland, the United Kingdom, and Australia on the basis of the 10th version of the International Classification of Diseases, which includes a specific code for mesothelioma. Older age groups showed an increase (in the United States, a weaker decrease) during the study period, whereas in young age groups, there was a decrease (in Poland, a weaker increase, starting, however, from low rates). Results were consistent between men and women and between pleural and peritoneal mesothelioma, although a smaller number of events in women and for peritoneal mesothelioma resulted in less precise results. The results show the heterogeneous effect of the reduction of asbestos exposure on different age groups; decreasing mortality in young people reflects reduced exposure opportunity, and increasing mortality in the elderly shows the long-term effect of early exposures.

scholarly journals Garbage codes as causes of death and quality of mortality statistics in Belo Horizonte, Brazil

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
L Ishitani ◽  
R Teixeira ◽  
D Abreu ◽  
L Paixão ◽  
E França
Keyword(s):  
Causes Of Death ◽  
Health Planning ◽  
Age Groups ◽  
International Classification Of Diseases ◽  
Mortality Statistics ◽  
Classification Of Diseases ◽  
Icd 10 ◽  
Hospital Deaths ◽  
Belo Horizonte

Abstract Background Quality of cause-of-death information is fundamental for health planning. Traditionally, this quality has been assessed by the analysis of ill-defined causes from chapter XVIII of the International Classification of Diseases - 10th revision (ICD-10). However, studies have considered other useless diagnoses for public health purposes, defined, in conjunction with ill-defined causes, as garbage codes (GC). In Brazil, despite the high completeness of the Mortality Information System, approximately 30% of deaths are attributable to GCs. This study aims to analyze the frequency of GCs in Belo Horizonte municipality, the capital of Minas Gerais state, Brazil. Methods Data of deaths from 2011 to 2013 in Belo Horizonte were analyzed. GCs were classified according to the GBD 2015 study list. These codes were classified in: a) GCs from chapter XVIII of ICD-10 (GC-R), and b) GC from other chapters of ICD-10 (GC-nonR). Proportions of GC were calculated by sex, age, and place of occurrence. Results In Belo Horizonte, from the total of 44,123 deaths, 5.5% were classified as GC-R. The majority of GCs were GC-nonR (25% of total deaths). We observed a higher proportion of GC in children (1 to 4 years) and in people aged over 60 years. GC proportion was also higher in females, except in the age-groups under 1 year and 30-59 years. Home deaths (n = 7,760) had higher proportions of GCs compared with hospital deaths (n = 30,182), 36.9% and 28.7%, respectively. The leading GCs were the GC-R other ill-defined and unspecified causes of death (ICD-10 code R99)), and the GCs-nonR unspecified pneumonia (J18.9), unspecified stroke (I64), and unspecified septicemia (A41.9). Conclusions Analysis of GCs is essential to evaluate the quality of mortality information. Key messages Analysis of ill-defined causes (GC-R) is not sufficient to evaluate the quality of information on causes of death. Causes of death analysis should consider the total GC, in order to advance the discussion and promote adequate intervention on the quality of mortality statistics.

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