Serology Testing: The Dark Horse in SARS COV2 Pandemic

: COVID-19, an epidemic that emerged in Wuhan, has become a pandemic affecting worldwide and is in a rapidly evolving condition. Day by day, the confirmed cases and deaths are increasing many folds. SARS-CoV-2 is a novel virus; therefore, limited data are available to curb the disease. Epidemiological approaches, isolation, quarantine, social distancing, lockdown, and curfew are being employed to halt the spread of the disease. Individual and joint efforts all over the world are producing a wealth of data and information which are expected to produce therapeutic strategies against COVID-19. Current research focuses on the utilization of antiviral drugs, repurposing strategies, vaccine development as well as basic to advanced research about the organism and the infection. The review focuses on the life cycle, targets, and possible therapeutic strategies, which can lead to further research and development of COVID-19 therapy.

Download Full-text

Political Translation and the Sustainable Development Goals

The Oxford Handbook of Translation and Social Practices ◽

10.1093/oxfordhb/9780190067205.013.18 ◽

2020 ◽

pp. 169-188

Author(s):

Chris G. Pope ◽

Meng Ji ◽

Xuemei Bai

Keyword(s):

Sustainable Development ◽

Political Discourse ◽

Sustainable Development Goals ◽

Social Systems ◽

Political Process ◽

The Political ◽

Political Systems ◽

The Sustainable Development ◽

The World ◽

Development Goals

The chapter argues that whether or not the world is successful in attaining sustainability, political systems are in a process of epoch-defining change as a result of the unsustainable demands of our social systems. This chapter theorizes a framework for analyzing the political “translation” of sustainability norms within national polities. Translation, in this sense, denotes the political reinterpretation of sustainable development as well as the national capacities and contexts which impact how sustainability agendas can be instrumentalized. This requires an examination into the political architecture of a national polity, the norms that inform a political process, socioecological contexts, the main communicative channels involved in the dissemination of political discourse and other key structures and agencies, and the kinds of approaches toward sustainability that inform the political process. This framework aims to draw attention to the ways in which global economic, political, and social systems are adapting and transforming as a result of unsustainability and to further understanding of the effectiveness of globally diffused sustainability norms in directing that change.

Download Full-text

SARS-CoV-2 vaccines strategies: a comprehensive review of phase 3 candidates

npj Vaccines ◽

10.1038/s41541-021-00292-w ◽

2021 ◽

Vol 6 (1) ◽

Cited By ~ 3

Author(s):

Nikolaos C. Kyriakidis ◽

Andrés López-Cortés ◽

Eduardo Vásconez González ◽

Alejandra Barreto Grimaldos ◽

Esteban Ortiz Prado

Keyword(s):

Neutralizing Antibodies ◽

Large Scale ◽

Vaccine Development ◽

Rna Virus ◽

Protein S ◽

Effective Vaccine ◽

Phase 3 ◽

Vaccine Candidates ◽

Advantages And Disadvantages ◽

The World

AbstractThe new SARS-CoV-2 virus is an RNA virus that belongs to the Coronaviridae family and causes COVID-19 disease. The newly sequenced virus appears to originate in China and rapidly spread throughout the world, becoming a pandemic that, until January 5th, 2021, has caused more than 1,866,000 deaths. Hence, laboratories worldwide are developing an effective vaccine against this disease, which will be essential to reduce morbidity and mortality. Currently, there more than 64 vaccine candidates, most of them aiming to induce neutralizing antibodies against the spike protein (S). These antibodies will prevent uptake through the human ACE-2 receptor, thereby limiting viral entrance. Different vaccine platforms are being used for vaccine development, each one presenting several advantages and disadvantages. Thus far, thirteen vaccine candidates are being tested in Phase 3 clinical trials; therefore, it is closer to receiving approval or authorization for large-scale immunizations.

Download Full-text

3D Technology – Additive Manufacturing Applications and Prospects (Vol. 24, No. 9, Full Issue)

Asia-Pacific Biotech News ◽

10.1142/s0219030320001093 ◽

2020 ◽

Vol 24 (09) ◽

Keyword(s):

Additive Manufacturing ◽

3D Printing ◽

Environmental Impact ◽

Real World ◽

Vaccine Development ◽

Health Screening ◽

Wide Range ◽

The World ◽

Real World Applications ◽

Manufacturing Applications

For the month of September 2020, APBN dives into the world of 3D printing and its wide range of real-world applications. Keeping our focus on the topic of the year, the COVID-19 pandemic, we explore the environmental impact of the global outbreak as well as gain insight to the top 5 vaccine platforms used in vaccine development. Discover more about technological advancements and how it is assisting innovation in geriatric health screening.

Download Full-text

Vladimov's dog

Index on Censorship ◽

10.1080/03064228708534304 ◽

1987 ◽

Vol 16 (8) ◽

pp. 26-29

Author(s):

Karel Kyncl

Keyword(s):

Social Systems ◽

Soviet Bloc ◽

The World

‘One sometimes despairs of ever being able to convey the facts of life in the Soviet bloc to people living under different social systems, who judge the world by their own democratic and liberal standards’

Download Full-text

SARS-CoV-2: Molecular biology and therapeutic target.

Coronaviruses ◽

10.2174/2666796702666210225103821 ◽

2021 ◽

Vol 02 ◽

Author(s):

Vivek Pandey ◽

Ankita Pathak ◽

Mohammad Shahar Yar ◽

Yuba Raj Pokharel

Keyword(s):

Viral Genome ◽

Vaccine Development ◽

Viral Proteins ◽

Current Review ◽

The World ◽

Spanish Flu ◽

Repurposed Drugs ◽

Key Features ◽

Economic Infrastructure ◽

Viral Outbreak

: A century after the outbreak of the Spanish flu, the world is suffering with another pandemic on because of the coronavirus. The virus took a toll of more than millions of lives worldwide and still continues to affect the health and socio-economic infrastructure all over the world. The study explores the epidemiology, etiology and transmission of the virus and its phylogenetic relationship with SARS and MERS coronavirus responsible for 2002 and 2012 viral outbreak. Highlights about the key features of the viral genome and essential viral proteins responsible for viral life cycle, evading host immune response, and viral immunopathology with therapeutics from “Recovery” and “Solidarity” trials, are major concern of the current review. The review culminated with a discussion on different classes of front-runners vaccines and their efficacy. An overall understanding of essential viral proteins and their role in pathogenesis, repurposed drugs and vaccine development is the rationale of the present review.

Download Full-text

The 2016 Vaccine Development Pipeline: A special issue from the World Health Organization Product Development for Vaccine Advisory Committee (PDVAC)

Vaccine ◽

10.1016/j.vaccine.2016.04.041 ◽

2016 ◽

Vol 34 (26) ◽

pp. 2863-2864 ◽

Cited By ~ 10

Author(s):

Birgitte K. Giersing ◽

Kayvon Modjarrad ◽

David C. Kaslow ◽

Jean-Marie Okwo-Bele ◽

Vasee S. Moorthy

Keyword(s):

Product Development ◽

World Health Organization ◽

Advisory Committee ◽

Vaccine Development ◽

World Health ◽

Special Issue ◽

The World ◽

Development Pipeline ◽

Health Organization

Download Full-text

SOSIOLOGI SPIRITUALITAS & KESALEHAN SOSIAL

Spiritualita ◽

10.30762/spr.v4i2.2689 ◽

2020 ◽

Vol 4 (2) ◽

Author(s):

Sukron Romadhon

Keyword(s):

Economic System ◽

Social Systems ◽

Science And Technology ◽

Modern Society ◽

Economic Relations ◽

Religious Traditions ◽

Religious Rituals ◽

The People ◽

The World ◽

New Religion

Spirituality and a new religious awakening, are seen by religious elites as a stage of religious directness in carrying out religious traditions and rituals. New civilizations can instead be a threat to conventional religious traditions and rituals. Without the willingness of religious elites to criticize and re-interpret conventional ritual traditions and patterns, the functions of the world's major religions could fade. The world's major religions are increasingly alienated from the objective world and awareness of the lives of the people and their people. It seems that there will be a new form of religion or a new religion that is completely different from the tradition of religious rituals that have been carried out by the major religions of the world. While the religious elite is still attached to classical religious interpretations. But on the other hand, the emergence of modern society, encouraging the argument of secularization is part of modernization. The values underlying socio-political and economic relations also appear to be beginning to enter an irregular stage, when viewed conventionally, the spiritulitas of global civilization, rather than lies in the format of values, traditional systems and structures or modern rationality. New civilizations in social systems and Science and Technology (SCIENCE AND TECHNOLOGY) began to be directed at a more intuitive spirituality stage. Then came the act of social piety that proved impartiality over the duafa wal mustad'afin, workers and the poor who were oppressed by the economic system. The emergence of the term left theology only wants to explain about righteousness and belief based on the ability to perform acts of liberation of the proletariat. This action is not only done after the reality of the proletariat appears, but creates a social and economic system that has impartiality towards the proletariat.Keywords: Spirituality, Secularization, Social Piety

Download Full-text

Pilot Study Efektifitas Media Video Animasi Terhadap Tingkat Depresi Pasien Kanker Serviks Diagnosa Awal

Indonesian Journal of Nursing Research (IJNR) ◽

10.35473/ijnr.v2i1.225 ◽

2019 ◽

Vol 2 (1) ◽

Author(s):

Dwi Fitriyanti ◽

Mardiyono Mardiyono ◽

Yuriz Bakhtiar

Keyword(s):

Cervical Cancer ◽

Pilot Study ◽

Intervention Group ◽

Initial Diagnosis ◽

Rank Test ◽

Control Group ◽

The World ◽

Before And After ◽

Wilcoxon Sign Rank ◽

Depression Level

Cervical cancer is the cancer that most often attacks women after breastcancer throughout the world. Around the world every two minutes or everyhour a woman dies from cervical cancer. Every patient newly diagnosed withcervical cancer needs to know information about cervical cancer that canaffect the patient's psychological changes in the form of depression. Thepurpose of this study was to determine the effectiveness of education withanimation media to reduce the depression level of cervical cancer patientswith early diagnosis. The method of this research is a pilot study(preliminary study) or testing the feasibility of animation video media on thelevel of depression. Respondent samples in the animated video media trialincluded 10 intervention samples and 10 control samples. The results of theanimation video media research are feasible to be used in subsequent studiesin cervical cancer patients with an initial diagnosis of depression. Dataanalysis using the Wilcoxon Sign Rank Test showed that there was asignificant difference in the level of depression before and after being giveneducation using the animation video media in the intervention group with avalue of p = 0.005 while in the control group with a value p = 0.102. Theconclusion of this study is that the animation video media is feasible to beused in subsequent studies and can effectively be given to cervical cancerpatients with an initial diagnosis of depression.

Download Full-text