AN ANTI-INFLAMMATORY HERBAL FOR HEALTH AND DISEASES: SILYBUM MARIANUM (MILK THISTLE)

2020 ◽  
Vol 0 (37) ◽  
pp. 0-0
Author(s):  
Pırıl Ayris GÜRSİLİ ◽  
Burcu YEŞİLKAYA
Keyword(s):  
Bioactive Compounds ◽  
Human Body ◽  
Nutritional Value ◽  
Human Life ◽  
The Body ◽  
Noncommunicable Diseases ◽  
Natural Form ◽  
Herbal Products ◽  
Positive Effects ◽  
Anti Inflammatory

Aim: Life has changed very fast during last 10 years. The adaptation of sedentary life, changes of eating habbits and other negative environmental factors consisted of reactive oxygen species in the human body and causing immunity to weaken. The prevelance of chronic dieases are increased caused by this reason. To take precautions against increasing diseases and to stop their progress, too much medication usage has been observed. People who don’t want to use medicine, started to use natural herbal products. Herbals are essentials for life and diseases. Herbals have different and comlex compounds which can be a cure for a diease. It has been possible to benefit the body mechanism and diseases with antioxidant, anti-inflammatory and antifibrotic effects. Thistle is one of the major herbal that is used for both as a cure and a nutrient. Its nutritional value and the bioactive compounds are important for a human life. Method: Current studies reviewed to explain thistles with its nutritional value, bioactive compounds and effects on diseases. Result: The thistle has important role as a component of medicines and also the natural form itself has a huge nutritional value for health. Consclusion: thistle have a beneficial effect on human body to be treated naturally, and its benefits are focused on noncommunicable diseases. Treatment of most chronic diseases, they had the advantages to stop their healing, protection and progression against diseases. Many studies have had positive effects. however, more studies should be done.

scholarly journals From designing diets for animals to designing food of animal origin – overview

2021 ◽  
Vol 854 (1) ◽  
pp. 012056
Author(s):  
R Markovic ◽  
M Z Baltic ◽  
S Radulovic ◽  
D Peric ◽  
D Jovanovic ◽  
...  
Keyword(s):  
Human Health ◽  
Nutritional Value ◽  
Human Life ◽  
Standard Form ◽  
Daily Intake ◽  
The Body ◽  
Animal Origin ◽  
Positive Effects ◽  
Food Of Animal Origin ◽  
Positive Effect

Abstract In recent times, food is not only observed from the point of view of the required intake for growth, development and regeneration of the body, but also has a leading role in the quality of human life. Therefore, the diet focuses on optimizing the daily intake of both nutrients and non-nutritive ingredients of food, all in order to preserve health and, above all, reduce the risk of chronic non-communicable diseases. Functional food can be considered food that has been scientifically proven to have a positive effect on certain body functions (in addition to the usual nutritional value) that contribute to human health and reduce the risk of disease. At the same time, it is important that the food has a standard form and that the positive effect on health is manifested by consuming the usual amount of food. The functionality of food is achieved by the presence in it of bioactive components (one or more) which have been scientifically proven to have positive effects on human health in the quantities in which they are present in food. The nutritional value of foods of animal origin depends on many factors, but certainly animal diet has the greatest impact. In human nutrition the so-called designed products of animal origin (meat, milk, eggs) are used, which are due to the specific animal diets enriched with n-3 fatty acids, vitamins, carotenoids or trace elements. Today, there are nutritional strategies by which we can access functional foods for the purpose of health promotion.

An Overview of Novel Bioactive Compounds with Potent Anti-Inflammatory Activity via Dual COX-2 and 5-LOX Enzyme Inhibition

2021 ◽  
Vol 18 ◽  
Author(s):  
Roopal Mittal ◽  
Shailesh Sharma ◽  
Ajay Singh Kushwah
Keyword(s):  
Bioactive Compounds ◽  
Enzyme Inhibitors ◽  
World Health Organisation ◽  
The Body ◽  
Inflammatory Activity ◽  
World Health ◽  
Quality Data ◽  
The World ◽  
Cox 2 ◽  
Anti Inflammatory

Background: Inflammation is the earliest body defence mechanism in which the immune system recognises and counters the antigens and aids in healing the disease. The World Health Organisation suggests that inflammation is one of the greatest causes of death in the world. Inflammation could be acute or chronic due to the release of inflammatory mediators i.e. prostaglandins, leukotrienes due to mitogens, antigens or cytokines found in the body. Methods: Bibliographic database using pub med cites for peer-reviewed research articles with titles containing dual COX-2 and 5-LOX enzyme inhibitors, heterocyclic moieties, with AND Boolean operator's terms since last ten years of literature work. The quality papers containing the natural or synthetic lead compounds were extracted; the detailed study and conceptual framework attracted its attention. Results: Out of 127 research and review articles evaluated, 54 articles were cited to provide high quality data regarding pharmacoactive molecules having anti-inflammatory activity via dual COX-2/5-LOX inhibition. In addition, highlighting their in silico and experimental wet laboratory studies in increasing order over the past decade with the best illustration of dual enzyme inhibitory activity. Conclusion: This review gathered details of isolated bioactive compounds such as pyrazole, coumaperine, indoles, phenanthrene derivatives that have been significantly reported for anti-inflammatory activities.

Animality in Eschatological Transformation

2018 ◽  
pp. 146-172
Author(s):  
Eric Daryl Meyer
Keyword(s):  
Human Body ◽  
Human Life ◽  
The Body ◽  
Sexual Expression ◽  
Human Being ◽  
Eucharistic Theology ◽  
Vital Functions

Chapter 6 takes up the end of the human story with God, the eschatological transformation of the human being through the resurrection of the body end entry into perfect communion with God. Conventionally, theologians have imagined resurrected of human body as being whole and intact, but with several basic vital functions negated—namely digestion and sexual expression. Arguing that such a maneuver safeguards the materiality of the human body precisely by negating its animality, this chapter seeks to construct a vision of transformed human life with God in which digestion and sexual expression are at the center of human communion with God and fellow creatures. The chapter’s efforts are aided by the wealth of the tradition itself: biblical and liturgical imagery such as the wedding feast of the Lamb, eucharistic theology, and Christian nuptial mysticism.

scholarly journals Sargassum Seaweed as a Source of Anti-Inflammatory Substances and the Potential Insight of the Tropical Species: A Review

Marine Drugs ◽  
2019 ◽  
Vol 17 (10) ◽  
pp. 590 ◽  
Author(s):  
Saraswati ◽  
Puspo Edi Giriwono ◽  
Diah Iskandriati ◽  
Chin Ping Tan ◽  
Nuri Andarwulan
Keyword(s):  
Bioactive Compounds ◽  
Optimal Growth ◽  
The Body ◽  
Inflammatory Activity ◽  
Sulfated Polysaccharides ◽  
Tropical Species ◽  
Tropical Region ◽  
Inflammatory Conditions ◽  
Microbial Infections ◽  
Anti Inflammatory

Sargassum is recognized both empirically and scientifically as a potential anti-inflammatory agent. Inflammation is an important response in the body that helps to overcome various challenges to body homeostasis such as microbial infections, tissue stress, and certain injuries. Excessive and uncontrolled inflammatory conditions can affect the pathogenesis of various diseases. This review aims to explore the potential of Sargassum’s anti-inflammatory activity, not only in crude extracts but also in sulfated polysaccharides and purified compounds. The tropical region has a promising availability of Sargassum biomass because its climate allows for the optimal growth of seaweed throughout the year. This is important for its commercial utilization as functional ingredients for both food and non-food applications. To the best of our knowledge, studies related to Sargassum’s anti-inflammatory activity are still dominated by subtropical species. Studies on tropical Sargassum are mainly focused on the polysaccharides group, though there are some other potentially bioactive compounds such as polyphenols, terpenoids, fucoxanthin, fatty acids and their derivatives, typical polar lipids, and other groups. Information on the modulation mechanism of Sargassum’s bioactive compounds on the inflammatory response is also discussed here, but specific mechanisms related to the interaction between bioactive compounds and targets in cells still need to be further studied.

scholarly journals Rosmarinic Acid–Human Pharmacokinetics and Health Benefits

Planta Medica ◽  
2020 ◽  
Author(s):  
Maja Hitl ◽  
Nebojša Kladar ◽  
Neda Gavarić ◽  
Biljana Božin
Keyword(s):  
Human Body ◽  
Rosmarinic Acid ◽  
Structural Changes ◽  
Wide Spectrum ◽  
Health Benefits ◽  
The Body ◽  
Herbal Remedies ◽  
Future Research ◽  
Human Pharmacokinetics ◽  
Positive Effects

AbstractRosmarinic acid is a phenolic compound commonly found in the Lamiaceae (Labiateae) plant species. It is considered responsible for a wide spectrum of biological and pharmacological activities of plants containing this compound. The aim of the current review is to present the fate of rosmarinic acid inside the human body, explained through pharmacokinetic steps and to briefly present the health benefits of RA. Pharmacokinetics was at first studied in animal models, but several studies were conducted in humans as well. This compound can be applied topically, pulmonary, intranasally, and via intravenous infusion. However, peroral application is the main route of entry into the human body. Presumably, it is mainly metabolized by the gut microflora, providing simple, more easily absorbed phenolic units. Inside the body, the rosmarinic acid molecule undergoes structural changes, as well as conjugation reactions. Renal excretion represents the main path of elimination. Previously conducted studies reported no serious adverse effects of herbal remedies containing RA, as well as their positive effects on human health. In addition to in vitro studies, clinical investigations suggested its benefits in dermatological, allergic, and osteoarthritic disorders, as well as for improving cognitive performance and in metabolic syndrome treatment. Future studies should investigate the kinetics during long-term application in patients who would have potential benefits from RA usage. Pharmaceutical formulations designed to prevent the fast metabolism of RA and allow its penetration into other compartments of the human body are also interesting topics for future research.

scholarly journals Microbiocenosis Of Open Cavities Of The Body

2021 ◽  
Vol 03 (07) ◽  
pp. 1-45
Author(s):  
Ziyaeva E.R. ◽  
Keyword(s):  
Environmental Pollution ◽  
Human Body ◽  
Human Life ◽  
The Body ◽  
Chemotherapeutic Drugs ◽  
Topical Problem ◽  
Normal Microflora ◽  
Open Cavities

The article is devoted to a review of the topical problem of our time “Microbiocenosis of open cavities of the body and its role in the occurrence of many diseases of the human body ”. It has now been proven that the normal microflora of the human body plays a huge role in the normal course of life processes. The slightest violation of the composition of microorganisms leads to various irreversible defects in the normal course of human life, which are associated with the functions of the microbiocenosis and which no medicine can replace. The concept of microbiocenosis appeared in the 70s of the last century, although the first stone in this direction was put by Louis Pasteur, who proved the role of a microorganism in the process of fermentation and digestion. Many scientists contributed to the leap forward development of this science, which was forced due to errors in the use of antibiotics and chemotherapeutic drugs. Yes, indeed, the path of development of the science of biocenoses is closely related to the misuse of drugs, which often leads to dysbiosis. In addition, environmental pollution due to the uncontrollable development of urbanization plays a huge role in the development of dysbiotic processes.Therefore, with the aim of acquainting readers with the concept of biocenoses, certain pathways of pathogenetic links in the development of various diseases in violation of the composition of the normal microflora of the human body, we set ourselves the task of conducting a partial review of the achievement of the science of biocenoses of open cavities of the body.

scholarly journals Application of Gadamerian Hermeneutics in Medicine based on the Meaning of Mulla Sadra's Truth

2021 ◽  
Vol 8 (10) ◽  
pp. 160
Author(s):  
Yousef Kheire ◽  
Seyyed Mohammad Amin Madayen
Keyword(s):  
Human Body ◽  
Human Life ◽  
Medical Science ◽  
The Body ◽  
Layer By Layer ◽  
Risk Of Death ◽  
Mulla Sadra ◽  
Patient At Risk ◽  
The Universe ◽  
Origin Of The Universe

Hermeneutics has been introduced as a science of Tafsīrand Ta’wīland this science emphasizes human understanding. Various fields related to the fields of human life and human civilization are the fields of study of this science. the different realms of hermeneutics in the field of medical science requires special delicacy and precision; because any inconsistency of the doctor's understanding with the truth of the disease puts the patient at risk of death. The present article, by descriptive and analytical methods, has applied Gadamerian hermeneutics based on Mulla Sadra's explanation of the truth with the topics of medical hermeneutics. Gadamerian method of medical hermeneutics has paid special attention to understanding the disease due to the importance of human life, and according to this method, both the physician and the patient participate in achieving the nature of the disease according to a dialogical and two-way model. Understanding the truth of the disease follows understanding the truth of the human body; and since the truth of the body, according to Mulla Sadra, depends on the truth of the soul and it also depends on the origin of the universe, which has infinite perfections, then the truth of the human body is unlimited. In short, the physician and the patient proceed through a dialogical relationship to a layer-by-layer understanding of the truth of the disease.

scholarly journals Allegories of life, death and immortality in the book of Ecclesiastes 12:5b–7

2019 ◽  
Vol 13 (1) ◽  
pp. 48-57 ◽  
Author(s):  
Igor Tantlevskij
Keyword(s):  
Olive Oil ◽  
Old Age ◽  
Human Body ◽  
Human Life ◽  
The Body ◽  
Eternal Life ◽  
Natural Phenomena ◽  
Life Activity ◽  
Golden Bowl ◽  
The Golden Bowl

Analyzing the famous passage Eccl. 12:5b–7, the author of the article comes to the conclusion that the expression "the almond tree blossomed" (12:5bα) contains the allegory of man’s birth and his young years; the phrase "the locust/locust tree became loaded" (12:5bβ) can be interpreted as an indication of the mature, productive/fruitful years of human life activity; the allegory of the caper, falling to winter ("and the caper bush fell"; 12:5bγ), correlates with the metaphorical description of old age and the approach of death in Eccl. 12:1b–2. So, one can assume that the passage Eccl. 12:5bα–γ includes the allegories of man's earthly birth, making up of his personality, maturity and old age in the form of natural phenomena that take place in Judea throughout the year — approximately from the second half of January to December. The allegory of the breaking "silver cord" (Eccl. 12:6aα), symbolizing the earthly demise, can be understood as a break in the connection between the spirit and the flesh of man (cf.: Eccl. 12:7). In 12:6аβ–b, Ecclesiastes adduces the allegories of death, expressed through the broken vessels ("golden bowl", "jar", a certain "vessel"), symbolizing the human body. The context also suggests that an allusion to the human spirit implicitly present in these allegories as well, which is symbolized by olive oil (in the "golden bowl") and water (in the "jar" and in the "vessel"), – not directly called, but contextually implied – returning to their eternal Fountain (cf.: Jer. 2:13, 17:13, also: Ps. 36:10) when their temporary receptacles are broken. The "spring" and the "well" (Eccl. 12:6b) are veritable symbols of life, and in the light of Eccl. 12:7b – perhaps symbols of eternal life in the Book of Ecclesiastes. As for the allegory of "the golden bowl", it clearly goes back to Zech. 4:2–3. In the light of the allegorical picture attested in Zech., chap. 4, and the text of Eccl. 12:7b, the allegory of Eccl. 12:6aβ – "the golden bowl will crack" – can presuppose implicitly not only the death of the body/"the golden bowl", but also that its contents – "oil", symbolizing the spirit abided in the body – will merge with the "oil" of the Divine Luminary, scil., with the Spirit of God.

scholarly journals Bioactive Compounds of Edible Fruits with Their Anti-Aging Properties: A Comprehensive Review to Prolong Human Life

Antioxidants ◽  
2020 ◽  
Vol 9 (11) ◽  
pp. 1123
Author(s):  
Rajni Dhalaria ◽  
Rachna Verma ◽  
Dinesh Kumar ◽  
Sunil Puri ◽  
Ashwani Tapwal ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Human Life ◽  
Antioxidant Properties ◽  
Living Organism ◽  
The Body ◽  
Cancer Type ◽  
Healthy Foods ◽  
Age Related ◽  
Dietary Nutrients ◽  
Health Promoting

Aging is a complicated biological process in which functional and structural alterations in a living organism take place over time. Reactive oxygen species is one of the main factors responsible for aging and is associated with several chronic pathologies. The relationship between aging and diet is quite interesting and has attained worldwide attention. Healthy food, in addition to dietary antioxidants, are required to delay the process of aging and improve the quality of life. Many healthy foods such as fruits are a good source of dietary nutrients and natural bioactive compounds which have antioxidant properties and are involved in preventing aging and other age-related disorders. Health benefits linked with healthy consumption of fruit have drawn increased interest. A significant number of studies have documented the advantages of fruit intake, as it suppresses free-radical development that further reduces the oxidative stress created in the body and protects against several types of diseases such as cancer, type 2 diabetes, inflammatory disorders, and other cardiovascular diseases that ultimately prevent aging. In addition, fruits have numerous other properties like anti-inflammatory, anti-cancerous, anti-diabetic, neuroprotective, and have health-promoting effects. Mechanisms of various bioactive compounds that aids in preventing various diseases and increases longevity are also described. This manuscript provides a summary of various bioactive components present in fruits along with their health-promoting and antiaging properties.

scholarly journals Fungi and Algae as Sources of Medicinal and Other Biologically Active Compounds: A Review

Nutrients ◽  
2021 ◽  
Vol 13 (9) ◽  
pp. 3178
Author(s):  
Joanna Ślusarczyk ◽  
Edyta Adamska ◽  
Joanna Czerwik-Marcinkowska
Keyword(s):  
Bioactive Compounds ◽  
Nutritional Value ◽  
Human Life ◽  
Pharmaceutical Preparations ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Lichenized Fungi ◽  
Food Sources ◽  
Active Compounds ◽  
Therapeutic Properties

Many species of fungi including lichenized fungi (lichens) and algae have the ability to biosynthesize biologically active compounds. They produce, among others, polysaccharides with anticancer and immunostimulatory properties: (1) Background: This paper presents the characteristics of the most important bioactive compounds produced by fungi and algae; (2) Methods: Based on the example of the selected species of mushrooms, lichens and algae, the therapeutic properties of the secondary metabolites that they produce and the possibilities of their use are presented; (3) Results: The importance of fungi, especially large-fruited mushrooms, lichens and algae, in nature and human life is discussed, in particular, with regard to their use in the pharmaceutical industry and their nutritional value; (4) Conclusions: The natural organisms, such as fungi, lichenized fungi and algae, could be used as supplementary medicine, in the form of pharmaceutical preparations and food sources. Further advanced studies are required on the pharmacological properties and bioactive compounds of these organisms.

Sign in / Sign up

Export Citation Format

Share Document