scholarly journals Bioactive Compounds of Edible Fruits with Their Anti-Aging Properties: A Comprehensive Review to Prolong Human Life

Antioxidants ◽  
2020 ◽  
Vol 9 (11) ◽  
pp. 1123
Author(s):  
Rajni Dhalaria ◽  
Rachna Verma ◽  
Dinesh Kumar ◽  
Sunil Puri ◽  
Ashwani Tapwal ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Human Life ◽  
Antioxidant Properties ◽  
Living Organism ◽  
The Body ◽  
Cancer Type ◽  
Healthy Foods ◽  
Age Related ◽  
Dietary Nutrients ◽  
Health Promoting

Aging is a complicated biological process in which functional and structural alterations in a living organism take place over time. Reactive oxygen species is one of the main factors responsible for aging and is associated with several chronic pathologies. The relationship between aging and diet is quite interesting and has attained worldwide attention. Healthy food, in addition to dietary antioxidants, are required to delay the process of aging and improve the quality of life. Many healthy foods such as fruits are a good source of dietary nutrients and natural bioactive compounds which have antioxidant properties and are involved in preventing aging and other age-related disorders. Health benefits linked with healthy consumption of fruit have drawn increased interest. A significant number of studies have documented the advantages of fruit intake, as it suppresses free-radical development that further reduces the oxidative stress created in the body and protects against several types of diseases such as cancer, type 2 diabetes, inflammatory disorders, and other cardiovascular diseases that ultimately prevent aging. In addition, fruits have numerous other properties like anti-inflammatory, anti-cancerous, anti-diabetic, neuroprotective, and have health-promoting effects. Mechanisms of various bioactive compounds that aids in preventing various diseases and increases longevity are also described. This manuscript provides a summary of various bioactive components present in fruits along with their health-promoting and antiaging properties.

AN ANTI-INFLAMMATORY HERBAL FOR HEALTH AND DISEASES: SILYBUM MARIANUM (MILK THISTLE)

2020 ◽  
Vol 0 (37) ◽  
pp. 0-0
Author(s):  
Pırıl Ayris GÜRSİLİ ◽  
Burcu YEŞİLKAYA
Keyword(s):  
Bioactive Compounds ◽  
Human Body ◽  
Nutritional Value ◽  
Human Life ◽  
The Body ◽  
Noncommunicable Diseases ◽  
Natural Form ◽  
Herbal Products ◽  
Positive Effects ◽  
Anti Inflammatory

Aim: Life has changed very fast during last 10 years. The adaptation of sedentary life, changes of eating habbits and other negative environmental factors consisted of reactive oxygen species in the human body and causing immunity to weaken. The prevelance of chronic dieases are increased caused by this reason. To take precautions against increasing diseases and to stop their progress, too much medication usage has been observed. People who don’t want to use medicine, started to use natural herbal products. Herbals are essentials for life and diseases. Herbals have different and comlex compounds which can be a cure for a diease. It has been possible to benefit the body mechanism and diseases with antioxidant, anti-inflammatory and antifibrotic effects. Thistle is one of the major herbal that is used for both as a cure and a nutrient. Its nutritional value and the bioactive compounds are important for a human life. Method: Current studies reviewed to explain thistles with its nutritional value, bioactive compounds and effects on diseases. Result: The thistle has important role as a component of medicines and also the natural form itself has a huge nutritional value for health. Consclusion: thistle have a beneficial effect on human body to be treated naturally, and its benefits are focused on noncommunicable diseases. Treatment of most chronic diseases, they had the advantages to stop their healing, protection and progression against diseases. Many studies have had positive effects. however, more studies should be done.

scholarly journals Differences in Bioactive Protein and Vitamin Status of Milk Obtained from Polish Local Breeds of Cows

2020 ◽  
Vol 20 (1) ◽  
pp. 287-298 ◽  
Author(s):  
Aneta Brodziak ◽  
Jolanta Król ◽  
Joanna Barłowska ◽  
Zygmunt Litwińczuk ◽  
Anna Teter ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Whey Proteins ◽  
Antioxidant Properties ◽  
Antimicrobial Properties ◽  
Processing Plant ◽  
Vitamin Status ◽  
Holstein Friesian ◽  
Health Promoting ◽  
Β Lactoglobulin ◽  
Β Carotene

AbstractThe aim of the study was to compare the content of selected bioactive whey proteins and lipophilic vitamins, which largely determine the bioactive status of milk, in milk obtained from local breeds of cows raised in Poland (Polish Red, White-Backed and Simmental) and Polish Holstein-Friesian cows. Basic chemical composition and content of selected bioactive compounds (β-lactoglobulin, α-lactalbumin, lactoferrin, bovine serum albumin, and vitamins: E, A, D3 and β-carotene) in 550 milk samples were analysed. The milk produced by local breeds proved to be a more valuable source of whey proteins and lipophilic vitamins than that of the Polish Holstein-Friesians. It was distinguished by its content of all bioactive compounds, including those with antioxidant properties, i.e. vitamins E, A and D3 and β-lactoglobulin, and antimicrobial properties, mainly lactoferrin. Therefore, the milk of cows of local breeds should be considered a valuable material for processing, especially at the level of the farm or small local processing plant, to produce products that are richer in health-promoting compounds. The promotion of milk from local breeds can therefore be an opportunity for the farms that raise them.

Antioxidant Capacity, Phytochemical Analysis and Identification of Active Compounds in Anchomanes difformis

2020 ◽  
Vol 10 (4) ◽  
pp. 446-458 ◽  
Author(s):  
Toyin Dorcas Alabi ◽  
Nicole Lisa Brooks ◽  
Oluwafemi Omoniyi Oguntibeju
Keyword(s):  
Antioxidant Capacity ◽  
Bioactive Compounds ◽  
Microbial Growth ◽  
Antioxidant Properties ◽  
Natural Antioxidants ◽  
Therapeutic Agents ◽  
Phytochemical Analysis ◽  
Flavonoid Content ◽  
The Family ◽  
Health Promoting

Background: Anchomanes difformis (ENGL: Blume) is a specie of flowering plants in the family Araceae. Anchomanes difformis is commonly reported for ameliorating hyperglycemia, inflammation, ulcer, malaria, and inhibiting microbial growth. Objective: This study evaluated total yields of phytochemicals present, measured antioxidant capacities and identified bioactive compounds in the leaves and rhizome extracts of A. difformis using solvents of different polarity (ethyl acetate, ethanol and water). Methods: Total polyphenolic, flavonoid content and alkaloids were measured, ORAC, TEAC and FRAP were performed as antioxidant capacity indices, and identification of bioactive compounds was done using UPLC-MS and HPLC. Results: All extracts contained polyphenols, flavonols, flavanols, and alkaloids in varying concentrations. All extracts exhibited antioxidant properties. However, aqueous leaves extract had the highest antioxidant properties and polyphenols with significance (p<0.05). Thirty-four compounds were identified altogether in the leaves and rhizome. Conclusion: A. difformis leaves and rhizome are potential sources of natural antioxidants and can serve as potential therapeutic agents against diseases linked with oxidative stress. Presence of health-promoting compounds indicates possible ameliorative potentials of A. difformis.

scholarly journals Immature Pear Extract Constituents Exert Multifaceted Anti-aging Effects

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 684-684
Author(s):  
Akira Ogita ◽  
Wakae Murata ◽  
Ken Yamauchi ◽  
Akiko Sakai ◽  
Yoshihiro Yamaguchi ◽  
...  
Keyword(s):  
Gene Expression ◽  
Cellular Senescence ◽  
Mammalian Cells ◽  
Human Life ◽  
The Body ◽  
Yeast Cells ◽  
Related Gene ◽  
Aging Effects ◽  
Chronological Lifespan ◽  
Age Related

Abstract Cellular senescence causes a gradual loss of physiological functions and induces chronic diseases, which negatively affect the quality of human life. Intervention in the cellular senescence process may reduce the incidence of these diseases while delaying the progression of age-related diseases, thereby prolonging human lifespan. In our previous study, we found that extending the chronological lifespan of budding yeast cells, a suitable cellular model for research on mammalian cells, could be achieved by adding immature pear extract (iPE). Moreover, at the 2020 GSA meeting, using a colony-counting method, we reported that both hydrophilic (WiPE) and hydrophobic (OiPE) iPE components exhibited a chronological lifespan prolongation on yeast cells. In this study, the expression of sirtuin-related genes, which regulate cellular senescence, was verified by quantitative real-time reverse-transcription polymerase chain reaction. Interestingly, sirtuin-related gene expression was significantly increased in the WiPE-treated cells only, and OiPE could extend the chronological lifespan of yeast cells through the mechanisms not involved in sirtuin-related gene expression. In general, hydrophobic and hydrophilic components exhibit different degradation and metabolism in cells. Since each component has a different strategy of absorption and excretion in the body, we hypothesize that iPE with multiple active components will have multifaceted effects on anti-aging. Our research on elucidating the mechanism of lifespan extension by OiPE and its application to mammalian cells is ongoing.

scholarly journals Prevalence, knowledge and perception of insomnia and hypersomnia condition among young adult population – A questionnaire-based survey

2020 ◽  
Vol 11 (SPL3) ◽  
pp. 1881-1887
Author(s):  
Sushma B ◽  
Karthik Ganesh Mohanraj
Keyword(s):  
Sampling Method ◽  
Human Life ◽  
Adult Population ◽  
The Body ◽  
Related Disorder ◽  
Age Related ◽  
Falling Asleep ◽  
Prolonged Duration ◽  
Young Adult Population ◽  
The Right

In the present modern mechanical world, humans are living like a machine without proper food at the right time, without sleep at the right time or even without any relaxation. There is a concept that even food stands next to sleep for a human's life. Sleep plays a major role in human life for the proper functioning of the brain. Any disturbances in sleep for prolonged duration or period may create serious effects in the body and its functioning. Sleeplessness is known clinically as insomnia, a sleep-related disorder wherein the affected people have problems in sleeping. They may have difficulty falling asleep or staying asleep as long as desired. Hypersomnia, on the other hand, is a neurological disorder of excessive times spent sleeping or excessive sleep. It can have many possible causes and problems with functioning. The study setting is done using online Google forms, including 100 participants. The sampling method is a random sampling method. Well-structured questionnaires were prepared and circulated among those 100 participants. According to the results, 74% of the adults who took the survey are aware that insomnia is sleeplessness. More than 50% of the adults feel that insomnia and hypersomnia lead to death, and 53% of the adults believe that insomnia and hypersomnia are age-related. It can be concluded that awareness of such sleep disorders can be helpful for future generations.

scholarly journals Antioxidant and other health promoting properties of herbs

2018 ◽  
Vol 116 (3) ◽  
pp. 23-33
Author(s):  
Małgorzata Dula ◽  
Jan Matras ◽  
Eugeniusz R. Grela ◽  
Ignacy Niedziółka
Keyword(s):  
Free Radicals ◽  
Fruits And Vegetables ◽  
Antioxidant Properties ◽  
The Body ◽  
Antioxidant Potential ◽  
Natural Food ◽  
Oxidation Reactions ◽  
Food Ingredients ◽  
Health Promoting ◽  
The One

Many component contained in the plants we usually eat are characterized by antioxidant properties, for example polyphenols effectively neutralize free radicals and other reactive oxygen species. The antioxidant potential of some herbal plants is many times higher than that of fruits and vegetables and therefore there has been a growing interest in the active substances contained therein. An improper diet, such as the one rich in lipids, adversely affects the level of free radicals in the body; so it is very important to choose to eat foods with a high antioxidant potential. The oxidation reactions that occur in food products have a detrimental impact on their nutritional value and sensory properties, such as taste, smell, color and texture. Antioxidants added to food can effectively counteract those changes, therefore there are sought natural food ingredients with antioxidant properties to replace synthetic antioxidants, such as BHA, BHT, which are often used in food. Some herbal spices have an anti-inflammatory and antibacterial effect. Moreover, they can stimulate appetite, increase the secretion of digestive juices and improve the absorption of nutrients. A diet enriched with suitable herbs or preparations obtained from them, mainly owing to the antioxidants contained therein, improves the functioning of the organism and prevents the development of certain diseases, such as cancer or atherosclerosis of blood vessels.

scholarly journals MORINGA OLEIFERA - FOOD AND MEDICINE FOR THE MODERN WORLD - MINI REVIEW

2019 ◽  
Vol 34 (4) ◽  
pp. 1081-1087
Author(s):  
Vasilka Ilieva
Keyword(s):  
Tamil Nadu ◽  
Moringa Oleifera ◽  
Neuroprotective Effect ◽  
Human Life ◽  
Antioxidant Properties ◽  
The Philippines ◽  
Ancient Egypt ◽  
Living Environment ◽  
The Body ◽  
Modern World

The Challenges of Modernity - Stress, Obesity, Socially Significant Diseases require the search for opportunities for prevention and treatment through sources of nature. In the food chain of modern man there is a total shortage of "living photons" from the sun, nutrients supplied by primordial sources residing in the natural environment, giving the cell both nutritional and energy resources and information from the living environment of the plant world. Overweight, metabolic syndrome and the resulting complications such as hypertension, atherosclerosis and diabetes have been proven to be linked to the modern diet. It is a source of substances that support inflammatory processes in the body. Hippocrates has also said that food is our medicine. The Moringa oleifera plant has features that attract the attention of science from different fields. Moringa oleifera is grown in tropical and subtropical regions at an altitude of 0 to 2000 meters. The plant prefers well-drained clay and sandy soils. The birthplace of Moringa oleifera is the southern foothills of the Himalayas. The plant is widely cultivated in India. The leaders in the Moringa industry are Andhra Pradesh, Karnataka and Tamil Nadu. It is also cultivated in Africa, Thailand, the Philippines, Indonesia, Haiti and Taiwan, Southeast Asia, some US states, including Hawaii and various countries in Oceania, as well as in Peru, Paraguay, the Pacific, the Caribbean and South America. Traditionally, in these areas, the plant is used as food and medicine. In many poor regions, Moringa oleifera is a food source of proteins, vitamins and minerals. Moringa oleifera is used in traditional medicine in many societies as a medicine. The Ayurvedic healing system uses the plant to treat 300 diseases. In addition to food and medicine, Moringa oleifera is used to purify water in areas without drinking water sources, to produce oil that is used as a lubricant, as well as in paint. In ancient Egypt, it was prized for its moisturizing properties and later used by the Romans. It is known as a cosmetic for skin rejuvenation and production of perfumes and soaps. Moringa oleifera can be considered an important functional food - a source of substances important to the human body. The unusual properties and wide application of the plant in various fields of human life are of high scientific interest. The ability of Moringa oleifera to influence many of the present-day disease states has been proven. Almost all parts from Moringa can be used as a source for nutrition with other useful values.It has antioxidant properties, which are the basis of anti-inflammatory, anti-cancer effects, anti-dyslipidemic effect, effects of type 2 diabetes, anti-asthmatic, antibacterial, neuroprotective effect.

Therapeutic and Nutraceutical Potential of Bioactive Compounds in Aegle marmelos (L.): An Overview

2019 ◽  
Vol 15 (4) ◽  
pp. 306-317
Author(s):  
Ena Gupta ◽  
Snehlata Shakyawar ◽  
Shanthy Sundaram
Keyword(s):  
Bioactive Compounds ◽  
Potential Role ◽  
Antioxidant Properties ◽  
Natural Antioxidants ◽  
Review Article ◽  
Aegle Marmelos ◽  
Prevention And Treatment ◽  
History Of ◽  
Health Promoting ◽  
Anti Fungal

Aegle Marmelos (L.) Correa (A. marmelos), is a medicinal plant of Rutaceae family having a long history of curative property in traditional medicine. This plant is a rich source of bioactive compounds and natural antioxidants which can be isolated from its various parts such as fruit (carotenoids, tannins, flavonoids, ascorbic acid, marmelosin, marmelide, psoralen, aurapten, luvangetin); leaf (phenols, lupeol, skimmianine, citral, aegeline, eugenol, citronella, marmesinine) and bark (marmin, skimmianine, fagarine) etc. Many clinical and pre-clinical researches suggest the therapeutic applications of A. marmelos, such as anti-bacterial, anti-fungal, anti-viral, anti-ulcer, anti-diabetic, anticancer, anti-inflammatory and antioxidant properties which play a potential role in the prevention and treatment of various diseases. This review article focuses on exploring novel bioactive compounds of the above plant possessing potential therapeutic and health promoting applications.

The influence of osteopathic correction on the rate of various rhythms of the body

2019 ◽  
pp. 64-71 ◽  
Author(s):  
A. E. Chernikova ◽  
Yu. P. Potekhina
Keyword(s):  
Heart Rate ◽  
Respiratory Rate ◽  
Age Groups ◽  
Biomechanical Properties ◽  
Dispersion Analysis ◽  
The Body ◽  
Body Tissues ◽  
Age Related ◽  
Significant Difference ◽  
Before And After

Introduction. An osteopathic examination determines the rate, the amplitude and the strength of the main rhythms (cardiac, respiratory and cranial). However, there are relatively few studies in the available literature dedicated to the influence of osteopathic correction (OC) on the characteristics of these rhythms.Goal of research — to study the influence of OC on the rate characteristics of various rhythms of the human body.Materials and methods. 88 adult osteopathic patients aged from 18 to 81 years were examined, among them 30 men and 58 women. All patients received general osteopathic examination. The rate of the cranial rhythm (RCR), respiratory rate (RR) heart rate (HR), the mobility of the nervous processes (MNP) and the connective tissue mobility (CTM) were assessed before and after the OC session.Results. Since age varied greatly in the examined group, a correlation analysis of age-related changes of the assessed rhythms was carried out. Only the CTM correlated with age (r=–0,28; p<0,05) in a statistically significant way. The rank dispersion analysis of Kruskal–Wallis also showed statistically significant difference in this indicator in different age groups (p=0,043). With the increase of years, the CTM decreases gradually. After the OC, the CTM, increased in a statistically significant way (p<0,0001). The RCR varied from 5 to 12 cycles/min in the examined group, which corresponded to the norm. After the OC, the RCR has increased in a statistically significant way (p<0,0001), the MNP has also increased (p<0,0001). The initial heart rate in the subjects varied from 56 to 94 beats/min, and in 15 % it exceeded the norm. After the OC the heart rate corresponded to the norm in all patients. The heart rate and the respiratory rate significantly decreased after the OC (р<0,0001).Conclusion. The described biorhythm changes after the OC session may be indicative of the improvement of the nervous regulation, of the normalization of the autonomic balance, of the improvement of the biomechanical properties of body tissues and of the increase of their mobility. The assessed parameters can be measured quickly without any additional equipment and can be used in order to study the results of the OC.

PERMEABILITY OF CELLS AND ITS IMPORTANCE IN ASSESSMENT OF FISHES AGE

1970 ◽  
pp. 70-73
Author(s):  
N. I. Maslova
Keyword(s):  
Cholesterol Content ◽  
The Body ◽  
Cellular Structures ◽  
Ratio Estimation ◽  
Carbohydrate Diet ◽  
Spawning Period ◽  
Age Related ◽  
Experimental Base ◽  
Cellular Permeability ◽  
Membrane Strength

The article presents analysis of material and results of their own studies on changes in the permeability of cellular structures, organs and tissues in carp, which is of great importance in determining age-related indicators. The cells permeability in liver and gonads estimation was carried out under the experimental base of VNIIR on two carp genotypes during the pre-spawning period. The carp groups taken for analysis differed significantly in their genotypes. In females of the Khrapunov group the fecundity was 2023.0 thousand units, while the number of oocytes filled with yolk was only 0.7%, in the Ostashevsky ones - 1370.0 thousand units and 8.6%, respectively. During estimation the chemical composition of the generative tissue in females and males it was established that the cholesterol and lecithin content in males is higher than that of females, while feeding dependence is observed, especially on the amount of protein in the diet. For example, in females on protein diet contained less glycogen in gonads than on females on carbohydrate diet. Lecithin and cholesterol are higher in males than in females, which corresponds to increasing the Gyurdy Ratio (estimation of cell membrane strength). In spermatogenesis the content of phospholipids and cholesterol in the liver was decreased less than during ovogenesis. This indicates a lower level of synthetic processes in the milts compared with the ovaries. The cholesterol content in sperm is higher than in caviar in 19.6 times, and phospholipids almost doubled. With increasing age, the Gyordy Ratio for caviar decreases, for sperm it increases, the percentage of caviar fertilization increases. As the body age metabolism deteriorates, cellular permeability decreases (the ratio of lecithin and cholesterol changes significantly). At the same time, the permeability of cells in different organs and tissues varies and depends on living conditions, especially feeding and to some extent on the origin. In fish the gross productivity decreases as growth slows down and more energy is spent on adaptation to environmental conditions.

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