scholarly journals Assessing chemical elements balance in patients with hypertension

2016 ◽  
Vol 97 (4) ◽  
pp. 501-507 ◽  
Author(s):  
I U Tarmaeva ◽  
S U Baglushkina ◽  
N V Efimova
Keyword(s):  
Blood Serum ◽  
Work Performance ◽  
Chemical Elements ◽  
Adult Population ◽  
Essential Elements ◽  
Anthropometric Parameters ◽  
Elemental Status ◽  
Calcium Magnesium ◽  
Biological Substrates ◽  
Cadmium And Lead

Aim. To assess the imbalance of the chemical elements in biological substrates in the adult population of Irkutsk suffering from hypertension.Methods. During the work performance, the data of 55 patients with hypertension including 40 women aged 41-66 years and 15 men aged 52-66 years living in the city of Irkutsk were investigated. During the study of the elemental status of patients with hypertension, determination of 25 elements content in the hair was performed. Analysis of the studied samples was conducted in the NGO «Center for Biotic Medicine» laboratory. 7 elements is determined by ion-selective method in the blood: K, Na, Mg, Fe, Cl, Ca, P.Results. Elemental status of patients with hypertension is characterized by a low content of essential elements - Ca (482±31.2 mg/kg), Zn (164±12 mg/kg) and Mg (154±3.3 mg/kg), significantly higher content of Na (553±156 mg/kg) in the hair; decrease in concentration of Mg (0.64±0.04 mmol/l) and Ca (2.01±0.05 mmol/l), increase in Na (149±4 mmol/l) and Cl (119.4±2.8 mmol/l) levels in blood. Increased content of chloride in blood serum, boron in the hair, potassium and lead in the hair (in men), a low content of cobalt in the hair (in men) and zinc (in women) were found; compared with men, in women lower contents of sodium in the blood serum, potassium, aluminum, cadmium and lead in the hair, a higher content of calcium, magnesium, chromium, silicon, vanadium and strontium in the hair were registered; the most pronounced correlation was observed between anthropometric parameters and the level of the chemical elements in biological samples.Conclusion. The result of assessing imbalance of the key elements in the blood is more informative than the data on selected elements, probably because the presence of any imbalance reflects either the complexity of the factor impact or the severity of the deficit or excess of one element, which caused shifts of microelement landscape as a whole.

scholarly journals Ecological and physiological assessment of the elemental status in the adult population of the Republic of Bashkortostan

2019 ◽  
Vol 95 (6) ◽  
pp. 533-538 ◽  
Author(s):  
A. V. Skalny ◽  
Elena S. Berezkina ◽  
V. A. Demidov ◽  
A. R. Grabeklis ◽  
M. G. Skalnaya
Keyword(s):  
Chemical Elements ◽  
Adult Population ◽  
The Body ◽  
Republic Of Bashkortostan ◽  
Icp Ms ◽  
Physiological Assessment ◽  
Elemental Status ◽  
The Russian Federation ◽  
The Republic ◽  
The Impact

The study of elemental status was carried out as a result of a multielement analysis of hair by ICP-MS within the framework of the Federal Program "National System of chemical and biological security of the Russian Federation, 2009-2014". This parameter is an index of the impact of the environment on the body. A total of 1,138 adult residents of the Republic of Bashkortostan (624 women and 514 men aged of25-50 years) were examined. The features of the element status of the adult population of the Republic were shown. The obtained data can be used as reference values of chemical elements in the hair of the adult population of the Republic of Bashkortostan.

scholarly journals Elemental Status of the Adult Population of Yamalo-Nenets Autonomous Okrug

2021 ◽  
pp. 248-257
Author(s):  
Lyudmila Bikbulatova ◽  
◽  
Keyword(s):  
Inductively Coupled Plasma ◽  
Dietary Habits ◽  
Indigenous Population ◽  
Chemical Elements ◽  
Adult Population ◽  
Atomic Emission ◽  
The North ◽  
Elemental Status ◽  
Simple Carbohydrates ◽  
Nenets Autonomous

Yamalo-Nenets Autonomous Okrug (YNAO), located in the northern part of the Tyumen Region, is inhabited by both indigenous and non-indigenous population. On its territory, there is a pronounced imbalance of chemical elements in the water, soil, and plants, which directly affect the elemental status of the population. Taking into account the significant differences in the nature of nutrition and lifestyle of the indigenous and newcomer population in the North, it was of interest to study the concentration of chemical elements in their hair. 173 residents of YNAO were examined: 1) 92 newcomers – 40 (43.5 %) men and 52 (56.5 %) women, who had been living in YNAO for 10 years; 2) 81 aborigines – 33 (40.7 %) men and 48 (59.3 %) women. Their mean age was 38.3 ± 9.6 years. The concentrations of Ca, Mg, Fe, Mn, Cu, Cr, Zn, Se, Cd, Pb, and Hg in the hair were determined by means of inductively coupled plasma atomic emission spectroscopy (ICP-AES) and mass spectrometry (ICP-MS) at the Centre for Biotic Medicine (Moscow). Statistically significantly higher concentrations of Ca and Mg were established against the background of a lower content of Fe and Mn in newcomers compared to the indigenous population of YNAO (p < 0.001–0.011). At the same time, both groups had almost identical content of Cu and Zn. In addition, the indigenous population showed higher concentrations of Cr (p = 0.046), Se (p < 0.001), Hg (p = 0.019), and Cd (p = 0.030) and a slight excess of Pb in their hair. The established differences in the elemental status of newcomers and aboriginal inhabitants of YNAO are associated with the geochemical characteristics of this territory, dietary habits (lower consumption of simple carbohydrates by the aborigines and a large amount of fish in their diet), as well as widespread smoking among the indigenous people.

Elemental status of the adult able-bodied population of the Republic of Buryatia

2019 ◽  
pp. 308-313
Author(s):  
Inna Yu. Tarmaeva ◽  
Anatoliy V. Skalny ◽  
Olga G. Bogdanova ◽  
Andrey R. Grabeklis ◽  
Alexandr I. Belykh
Keyword(s):  
Inductively Coupled Plasma ◽  
Chemical Elements ◽  
Federal District ◽  
Significant Degree ◽  
Electrolyte Imbalance ◽  
Scientific Development ◽  
Inductively Coupled ◽  
Elemental Status ◽  
The Republic ◽  
The Impact

Introduction.The study of the elemental status of the population of individual regions of the Russian Federation with the purpose of scientific development and implementation of measures for elimination of revealed elementosis is a promising direction for preventive medicine.The aim of the studyis to study the elemental status of the adult able-bodied population of the Republic of Buryatia, which was part of the Siberian Federal district (SFD) until 2018.Materials and methods.The analysis was performed by inductively coupled plasma mass spectrometry (ICP-MS) on the basis of the accredited laboratory of “Center of biotic medicine”. (Moscow; ISO 9001: 2008 certificate 54Q10077 from 21.05.2010). The content of chemical elements in the hair of 130 adults (102 women and 28 men) aged 25–50 years was studied. This indicator serves as an indicator in assessing the impact of the environment on the human body. Methods of nonparametric statistics were used for mathematical processing of the data.Results.For women living in the Republic of Buryatia, the maximum values of Zn, increased levels of Cu, Li, Si were revealed; for men — the maximum values of Mg, Cr, Si, increased levels of P, Li, Se, V, Pb. Minimum values were found for P, Fe, V. Elemental status indicates a significant degree of prevalence of essential trace element deficiencies and electrolyte imbalance. The obtained data can be used as reference values for the content of chemical elements in the hair of adults living in the Republic of Buryatia.Conclusions:Elemental analysis of the population of the Republic of Buryatia indicates imbalances among the adult working-age population.

Primary Teeth and Hair as Indicators of Environmental Pollution

2016 ◽  
Vol 40 (2) ◽  
pp. 152-155 ◽  
Author(s):  
TE Shishniashvili ◽  
NN Suladze ◽  
VV Margvelashvili
Keyword(s):  
Environmental Pollution ◽  
Toxic Elements ◽  
Chemical Elements ◽  
Epidemiological Survey ◽  
Essential Elements ◽  
World Health ◽  
Dental Tissues ◽  
Dental Hard Tissues ◽  
Hard Tissues ◽  
Health Organization

Objectives: To study the influence of environmental pollution on the mineralization of dental hard tissues by using biosubstrates: teeth and hair. :Study design: At the first stage epidemiological survey was conducted in polluted and less polluted areas of Tbilisi (Georgia). We studied 525 children aged 3 and 4 years. Caries prevalence and intensity was defined by the methodology of World Health Organization. At the second stage the chemical elements content was studied in hair and teeth hard tissues of 24 children by X - ray fluorescent spectroscopy method. Results: The prevalence of dental caries in the polluted region was 46%, caries intensity − 1.92 (± 2.842). In the less polluted region prevalence was 37%, caries intensity − 1.47 (± 2.571). These data are statistically reliable (p &lt; 0.05). The study of hair and tooth tissues showed that the toxic elements (Pb, Hg, Sn, Ti) content in these tissues was higher in environmentally unfavorable than in favorable conditions. Conclusion: Hair and dental tissues can be used as indicators of environmental pollution. Our survey showed that toxic elements content in dental hard tissues was higher and the level of essential elements was less in polluted than in less polluted areas of Tbilisi.

Theoretical and practical aspects in determining the current geochemical status of the Crimean peninsula and anthropogenic risk to public health

2021 ◽  
Author(s):  
Elena Evstafeva ◽  
Svetlana Tymchenko ◽  
Anna Bogdanova ◽  
Olga Zalata ◽  
Yuliia Boyarinceva ◽  
...  
Keyword(s):  
Human Body ◽  
Negative Impact ◽  
Chemical Elements ◽  
Ecological Monitoring ◽  
Crimean Peninsula ◽  
Mercury Analysis ◽  
Geographical Regions ◽  
Wide Range ◽  
Biological Substrates ◽  
Cadmium Selenium

&lt;p&gt;The implementation of basic principles of medical and ecological monitoring programs in Crimea previously reported in EGU proceedings consists of determining the content of a wide range of toxic, essential and rare earth elements in various biological substrates: soil, plants, water, human body. Biosubstrates are sampled in different locations with contrast natural and anthropogenic conditions: urbanized-rural, industrial-agricultural, natural resources. Lichens and poplar leaves are used as indicators of environmental contamination, particularly atmospheric pollution; liquid precipitation is used as an indicator showing the negative impact of air pollution on ecosystems; hair is used as an indicator of the total body intake of chemical elements. The update of databases, on some of the territories (Simferopol, Sevastopol, geographical regions with different soil characteristics, etc.) with regard to some of the elements (mercury, lead, cadmium, selenium, etc.) at this stage allowed to determine their biogeochemical status in conditions of intensive growth of anthropogenic load in recent years, and to compare it with the elemental status of the humans living in this territory. The databases for other types of territories continue to be extended, the relationship between morbidity to estimate of the environmental burden of disease for environmentally determined diseases (neurodegenerative, endocrine, respiratory, etc.) and chemical load on the territories, based on USEtox model; the functional state of target systems (nervous, immune, cardiovascular) and level of chemical elements in the human body and the overall elemental imbalance, is established. This has provided us with a degree of understanding on how the degree of population and individual health risk could be determined.&lt;/p&gt;&lt;p&gt;Mercury analysis was funded by RFBR according to the research project &amp;#8470; 18-29-24212\19 entitled &amp;#8220;Development of neutralization of mercury-containing waste without heating and the formation of wastewater&amp;#8221;, 2018&amp;#8211;2021 years; elemental composition was possible to determine due to RFBR project &amp;#8470; 18-45-920042\20 entitled &amp;#8220;Bioecological monitoring of heavy metals at board of Black Sea of Crimea&amp;#8221;, 2018&amp;#8211;2020 years. Physiological part of research was possible to accomplish due to funds by the V.I. Vernadsky Crimean Federal University (Project No VG2019/15, &amp;#1040;&amp;#1040;&amp;#1040;&amp;#1040;-&amp;#1040;20-120012090158-7).&lt;/p&gt;

scholarly journals Predictive Regression Equations of Flowmetric and Spirometric Peak Expiratory Flow in Healthy Moroccan Adults

2017 ◽  
Vol 2017 ◽  
pp. 1-7
Author(s):  
Khalid Bouti ◽  
Iliass Maouni ◽  
Jouda Benamor ◽  
Jamal Eddine Bourkadi
Keyword(s):  
Peak Flow ◽  
Adult Population ◽  
Cross Sectional Study ◽  
Regression Equations ◽  
Anthropometric Parameters ◽  
Cross Sectional ◽  
Flow Measurements ◽  
Predictive Regression ◽  
Final Sample ◽  
Main Determinants

Introduction. PEF has never been characterized among healthy Moroccan adults. The objective of this study is to describe the values of PEF among healthy Moroccan adults, to study its relationship with anthropometric parameters (gender, age, height, and weight), to compare spirometric and flowmetric PEF, to establish the prediction equations for PEF, and to study the correlation between PEF and FEV1. Methods. Cross-sectional study conducted between May and June 2016. It involved healthy nonsmoking volunteers living in Tetouan, Morocco, gathered through a mobile stand realization of spirometry and peak flow measurements. Results. Our final sample concerned 313 adults (143 men and 170 women). For both men and women, age and height were the main determinants of PEF, and a positive correlation was found between PEF and FEV1. Conclusion. Our study has established the PEF predictive equations in the Moroccan adult population. Our results allow us to conclude that the PEF can be a reliable alternative of FEV1 in centers not equipped with spirometry.

scholarly journals Influence of the genotype of Holstein breed bulls-producers on the sodium content in the blood serum of sons

2021 ◽  
pp. 125-133
Author(s):  
M. V. Strizhkova ◽  
O. I. Sebezhko ◽  
T. V. Konovalova ◽  
K. N. Narozhnykh ◽  
V. A. Andreeva ◽  
...  
Keyword(s):  
Blood Serum ◽  
Chemical Elements ◽  
Phenotypic Variability ◽  
Atomic Emission ◽  
Sodium Concentration ◽  
Sodium Content ◽  
Farm Animals ◽  
Holstein Breed ◽  
Water Feed

The study of the biological role of chemical elements in farm animals is one of the issues that scientists continue to investigate. A comprehensive study of the gene pool and phenofund of breeds and species of farm animals is being carried out in Siberia. An important issue is the search for vital markers of macronutrient accumulation, including sodium in organs and tissues of animals. The article presents data on the content of sodium in the blood serum of offspring obtained from bulls-producers of the Holstein breed. The experiment was carried out at OAO Vaganovo, Kemerovo region. The sodium concentration was determined by the atomic emission method on an ICP AES IRIS spectrometer at the V. S. Sobolev Analytical Center for Collective Use of the Institute of Geology and Mineralogy SB RAS. In the area of Holstein cattle breeding, there is no excess of LOC for heavy metals in soil, water, feed, organs and tissues of animals. The influence of the genotype of the fathers of the Holstein breed on the sodium content in the blood serum of sons was established. The sodium concentration in Fabio’s offspring was 1.9 times higher (240.4 mg/ l) than in Brio’s sons (P ˂ 0.001). By the level of sodium in the serum of offspring, bulls-producers were arranged in the following order: Brio ˂ Bonaire ˂ Malstrom ˂ Fabio in a proportion of 1: 1.3: 1.5: 1.9. The phenotypic variability of this element between the offspring of different producers differed by 3 times or more. Interbreed differentiation, the influence of the genotype of producers, differences between lines and families sign the hereditary determination of resistance and susceptibility to the accumulation of macro- and microelements in organs and tissues of animals.

Correlation of manganese in hairs with some biochemical parameters in blood serum of pigs

2021 ◽  
pp. 47-52
Author(s):  
A. V. Nazarenko ◽  
O. A. Zayko ◽  
T. V. Konovalova
Keyword(s):  
Blood Serum ◽  
Biochemical Parameters ◽  
Chemical Elements ◽  
Liver Mitochondria ◽  
Farm Animals ◽  
Industrial Complex ◽  
Irreversible Loss ◽  
Depth Study ◽  
Water Feed ◽  
Subsequent Introduction

Currently, along with an in-depth study of the gene pool and the phenotype pool of farm animals of different breeds and species in the zones of their breeding, special attention is paid to the production of environmentally friendly and safe products of the agro-industrial complex for the end consumer. Therefore, water, feed, soil, animal organs and tissues are carefully monitored for the content of chemical elements. Manganese, like magnesium and other divalent ions, is a non-specific activator of enzymes: hydrolases, kinases, decarboxylases, etc. The absolute need for Mn is confirmed by the metalloenzymes pyruvate carboxylase of the liver mitochondria and muscle oxaloacetate carboxylase. The first contains four manganese atoms and four biotin molecules and catalyzes the carboxylation of pyruvic acid to oxaloacetic acid. The removal of Mn leads to the irreversible loss of enzyme activity, which is not restored with the subsequent introduction of the endogenous metal. The purpose of the research was to establish the correlations of the accumulation of manganese in the hairs with some biochemical parameters in the blood of pigs of Kemerovskaya breed. During the work the correlations of manganese in the hairs with some biochemical parameters of blood serum of pigs have been studied. When comparing the obtained data with the studies of other scientists, all the correlations were described except for the content of manganese in the hairs with serum chlorides (r=–0,43), since this correlation was not confirmed by the data of the scientific literature. A positive correlation has been established between the level of Mn with cholesterol and Mg at the level of 0,542 and 0,417, respectively. The change in the magnitude and direction of the correlation between the concentration of Mn in the hairs and the biochemical composition of the blood can be caused by some animal diseases.

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