scholarly journals Regional ozonotherapy of vertebrogenic pain syndromes in lumbosacral localizations

2000 ◽  
Vol XXXII (1-2) ◽  
pp. 47-51
Author(s):  
S. A. Kotov
Keyword(s):  
Muscle Activity ◽  
Trigger Points ◽  
Main Group ◽  
Biologically Active ◽  
Reflex Activity ◽  
Oxygen Mixture ◽  
Control Group ◽  
Pain Syndromes ◽  
Temperature Asymmetry

In 47 patients а traditional analgetic therapy has been added to injection of ozon-oxygen mixture into paravertebral, biologically active, "trigger" points, and also with small autohemotherapy of ozonized blood. In the main group more reliable rates of pain regress were registered, as well as less percentage of patients resistant to the therapy as compared with ones in the control group. Levelling of muscular-tonic and neurodystrophic phenomena was more expressed at reflex vertebral and extravertebral syndromes, and it was accompanied by positive shifts concerning bioelectrical muscle activity, reflex activity normalization of -motorneurons, decrease of temperature asymmetry of legs.

Antioxidant status of blood in patients with vibration disease

2019 ◽  
pp. 978-982 ◽  
Author(s):  
N. N. Malyutina ◽  
A. F. Bolotova ◽  
R. B. Eremeev ◽  
A. Zh. Gilmanov ◽  
D. Yu. Sosnin
Keyword(s):  
Antioxidant Activity ◽  
Blood Serum ◽  
Antioxidant Status ◽  
Total Antioxidant Status ◽  
Main Group ◽  
Biologically Active ◽  
Antioxidant Systems ◽  
Control Group ◽  
Vibration Disease ◽  
Total Antioxidant

Introduction. The overwhelming number of publications contains only data on the content of individual antioxidants, but not on the overall antioxidant activity of the blood in patients with vibration disease.The aim of the study was to determine the total antioxidant activity of blood serum in patients with vibration disease.Materials and methods. Th e main group consisted of 30 people diagnosed with “Vibration disease” of 1 degree (n=21) and 2 degrees (n=9). Th e control group consisted of 30 clinically healthy men, comparable in age with the main group (p=0.66). Th e total activity of antioxidant systems of blood plasma was evaluated photometrically using the test system “Total antioxidant status-Novo” (“Vector-best”, Russia).Results. The indicator of the total antioxidant status (TAS) was 1,038±0.232 mmol/l in the examined main group, against 1,456±0.225 mmol/l in the examined control group (p<0.000001). Th e coefficient of variation (CV) in patients with vibration disease was 22.35%, 1.45 times higher than in the control group (15.45%). In the main group there was a positive correlation between age and TAS (R=0.525), in the control group there was no such relationship (R=0.095). Th e degree of decrease depended on the severity of vibration disease.Conclusions. 1. The development of vibration disease is accompanied by a decrease in the antioxidant status of blood serum. 2. Th e degree of decrease in the antioxidant status of blood serum correlates with the severity of vibration disease. 3. Reduction of TAS can serve as a pathogenetic justification of the need to include drugs and/or biologically active additives with antioxidant activity in therapy

scholarly journals Clinical approbation of biologically active supplement in patients with vegetovascular dystonia

2018 ◽  
Vol 35 (6) ◽  
pp. 43-48
Author(s):  
A. A. Vekovtsev ◽  
G. A. Podzorova ◽  
V. M. Poznyakovsky
Keyword(s):  
Blood Flow ◽  
Nervous System ◽  
Cellular Membrane ◽  
Main Group ◽  
Biologically Active ◽  
Control Group ◽  
Tablet Form ◽  
Complex Therapy ◽  
Active Supplement ◽  
Positive Effect

Aim. To study the possibility of using and estimate the efficiency of a new tablet form of biologically active supplement in patients with vegetovascular dystonia syndrome. Materials and methods. One hundred patients with vegetovascular dystonia syndrome, including 50 patients of the main group and 50 patients of the control group were examined. There is presented the composition of prescription formula of biologically active supplement, based on participation of its components in the correction of disturbed metabolic processes of the nervous system. Results. Additional application of biologically active supplement in combination with drug significantly improves cerebral blood flow, decreases blood viscosity and risk of cellular membrane impairment, normalizes arterial pressure, elevates initiative and attention, reduces headache in patients of the main group with vegetovascular dystonia syndrome. Conclusions. Use of biologically active supplement has a positive effect in complex therapy of patients with vegetovascular dystonia syndrome.

The effect of laser phoresis of biologically active substances on microcirculation in paravertebral muscles in the radicular syndrome of the lumbosacral spine

2021 ◽  
pp. 72-76
Author(s):  
Nataliya Borisovna Korchazhkina ◽  
Ruslan Vladimirovich Kupeev
Keyword(s):  
Therapeutic Effect ◽  
Pathological Process ◽  
Main Group ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Control Group ◽  
Lumbosacral Spine ◽  
Paravertebral Muscles ◽  
Radicular Syndrome ◽  
Active Substances

In the case of radicular syndrome in patients with dorsopathy, degenerative dystrophic changes, which contribute to the creation of additional mechanisms of pain impulse and chronization of the pathological process, are diagnosed in the deep muscles. The study included 40 patients with dorsopathy of the lumbosacral spine and radicular syndrome, with the average age of 45,3±1,5years, who were divided into 2 groups comparable in age and clinical and functional characteristics: the main group of 20 patients who were treated with laser phoresis of biologically active substances and the control group of 20 patients who received standard pharmacotherapy. As a result of the study, a significantly more pronounced improvement in the state of microcirculation in the paravertebral muscles when using phytoextracts laser phoresis was proved, which was confirmed by radiothermometry and transcutaneous oximetry. The analysis of radiothermometry and oximetry parameters obtained 3 months after the end of the course showed the stability of the therapeutic effect in 96% of patients in the main group, while in the control group, 50% of patients showed a regression of the effect obtained as a result of treatment. In longer terms, the therapeutic effect in 90% of patients of the main group was maintained for 9–12 months of follow-up, while in the control group — no more than 3–4 months.

scholarly journals Prediction and prevention of postoperative intra-abdominal adhesive complications in children

2021 ◽  
Vol 1 (1) ◽  
pp. 127-132
Author(s):  
Sh. A. Yusupov ◽  
U. T. Suvonkulov ◽  
Sh. Sh. Yusupov ◽  
V. U. Sataev
Keyword(s):  
Abdominal Cavity ◽  
Adhesion Formation ◽  
Experimental Studies ◽  
Main Group ◽  
Oxygen Mixture ◽  
Control Group ◽  
Acetylation Phenotype ◽  
Prediction And Prevention ◽  
Synthetic Function ◽  
Adhesive Intestinal Obstruction

The aim of this work was to study the morphology of adhesion formation under the influence of ozone in the experiment, as well as the development of prediction criteria and methods for correcting increased adhesion in children.Materials and methods. Experimental studies were carried out on 36 rabbits «Shinshilla» with a body weight of 0.7–1.2 kg., of which 12 animals were included in the control group, which did not carry out ozonation of the abdominal cavity. The main group consisted of 24 rabbits, which were divided into two subgroups (12 animals in each subgroup), which ozonized the abdominal cavity with an ozone-oxygen mixture. In order to study the prognostic value of the acetylation phenotype in the formation of intraperitoneal adhesions, 67 children with symptoms of adhesive intestinal obstruction were examined.Results. The results of experimental studies showed that in animals of the control group there was the formation of massive adhesions. The basis of adhesions is connective tissue with a significant number of fibroblasts, blood vessels and collagen fibers. In animals of the main group, sharp inhibition of adhesion formation, a delay in the differentiation of fibroblasts and inhibition of their synthetic function were revealed. Acetylation phenotype was determined in 58 patients with appendicular peritonitis. 30 (51%) children turned out to be slow acetylators, and in 28 (49%) patients the phenotype of fast acetylation was established. The results of the study allowed us to isolate fast acetylators as a risk group for excessive adhesion formation and timely start therapeutic and preventive measures.

scholarly journals CLINICAL AND IMMUNOLOGICAL FEATURES OF INFLAMMATORY DISEASES OF THE PELVIS AND GENITAL ORGANS IN HIV-INFECTED WOMEN

2021 ◽  
Vol 58 (2) ◽  
pp. 4996-5001
Author(s):  
Olimova N.I., Ikhtiyarova G.A.
Keyword(s):  
Hiv Infection ◽  
Inflammatory Diseases ◽  
Main Group ◽  
Biologically Active ◽  
Enzyme Linked Immunosorbent Assay ◽  
Control Group ◽  
Inflammatory Processes ◽  
The Russian Federation ◽  
Interferon System ◽  
Effective Remedy

The aim of the study is to study the cytokine profile in HIV-infected women with acute vaginitis against the background of complex conservative treatment. Materials and methods of research 55 women aged from 25 to 55 years with acute vaginitis were under our supervision. All women were surveyed for the period from 2018 to 2020, of which 35 women with HIV infection, which constitutes the main group, and 20 women without HIV infection, which constitutes the control group. In all female patients, cytokines (to determine inflammatory processes) (IFNγ, IL-17) were determined in the peripheral blood serum. IFNγ, IL-17 were determined by enzyme-linked immunosorbent assay using test systems "Vector-Best" of the Russian Federation. Results and discussion: the ratio of IFNγ / IL-17 (pro-inflammatory / anti-inflammatory cytokines or Th1 / Th2) in HIV-uninfected women was 2.2. In the presence of a pronounced inflammatory process, that is, in HIV-uninfected women, this indicator was 0.96. After carrying out immunocorrective treatment using Immun-5 (The drug is a balanced mixture of natural biologically active substances, the action of which is aimed at activating the body's immune system. The drug increases the body's resistance in inflammatory diseases. An effective remedy for HIV / AIDS, hepatitis and tuberculosis. 1 capsule 2 times a day for 60 days The drug manifests its effects primarily through the effect on the endogenous interferon system and on the expression of cytokines functionally coupled with interferons - IL-2, IL-4, IL-6, IL-10 and IL-17). In the examined HIV-infected women with nonspecific vaginitis, IFNγ approached the control values, the content of IL-17, and after treatment did not normalize, remaining 5.5 times higher than in HIV-uninfected women in the control group, the ratio of IFNγ / IL-17, in HIV-infected women of the main group, after treatment this indicator decreased to 0.42. Conclusion: The improvement in the clinical condition of HIV-infected women, along with the suppression of the level of the pro-inflammatory cytokine IFNγ, was accompanied by the disappearance of signs of inflammation of the genitalia, an improvement in the general condition of HIV-infected women.

Osteopathy as a method of correction and prevention of the formation of somatic dysfunctions of the musculoskeletal system in office workers

2021 ◽  
pp. 54-65
Author(s):  
I. A. Aptekar ◽  
E. V. Abramova
Keyword(s):  
Musculoskeletal System ◽  
Randomized Study ◽  
Life Quality ◽  
Main Group ◽  
Office Workers ◽  
Control Group ◽  
Pain Syndromes ◽  
Urgent Task ◽  
And Control ◽  
Local Levels

Introduction. According to Russian and foreign studies, the frequency of musculoskeletal system pathology continues to grow. To improve the life quality and reduce the level of the musculoskeletal system diseases, an urgent task is to increase the volume of available non-drug methods of prophylaxis.The aim of the research was to develop measures to prevent the formation of somatic dysfunctions of the musculoskeletal system and their relapses in office workers using osteopathic correction.Materials and methods. In the period from 2016 to 2020, a prospective controlled randomized study was carried out on the basis of the ANO TIMM. The work is based on the results of osteopathic care in combination with a controlled change in the ergonomics of the workplace after the correction of somatic dysfunctions of the musculoskeletal system in office workers. The study involved 426 people who were divided into two comparable groups: the main and control groups of 212 and 214 people, respectively. All patients underwent osteopathic diagnostics before the start of the treatment, during therapy, and at its completion in accordance with the approved clinical guidelines. Patients of both groups received osteopathic care provided in accordance with the developed algorithm. The patients of the main group underwent correction of their workplaces ergonomics.Results. The study showed that office workers are characterized by the presence of somatic dysfunctions at the regional and local levels. Somatic dysfunctions of the spine, pelvis, abdominal and pelvic diaphragms were most often observed. As a result of osteopathic correction in combination with a change in the ergonomics of the workplace in patients of the main group, the frequency of recurrences of the somatic dysfunctions formation decreased significantly (p<0,05) compared with patients in the control group. It also was accompanied by a significant decrease in the pain syndromes recurrence.Conclusion. The use of osteopathic correction in combination with the workplace ergonomics change effectively contributes to the prevention of the formation of the musculoskeletal system somatic dysfunctions and their recurrence in office workers.

scholarly journals The experience of polyradiomodification with the use of ozone-oxygen mixture in complex treatment of the squamous cell cervical cancer

2012 ◽  
Vol 93 (6) ◽  
pp. 879-883
Author(s):  
A V Panov ◽  
M V Burmistrov ◽  
I S Raginov ◽  
A V Berdnikov ◽  
E Y Mindubaev ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Side Effects ◽  
Squamous Cell ◽  
Tumor Tissue ◽  
Main Group ◽  
Post Treatment ◽  
Oxygen Mixture ◽  
Control Group ◽  
Complex Treatment ◽  
Complications Rate

Aim. To improve the results of complex treatment of stage IIb squamous cell cervical cancer. Methods. 53 patients with stage IIb squamous cell cervical cancer were included. All patients underwent combined radiotherapy (teletherapy plus brachytherapy) and were treated with intravenous cisplatin followed by hysterectomy by Wertheim. As a pre-surgical treatment 31 patients (main group) underwent rectal insufflations of ozone-oxygen mixture as a radio modifier. The original method and machine pulse oxymetry of the tumor tissue oxygenation were used. 22 (41.5%) who were included in the control group underwent combined chemoradiotherapy without use of ozone-oxygen mixture. A comparative analysis of tumor tissue post-treatment pathomorphism, chemoradiotherapy side effects rate and post-surgical complications rate was performed in both of the groups. Results. All complications were transient and could be easily managed symptomatically. Hence, there was a tendency of side effects rate and complications rate decrease in the main group. Cystitis as a complication of radiotherapy was observed in 1 (3%) patient of the main group and in 2 (9%) of the control group, proctitis - in 5 (16%) patients of the main group and in 4 (18%) patients of the control group. Leukocytopenia (I-II degree) as the most frequent hematological chemotherapy complication was registered in 7 (22%) patients of the main group and in 17 (72.2%) patients of the control group. Flu-like syndrome was observed in 1 (3%) patient of the main group and in 2 (9%) patients of the control group. There were no grade III and IV toxicity events. Proposed pre-surgical chemoradiotherapy of the localized stage IIb cervical cancer with an ozone-oxygen mixture as a radio modifier was characterized by high (grade IV) tumor tissue post-treatment pathomorphism level reaching 44.8%. Conclusion. The use of rectal insufflations of ozone-oxygen mixture allowed to decrease the rate of chemotherapy and radiotherapy complications, but the difference was not statistically significant. To increase the power of the study, more subjects are needed to be recruited with a longer follow-up.

Clinical efficacy of osteopathic correction in the complex treatment of patients with unoperated open-angle glaucoma

2020 ◽  
pp. 97-105
Author(s):  
E. N. Simakova ◽  
O. V. Stenkova
Keyword(s):  
Intraocular Pressure ◽  
Drug Therapy ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Randomized Study ◽  
Main Group ◽  
Control Group ◽  
Open Angle ◽  
Complex Treatment ◽  
Hypotensive Drug

Introduction. Glaucoma is one of the most significant eye diseases. It is often diagnosed, not always amenable to therapy, and can lead to a complete loss of visual functions. In recent years, the method of osteopathic correction has become widespread as one of the effective methods of treatment and rehabilitation of patients with pathologies of various body systems. In the pathogenesis of glaucoma, it is customary to distinguish a dystrophic concept, which considers primary open-angle glaucoma as a result of dystrophic changes in the connective tissue, as well as in the endothelial lining of the trabeculae and Schlemm′s canal, especially destructive changes in mitochondria and the alteration of their functional activity. A vascular concept is also distinguished. According to this concept, the central link in the pathogenesis of glaucoma is circulatory disorder in the ciliary vessels, ocular artery, and major vessels of the head and neck, it can be assumed that osteopathic correction in the treatment of patients with open-angle glaucoma will be pathogenetically substantiated and will have a positive effect on intraocular pressure and trophicity of the optic nerve. The goal of research — to study the influence of in osteopathic correction on the nature of unoperated glaucoma (stage IIA) and to substantiate the possibility of using osteopathic correction in the complex treatment of patients with this pathology.Materials and methods. A prospective controlled randomized study was conducted at 52 city polyclinics, branch 3, Moscow, from January 2018 to January 2019. 40 patients (70 eyes) aged 50 to 75 years with primary open-angle glaucoma IIA stage were examined. At this stage of the disease, patients most often seek medical care and the issue of conservative management is primarily considered. All patients were divided into two groups of 20 people: the main group and the control group. The treatment in the main group included hypotensive drug therapy and osteopathic correction. Patients of the control group received only drug therapy. All patients underwent ophthalmic (visometry, tonometry, perimetry) and osteopathic examination twice: before the treatment and after 3 months.Results. For patients with primary open-angle IIA non-operated glaucoma, regional (most often regions of the head, neck, dura mater) and local (abdominal diaphragm, iliac bones, hip and knee joints) somatic dysfunctions were the most typical. In the main group a statistically significant decrease in the frequency and severity of dysfunctions at all levels was stated. Also, in patients receiving osteopathic correction, a significant decrease in the level of intraocular pressure and perimetric indices was noted. In patients of the control group, no reliable changes in these indicators were obtained.Conclusion. The results obtained indicate that osteopathic correction is clinically effective in the complex treatment of patients with primary open-angle II A glaucoma.

Experience of using time-lapse microscopy in IVF and ICSI programs

2020 ◽  
pp. 47-50
Author(s):  
N. V. Saraeva ◽  
N. V. Spiridonova ◽  
M. T. Tugushev ◽  
O. V. Shurygina ◽  
A. I. Sinitsyna
Keyword(s):  
Pregnancy Rate ◽  
Embryo Transfer ◽  
Selection Procedure ◽  
Time Lapse ◽  
Single Embryo Transfer ◽  
Main Group ◽  
Clinical Pregnancy ◽  
Control Group ◽  
Time Lapse Microscopy

In order to increase the pregnancy rate in the assisted reproductive technology, the selection of one embryo with the highest implantation potential it is very important. Time-lapse microscopy (TLM) is a tool for selecting quality embryos for transfer. This study aimed to assess the benefits of single-embryo transfer of autologous oocytes performed on day 5 of embryo incubation in a TLM-equipped system in IVF and ICSI programs. Single-embryo transfer following incubation in a TLM-equipped incubator was performed in 282 patients, who formed the main group; the control group consisted of 461 patients undergoing single-embryo transfer following a traditional culture and embryo selection procedure. We assessed the quality of transferred embryos, the rates of clinical pregnancy and delivery. The groups did not differ in the ratio of IVF and ICSI cycles, average age, and infertility factor. The proportion of excellent quality embryos for transfer was 77.0% in the main group and 65.1% in the control group (p = 0.001). In the subgroup with receiving eight and less oocytes we noted the tendency of receiving more quality embryos in the main group (р = 0.052). In the subgroup of nine and more oocytes the quality of the transferred embryos did not differ between two groups. The clinical pregnancy rate was 60.2% in the main group and 52.9% in the control group (p = 0.057). The delivery rate was 45.0% in the main group and 39.9% in the control group (p > 0.050).

The effect of probiotics on the level of immunoglobulin A in women with violation of the biocenosis of the vagina

2017 ◽  
pp. 85-88
Author(s):  
O.I. Ostapenko ◽  
◽  
V.P. Kvashenko ◽  
I.K. Akimova ◽  
I.N. Nosova ◽  
...  
Keyword(s):  
Immunoglobulin A ◽  
Lactobacillus Rhamnosus ◽  
Test System ◽  
Main Group ◽  
Reproductive Age ◽  
Local Action ◽  
Serum Immunoglobulin ◽  
Control Group ◽  
Local Immunity ◽  
Serum Iga

The objective: the study of immunomodulatory effects of a probiotic, which contains lyophilized Lactobacillus (Lactobacillus rhamnosus) – 13 mg (2,0ґ109 CFU) and lyophilized bifidobacteria (Bifidobacterium lactis) – 4 mg (2,0ґ109 CFU) the level of serum immunoglobulin IgA as a marker of local immunity in the plasma of women of reproductive age with the violation of the biocenosis of the vagina. Patients and methods. The study involved 86 patients of reproductive age with the violation of the vaginal biocenosis, which were divided into two groups according to received treatment. A survey was conducted for all patients in both groups: determine the level of serum IgA, measuring pH of vaginal environment and the quantification of lactobacilli and pathogenic flora with the help of test-system «Florotsenoz» before treatment and in 6 weeks after treatment. The state of vaginal microbiocenosis in both groups before treatment was homogeneous. Patients in both groups as therapy at the first stage of treatment received, if necessary antimicrobial therapy depending on the selected flora. In the second stage (restoration of microflora) patient of the main group received systemic probiotic combined with a complex prebiotic local action, patients in the control group, the probiotic localy in the form of the vaginal candles or tablets. Results. The research stated the increasing level of serum IgA in blood plasma of patients of the main group compared to control group at 20%, normalizing the pH of the vaginal environment in the main group in 94% of cases, which indicates an increase of immunity in mucosal. Conclusion. The inclusion of the systemic probiotic in the scheme of treatment of disorders of biocenosis of the vagina system enhances the increasing of immunity of the mucous membranes, and the vaginal tablets prebiotic of local action restores the own normal microflora of the vagina. Key words: serum immunoglobulin A, local immunity, vaginal dysbiosis, probiotics, prebiotics, vaginal microbiocenosis, the pH of the vaginal environment.

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