scholarly journals Features of primary disability due to eye diseases in the Krasnodar region

2013 ◽  
Vol 6 (2) ◽  
pp. 16-19
Author(s):  
Anastasiya Sergeevna Apostolova
Keyword(s):  
Statistical Study ◽  
Group Analysis ◽  
Disabled Persons ◽  
Retirement Age ◽  
Entire Observation Period ◽  
Group I ◽  
Primary Disability ◽  
People First ◽  
First Time ◽  
Observation Period

A continuous statistical study of primary disability dynamics in ophthalmic patients during 2006–2011, according to the data from the branch # 7. For the entire observation period, a decrease in number of people first-time recognized as disabled was found. The nosologic structure of primary disability is shown, with glaucoma occupying the first place for the entire observation period, and myopia the second one during the last 5 years. Decreasing disability due to lens changes was found, from the second rank to the 6th one. An increase in primary disability due to AMD was recognized, moving AMD from the 10th place to the 3rd. A group analysis of patients, in whom glaucoma was a disabling condition, was performed. In 88–93% of cases, these persons were of retirement age. Higher prevalence of disability was noted among urban population. Among rural population in comparison with urban one, there were more group I and less group II disabled persons.

scholarly journals The Analysis of Primary Disability Due to Malignant Neoplasms among Persons of Retirement Age in Moscow in 2012–2018

2020 ◽  
pp. 4-7
Author(s):  
YA Kovrizhnykh ◽  
NS Zapariy ◽  
MV Kovrizhnykh
Keyword(s):  
Statistical Significance ◽  
Federal District ◽  
The Elderly ◽  
Specific Weight ◽  
Malignant Neoplasms ◽  
Retirement Age ◽  
Expert Evaluation ◽  
Primary Disability ◽  
People First ◽  
Analytical System

Our objective was to study indicators and structure of primary disability due to malignant neoplasms among persons of retirement age in 2012–2018 and to determine the patterns of its formation. Material and methods: The continuous research was based on data of the Unified Automated Vertically Integrated Information and Analytical System for Medical and Social Expert Evaluation for 2012–2018, “7-Sobes” statistical reports, and statistical compilations of the Federal Bureau of Medical and Social Expert Evaluation of the Russian Ministry of Labor. The methods applied included data copying, descriptive statistics, analytical and comparative analysis, calculation of the mean error and statistical significance. Results: The study of primary disability rates due to malignant neoplasms among people of retirement age in Moscow in 2012–2018 showed that the number of people first recognized as disabled increased up to 13,827 people (+77.8%). This finding could be related to the increase in the number of people of retirement age by 21.2% in Moscow during the period under review. As for the severity of disability, then people with grade II disability prevailed but their specific weight and the rate of primary disability tended to decrease. At the same time, we observed an increase in the specific weight of disabled people of Grade III. The five-year survival rate of cancer patients increased by 30% from 51% to 65.4% in 2011–2018, and so did the proportion of cases detected in early stages. Conclusions: Disability caused by malignant neoplasms among the elderly in Moscow in 2012–2018 was characterized by an increase in the number of people first recognized as disabled from 7,782 to 13,827 people (+77.8%) and an increase in their specific weight from 59.4% to 61.3% (60.6% on the average) in the structure of those first recognized as disabled from these causes. An increase in the rate of primary disability from 27.7 ± 0.5 to 40.6 ± 1.3, averaging 30.2 ± 0.5, was also observed but it remained lower than that in the Central Federal District and the Russian Federation as a whole.

MAJOR TRENDS IN INCIDENCE AND PRIMARY DISABILITY DUE TO MALIGNANT NEOPLASMS AMONG ADULT POPULATION OF THE TOMSK REGION FROM 2015 TO 2019

2020 ◽  
Vol 66 (6) ◽  
pp. 2-2
Author(s):  
V.A. Perminov ◽  
◽  
A.V. Nagaytsev ◽  
Keyword(s):  
Adult Population ◽  
Federal District ◽  
Malignant Neoplasms ◽  
Retirement Age ◽  
Siberian Federal District ◽  
Initial Examination ◽  
Group I ◽  
Tomsk Region ◽  
The Disabled ◽  
Primary Disability

The article presents results of the analysis of indicators of cancer incidence and primary disability due to malignant neoplasms among adult population of the Tomsk region in dynamics for 2015 - 2019, which indicate an upward trend (by 30.7%) exceeding the average indicators for the Russian Federation and the Siberian Federal District. Increased prevalence of malignant neoplasms among adult population of the Tomsk region over the period under study is due to better detection of malignant neoplasms (a 8.7% increase), as well as implementation of the new and improved methods of special anticancer treatment aimed at complete recovery and increased life expectancy of cancer patients. Malignant neoplasms were more often detected among urban population aged 65 and over (64.8%). The incidence rate of malignant neoplasms in the region progressed from 433.8 to 626.1 per 10 000 population due to increased detection of malignant neoplasms at the early stages (by 2.9%). The rate of advanced cases over the study period decreased by 1.5%. Since 2014, malignant neoplasms have been taking the lead in the structure of adults recognized as disabled for the first time. Indicators of primary disability in the adult population for the period 2015 - 2018 decreased, followed by the increase in 2019, however, the disability rate in all adult age groups remained below the similar indicators in Russia and the Siberian Federal District. Women, persons of the retirement age, and urban dwellers prevailed in this contingent of the disabled. The share of people of working age decreased from 38.4% to 35.2%. The share of people of the retirement age increased from 61.6% to 64.8%, respectively. Group II disability was the most often established, in dynamics, the share of the disabled with groups II and III decreased. There was a significant increase from 20.4% to 31.9% in the share of citizens who, during the initial examination, were established as group I. The main localizations of malignant neoplasms resulting in disability in 2015 - 2017 included mammary gland, larynx, trachea, bronchi and lungs, and female genital organs; and stomach and large intestine - in 2018 - 2019. The share of malignant neoplasms with multiple localizations increased from 1.8% to 5.2%.

scholarly journals Features of Primary Ocular Disability in the Krasnodar Region in 2016–2018

2021 ◽  
Vol 18 (4) ◽  
pp. 955-961
Author(s):  
A. S. Apostolova ◽  
A. V. Malyshev ◽  
A. A. Bashko ◽  
A. A. Sergienko ◽  
E. V. Kudryavceva
Keyword(s):  
Adult Population ◽  
Progressive Increase ◽  
Eye Diseases ◽  
Retirement Age ◽  
Blind And Visually Impaired ◽  
Primary Disability ◽  
Working Age ◽  
Krasnodar Region ◽  
Group 2 ◽  
First Time

Purpose: to study the state and dynamics of changes in primary ocular disability in the period 2016–2018 by nosological forms. A complete retrospective study was made based on the data of the MSE (medical and social expertise) Bureau’s reporting documents. The following indicators of primary disability (per 10 thousand population) were registered from 2016 till 2018: among the adult population (18 years and older) 69,0–70,7–68,6 respectively; among the able-bodied population 42,8–44,1–41,1 respectively; among the population of retirement age — 125,1–126,4–124,6 accordingly. In the structure of primary disability of the adult population by severity for the period 2016–2018, the dynamics recorded an increase in the proportion of 1 group and 3 group with a decrease in the share of disability of 2 group. In the nosological structure of primary disability of the adult population in 2016–2017–2018, eye diseases account for 3 %, 3 % and 3.2 %, respectively, of all first recognized as disabled. There has been an increase in first-time applicants to the MSE Bureau. In the nosological structure of primary disability, the percentage of glaucoma patients over the past period is 47–33–32.5 % of the total number of primary disability for eye diseases, which determines the 1st rank. There is a progressive increase in the number of people with disabilities due to glaucoma of group 1 and group 2 throughout the study period. In the nosological structure of primary disability for 2016–2018 the percentage of patients with retinal diseases is 25–23–23.8 % of the total number of primary disability for eye diseases, which corresponds to the 2nd rank. There is a progressive increase in the number of disabled people in group 2. A low proportion of persons of working age in the structure of primary ocular disability was noted. A consistently high share of primary disability and a progressive increase in severe disability combined with an increase in persons of retirement age in the Krasnodar region forms an unfavorable forecast for an increase in the number of blind and visually impaired residents of the region.

scholarly journals Diseases of digestive organs as a cause of disability in Rostov region

2019 ◽  
Vol 22 (1) ◽  
pp. 19-24
Author(s):  
A. Y. Paikov ◽  
Natalya S. Zapariy ◽  
Marina A. Urusova ◽  
Natalya A. Andreeva ◽  
Vadim N. Dmitriev ◽  
...  
Keyword(s):  
Russian Federation ◽  
Adult Population ◽  
Federal District ◽  
Disabled Persons ◽  
Persons With Disabilities ◽  
Digestive Organs ◽  
Rostov Region ◽  
Group I ◽  
Primary Disability ◽  
The Russian Federation

The analysis presented in the article of the primary disability of the adult population due to diseases of digestive organs in the Rostov region for 20122018 was characterized by an increase in the number of persons recognized as disabled for the first time as in the Southern Federal District and the Russian Federation. In the structure of the first recognized disabled persons, their share was higher than in the Southern Federal District, but lower than in the Russian Federation. The level of primary disability for 20122018 was lower than in the Southern Federal District and the Russian Federation. The age structure was dominated by persons with disabilities of working age (women aged 4554; men 4559 years old) as well as in the Southern Federal and Russian Federation. The severity of disability was dominated by group II persons with disabilities, with a tendency to increase their specific weight, as in the Southern Federal District and the Russian Federation; Group III persons with disabilities ranked second, with a tendency to reduce their share and level. There has been an increase in the proportion of group I disabled persons.

G4120, an Arg-Gly-Asp Containing Pentapeptide, Enhances Arterial Eversion Graft Recanalization with Recombinant Tissue-Type Plasminogen Activator in Dogs

1992 ◽  
Vol 67 (06) ◽  
pp. 686-691 ◽  
Author(s):  
Hua Rong Lu ◽  
Herman K Gold ◽  
Zaomin Wu ◽  
Tsunehiro Yasuda ◽  
Patrick Pauwels ◽  
...  
Keyword(s):  
Plasminogen Activator ◽  
Arterial Occlusion ◽  
Tissue Type ◽  
Clot Lysis ◽  
Arterial Graft ◽  
Tissue Type Plasminogen Activator ◽  
Group I ◽  
Type Plasminogen Activator ◽  
Platelet Receptor ◽  
Observation Period

SummaryThe effects of G4120, a cyclic Arg-Gly-Asp (RGD) containing peptide which inhibits fibrinogen binding to the platelet receptor GPIIb/IIIa, on thrombolysis with recombinant tissue-type plasminogen activator (rt-PA) were investigated in a combined arterial and venous thrombosis model in heparinized dogs. The arterial thrombus model consisted of a 3 cm everted (inside-out) carotid arterial segment inserted into a transsected femoral artery which occludes within 30 min with platelet-rich material and which is resistant to recanalization with 0.5 mg/kg rt-PA. The venous thrombus was a 125I-fibrin labeled whole blood clot produced in the contralateral femoral vein.In 5 dogs given an intravenous bolus of 0.05 mg/kg G4120 followed by a continuous infusion of 0.05 mg/kg per hour for 3 h (group I), arterial occlusion persisted throughout a 4 h observation period and was still present at 24 h in all dogs; the extent of venous clot lysis after 120 min was 27 ± 7%. In 5 dogs given the same infusion of G4120 in combination with 0.5 mg/kg rt-PA over 60 min, recanalization of the arterial graft occurred in all dogs, within 13 ± 2 min and persisted throughout the observation period of 4 h (p = 0.01 versus G4120 or rt-PA alone); at 24 h, however, all grafts were occluded. Venous clot lysis in this group was 75 ± 8% (p = 0.002 versus G4120 alone andp NS versus rt-PA alone). Pathologic analysis revealed platelet-rich or mixed thrombus with platelet-rich and erythrocyte-rich zones. The last 6 dogs were given a reduced dose of G4120 consisting either of a 0.05 mg/kg bolus followed by an infusion of 0.05 mg/kg over 1 h in 3 dogs (group III) or of a single 0.05 mg/kg bolus in 3 dogs (group IV), both given in combination with 0.5 mg/kg rt-PA infused over 60 min. These protocols produced recanalization within 15 ± 2 and 34 ± 8 min, respectively, which was maintained throughout the 4 h observation period. Venous lysis in these groups was 63 ± 4 and 97 ± 1% respectively. Bleeding times prolonged from 1 to 2 min to >30 min with G4120, but returned towards baseline within 2 h after the end of the infusion. Platelet aggregation with ADP was completely inhibited with G4120 but partially recovered within 1 h after the end of the infusion. No fibrinogen breakdown was observed in association with the rt-PA infusion.Thus, G4120, a synthetic GPIIb/IIIa receptor antagonist, enhances and accelerates lysis of platelet-rich arterial thrombosis with rt-PA and prevents reocclusion during and within 3 h after the infusion. It may be useful for the conjunctive use with thrombolytic agents in patients with arterial thromboembolic disease.

Studies of rootstocks for stone fruit breeds (sweet cherry) in the condition of Hissar valley in Tajikistan

2019 ◽  
Vol 1 (4) ◽  
pp. 28-34
Author(s):  
Rahima I. Ismoilova ◽  
Sodzhida D. Umarova
Keyword(s):  
Sweet Cherry ◽  
Sour Cherry ◽  
High Specificity ◽  
Stone Fruit ◽  
Wild Cherry ◽  
Phenological Observation ◽  
Entire Observation Period ◽  
The Individual ◽  
Leaf System ◽  
Observation Period

This paper is about studying the rootstocks for stone fruit breeds (sweet cherry) in condition of Hissar valley in Tajikistan. Each type of rootstock has its own biological characteristics and imposes specific requirements for growing and development, both during reproduction in the mother plantation and during the growth of trees. For example, the root system in sour cherry is more superficial that of wild sweet cherry. Therefore, the care of trees grafted on sour cherry and wild cherry and of mother plantation bushes of these rootstocks cannot be same. Besides, there are very significant differences among the individual groups of rootstocks. Wild cherry, Mahaleb cherry and Lubskaya cherry are used as rootstocks in the conditions of the Hissar Valley in Tajikistan. High specificity of sweet cherry cultivar varieties depends on the rootstocks. Phenological observation were carried out in our experiments during years 2013-2018 in order to study their winter resistance, yield capacity and fruit quality. The same care for root and grafted plants was carried out during the entire observation period. At the same time a certain ratio between the leaf system of the rootstock and the graft was maintained by trimming the crown. As a result of the evolution and selection, we have identified the wild cherry forms which are distinguished by the highest yields. The most valuable cultivar varieties are Napoleon cherry and Bagration cherry. Compotes made of these varieties have received high evaluation in tasting.

scholarly journals Characterization of Fusarium oxysporum Isolates Obtained from Cucumber in China by Pathogenicity, VCG, and RAPD

Plant Disease ◽  
2004 ◽  
Vol 88 (6) ◽  
pp. 645-649 ◽  
Author(s):  
D. J. Vakalounakis ◽  
Z. Wang ◽  
G. A. Fragkiadakis ◽  
G. N. Skaracis ◽  
D.-B. Li
Keyword(s):  
Fusarium Oxysporum ◽  
Random Amplified Polymorphic Dna ◽  
Vegetative Compatibility ◽  
Stem Rot ◽  
Chinese Isolate ◽  
Vegetative Compatibility Group ◽  
Group I ◽  
Compatibility Group ◽  
First Time

Thirty-four isolates of Fusarium oxysporum, obtained in China from cucumber plants showing either Fusarium wilt (F. oxysporum f. sp. cucumerinum) or root and stem rot (F. oxysporum f. sp. radicis-cucumerinum) symptoms, were characterized by pathogenicity, vegetative compatibility, and random amplified polymorphic DNA (RAPD). Of these, 23 isolates were identified by pathogenicity as F. oxysporum f. sp. cucumerinum, and one as F. oxysporum f. sp. radicis-cucumerinum, while 10 isolates were avirulent on cucumber, melon, sponge gourd, and pumpkin. The Chinese isolates of F. oxysporum f. sp. cucumerinum were assigned to RAPD groups III and XXI and to vegetative compatibility group (VCG) 0183, four new VCGs, 0184 to 0187, and a single-member VCG included in the artificial VCG 018-. The Chinese isolate of F. oxysporum f. sp. radicis-cucumerinum was assigned to RAPD group I and bridging VCG 0260/0261. The occurrence of F. oxysporum f. sp. radicis-cucumerinum on cucumber is reported for the first time in China.

scholarly journals Enzymotherapy of toxic anterior segment syndrome after phacoemulsification

2017 ◽  
Vol 10 (2) ◽  
pp. 87-93
Author(s):  
Alexander S Suvorov ◽  
Timur G Sazhin
Keyword(s):  
Visual Acuity ◽  
Anterior Chamber ◽  
Treatment Initiation ◽  
Anterior Segment ◽  
Treatment Result ◽  
Eye Drops ◽  
Group Iii ◽  
Group I ◽  
Toxic Anterior Segment Syndrome ◽  
Observation Period

Purpose. To investigate the efficacy of recombinant prourokinase (RPU) treatment in patients with toxic anterior segment syndrome after phacoemulsification. Material and methods. We observed 123 patients (123 eyes) with toxic anterior segment syndrome after phacoemulsification; patients of the group I (n = 30) received only antiinflammatory treatment; in treatment of patients of the group II (n = 31), instillations of the RPU solution were used, in the group III (n = 31), RPU solution was injected subconjunctivally, in the group IV (n = 31) - RPU solution electrophoresis was used. Treatment result analysis was carried out within 30 days. Results. Initial mean visual acuity in groups was 0.09 ± 0.04; 0.1 ± 0.04; 0.09 ± 0.04; 0.08 ± 0.04, and was virtually the same (p > 0.05). In 24 hours after treatment initiation, mean visual acuity in the group III was higher, than in the others. In three days and up to the end of observation period, the lowest mean visual acuity was noted in the group I (p < 0.05). Anterior chamber assessment showed that beginning from the first 24 hours after treatment initiation, in groups III and IV, fibrin lysis in the anterior chamber was more pronounced, than in groups I and II (p < 0.05); by the end of the observation period, worst indices of anterior chamber state were found in the group I (p < 0.05), in other groups, they were almost identical (p < 0.05). When using RPU, no allergic reaction was noted. Conclusions. RPU use in combined toxic anterior segment syndrome therapy after phacoemulsification allows increasing visual acuity, reducing convalescence time, and reducing the number of laser dissections. It was established that all methods of RPU administration are effective. RPU may be administered as eye drops on an outpatient basis, receiving efficacy similar to other administration methods.

scholarly journals Changes in the occurrence of rainfall-induced landslides in Calabria, Southern Italy, in the 20th century

2015 ◽  
Vol 3 (6) ◽  
pp. 3579-3619
Author(s):  
S. L. Gariano ◽  
O. Petrucci ◽  
F. Guzzetti
Keyword(s):  
Southern Italy ◽  
Geographical Area ◽  
Daily Rainfall ◽  
Recent Period ◽  
Rainfall Events ◽  
Rain Gauges ◽  
Entire Observation Period ◽  
Geographical Variations ◽  
The Impact ◽  
Observation Period

Abstract. We exploit a catalogue of 1466 rainfall events with landslides in the 90 year period 1921–2010 to study temporal and geographical variations in the occurrence of landslides in Calabria, Southern Italy. We use daily rainfall records obtained by a network of 318 rain gauges to reconstruct 448 493 rainfall events. Combining the rainfall and the landslide information, we obtain a catalogue of 1466 rainfall events with landslides (REL) in Calabria from 1921 to 2010, where a REL is the occurrence of one or more landslide during or immediately after a rainfall event. We find that the geographical and the temporal distributions of the rainfall-induced landslides have changed in the observation period. The average and the maximum values of the cumulated event rainfall that have resulted in landslides in the recent-most 30 year period 1981–2010 are lower than the values necessary to trigger landslides in previous periods, whereas the duration of the rainfall events that triggered landslides has remained the same. This can be considered evidence of variations in rainfall conditions, but also an increase in the vulnerability of the territory. We further find that the yearly distribution of rainfall-induced landslides has changed in the observation period, analysing the variations in the number of rainfall events with landslides occurred in each month in three 30 year periods. To investigate variations in the impact of REL on the population, we compared the number of REL in each of the 409 municipalities in Calabria, with the size of the population in the municipalities, measured by national Censuses conducted in 1951, 1981, and 2011. For the purpose, we adopted two strategies. The first strategy considered impact as IREL = #REL/P and the second strategy measured impact as RREL = #REL × P, where #REL is the total number of REL in a period, and P is the size of the population in the same period and geographical area. Considering the entire observation period, IREL and RREL have both increased in Calabria. However, considering the changes between the recent period 1981–2010 and the previous period 1951–1980, results are more variegated with a number of municipalities where IREL and RREL have increased, or decreased. Municipalities where IREL has increased are mainly in the mountains, and municipalities where RREL has increased are mainly along the coasts.

scholarly journals EFFECT OF LOCAL UV RADIATION ON THE MORPHOFUNCTIONAL STATE OF THE SKIN OF GUINEA PIGS IN EARLY AND REMOTE PERIODS AFTER IRRADIATION

2020 ◽  
Vol 73 (4) ◽  
pp. 705-707
Author(s):  
Tetyana V. Zvyagintseva ◽  
Svitlana I. Myronchenko ◽  
Nataliia I. Kytsiuk ◽  
Olga V. Naumova
Keyword(s):  
Ultraviolet Irradiation ◽  
Guinea Pigs ◽  
Acute Inflammation ◽  
Elastic Fibers ◽  
Control Group ◽  
Entire Observation Period ◽  
Morphological Picture ◽  
Morphometric Methods ◽  
Observation Period

The aim is to establish the features of morphological and morphometric changes in the skin of guinea pigs in erythemal, early post-erythemal and late post-erythemic periods after local ultraviolet irradiation. Materials and methods: Studies were conducted on 54 albino guinea pigs weighing 400-500 g. Ultraviolet erythema was caused by irradiation in 1 minimum erythemal dose. The control group included intact guinea pigs. After 2, 4 hours, on the 3rd, 8th, 15th, 21st, 28th day, the fragments of the irradiated skin were investigated using histochemical and morphometric methods. Results: After 2, 4 hours after irradiation, dyscirculatory changes in the skin develop. By the 3rd day of the experiment a morphological picture of acute inflammation in the epidermis and dermis develops, apoptotic keratinocytes appear (sunburn cells), which is accompanied by thickening of the epidermis and an increase in the density of fibroblasts. By the 8th day proliferative-hyperplastic and degenerative changes begin to prevail, including dystrophic nature, the thickness of the epidermis and the density of fibroblasts reach a maximum. In the long term, on the 15-28th day, dystrophic changes of the epidermis, dyskeratosis, changes in the number and structure of elastic fibers with an increase in uneven fibrosis, collagenization processes and the development of sclerotic changes, as well as a significant thickening of the epidermis, an increase in the density of fibroblasts are observed. Conclusions: The data obtained indicate pronounced morphofunctional changes in the skin in the zone of local ultraviolet irradiation observed throughout the entire observation period.

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