scholarly journals Correlates of genital Chlamydial trachomatis infection in a cohort of infertile women in Ibadan, Nigeria

2017 ◽  
Vol 6 (9) ◽  
pp. 3754
Author(s):  
Tinuade A. Ajani ◽  
Timothy Abiola Olusesan Oluwasola ◽  
Chinenye G. Anaedobe ◽  
Mustapha A. Ajani ◽  
Samuel A. Fayemiwo ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chlamydia Trachomatis ◽  
Past History ◽  
Sexual Partners ◽  
Female Infertility ◽  
Sexual History ◽  
Systematic Sampling ◽  
Chlamydia Trachomatis Infection ◽  
Infertile Women ◽  
History Of

Background: Genital Chlamydial trachomatis infection, though often asymptomatic, is an established indirect causative agent of female infertility via its activities on the tubal physiology. Many risk factors are postulated for its acquisition and the main thrust of this study was to establish the organisms’ correlates among infertile women attending gynaecologic clinic in Ibadan.Methods: A systematic sampling technique was used on each selected day to recruit women who met the inclusion criteria into the study using a sampling frame of 2. Interviewer-administered questionnaires were used to obtain attributes considered as risk factors for acquiring genital Chlamydia trachomatis infection from 150 consenting infertile women between January and November 2015. These attributes included sexual history, social status, alcohol intake and past history of sexually transmitted infections (STIs). Blood samples and endocervical swabs were subsequently taken for detection of C. trachomatis infection using polymerase chain reaction (PCR). Data analysis was done using SPSS version 20.0.Results: The mean age of the respondents was 34.1±5.6 years and 7.30% were positive for C. trachomatis. Chlamydia trachomatis infection was significantly associated with past history of gonorrhoea, history of multiple sexual partners, husband that has other sexual partners and lifetime sexual partners greater than one.Conclusions: The prevalence of asymptomatic C. trachomatis among infertile women indicated the pathogen as a potential aetiologic agent of female infertility and supported the asymptomatic nature of the infection. The risk factors found to be associated with the organisms’ infection lend out further support to the sexual transmissibility of C. trachomatis.

Risk Factors for Chlamydia Trachomatis Infection in 6810 Young Women Attending Family Planning Clinics

1992 ◽  
Vol 3 (2) ◽  
pp. 117-122 ◽  
Author(s):  
Kristina Ramstedt ◽  
Lars Forssman ◽  
Johan Giesecke ◽  
Fredrik Granath
Keyword(s):  
Risk Factors ◽  
Chlamydia Trachomatis ◽  
Young Women ◽  
Disease Spread ◽  
Sexually Active ◽  
Screening Criteria ◽  
Chlamydia Trachomatis Infection ◽  
Increased Risk ◽  
History Of ◽  
Culture Positive

Screening programmes are important for the control of Chlamydia trachomatis (Ct) infection, a disease spread mainly by asymptomatic carriers. Risk factors for Ct infection were assessed in 6810 consecutive asymptomatic young women seeking contraceptive advice. All women filled in a questionnaire and were offered Ct testing. Of the 5785 who consented to testing, 425 (7.3%) were Ct culture positive. Four variables were significantly related to increased risk of being infected: age 18–23 years, duration of present relationship < 1 year, non-use of condoms, and a history of not having had a previous genital infection. It is not possible to devise screening criteria that would effectively identify women at high risk. Therefore a screening programme should be targeted at all sexually active young people. However, if after some years the programme succeeds in lowering general Ct prevalence, these factors may be important when selecting patients for Ct testing.

scholarly journals Prevalence of Chlamydia trachomatis Infection, Serovar Distribution and Co-Infections with Seven High-Risk HPV Types among Italian Women with a Recent History of Abnormal Cervical Cytology

2019 ◽  
Vol 16 (18) ◽  
pp. 3354 ◽  
Author(s):  
Marianna Martinelli ◽  
Rosario Musumeci ◽  
Alberto Rizzo ◽  
Narcisa Muresu ◽  
Andrea Piana ◽  
...  
Keyword(s):  
Chlamydia Trachomatis ◽  
Screening Program ◽  
Hpv Infection ◽  
Cervical Cytology ◽  
Recent History ◽  
Abnormal Cytology ◽  
Chlamydia Trachomatis Infection ◽  
Hpv Dna ◽  
Abnormal Cervical Cytology ◽  
History Of

Chlamydia trachomatis (Ct) and human papillomavirus (HPV) are the most prevalent sexually transmitted infections throughout the world. Despite the serious complications associated with chronic Ct infections in sexually active women, a screening program is not yet available in Italy. Moreover, HPV/Ct co-infections are also known to occur frequently, increasing the risk of HPV-induced carcinogenesis. The aim of this study was to evaluate the prevalence of Ct infections, the distribution of Ct serovars, and the incidences of Ct/HPV co-infections among women with a recent history of abnormal cervical cytology. Cervical samples were collected from 199 women referred for a gynecological visit following an abnormal Pap test results. All samples were tested for the presence of Ct and HPV DNA using real-time PCR assays; Ct typing of positive samples was performed by PCR–RFLP (restriction fragment length polymorphism) targeting the ompA gene. A high percentage of these women (12.8% and 21.7% with or without abnormal cytology on “retesting”, respectively) were found to be Ct positive. Serovar F was the most prevalent type in Ct positive women, followed by E and K. Ct/HPV co-infections were detected in 7% (14/199) of enrolled women, with HPV-16, HPV-51, and HPV-52 being most frequently identified in co-infections. This study provides new epidemiological data on the prevalence of Ct and associated HPV infection in women with a recent history of abnormal cervical cytology in Italy, where notification of cases is not mandatory.

Prevalence of Neurosyphilis at Government Rajaji Hospital, Madurai, India

1994 ◽  
Vol 5 (4) ◽  
pp. 290-292 ◽  
Author(s):  
R Ganesh ◽  
A Stanley ◽  
Nalini Ganesh ◽  
M K Venkatram ◽  
R Alagappan
Keyword(s):  
Metabolic Disorders ◽  
Past History ◽  
Sexual Partners ◽  
Socioeconomic Background ◽  
Multiple Sexual Partners ◽  
Low Socioeconomic ◽  
Cardiovascular Involvement ◽  
History Of ◽  
The Government ◽  
Meningovascular Syphilis

Forty patients (34 males and 6 females) with neurological complaints/manifestations and with a past history of multiple sexual partners attending the Government Rajaji Hospital, Madurai, India between April 1992 and October 1992 were investigated for neurosyphilis. Metabolic disorders, hypertension, ischaemic heart disease, arrhythmias and trauma were excluded. Seven males (17.5%) were found to have neurosyphilis. The youngest was 26 years old and the oldest was 47. All were married and of low socioeconomic background. Meningovascular syphilis was the predominant presentation (6:1). Associated cardiovascular involvement was noticed in one of the cases. There was no associated HIV infection in these cases. The incidence is higher than previous reports from this centre.

Sexual behaviour of inmates with Chlamydia trachomatis infection in the prisons of Catalonia, Spain

Sexual Health ◽  
2012 ◽  
Vol 9 (2) ◽  
pp. 187 ◽  
Author(s):  
Evelin L. Corbeto ◽  
Dolors Carnicer-Pont ◽  
Rossie Lugo ◽  
Victoria Gonzalez ◽  
Elisabet Bascuñana ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chlamydia Trachomatis ◽  
High Mobility ◽  
Cross Sectional Study ◽  
Multivariate Logistic Regression Model ◽  
Cross Sectional ◽  
Convenience Sample ◽  
Chlamydia Trachomatis Infection ◽  
High Risk Factors ◽  
Independent Risk Factors

Objective To determine the prevalence of Chlamydia trachomatis (CT) and high risk factors for acquisition in preventive prisoners in Catalonia. Methods: Cross-sectional study of a convenience sample of 478 prisoners aged between 18 and 35 years was analysed using real-time polymerase chain reaction. A standardized questionnaire was used to collect behavioural data. Significant differences were analysed in the descriptive study using Pearson’s χ2. The association between CT and its determinants was analysed using the Mantel–Haenszel test and a multivariate logistic regression model. Results: The overall prevalence of CT was 5.4%. The independent risk factors for infection by CT were as follows: foreign origin, having had concurrent sexual partners, and alcohol consumption. Conclusions: This is the first study performed in prisons of Catalonia that shows the prevalence of CT in young prisoners. The high mobility of young detainees could explain the similarity in prevalence obtained about young people in Catalonia. Systematic monitoring of CT infection in young preventive prisoners is important in order to prevent further problems in themselves and in the general population, since they become a ‘bridge population’ in sexually transmissible infection spreading.

Colonoscopic Screening of Persons With Suspected Risk Factors far Colon, Cancer: II. Past History of Colorectal Neoplasms

1989 ◽  
Vol 96 (2) ◽  
pp. 299-306 ◽  
Author(s):  
Seymour Grossman ◽  
Mary L. Milos ◽  
Irene S. Tekawa ◽  
Nicholas P. Jewell
Keyword(s):  
Risk Factors ◽  
Colon Cancer ◽  
Colorectal Neoplasms ◽  
Past History ◽  
History Of

A case–control study of risk factors for multiple sclerosis in Iran

2011 ◽  
Vol 17 (5) ◽  
pp. 550-555 ◽  
Author(s):  
Alvaro Alonso ◽  
Stuart D Cook ◽  
Amir-Hadi Maghzi ◽  
Afshin A Divani
Keyword(s):  
Risk Factors ◽  
Multiple Sclerosis ◽  
Case Control Study ◽  
Past History ◽  
Multivariable Analysis ◽  
Case Control ◽  
Sunlight Exposure ◽  
Farm Animals ◽  
History Of ◽  
Control Study

Background: Numerous studies have assessed risk factors for multiple sclerosis (MS), although none have been conducted previously in Iran. Objective: The objective of this study was to study lifestyle and environmental risk factors of MS in the Iranian population. Methods: A case–control study, including 394 MS cases and 394 matched controls, was conducted in MS clinics in different Iranian cities. Information on lifestyles, environmental exposures, and past medical history was obtained from medical charts and phone interviews. Results: In multivariable analysis, sunlight exposure was associated with a lower risk of MS: the odds ratio (OR) and 95% confidence interval (CI) of MS associated with a 1-h increment in daily sunlight was 0.62 (0.53–0.73). Smoking was associated with MS risk in women (OR: 6.48, 95% CI: 1.46–28.78), but not in men (OR: 0.72, 95% CI: 0.31–1.68) ( p = 0.002 for interaction). Finally, past history of common surgical procedures, infectious disorders, or exposure to pets and farm animals was not associated with MS risk. Conclusions: Different modifiable lifestyles, including sunlight exposure and smoking, were associated with lower MS risk in Iran. Interventions aimed at promoting smoking cessation and, more importantly, at increasing exposure to sunlight might contribute to the prevention of MS.

Risk Factors for Incident and Redetected Chlamydia trachomatis Infection in Women

2016 ◽  
Vol 43 (2) ◽  
pp. 113-119 ◽  
Author(s):  
Elise Harder ◽  
Louise T. Thomsen ◽  
Kirsten Frederiksen ◽  
Christian Munk ◽  
Thomas Iftner ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chlamydia Trachomatis ◽  
Chlamydia Trachomatis Infection

scholarly journals Prognosis of the development of pneumonia in children at the outbreak of respiratory mycoplasmosis

2017 ◽  
Vol 98 (6) ◽  
pp. 921-927 ◽  
Author(s):  
S P Kokoreva ◽  
O A Razuvaev
Keyword(s):  
Risk Factors ◽  
Past History ◽  
Binary Logistic Regression ◽  
Control Group ◽  
Mycoplasma Pneumonia ◽  
Focus Of Infection ◽  
History Of ◽  
Mycoplasmal Pneumonia ◽  
And Control

Aim. To identify risk factors for mycoplasma pneumonia at the outbreak of respiratory mycoplasmosis in the children’s collective using a comprehensive statistical analysis. Methods. 120 children aged 12-15 years from the focus of respiratory mycoplasmosis outbreak were observed. They were divided into two groups: study group - 33 children with mycoplasma pneumonia, and control group - 56 children from the focus of infection, 14 of which during the observation period had no disease simptoms, and 42 children had other forms of respiratory mycoplasmosis. Results. 6 factors influencing the development of mycoplasma pneumonia were identified in children from the focus of respiratory mycoplasmosis outbreak. The correlation analysis was performed and one-dimensional models of the chance of developing pneumonia were constructed by calculating odds ratios. Past history of pneumonia increases the risk for pneumonia by 23.46 times, passive smoking in a child - by 2.77 times. At the same time, emergency prevention with immunotropic drugs reduces the risk for pneumonia by 8.93 times, daily walking - by 3.31 times, walking for more than 2 hours - by 3.83 times, increasing fruit in the diet - by 3.09 times and taking multivitamins - by 2.56 times compared to cases when these measures were not taken. The binary logistic regression was calculated to build a multidimensional research model. The sensitivity of this model was 87.88%, specificity - 91.07%. Conclusion. At the outbreak of respiratory mycoplasmosis the risk factors for the development of mycoplasmal pneumonia are pneumonia in past medical history, smoking in a child’s family; preventive measures are long-term daily exposure to fresh air, emergency prevention with immunotropic, complex multivitamin preparations with trace elements and lactic acid bacteria, dietary intake corrected for fruit intake.

scholarly journals Sexually transmitted infections, the silent partner in HIV-infected women in Zimbabwe

2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Sara Lowe ◽  
Tinashe Mudzviti ◽  
Ardele Mandiriri ◽  
Tinei Shamu ◽  
Petronella Mudhokwani ◽  
...  
Keyword(s):  
Risk Factors ◽  
Sexually Transmitted Infections ◽  
Trichomonas Vaginalis ◽  
Tertiary Education ◽  
Sexual Partners ◽  
Sexual History ◽  
People Living With Hiv ◽  
Cross Sectional ◽  
Sexually Transmitted ◽  
Asymptomatic Patients

Background: Coinfection rates of HIV and sexually transmitted infections (STIs) are not widely reported in Zimbabwe and no local guidelines regarding the screening of STIs in people living with HIV exist.Objectives: This cross-sectional study was conducted to determine the prevalence and associated risk factors for STI coinfection in a cohort of HIV-infected women.Methods: Between January and June 2016, 385 HIV-infected women presenting for routine cervical cancer screening were tested for five STIs: Neisseria gonorrhoeae (NG), Chlamydia trachomatis(CT), Trichomonas vaginalis (TV), Herpes Simplex Virus (HSV) type 2 and Treponema pallidum (TP). Socio-demographic characteristics and sexual history were recorded. Multiple logistic regression was used to identify factors associated with the diagnosis of non-viral STIs.Results: Two hundred and thirty-three participants (60.5%) had a confirmed positive result for at least one STI: HSV 2 prevalence 52.5%, TV 8.1%, CT 2.1%, NG 1.8% and TP 11.4%. Eighty-seven per cent of the women were asymptomatic for any STI; 62.3% of women with a non-viral STI were asymptomatic. Women who had attended tertiary education were 90% less likely to have a non-viral STI (adjusted odds ratio [aOR]: 0.10, 95% confidence interval [CI]: 0.03–0.39, p < 0.01). Having more than three lifetime sexual partners was a significant predictor for a non-viral STI diagnosis (aOR: 3.3, 95% CI: 1.5–7.2, p < 0.01).Conclusion: A high prevalence of predominantly asymptomatic STIs is reported in a cohort of HIV-infected women. Syndromic management results in underdiagnosis of asymptomatic patients. More than three lifetime sexual partners and less formal education are risk factors for coinfection with non-viral STI. High-risk women should be screened using aetiological methods.

scholarly journals Prevalence of hyperemesis gravidarum and associated risk factors among pregnant women in a tertiary health facility in Northeast, Nigeria

2020 ◽  
Vol 9 (9) ◽  
pp. 3557
Author(s):  
Muhammad B. Aminu ◽  
Mohammed Alkali ◽  
Bala M. Audu ◽  
Toyin Abdulrazak ◽  
Dauda Bathna
Keyword(s):  
Risk Factors ◽  
Pregnant Women ◽  
Hyperemesis Gravidarum ◽  
Past History ◽  
Tertiary Hospital ◽  
Grand Multiparity ◽  
History Of ◽  
Associated Risk Factors ◽  
Age Range ◽  
Northeast Nigeria

Background: One of the commonest symptoms observed in pregnant women before the 20th week of gestation is nausea and vomiting, an exaggeration of these symptoms hyperemesis gravidarum (HEG) could result in maternal and fetal catastrophes and even death. The objective of this study was to determine the prevalence and associated risk factors for hyperemesis gravidarum among pregnant women at booking.Methods: A prospective institutional based study design was done among 452 pregnant women seen at booking in a tertiary hospital in Northeast Nigeria from the 1st February 2019 to 30th June 2019. Data was summarized using descriptive statistics. OR was used to measure significant risk.Results: The observed prevalence of hyperemesis gravidarum among pregnant women in the study is 44.9%. The Majority (81.4%) of these women were between the age range of 21 and 35 years. Mean age of 27 years. Multiparity (33.4%), previous (44.9%) and family history of HEG (31.6%) were identified as important risk factors for developing HEG. Grand multiparity (11.5%) and gestational age less than 13 weeks (6.64%) were however less likely observed to be risks for HEG.Conclusions: HEG is a common problem in pregnancy with almost half of the number of pregnant women at booking affected. Multiparity and past history of HEG are pointers to developing the condition and it should be looked out for among at risk group of pregnant women, so that early intervention can be instituted to avoid any possible adverse outcome.

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