scholarly journals Prognosis of the development of pneumonia in children at the outbreak of respiratory mycoplasmosis

2017 ◽  
Vol 98 (6) ◽  
pp. 921-927 ◽  
Author(s):  
S P Kokoreva ◽  
O A Razuvaev
Keyword(s):  
Risk Factors ◽  
Past History ◽  
Binary Logistic Regression ◽  
Control Group ◽  
Mycoplasma Pneumonia ◽  
Focus Of Infection ◽  
History Of ◽  
Mycoplasmal Pneumonia ◽  
And Control

Aim. To identify risk factors for mycoplasma pneumonia at the outbreak of respiratory mycoplasmosis in the children’s collective using a comprehensive statistical analysis. Methods. 120 children aged 12-15 years from the focus of respiratory mycoplasmosis outbreak were observed. They were divided into two groups: study group - 33 children with mycoplasma pneumonia, and control group - 56 children from the focus of infection, 14 of which during the observation period had no disease simptoms, and 42 children had other forms of respiratory mycoplasmosis. Results. 6 factors influencing the development of mycoplasma pneumonia were identified in children from the focus of respiratory mycoplasmosis outbreak. The correlation analysis was performed and one-dimensional models of the chance of developing pneumonia were constructed by calculating odds ratios. Past history of pneumonia increases the risk for pneumonia by 23.46 times, passive smoking in a child - by 2.77 times. At the same time, emergency prevention with immunotropic drugs reduces the risk for pneumonia by 8.93 times, daily walking - by 3.31 times, walking for more than 2 hours - by 3.83 times, increasing fruit in the diet - by 3.09 times and taking multivitamins - by 2.56 times compared to cases when these measures were not taken. The binary logistic regression was calculated to build a multidimensional research model. The sensitivity of this model was 87.88%, specificity - 91.07%. Conclusion. At the outbreak of respiratory mycoplasmosis the risk factors for the development of mycoplasmal pneumonia are pneumonia in past medical history, smoking in a child’s family; preventive measures are long-term daily exposure to fresh air, emergency prevention with immunotropic, complex multivitamin preparations with trace elements and lactic acid bacteria, dietary intake corrected for fruit intake.

scholarly journals PRIORITY RECOMMENDATIONS FOR SOLVING THE PROBLEM OF CHILDREN OBESITY BASED ON THE RESULTS OF THE RESEARCH

2021 ◽  
Vol 74 (5) ◽  
pp. 1099-1103
Author(s):  
Viktor A. Ohniev ◽  
Kateryna H. Pomohaibo ◽  
Mihail I. Kovtun
Keyword(s):  
Risk Factors ◽  
Medical Care ◽  
Children And Adolescents ◽  
Overweight And Obesity ◽  
Control Group ◽  
Obese Children ◽  
Primary Medical Care ◽  
Children Obesity ◽  
History Of ◽  
And Control

The aim: Of the work was to study and evaluate the risk factors and the level of primary medical care for children with overweight and obesity. Materials and methods: A sociological survey was conducted in main (413 persons) and control group (396 persons) and the copying from the history of the child’s development (f.112/a) of 280 obese children was conducted. Results: It was defined that on the development of excess weight in children and adolescents, biological and social and hygienic factors had a significant impact (η ≥ 3%; p<0,001) and that the level of primary medical care for obese children (proved diagnosis of obesity in the history of the child (f. №.112/а) had only 61,7±2,7% of patients) was insufficient. Conclusions: Identification of comprehensive priority activities for solving problem of children overweight and obesity based on the results of conducted research were done.

scholarly journals Plantar Fasciitis Risk Factorsin Normal Population

2018 ◽  
Vol 15 (2) ◽  
pp. 427-430
Author(s):  
Hadi Ghotbi Joshvaghan ◽  
Farzad Omidi-Kashani
Keyword(s):  
Risk Factors ◽  
Plantar Fasciitis ◽  
Normal Population ◽  
Control Group ◽  
Control Groups ◽  
Orthopedic Surgeon ◽  
History Of ◽  
The Difference ◽  
And Control ◽  
Bony Spur

Conservative treatments results for plantar fasciitis patients are inconsistent and therefore manipulating risk factors could be the best option for this disease. To determine risk factors of plantar fasciitis. In a retrospective study, all patients who had plantar fasciitis were enrolled and were compared to control group on their demographic characteristics. The angle of dorsi-flexion was recorded by examination of orthopedic surgeon, history of pregnancy and time of standing in one day. Plantar curvature was measured by orthopedic surgeon. Female sex percentage was significantly higher in PF group than male sex (p=0.007), but the difference in sex was not significant between PF and control groups (p=0.22). Body mass index (BMI) above 30 was significantly higher in PF group compare to control group (p=0.013). Presence of bony spur was significantly higher in PF group compare to control group (p=0.03). There were significant differences in foot curve degree in patients between PF and control groups (p=0.037). Odds ratio (OR) of plantar fasciitis was 1.65 times in patients with bony spur. History of pregnancy increase OR of plantar fasciitis 1.37 times (OR:1.37; 95% CI:1.20-1.82, p=0.017). Plantar fasciitis is associated with higher BMI, pregnancy, bony spur and foot curve cavus. However, it seems that a predisposing foot structural factor should also be accompanied with these risk factors.

scholarly journals Risk factors of bronchiolitis

2013 ◽  
Vol 53 (1) ◽  
pp. 21
Author(s):  
I Gde Doddy Kurnia Indrawan ◽  
IB Subanada ◽  
Rina Triasih
Keyword(s):  
Risk Factors ◽  
Cigarette Smoke ◽  
Preterm Infants ◽  
Exclusive Breastfeeding ◽  
Statistical Significance ◽  
Control Group ◽  
Case Group ◽  
History Of ◽  
Matched Case ◽  
And Control

Background Bronchiolitis peak incidence is in children aged 2 -6months. History of atopy in parents, non-exclusive breastfeeding,exposure to cigarette smoke, and infants living in crowded areasmay be risk factors for bronchiolitis. Gestational of age at birth isalso influences the mortality oflower respiratory tract infection.Objective To evaluate the following conditions as possiblerisk factors for bronchiolitis: history of atopy, non-exclusivebreastfeeding, preterm infants, exposure to cigarette smoke, and2:: 6 persons residing in the home.Methods A sex-matched case-control study was conductedby collecting data from medical records at Sanglah Hospital,Denpasar. The case group subjects met the diagnostic criteriafor bronchiolitis and were aged 1-24 months. The control groupincluded patients with diagnoses unrelated to the respiratorysystem. Data was analyzed using bivariate (Mc.N emar) andmultivariate methods (logistic regression) with 95% confidenceintervals and statistical significance value of P <0 .05.Results There were 96 subjects in our study, consisted of 48subjects in the case group and 48 in the control group. Thecase and control groups were similar in baseline characteristics.The presence of history of atopy (OR 34.7; 95%CI 3 to 367,P=0.003), non-exclusive breastfeeding (OR 4.3; 95%CI 1.4 to13, P=0.010), exposure to cigarette smoke (OR 3; 95%CI 1 to9.2, P=0.047), and 2:: 6 persons living in the home (OR 7.9;95%CI 2.6 to 24, P<0.0001) were found to be significant riskfactors for bronchiolitis, while the preterm infants seem notsignificant as a risk factor of bronchiolitis (OR3; 95%CI 0.31 to78.99, P=0.625).Conclusion History of atopy, non-exclusive breastfeeding,exposure to cigarette smoke, and 2:: 6 persons living in the homeare found to be risk factors, while preterm infants seem not a riskfactor for bronchiolitis.

scholarly journals Association of gene polymorphisms with women urinary incontinence

Open Medicine ◽  
2021 ◽  
Vol 16 (1) ◽  
pp. 1190-1197
Author(s):  
Povilas Aniulis ◽  
Aurelija Podlipskyte ◽  
Alina Smalinskiene ◽  
Rosita Aniuliene ◽  
Mindaugas Jievaltas
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Urinary Incontinence ◽  
Gene Polymorphism ◽  
Adrenergic Receptor ◽  
Gene Polymorphisms ◽  
Serotonin Receptor ◽  
Control Group ◽  
History Of ◽  
And Control

Abstract Aim of study was set to investigate the association of women urinary incontinence (UI) with serotonin receptor HTR2A T102C and beta 3-adrenergic receptor ADRB3 Trp64Arg genes polymorphisms. The study included 110 women with Urge, Stress, and Mixed UI types and the control group – 105 continent women. Both groups have filled in the ICIQ-FLUTS questionnaire and their blood genotyping was performed. Urge UI subgroup was older and had higher body mass index (BMI) in comparison to other UI types and control group. More than half of all women had family history of UI in Stress UI and Mixed UI subgroups. The frequency of HTR2A T102C gene polymorphism’s minor allele C and genotype CC was significantly more expressed in Urge UI subgroup, as compared with control group (C-77.3 vs 58.7%, p = 0.007 and CC-57.6 vs 31.1%, p = 0.015). The ADRB3 Trp64Arg gene polymorphism did not differ between groups. The regression analysis revealed CC genotype (OR = 3.06, 95% CI: 1.11–8.43; p = 0.030) and allele C (OR = 2.53, 95% CI: 1.16–5.53; p = 0.020) were risk factors for development of Urge UI. We conclude that HTR2A T102C gene polymorphism affected the development of Urge UI.

scholarly journals RISK FACTORS FOR MULTIPLE SCLEROSIS IN VOLYN REGION (UKRAINE)

2016 ◽  
Vol 6 ◽  
pp. 45-51
Author(s):  
Nataliia Bobryk ◽  
Larysa Sokolova
Keyword(s):  
Risk Factors ◽  
Multiple Sclerosis ◽  
Paternal Age ◽  
Control Group ◽  
Number Of Patients ◽  
History Of ◽  
One Year ◽  
Associated Risk Factors ◽  
Simplex Virus

The prevalence rate of multiple sclerosis (MS) in Volyn Region (101.0 per 100000) is the highest in Ukraine. To study MS risk factors in Volyn Region, special questionnaires were distributed among all MS patients residing in Volyn region. Results were obtained from 227 respondents including 154 women and 73 men of mean age 43±10.6 years. The control group included 105 healthy respondents inhabiting Volyn region. We found associated risk factors for MS to be: mother of Volyn origin, maternal age after 27 years old and paternal age after 29 years old at birth of respondent, subject's born as a third child, brestfeeding for less than one year, living in the zone of industrial pollution, near mobile, TV- and radio re-translators, full traffic automobile roads, time spending outdoors less than one hour in winter and less than eight hours in summer, consumption of fruit and vegetables less than 5 times a week, of beef less than 3 times a week, poultry meet less than 3, berries less than 3, cereals less than 4 times a week, chronic stressful situations in life. Patients with MS more frequently reported AVRI, hepatitis and herpes simplex virus. Among patients with MS there were fewer respondents with history of chickenpox, rubella and DPT (diphtheria, pertussis, tetanus), BCG immunizations. Here, we introduced a novel study of MS risk factors within Volyn Region. The Registry established in 2012 is being constantly updated and can be a database for a long-term retrospective study involving a large number of patients.

scholarly journals Faktor Risiko Kematian Ibu

2013 ◽  
Vol 7 (10) ◽  
pp. 453
Author(s):  
Nurul Aeni
Keyword(s):  
Risk Factors ◽  
Maternal Mortality ◽  
Maternal Mortality Ratio ◽  
Control Group ◽  
P Value ◽  
Case Group ◽  
Group Data ◽  
Mortality Ratio ◽  
History Of ◽  
And Control

Angka Kematian Ibu (AKI) di Kabupaten Pati bergerak fluktuatif dan menunjukkan status tertinggi pada tahun 2011 dengan 126 per 100.000 kelahiran hidup. Tujuan penelitian ini adalah menggambarkan kematian ibu di Kabupaten Pati dan menganalisis faktor risiko kematian maternal di Kabupaten Pati Tahun 2011. Penelitian menggunakan pendekatan observasional analitik dengan metode kasus kontrol. Jumlah sampel adalah 24 untuk setiap kelompok kasus dan kelompok kontrol. Analisis data menggunakan uji univariat, bivariat dan multivariat. Hasil dari penelitian adalah tiga penyebab utama kematian ibu di Kabupaten Pati adalah penyakit jantung, preeklamsi/eklamsi, dan perdarahan. Kematian ibu tersebar di 16 kecamatan dari 21 kecamatan yang ada dan sebagian besar kematian terjadi pada masa nifas. Analisis regresi logistik menunjukkan bahwa faktor yang berpengaruh terhadap kematian ibu adalah komplikasi kehamilan (OR = 12,198, nilai p = 0,010), komplikasi persalinan (OR = 9,94, nilai p = 0,020) dan riwayat penyakit (OR = 27,735, nilai p = 0,011). Secara bersama-sama, ketiga variabel tersebut berkontribusi terhadap 64,3% kematian ibu yang terjadi di Kabupaten Pati Tahun 2011.Maternal Mortality Ratio (MMR) of Pati Regency fluctuated and showed the highest state in 2011 with 126 per 100.000 live births. This research aimed to describe maternal mortality cases in Pati Regency and to analyze risk factors of maternal mortality happened in 2011. This research used observational analysis, i.e. cases control study. The number of samples was 24 in each of case group and control group. Data was analyzed with univariate, bivariate, and multivariate. This research resulted that three major causes of maternal mortality were heart disease, preeclampsia/eclampsia, and hemorrhage. Maternal mortality spread on 16 from 21 sub-districts on Pati Regency and the majority of them happened in post delivery period. Logistic regression analysis concluded that risk factors influenced maternal mortality were pregnancy complication (OR = 12.198, p value = 0.010), delivery complication (OR = 9.94, p value = 0.020) and history of illness (OR = 27.735, p value = 0.011). Collectively, those variables contributed to 64.3% of maternal mortality in Pati Regency 2011.

scholarly journals Risk Factors of Recurrent Wheeze in Infancy

2017 ◽  
Vol 41 (1) ◽  
pp. 9-14
Author(s):  
Samiha Amin ◽  
ARM Luthful Kabir
Keyword(s):  
Risk Factors ◽  
Allergic Rhinitis ◽  
Atopic Dermatitis ◽  
Tobacco Smoke ◽  
Past History ◽  
Group Versus ◽  
Control Group ◽  
Study Group ◽  
History Of ◽  
Recurrent Wheeze

Background: Recurrent wheeze in infancy is a common clinical problem and one of the most important causes of health facility visits in Bangladesh. Recurrent wheeze is an important manifestation of bronchiolitis, pneumonia and asthma.Objectives: The study was conducted to identify the risk factors associated with recurrent wheeze in infancy.Methods: This case control study was conducted at Dhaka Shishu Hospital and Dhaka Medical College Hospital (DMCH) during August 2008- June 2009 including 50 infants (1- 12 months of age) with recurrent (3 or more) wheeze or wheeze persisting for more than one month during first year of life as study group and 50 children (12 months to 24 months of age) who had no wheeze during first year of life as control groupResults: The study group comprised of 34 (68.0%) male and 16(32.0%) female infants and control group included 31(62.0%) male and 19 (38.0 %) female children. The mean age of study group was 9 months and that of the control group was 18 months. The median age of first attack of wheeze was 4 months. Twenty one (42.0%) infants in study group and 29 (58.0%) in control group were exclusively breastfed. On the other hand, 29 (58.0%) studied cases and 21(42.0%) controls were mixed fed (formula, cow’s milk, suji along with breast milk).The study children who were exclusively breastfed had lesser incidence of recurrent wheeze than those who were mixed fed but the difference was not significant (P> 0.05). There was past history of bronchiolitis in 45 (90.0%) cases of study group in comparison to only 3 (6.0%) cases of control group (p <0.05). Past history of pneumonia was present in 15 (30.0%) cases of study group compared to only 3 (6.0%) cases of control group (P <0.05). There was history of mother’s asthma among 14 (28.0%) infants of study group versus only 1 (2.0%) mother of control group (P <0.05). There was history of father’s asthma in 8 (16.0%) cases of study group in comparison to none of control group (P<0.05). In this study we observed that 11 (22.0%) infants of study group had sibs suffering from wheeze compared to only 3 (6.0%) children of control group (<0.05). Sixteen (32.0%) infants of study group versus only 6 (12.0%) children of control group had atopic dermatitis and 33 (66.0%) cases of study group had suffered from allergic rhinitis whereas only 10 (20.0%) children had allergic rhinitis in control group (P<0.05). Atopic dermatitis and allergic rhinitis among study children were significantly associated with recurrent wheeze during infancy. Twenty (40.0%) study cases had exposure to tobacco smoke compared to 22 (44.0%) cases of control group. Exposure to tobacco smoke was not found to be associated with recurrent wheeze (P >0.05)Conclusion: The risk factors of recurrent wheeze in infancy identified in this study were past history of bronchiolitis , past history of pneumonia, asthma in parents (father and mother), wheeze in other sibs and atopic condition in children (atopic dermatitis, allergic rhinitis). Exclusively breastfed children had lesser incidence of recurrent wheeze than those who were mixed fed but the difference was not significant and exposure to tobacco smoke was not associated with recurrent wheeze in infancy in the present study.Bangladesh J Child Health 2017; VOL 41 (1) :9-14

CARDIOVASCULAR RISK FACTORS PECULIARITIES IN MEN UNDER 60 YEARS OLD WITH MYOCARDIAL INFARCTION AND CHRONIC INFLAMMATORY LUNG DISEASES

2020 ◽  
pp. 21-25
Author(s):  
Tupitsyn V.V. ◽  
Bataev Kh.M. ◽  
Men’shikova A.N. ◽  
Godina Z.N.
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Heart Disease ◽  
Cardiovascular Risk ◽  
Digestive System ◽  
Control Group ◽  
Study Group ◽  
Type I ◽  
Internal Organs ◽  
History Of

Relevance. Information about the cardiovascular diseases risk factors (CVD RF) for in men with chronic lung inflam-matory pathology (CLID) is contradictory and requires clarification. Aim. To evaluate the peculiarities of CVD RF in men under 60 years of age with CLID in myocardial infarction (MI) to improve prevention. Material and methods. The study included men aged 19-60 years old with type I myocardial infarction. Patients are divided into two age-comparable groups: I - the study group, with CLID - 142 patients; II - control, without it - 424 patients. A comparative analysis of the frequency of observation of the main and additional cardiovascular risk fac-tors in groups was performed. Results. In patients of the study group, more often than in the control group we observed: hereditary burden of is-chemic heart disease (40.8 and 31.6%, respectively; p = 0.0461) and arterial hypertension (54.2 and 44.6%; p = 0.0461), frequent colds (24.6 and 12.0%; p = 0.0003), a history of extrasystoles (19.7 and 12.7%; p = 0.04); chronic foci of infections of internal organs (75.4 and 29.5%; p˂0.0001), non-ulcer lesions of the digestive system (26.1 and 14.6%; p = 0.007), smoking (95.1 and 66.3%; p˂0.0001), MI in winter (40.8 and 25.9%; p = 0.006). Less commonly were observed: oral cavity infections (9.2 and 23.6%; p˂0.0001); hypodynamia (74.5 and 82.5%; p = 0.0358), over-weight (44.4 and 55.2%; p = 0.0136), a subjective relationship between the worsening of the course of coronary heart disease and the season of the year (43.7 and 55.2%; p = 0.0173) and MI - in the autumn (14.1 and 21.9%; p = 0.006) period. Conclusions. The structure of CVD RF in men under 60 years of age with CLID with MI is characterized by the pre-dominance of smoking, non-ulcer pathology of the digestive system, frequent pro-student diseases, meteorological dependence, a history of cardiac arrhythmias and foci of internal organ infections. It is advisable to use the listed factors when planning preventive measures in such patients.

THE RISK FACTORS OF MOLAR PREGNANCY

2017 ◽  
pp. 53-58
Author(s):  
Lam Huong Le
Keyword(s):  
High Risk ◽  
Gestational Trophoblastic Disease ◽  
Living Standard ◽  
Control Group ◽  
Uterine Perforation ◽  
Molar Pregnancy ◽  
Health It ◽  
Pregnancy Risk ◽  
History Of ◽  
And Control

Objectives: Molar pregnancy is the gestational trophoblastic disease and impact on the women’s health. It has several complications such as toxicity, infection, bleeding. Molar pregnancy also has high risk of choriocarcinoma which can be dead. Aim: To assess the risks of molar pregnancy. Materials and Methods: The case control study included 76 molar pregnancies and 228 pregnancies in control group at Hue Central Hospital. Results: The average age was 32.7 ± 6.7, the miximum age was 17 years old and the maximum was 46 years old. The history of abortion, miscarriage in molar group and control group acounted for 10.5% and 3.9% respectively, with the risk was higher 2.8 times; 95% CI = 1.1-7.7 (p<0.05). The history of molar pregnancy in molar pregnancy group was 9.2% and the molar pregnancy risk was 11.4 times higher than control group (95% CI = 2.3-56.4). The women having ≥ 4 times births accounted for 7.9% in molar group and 2.2% in control group, with the risk was higher 3.8 times, 95% CI= 1.1-12.9 (p<0.05). The molar risk of women < 20 and >40 years old in molar groups had 2.4 times higher than (95% CI = 1.1 to 5.2)h than control group. Low living standard was 7.9% in molar group and 1.3% in the control group with OR= 6.2; 95% CI= 1.5-25.6. Curettage twice accounted for 87.5%, there were 16 case need to curettage three times. There was no case of uterine perforation and infection after curettage. Conclusion: The high risk molar pregnancy women need a better management. Pregnant women should be antenatal cared regularly to dectect early molar pregnancy. It is nessecery to monitor and avoid the dangerous complications occuring during the pregnancy. Key words: Molar pregnancy, pregnancy women

scholarly journals The Anti-PD-1/PD-L1 Immunotherapy for Gastric Esophageal Cancer: A Systematic Review and Meta-Analysis and Literature Review

2021 ◽  
Vol 28 ◽  
pp. 107327482199743
Author(s):  
Ke Chen ◽  
Xiao Wang ◽  
Liu Yang ◽  
Zheling Chen
Keyword(s):  
Overall Survival ◽  
Esophageal Cancer ◽  
Survival Rate ◽  
Meta Analysis ◽  
Response Rates ◽  
Control Group ◽  
Term Survival ◽  
Long Term Survival ◽  
And Control

Background: Treatment options for advanced gastric esophageal cancer are quite limited. Chemotherapy is unavoidable at certain stages, and research on targeted therapies has mostly failed. The advent of immunotherapy has brought hope for the treatment of advanced gastric esophageal cancer. The aim of the study was to analyze the safety of anti-PD-1/PD-L1 immunotherapy and the long-term survival of patients who were diagnosed as gastric esophageal cancer and received anti-PD-1/PD-L1 immunotherapy. Method: Studies on anti-PD-1/PD-L1 immunotherapy of advanced gastric esophageal cancer published before February 1, 2020 were searched online. The survival (e.g. 6-month overall survival, 12-month overall survival (OS), progression-free survival (PFS), objective response rates (ORR)) and adverse effects of immunotherapy were compared to that of control therapy (physician’s choice of therapy). Results: After screening 185 studies, 4 comparative cohort studies which reported the long-term survival of patients receiving immunotherapy were included. Compared to control group, the 12-month survival (OR = 1.67, 95% CI: 1.31 to 2.12, P < 0.0001) and 18-month survival (OR = 1.98, 95% CI: 1.39 to 2.81, P = 0.0001) were significantly longer in immunotherapy group. The 3-month survival rate (OR = 1.05, 95% CI: 0.36 to 3.06, P = 0.92) and 18-month survival rate (OR = 1.44, 95% CI: 0.98 to 2.12, P = 0.07) were not significantly different between immunotherapy group and control group. The ORR were not significantly different between immunotherapy group and control group (OR = 1.54, 95% CI: 0.65 to 3.66, P = 0.01). Meta-analysis pointed out that in the PD-L1 CPS ≥10 sub group population, the immunotherapy could obviously benefit the patients in tumor response rates (OR = 3.80, 95% CI: 1.89 to 7.61, P = 0.0002). Conclusion: For the treatment of advanced gastric esophageal cancer, the therapeutic efficacy of anti-PD-1/PD-L1 immunotherapy was superior to that of chemotherapy or palliative care.

Sign in / Sign up

Export Citation Format

Share Document