scholarly journals Lipid profile in school children: study from a District of Uttar Pradesh, India

2017 ◽  
Vol 4 (3) ◽  
pp. 719
Author(s):  
Utkarsh Bansal ◽  
Ekansh Rathoria ◽  
Abhishek Gupta ◽  
Nyay Bhai Gupta ◽  
Shwinka Agarwal ◽  
...  
Keyword(s):  
Lipid Profile ◽  
Age Groups ◽  
Uttar Pradesh ◽  
Cross Sectional Study ◽  
Lipid Levels ◽  
Cross Sectional ◽  
Number Of Children ◽  
Prevention Of Atherosclerosis ◽  
Pro Forma

Background:Lipid imbalance when diagnosed in childhood, can forecast the development of atherosclerosis in adulthood and its complications. Therefore, early detection of dyslipidemia should begin in childhood and it should lead to long-term prevention of atherosclerosis by controlling the risk factors. The Objectives of the study were to study lipid profile of children in the age group of 10-19 years and the prevalence of dyslipidemia among them.Methods: This is a cross-sectional study, which was conducted in 300 children aged 10 to 19 years, of either sex, from schools of Barabanki. After getting consent from school authorities, children and their parents, a detailed history was taken with a pre-designed pro forma and fasting blood samples were analyzed for lipid profile.Results:Mean total cholesterol (TC) for boys and girls were 161.06±33.14 mg/dl and 164.68±33.53 mg/dl, LDL-C 99.35±27.41 mg/dl and 101.71±26.44 mg/dl, HDL-C 42.76±5.78 mg/dl and 43.93±5.68 mg/dl, VLDL-C 18.94±4.47 mg/dl and 19.04±4.97 mg/dl and triglycerides (TG) 94.69±22.34 mg/dl and 95.20±24.83 mg/dl respectively. Serum TC, TG, LDL-C, VLDL-C and HDL-C levels were higher in girls than in boys for all age groups. 26.55% boys and 25.20% girls had TC levels above 190 mg/dl. The overall results revealed that 26.0% of children had hypercholesterolemia.Conclusions:The study presents age- and sex-related findings about the dynamics of changes in serum lipid levels in children. Significant number of children had hypercholesterolemia.

scholarly journals Side Effects Following Administration of the First Dose of Oxford-AstraZeneca’s Covishield Vaccine in Bangladesh: A Cross-Sectional Study

2021 ◽  
Vol 13 (4) ◽  
pp. 888-901
Author(s):  
Nishat Jahan ◽  
Fahad Imtiaz Rahman ◽  
Poushali Saha ◽  
Sadia Afruz Ether ◽  
ASM Roknuzzaman ◽  
...  
Keyword(s):  
Side Effects ◽  
Rapid Development ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Post Vaccination ◽  
Long Term Follow Up ◽  
Larger Sample

In response to the raging COVID-19 pandemic, Bangladesh started its vaccine administration in early 2021; however, due to the rapid development and launch of the vaccines in the market, many people had concerns regarding the safety of these vaccines. The purpose of this study was to evaluate the side effects that were experienced by the Bangladeshi residents after receiving the first dose of the Oxford-AstraZeneca’s Covishield vaccine (ChAdOx1nCoV-19). The study was conducted using both online and printed questionnaires and the data were analysed using SPSS. The results included the responses of 474 vaccine recipients from March–April 2021. Pain at the site of injection, fever, myalgia, fatigue and headache were the most commonly reported symptoms, and the overall side effects were found to be significantly more prevalent in the younger population (p ≤ 0.05). These findings were consistent with the results indicated by the clinical trial of ChAdOx1nCoV-19. Logistic regression analysis further revealed that compared to people aged 70 years or above, the incidence of reported side effects was significantly higher in people aged 18–30 years (odds ratio (OR) = 8.56), 31–40 years, (OR = 5.05), 41–50 years (OR = 4.08), 51–60 years (OR = 3.77) and 61–70 years (OR = 3.67). In addition, a significantly higher percentage of female participants suffered from post-vaccination side effects compared to males (OR = 1.51). It was concluded that the Covishield vaccine was well-tolerated among people of different age groups. Nevertheless, further long-term follow-up study with a larger sample size is warranted to establish the long-term safety of the COVID-19 vaccine.

scholarly journals Age-related trends in lipid levels: a large-scale cross-sectional study of the general Chinese population

BMJ Open ◽  
2020 ◽  
Vol 10 (3) ◽  
pp. e034226
Author(s):  
Lei Feng ◽  
Shiyan Nian ◽  
Zongwu Tong ◽  
Ying Zhu ◽  
Ying Li ◽  
...  
Keyword(s):  
Chinese Population ◽  
Age Groups ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Lipoprotein Cholesterol ◽  
Atherosclerotic Cardiovascular Disease ◽  
Sectional Study ◽  
Lipid Levels ◽  
Cross Sectional ◽  
Age Related

ObjectivesThis study aimed to investigate the dynamic trends in total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) levels with ageing.DesignA Chinese population-based cross-sectional study.SettingA physical examination centre of a general hospital.ParticipantsAdult subjects (178 167: 103 461 men and 74 706 women) without a known medical history or treatments that affect lipid metabolism.Main outcome measuresDynamic trends in the above-mentioned lipid parameters with ageing were explored; turning points of age were established using age stratification and validated by fitted multivariate linear regression modelling.ResultsAge was found to be an independent factor extensively associated with lipid levels in both sexes when adjusted for serum glucose, body mass index, lifestyle, drinking and smoking. Age was positively associated with TC, logarithm-transformed TG (LnTG) and LDL-C levels in men ≤40, ≤40 and ≤60 years old (yo) and in women ≤60, ≤70 and ≤60 yo, respectively. Conversely, age correlated negatively with TC, LnTG and LDL-C levels in men ≥61, ≥41 and ≥61 yo and in women ≥61, ≥71 and ≥61 yo, respectively. TC, TG and LDL-C levels in women were initially lower than those in men but surpassed those in men in 51–55, 61–65 and 51–55 yo age groups. The trends in HDL-C levels with age were relatively irregular, although HDL-C levels in women were higher than in men for all age groups.ConclusionsThe definition of dyslipidaemia, the atherosclerotic cardiovascular disease risk assessment and the initiation/goals of statin therapy should fully consider age-related trends in lipid levels and sex differences.

scholarly journals Communication and awareness on a new vaccine: a cross-sectional study in a tertiary care hospital of West Bengal

2019 ◽  
Vol 7 (1) ◽  
pp. 345
Author(s):  
Arup Chakraborty ◽  
Mousumi Datta ◽  
Debjani Guchhait ◽  
Shibaji Gupta
Keyword(s):  
Japanese Encephalitis ◽  
Disease Transmission ◽  
Vaccination Campaign ◽  
Tertiary Care ◽  
Age Groups ◽  
Uttar Pradesh ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Cross Sectional ◽  
Care Givers

Background: Japanese encephalitis (JE) vaccination in India started in 2006 with SA-14-14-2 live attenuated JE vaccine (JEV) following large outbreaks of JE in some districts of Eastern Uttar Pradesh and Bihar in 2005. Age groups 1-15 yrs are first vaccinated with a single dose of JEV in a campaign mode followed by integration of this vaccine in routine immunization. It is beyond doubt that added to vaccination campaigns, proper awareness on JE can play significant role in controlling the disease.Methods: An observational study with cross sectional design was conducted in Kolkata Medical College and Hospital, Kolkata during JE Vaccination campaign during January, 2018 among 85 respondents, to assess the awareness on JE, among care-givers who brought their children for vaccination at the immunization clinic.Results: It was found that only 37.6% the respondents attending the campaign knew the name of the disease; 17.6% respondents were aware about disease transmission, and 5.9% could state two or more clinical features that might be associated with Japanese Encephalitis. 69.4% had no knowledge of up to what age JE vaccines can be administered; 23.5% said it can be administered till the beneficiaries attain fifteen years of age.Conclusions: IEC activities during JE vaccination campaign was not able raise awareness on JE to the desired level. However beneficiaries were informed about service availability and could be mobilised to come for vaccination.

scholarly journals A cross sectional study of lipid profile in stroke patients

2020 ◽  
Vol 7 (4) ◽  
pp. 687
Author(s):  
Nirmala A. C. ◽  
Hrishikesh S.
Keyword(s):  
Lipid Profile ◽  
Serum Lipid ◽  
Cross Sectional Study ◽  
Diabetic Group ◽  
Lipid Lowering ◽  
Lipid Lowering Therapy ◽  
Sectional Study ◽  
Lipid Levels ◽  
Cross Sectional ◽  
Serum Lipid Levels

Background: Atherosclerosis affects multiple vascular beds, accounting for nearly all of coronary heart disease and some proportion of ischemic strokes. Serum lipid levels have an effect on the short-term mortality due to strokes. But in some studies, there was no dyslipidemia in patients who presented with acute stroke. It is important to evaluate the serum lipid levels in both the types of strokes to guide lipid lowering therapy which can reduce incidence of stroke and related mortality. This study is undertaken to evaluate the role of serum lipids in patients of stroke in our centre.Methods: It is a cross sectional study, conducted on 176 patients of stroke, who were assessed by NIHSS stroke scale clinically. Serum lipid profile was measured in all patients. Data was entered in Microsoft Excel and analysed by descriptive statistics. Chi Square test was used for association of qualitative variables. A p value<0.05 was considered statistically significant.Results: In this study conducted on 176 patients, LDL values were deranged more in CVA-bleed group compared to CVA-infarct group. BMI was the best anthropometric measure that correlated with LDL. LDL was also the most common parameter that was deranged in nonsmokers (61.8%) whereas in smokers, total cholesterol (66.3%) was most commonly deranged. Triglyceride and VLDL values were deranged more commonly in diabetic group than in non-diabetic group.  A total of 123 out of 145patinets with CVA- infarct, had deranged lipid profile and among patients with CVA- bleed 24 out of 32 had deranged lipid profile.Conclusions: Results of this study shows significant derangement in lipid profile especially in LDL cholesterol levels in both infarct and bleed group, therefore starting statin therapy would prove to be beneficial in preventing recurrence of stroke.

scholarly journals Predictive markers of transmission in areas with different malaria endemicity in north-eastern Tanzania based on seroprevalence of antibodies against Plasmodium falciparum

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Robert D. Kaaya ◽  
Debora C. Kajeguka ◽  
Johnson J. Matowo ◽  
Arnold J. Ndaro ◽  
Franklin W. Mosha ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
Antibody Response ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Community Based ◽  
Cross Sectional ◽  
Malaria Endemicity ◽  
North Eastern

Abstract Objective A community-based cross-sectional study was done to assess Plasmodium falciparum exposure in areas with different malaria endemicity in north-eastern Tanzania using serological markers; PfAMA-1 and PfMSP-119. Results Bondo had a higher seroprevalence 36.6% (188) for PfAMA-1 as compared to Hai 13.8% (33), χ2 = 34.66, p < 0.01. Likewise, Bondo had a higher seroprevalence 201(36.6%) for PfMSP-1 as compared to Hai 41 (17.2%), χ2 = 29.62, p < 0.01. Anti-PfAMA-1 titters were higher in malaria positive individuals (n = 47) than in malaria negative individuals (n = 741) (p = 0.07). Anti-PfMSP-1 antibody concentrations were significantly higher in malaria-positive individuals (n = 47) than in malaria-negative individuals (n = 741) (p = 0.003). Antibody response against PfAMA-1 was significantly different between the three age groups; < 5 years, 5 to 15 years and > 15 years in both sites of Bondo and Hai. Likewise, antibody response against PfMSP-119 was significantly different between the three age groups in the two sites (p < 0.001). We also found significant differences in the anti-PfAMA-1and anti-PfMSP-119 antibody concentrations among the three age groups in the two sites (p = 0.004 and 0.005) respectively. Immunological indicators of P. falciparum exposure have proven to be useful in explaining long-term changes in the transmission dynamics, especially in low transmission settings.

scholarly journals DYSLIPIDIMIA

2015 ◽  
Vol 22 (07) ◽  
pp. 865-870
Author(s):  
Ashok Kumar Lohano ◽  
Irfan Ahmed Bhatti ◽  
Azhar Iqbal ◽  
Salman Shah Jilani
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Lipid Profile ◽  
Venous Blood ◽  
Age Groups ◽  
Operational Definition ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Lipid Lowering ◽  
Cross Sectional

Objective: To determine the various lipid profile pattern of dyslipidimia in patientsof chronic renal failure. Study design: Cross-sectional study. Place and duration of study:This study was conducted at Nephrology department of Isra University hospital Hyderabadand Medicine Department Civil hospital Nawabshah, from October 2013 to September 2014.Methodology: This study consisted of 237 patients of chronic renal failure asses on detailedhistory regarding chronic renal failure, patients were subject to relevant investigations i.e.fasting lipid profile and venous blood was drawn after 14 hours fasting state in the early morningand sent to laboratory for analysis of fasting lipid profile. Inclusion Criteria were all patients ofchronic renal failure with 1years history, age > 35 to 60 years and either any sex. Diagnosed onthe basis of serum creatinine as define in operational definition. Exclusion Criteria were patientson lipid lowering agents, acute complication of diabetes mellitus such as diabetic keto-acidosis,patients suffering from hypothyroidism, type 1 DM and HTN, lactic-acidosis, hypoglycemia.Results were prepared with help of tables and graphs. Data was analyzed through SPSS software.Results: Out of 237 patients, 113(47.68%) patients were 51 to 60 years of age, 94(39.66%) were41 to 50 years of age and 30(12.66%) were 35 to 40 years as presented in Chart No 1. Theaverage age of the patients was 50.11±6.94 years. There were 54.43% (129/237) male and45.57% (108/237) female. Various lipid profile pattern of dyslipidimia in patients of chronic renalfailure are presented in table-I. Results of fasting lipid profile are Triglycerides high in 86(36.3%),HDL low in 76(32.1%) cases, LDL in high 83(35%) cases, Cholesterol high in 105(44.3%) casesand VLDL-cholesterol high in 68(28.7%). Stratification analysis showed that lipid profile patternof dyslipidemia was insignificant between male and female as presented in table 2. While withrespect to age groups, rate of Cholesterol, triglycerides, LDL-cholesterol was high in above40 years of age groups as compare to 30 to 40 years of age groups. Rate of low HDL wasalso high in above 40 years of age groups as compare to 30 to 40 years as presented in table3. Conclusions: In conclusion, our study demonstrated that dyslipidemia often our patientschronic renal failure. This underscores the need for the first test patients with lipid abnormalitiesearly treatment can prevent cardiovascular events delay chronic kidney disease.

scholarly journals Correlates of Children’s Physical Activity During the Covid-19 Confinement in Portugal

2020 ◽  
Author(s):  
André Pombo ◽  
Carlos Luz ◽  
Luis Paulo Rodrigues ◽  
Carlos Ferreira ◽  
Rita Cordovil
Keyword(s):  
Physical Activity ◽  
Study Design ◽  
Online Survey ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Number Of Children ◽  
Working From Home ◽  
Outdoor Space ◽  
Families With Children

Abstract Objectives: Aiming to understand the role of household variables on the percentage of physical activity (%PA) during the COVID-19 confinement, an anonymous online survey was launched to be completed by Portuguese families with children. Study Design: A Cross-sectional study design using an anonymous online survey that was launched to assess how Portuguese families with children under 13 years of age adjusted their daily routines to this situation. Methods: Separate ANOVAs were performed to investigate how factors, such as the number of children, age, sex, the housing characteristics, and the adults’ job situation, can affect the percentage of time for physical activity (%PA). Results: Findings, based on data from 2159 children, indicate that: I) Boys and girls did not differ in the %PA on any of the age groups; II) Children with an outdoor space and who had other children in the household were significantly more active (p<.001); III) Children from families with all adults working from home showed lower levels of %PA; IV) Being younger, having a big outdoor space, having other children in the household, and having at least one adult free from working from home, were significant positive predictors of children’s %PA, explaining 21% of the overall variance. Conclusion: Time allocated for PA during this period is reduced compared to what is usually reported on normal days. It is necessary to find strategies to increase children's PA, especially in families where both parents are working and have no outdoor space.

CONCENTRATION OF THE SERUM TGF-BETA1 IN HEALTHY ADULT PEOPLE

2014 ◽  
pp. 90-93
Author(s):  
Van Tuan Nguyen ◽  
Tam Vo ◽  
Bui Bao Hoang
Keyword(s):  
Transforming Growth Factor ◽  
Healthy Adult ◽  
Age Groups ◽  
Elevated Serum ◽  
Cross Sectional Study ◽  
Healthy People ◽  
Sectional Study ◽  
Transforming Growth Factor Beta1 ◽  
Cross Sectional ◽  
And Gender

Elevated serum Transforming growth factor-beta1 (TGF-beta1) levels have been linked to tissue fibrosis including chronic kidney disease. Objectives: (1) Investigate serum TGF-beta1 levels in healthy adult people and (2) Examined the relation between serum TGF-beta1 level and gender, age, body mass index (BMI). Method: A cross-sectional study. TGF-beta1 were quantified by ELISA. Results: Levels of serum TGF-beta1 in healthy people were 13,45 ± 7,17 ng/mL mL (0,59 - 33,10 ng/mL). There are no difference of serum TGF-beta1 levels between men and women, between the age groups (<40 years, 40 to < 60 years and ≥ 60 years), between BMI groups < 23 and BMI group ≥ 23. Key words: TGF-beta1, healthy people

Serum Lipid Profile in Diffuse versus Limited Systemic Sclerosis Data from the SASS cohort

2018 ◽  
Vol 69 (2) ◽  
pp. 403-406
Author(s):  
Codrina Ancuta ◽  
Cristina Pomirleanu ◽  
Cristina Iordache ◽  
Magda Ecaterina Antohe ◽  
Rodica Chirieac ◽  
...  
Keyword(s):  
Systemic Sclerosis ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Serum Lipid ◽  
Total Cholesterol Level ◽  
Cross Sectional Study ◽  
Serum Lipid Profile ◽  
Serum Triglycerides ◽  
Cross Sectional ◽  
Topoisomerase 1

Data about lipoprotein changes and their link with cardiovascular disease and atherosclerosis in systemic sclerosis (SSc) are still challenging. We aimed to evaluate serum lipid profile of patients with SSc and to identify potential relation with different disease specific characteristics (clinical, serological, inflammatory tests) in a cross-sectional study. Standard assessments comprised SSc-related parameters (disease subtype, clinical spectrum, immunological tests) and lipid metabolism (total cholesterol and fractions, triglycerides). Impaired lipid profile (low serum HDL- and high LDL-cholesterol, increased serum triglycerides, slightly modification in total cholesterol level) significantly correlated with diffuse SSc, activity (EUSTAR) and severity (MEDSGER), as well as seropositivity for specific antibodies (anti-centromere and anti-topoisomerase 1). The dyslipidemic profile might represent a pathobiological pathway for atherosclerosis in SSc.

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