scholarly journals Correlation of clinical and laboratory parameters of acute glomerulonephritis in children

2019 ◽  
Vol 6 (2) ◽  
pp. 398
Author(s):  
Chandra Sekhar Kondapalli ◽  
Kalyan Chakravarthy Gondi ◽  
Faisal Mohammed

Background: The present study was conducted to study the clinical and laboratory parameters of acute glomerulonephritis in children admitted in the department of Pediatrics, Katuri Medical College and Hospital, Guntur.Methods: A prospective study was done at Katuri Medical College and Hospital in all children who are clinically diagnosed edema, oliguria, Cola coloured urine and hypertension. Children presenting with Oliguria, Oedema, Haematuria, Hypertension, Pharyngitis or skin lesions were included, both genders male and female. 50 cases of post-streptococcal glomerulonephritis were evaluated by taking detailed history, thorough clinical examination and appropriate investigation were done for establishment of diagnosis. Lab investigations, CUE, RFT, ASO titres, Serum Complement were done. All the statistical analysis was performed by using EPI INFO 3.5-1. The results were expressed as percentages. Test of significance was done by chi square test. P<0.05 was considered significant.Results: 4156 cases were admitted, out of which 50 cases were having acute glomerulonephritis comprising of 1.2%. The incidence of glomerulonephritis was more from July to December. The sex ratio from male to female is 1.17:1. The incidence of glomerulonephritis was more in children coming from low socio-economic families. Signs wise analysis of glomerulonephritis, it was observed that puffiness of face, edema feet and hypertension were the common features. Incidence of hyper tension were more in male children than female children. The incidence of edema and proteinuria are the commonest clinical presentation. The comparison between incidence of oliguria and blood urea is statistically significant. 1/4th of patients of oliguria are associated with increase serum creatinine level.Conclusions: Acute glomerulonephritis is completely a preventable and completely curable disease if proper precaution is like personal hygiene is observed. Proper knowledge of pathophysiology of glomerulonephritis is important for proper management, institution on appropriate treatment and careful follow up of cases are the corner stones for successful outcome of patients.

1970 ◽  
Vol 4 (2) ◽  
pp. 58-63
Author(s):  
Raghuveer Choudhary ◽  
Puja Dullo ◽  
RV Tandon ◽  
Usha Gupta

Background: To enhance successful communication medical teachers are increasingly using different visual aids. Objective: To determine medical students perception of different visual aids like black board (BB), over head projector transparencies (OHPT) and, LCD and to generate recommendations for their optimal use. Methods: A questionnaire based study was carried out among first year MBBS students of Government Medical College, Kota, India. The survey was undertaken among 84 Medical students of first year MBBS of batch 2008 after exposing them to different visual aids like BB, OHPT and LCD in Physiology lectures. A few lectures were absolutely on BB, and some were on OHPT and on LCD. Few classes were taken with mixed visual aids. Students were exposed for such visual aids for one year and then they were requested to complete a questionnaire. Data were statistically analyzed by One Sample Chi-square test. Results: 55 (65.48%) students rated chalk & black board as best visual aids in understanding the topic better as compared to OHPT and LCD (P<0.01). 47 (55.95%) students have good learning experience with black board teaching and it is best mode to note down important points. 56 (66.66%) students favored LCD as more interesting and interactive visual aids (P<0.01). It also complete the lecture faster which was advantageous for 69 (82.17%) students. 77 (91.66%) students wanted mixing of different visual aids (P<0.01). Mostly (75%) do not find any difficulty in switching from one mode to another. No significant gender difference was observed. Conclusion: To improve students learning medical teachers should match the lectures with preferred visual aids. It will maintain interest and enthusiasm among pupil. Key Words: Black board, Teaching, Overhead projector, LCD projector. DOI: 10.3329/jbsp.v4i2.4174 J Bangladesh Soc Physiol. 2009 Dec;4(2): 58-63  


2019 ◽  
Vol 48 (1) ◽  
pp. 13-17
Author(s):  
Mohammad Akteruzzaman ◽  
Shanjoy Kumar Paul ◽  
Shaman Parveen ◽  
Nihar Ranjan Sarker ◽  
Shafi Ahmed ◽  
...  

Acute post streptococcal glomerulonephritis (APSGN) is the most common type of acute glomerulonephritis (AGN) in childhood. It has not been studied well in Bangladesh. To evaluate the clinical characteristics, complications and outcome of Acute post streptococcal glomerulonephritis (AGN). the department of Pediatric Nephrology at Sir Salimullah Medical College and Mitford Hospital, Dhaka. A prospective study from April 2011 to March 2012 were conducted among the patients diagnosed as AGN in outdoor and indoor department. Hospital records of all 34 children who had been admitted to Sir Salimullah Medical College and Mitford Hospital were reviewed. All demographic, clinical, paraclinical data and consumed medications were obtained. Among 34 cases female and male ratio were 2.4:1; mean age of was 8.76 yrs. ± 2.5 SD and peak age 7.6. Etiology of AGN was post infectious glomerulonephritis (PIGN) 85.3%, ASO titer was raised in 88.2%, 41.2% had raised blood urea, and 32.4%raised serum creatinine level. All children presented with microscopic hematuria (100%), hypertension (100%), and edema (100%), other findings are fever (55.9%), oliguria (94.1%), abdominal pain (52.9%). History of sore throat and pyoderma was present in 41.2% and 44.1% cases respectively. Complications like hypertensive encephalopathy three (8.8%), urinary tract infection (UTI) one (2.9%) total seven (20%) were heart failure two (5.9%) and Acute kidney injury (AKI) one (2.9%), total seven (20%) were expired. Majority of cases manifest typically with edema, oliguria and hematuria. It usually has an uneventful course. Bangladesh Med J. 2019 Jan; 48 (1): 13-17


Author(s):  
Dur-e- Nishat

Background: Family medicine is a field in which complete and detailed set of healthcare services are provided to the patients and their families. In developed countries, freshly graduated students choose family medicine as a priority for their career. However, in Pakistan it is not the case. The present study is undertaken to determine the perceptions of final year medical students’ about Family Medicine as a viable career. Methods: A total number of 504 students participated in the study. This was a cross-sectional study. The study participants were in their final year of medical college. Data was collected using a preapproved questionnaire. Data was entered and analyzed via SPSS version 17 and Chi-Square test was used post-stratification. Results: Only 14.3% (n=72) medical students had heard about Family Medicine. Only 18% (n=92) would select family medicine as a profession. The most frequent rationale for choosing the field of Family Medicine was the variety of patients seen in general practice (55.4% n=51). Conclusion: There is a dire need to focus on increasing awareness about the field of family medicine among medical students. The students should be counseled on the advantages along with the disadvantages of choosing this field as a medical profession.


2021 ◽  
pp. 63-66
Author(s):  
Wasif Mohammad Ali ◽  
Nazia Nanen ◽  
Atia Zaka Ur Rab ◽  
Syed Amjad Ali Rizvi ◽  
Mehtab Ahmad

Introduction: Laparoscopic cholecystectomy has become procedure of choice for treatment of symptomatic gallstone [1] disease . Even though it is a safe procedure occasionally it can be difcult and requires conversion to open cholecystectomy for various problems faced during surgery. Preoperative prediction of difcult laparoscopic cholecystectomy and likelihood of conversion to open cholecystectomy will avoid such complications and overall cost of treatment. Aim: To evaluate the clinico-radiological factors predicting difcult laparoscopic cholecystectomy Methods: This was a prospective study conducted from October 2018 to November 2020. Total of 101 patients meeting inclusion criteria undergoing laparoscopic cholecystectomy were included in the study. Various clinical, radiological and biochemical parameters and intraoperative difculties during surgery were recorded. The statistical analysis was done using chi-square test and ANOVA test. Results: The parameters such as sex, age, duration of disease, co-morbid disease, previous history of cholecystitis, palpable gall bladder, BMI, TLC, thickness of gall bladder, largest stone size and impacted stone are found statistically signicant in predicting difcult laparoscopic cholecystectomy and conversion to open cholecystectomy preoperatively. Conclusion: Difcult laparoscopic cholecystectomy may be predicted preoperatively even with a good clinical judgement whereas both clinical and radiological parameters provide a better preoperative prediction of difcult cholecystectomy so that the surgeon can prepared in advance for the complications.


2017 ◽  
Vol 9 (2) ◽  
pp. 47-51 ◽  
Author(s):  
Nisha Shrestha ◽  
P Shrestha

Background: Pressure ulcer (PU) development remains a significant complication among at-risk patients. It is considered “never events” because they are preventable and should “never” happen. It has been associated with increased morbidity, mortality, hospital cost and length of stay in the hospital. Prevention of pressure ulcers is considered a nurse-sensitive indicator hence nurses should have adequate knowledge about current evidence-based prevention and management of pressure ulcer. However, non adherence to these guidelines is frequent and lack of knowledge may act as barriers to using guidelines in clinical practice.Objectives: The objectives of the study were to 1. assess the knowledge of pressure ulcer management among nurses 2. determine the level of knowledge of pressure ulcer management among nurses 3. assess the association of knowledge of nurses and baseline variables.Methods: A descriptive cross sectional study was conducted, using pretested self administered questionnaire to assess the knowledge on pressure ulcer management among purposively selected 100 nurses working in Gandaki Medical College Teaching Hospital in 2015. Descriptive statistics as frequency and percentage were used and inferential statistics (Chi-square test) was done to find out association between knowledge and selected baseline variables.Results: The study revealed that 59% of the respondents had adequate knowledge where as 41% of nurse’s knowledge was found to be inadequate. Significant association was not found between age, working ward, experience, education, training, duration and knowledge of pressure ulcer management among Nurses.Conclusion: This result indicates that more than half of the nurses had the adequate knowledge but there is still need of education and training related pressure ulcer management.Journal of Gandaki Medical CollegeVolume, 09, Number 2, July December  2016, Page: 47-51


2009 ◽  
Vol 49 (6) ◽  
pp. 322
Author(s):  
Suryadi Nicolaas Napoleon Tatura ◽  
Novie Homenta Rampengan ◽  
Jose Meky Mandei ◽  
Ari Lukas Runtunuwu ◽  
Max FJ Mantik ◽  
...  

Background Dengue shock syndrome (DSS) is characterized bysevere vascular leakage and hemostasis disorder. It is the cause of death in 1 to 5 percent of cases. WH 0 management guidelines for resuscitation remain empirical rather than evidence-based.Objective To find out the alternative fluids to replace plasmaleakage in DSS.Methods We performed a prospective study and randomizedcomparison of plasma and gelatin solution for resuscitation ofIndonesian children with DSS. We randomly assigned 25 subjectswith DSS to receive plasma and 25 children to receive gelatinfluid. Statistical analyse were performed using chi-square test,Fisher's exact test, t test, Mann-Whitney test.Results The increment of pulse pressure width and the decrement of hematocrit in subjects treated with gelatin were higher than that of plasma atfour-hour therapy (P=0.002 and P=0.017). Only one patient died caused by unusually manifestation of DSS. The increment of body temperature in subjects treated with plasma was higher than that of gelatin at four-hour therapy (P=O.Oll). The decrement of platelet count in subjects treated with gelatin were less than that of plasma (P=0.018). The increment of diuresis rate in subjects treated with gelatin was higher than that of plasma at twenty-hour therapy (P<O.OOOl). The decrement of respiratory rate in subjects treated with gelatin was higher than that of plasmaat twenty-eight hour therapy (P=0.018). There was no differencein studied variables : total volume rate, blood pressure, pulse rate, re-shock rate, clinical fluid overload, allergy reactions, bleeding manifestations, and length of stay (P>0.05).Conclusions Gelatin solution can be used as volume replacementin resuscitation of DSS if blood plasma is not available especiallyat four-hour therapy.


Author(s):  
Jamsheera Cp ◽  
Ethel Suman

Objective: The present study aimed at finding the resistance pattern of Pseudomonas aeruginosa and other Pseudomonas species isolated from various clinical specimens in the laboratory.Methods: A total of 150 isolates of different species of Pseudomonas obtained from various clinical specimens processed at the Microbiology laboratory of Kasturba Medical College, Manipal Academy of Higher Education, were taken for this study. Antibiotic susceptibility testing was performed by Kirby-Bauer disc diffusion method and interpreted according to the CLSI guidelines. Biofilm assay was performed by modified O’Toole and Kolter method. The results were analyzed using SPSS 17.0 and Student’s unpaired t-test, Kruskal–Wallis, Mann–Whitney, ANOVA, and Chi-square test. p<0.05 was considered statistically significant.Results: Increased resistance was observed by P. aeruginosa to cefotaxime, cotrimoxazole, levofloxacin, ofloxacin, and ticarcillin clavulanate. There was also a good correlation between antibiotic resistance to aztreonam, netilmicin, and ceftazidime and biofilm production. Results of the present study, therefore, demonstrated the occurrence of resistance to various antipseudomonal agents among the biofilm-producing P. aeruginosa isolates.Conclusion: The present study may help in assessing the seriousness of drug resistance caused by biofilm formation in P. aeruginosa and devise strategies through antibiotic policies to minimize such problems.


2020 ◽  
Vol 15 (1) ◽  
pp. 6-9
Author(s):  
Irmayani

Diare adalah pengeluaran kotoran (tinja) dengan frekuensi yang meningkat (tiga kali dalam 24 jam) disertai dengan perubahan konsistensi tinja menjadi lembek atau cair, dengan atau tanpa darah/lendir dalam tinja.(Wijoyo, yosef 2013). Penelitian ini bertujuan untuk mengetahui hubungan kebiasaan jajan dengan terjadinya penyakit diare pada anak di SD Inpres Amaro Kabupaten barru. Penelitian ini dilakukan dengan menggunakan jenis penelitian Analitik Correlative dengan desain Cross Sectional Study, populasi dalam penelitian ini adalah siswa yang ada di SD Inpres Amaro Kabupaten Barru sebanyak 109 orang. Pengambilan sampel menggunakan teknik purposive sampling, didapatkan 51 responden sesuai dengan kriteria inklusi. Pengumpulan data dilakukan dengan menggunakan kuesioner. analisa data mencakup analisis univariat dengan mencari distribusi frekuensi, analisis bivariat menggunakan uji Chi- Square Test dengan interval kemaknaan α 0,05. Dari hasil analisis bivariat pada kebiasaan jajan didapat nilai ρ = 0,004 dan personal hygiene didapat nilai ρ = 0,008. Kesimpulan dalam penelitian ini adalah terdapat hubungan antara kebiasaan jajan dengan terjadinya penyakit diare pada anak di SD Inpres Amaro Kabupaten Barru


2021 ◽  
Vol 4 (1) ◽  
pp. 90-101
Author(s):  
Sumantri Alikhan Sains

Based on data from the Tikep Health Center, for the last three years Waturempe Village has become the village with the highest incidence of skin diseases and accounts for almost 50% of skin diseases. The aim of this study was to determine the relationship between personal hygiene and environmental conditions in Waturempe Village. The population in this study were all heads who live in Waturempe Village as many as 120 heads of families (KK). The sample size was 92 respondents, taken by simple random sampling. The data were obtained using a questionnaire then analyzed descriptively and inferentially using the chi square test. The results showed that there was a strong relationship between personal hygiene (X²hit=39,21 2> X²tab = 3,841), moisture (X²hit=36,655 > X²tab=3,841), temperature (X²hit=45,126 > X²tab=3,841), natural lighting (X²hit=29,362> X²tab=3,841), and occupancy density (X²hit=27,273 > X²tab=3,841) with complaints of skin diseases. There was a moderate relationship between water quality and complaints of skin diseases (X²hit=19,354 > X²tab=3,841). It is expected that the community always maintains personal hygiene and improves condition of the home environment and is always aware of the transmission of skin diseases.


2020 ◽  
pp. 9-11
Author(s):  
Madhu Kumari ◽  
Kumari Bibha ◽  
Abha Sinha ◽  
Debarshi Jana

Objective: The objective of this study is to find out association between scar thickness, assessed sonographically, and intraoperative findings (IOF). Study Design: Descriptive study. Place and Duration of Study: Department of Obstetrics and Gynecology, Sri Krishna Medical College and Hospital, Muzaffarpur, Bihar from June 2019 to May 2020. Methodology: A total of 70 pregnant patients were included in this study. Transabdominal ultrasound was done for scarred uteri. Sonographic findings were co-related with introperative findings. All the given data were entered on SPSS version 23. Age was expressed as mean ± SD. Parity, gestational age, and interval between cesarean sections were expressed as frequencies with percentages. Statistical analysis was done by using Chi-square test for categorical data for association between sonographic scar thickness and intraoperative findings. The statistical significance was set at p-value <0.05. Results: The age range of the patients was 20- 36 years with a mean of 27.91 ±3.690 years. Gestational age at the time of cesarean section was between 27-40 weeks of gestation with a mean of 37 ±2.126 weeks. The interval from previous cesarean was 10 months at the minimum, and 6 years at the maximum with a mean of 2.29 ±1.0 months. Mean scar thickness was 2.5 mm. Association between scar thickness (<1-3 mm) and intaoperative findings of dehiscence and rupture showed a p-value of <0.001. Conclusion: Sonographic assessment of a uterine scar has a practical application to determine the thickness of previous scar, and assess its integrity.


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