scholarly journals Dyslipidaemia pattern amongst diabetic patients visiting a tertiary care hospital in Eastern Odisha

2017 ◽  
Vol 4 (6) ◽  
pp. 1662
Author(s):  
Surendra Nath Behera ◽  
Shubhransu Patro

Background: With controlled blood sugar levels, the occurrence of dyslipidaemia can be reduced. Due to poor awareness and literacy being a major concern, there is an association in the incidence of dyslipidaemia and cardiovascular risk. Routine and timely observations can help health care professionals to reduce the future risk.Methods: The current study was initiated at the Department of Medicine, KIMS, Bhubaneswar (Odisha). It included in total 669 patients, who were assigned into two groups: Group 1(Diabetic) included 364 patients and Group 2 (Non-diabetic) included 305 patients. The study patients were screened using a pretested structured questionnaire. The plan and checklist were linked by unique identification code (ID). Data was gathered in a friendly atmosphere after obtaining informed consent.Results: In the current study, all characteristics of diabetes were correlated with each parameter and it was found that disproportionate body mass index, high waist girth was correlated with incidence of cardiovascular disease (CVD). Literacy is one of the factor found intermediate responsible for CVD. The more educated, the more advances in current lifestyle is observed whereas due to illiteracy, awareness about health issues is less and both together result in increased incidence of CVD.Conclusions: Dyslipidaemia should be promptly diagnosed and treated aggressively to reduce the rate of morbidity and mortality in diabetic patients.

2021 ◽  
Vol 12 (5) ◽  
pp. 101-106
Author(s):  
Brijesh Mukherjee ◽  
Monalisa Mohanty

Background: Diabetic atherosclerosis is a heterogeneous condition, and that dyslipidemia is only one aspect of the pathophysiology. However, dyslipidemia is the most readily measured and, at the present time, the most readily treated aspect of the problem. The occurrence of dyslipidemia can be reduced by good glycemic control. However poor awareness and other socio-economic factors is a major concern and pose a major hindrance in controlling blood sugar levels. Aims and Objective: This study was conducted to study the dyslipidemia pattern in diabetic patients and its association with other factors. Materials and Methods: The study included 500 subjects and was divided into two groups: Group 1(Diabetic) included 276 patients and Group 2 (Non-diabetic) included 224 patients. The study patients were screened using a pretested structured questionnaire. Fasting plasma glucose and serum lipid profile (cholesterol, TG, HDL) were estimated in automated analyzer (Erba Manheim EM 200). Results: In the current study, all characteristics of diabetes were correlated with each parameter and it was found that disproportionate body mass index, high waist girth was correlated with incidence of dyslipidemia. The education levels and financial background of the subjects were also studied and it was found to correlate well with diabetic dyslipidemia. Conclusion: Early diagnosis and treatment of dyslipidemia in diabetic patients can reduce the morbidity and mortality due to the disease.


2021 ◽  
Vol 12 (02) ◽  
pp. 281-289
Author(s):  
Pranjal Phukan ◽  
Kalyan Sarma ◽  
Barun Kumar Sharma ◽  
Deb K. Boruah ◽  
Bidyut Bikash Gogoi ◽  
...  

Abstract Objective Japanese encephalitis (JE) is an arthropod-borne flavivirus infection having high mortality and morbidity. This study was performed to evaluate the conventional magnetic resonance imaging (MRI) findings in JE and to find out any difference between pediatric and adult JE. Materials and Methods This retrospective study was performed on serologically positive 54 JE patients presented to a tertiary care hospital with acute encephalitic symptoms between April 2016 and October 2019. Relevant neurological examination, cerebrospinal fluid analysis, and MRI scan of the brain were performed. Results Fifty-four JE patients (n = 31 males and n = 23 females) having 32 pediatric and 22 adult JE were included in the study sample. Group 1 JE (n = 16) patients had encephalitic symptoms with duration less than 15 days up to the day of MRI scan and group 2 JE (n = 38) had symptoms more than 15 days. Group 1 JE had mean apparent diffusion coefficient (ADC) value of 0.563 ± 0.109 (standard deviation [SD]) × 10–3 mm2/sec and group 2 JE had 1.095 ± 0.206 (SD) × 10–3 mm2/sec. The mean ADC value of pediatric JE was 0.907 ± 0.336 (SD) × 10–3 mm2/sec and adult JE was 0.982 ± 0.253 (SD) × 10–3 mm2/sec. Conclusion The majority of the JE patient shows abnormal signal alterations in bilateral thalami and substantia nigra. Diffusion-weighted imaging with ADC mapping helps in evaluating the stage of the JE. No statistical significance of the various conventional MRI findings was found between the pediatric JE and adult JE.


2017 ◽  
Vol 36 (3) ◽  
pp. 250-255 ◽  
Author(s):  
Dillip Kumar Dash ◽  
Mrutunjaya Dash ◽  
M.D. Mohanty ◽  
Naresh Acharya

Introduction: Administration of S. boulardii in addition to rehydration therapy in diarrhea found to be beneficial in many aspects owing to a variety of causes and importantly it is was not associated with any adverse effects.Material and Methods: We conducted a prospective study of children suffering from acute diarrhoea, at a private tertiary care hospital. Children were divided into 2 groups randomly as per odd(Group 1 ) and even (Group 2) bed allotted in indoor at the time of admission: Group 1 included children on oral rehydration therapy (ORT) + Zinc + Saccharomyces boulardii (Probiotic 5 billion CFU twice daily) and Group 2 comprised of children on ORT+ Zinc. Our objective was to systematically review data on the effect of S. boulardii on acute childhood diarrhoea.Results: Out of a total of 126 children less than 2 years, 2-6 years and 6-14 years were 72 (57.14%), 42(33.33%) and 12(09.52%) respectively. The duration of diarrhoea in Group 1 was 26.31 hours and Group 2 was 47.81 hours (p<0.01). The frequency of diarrhoea showed improvement within 24 and 72 hours in Group 1 and Group 2 respectively (p<0.01).Similarly, the mean duration of hospital stay was 2.68 days in Group 1 and 4.8 days in Group 2.The treatment cost was INR 850 and INR 1650 while social cost was INR 1250 and 2600 in Group 1 and 2 respectively.Conclusion:This study shows that S. boulardii reduced the duration, frequency and hospital stay of diarrhoea thereby reducing the treatment and social costs.J Nepal Paediatr Soc 2016;36(3):250-255


2021 ◽  
Vol 10 (02) ◽  
pp. 124-128
Author(s):  
Muhammad Sajid Abbas Jaffri ◽  
Saja Riyaz ◽  
Sara Riyaz ◽  
Mah Rida

Objective: To compare the knowledge and practices of diabetes self- care management among type 2 diabetic patients in two hospitals of Karachi. Study Design and Setting: A cross sectional study was carried out at two Tertiary Care Hospital of Karachi from March 2018 to August 2018. Methodology: A total of 120 subjects of type 2 diabetes were included in the study. Data was collected through structured questionnaire. Knowledge regarding diabetes includes normal blood sugar level, symptoms of low and high blood sugar and management of these symptoms. Structured questionnaire was used to collect information of sociodemographic characteristics, knowledge and attitude of diabetes and self-care management practices. Data was analyzed by SPSS version 21. P value less than 0.05 considered as significant Results: Majority of the participants were females (55%) and males were (45%).The duration of diabetes in majority of participants, (43.3%) was less than 5 years. From total 53.3% of our study participants were aware about the knowledge of diabetic complications. Approximately ,59.6% participants thought visit to eye specialist is important and about 44.16% thought that monthly visit to hospital for general health is important for diabetic patients. When asked about early signs of development of complications 48.3% participants thought that development of foot ulcers ,83% thought diabetes was strongly associated with obesity. Total, 76.6% participants thought that plan of meal is important. Total, 30.83% participants were in agreement with this thought that diabetes was strongly associated with obesity. Conclusion: The knowledge of self-care practices in diabetic patients was average in this study


JMS SKIMS ◽  
2017 ◽  
Vol 20 (2) ◽  
pp. 96-100 ◽  
Author(s):  
Mushtaq Ahmad Sheikh ◽  
Altaf Ahmad Bhat ◽  
Rukaya Akhthar ◽  
Mudassir Ahad Wani ◽  
Tariq Wani

Objectives: This study was done to evaluate the frequency and severity of nasal trauma secondary to nasal continuous positive airway pressure (NCPAP) in neonates and different methods to reduce the nasal septum injury via CPAP Methods: This is a prospective study carried out in the Neonatal Care Unit (NCU) of LAL DED maternity hospital associated with department of pediatrics Government Medical College, Srinagar, Kashmir. The study included newborns that underwent NCPAP with prongs on admission and those receiving NCPAP after weaning from ventilator, from 1st January 2016  - 1st jan 2017. Neonates noses were monitored from the first day of NCPAP treatment until its weaning. Nasal trauma was reported into Three Grades: (I) Erythema/pressure indentation (II) superficial Erosion and (III) Septal necrosis. Results:-258 newborns were included in study, 136 males and 122 females. All enrolled newborn received CPAP. Babies were randomly allocated to different groups in which no barrier and different barriers were applied. Randomization ofgroup of infants who received no barrier(group 0) and different barriers( group 1,2,&amp;3) was done by systematic allocation, in which first newborn was randomly designated to no barrier group 0 on particular day of admission ,and subsequently alternating with other three groups i.e group 1,group 2, group 3. The mean gestational age, birth weight and CPAP days in each group is 31wk (GA28-35 wks),1200 gms(0.7kg-1.8kg) &amp; 5 days(3-10days) respectively. Incidence of Septal  necrosis was 26.7% in the babies that had ‘No barrier applied at septal hudson prongs interface (Group0), which was significantly more (p&lt;0.001) when compared with other three groups, within which its incidence was 2.8% in Cotton applied at septal and hudson prongs interface with glycerine (Group1), 7.1% in Danaplast applied at interface(Group2) and 0.0% in Cotton soaked with normal saline(Group3) respectively. In Group 0 nasal septal injury Grade 1 is (35%),grade 2 (35%),and grade 3(30.0%), in Group 1, grade 1 septal injury is (84%), grade 2(12.7%) &amp; grade 3(2.8%),In Group 2 grade 1 is (65.7%),grade2(30.0%),grade3 (4.3%) and Group3 grade1(80.7%),grade2(19.3%) and Grade3 (0.0%) Conclusions: Nasal trauma is a frequent complication of NCPAP, especially in preterm babies and babies requiring nasal prongs for longer duration. And can be prevented by applying a barrier as in group 1,2 &amp;3 in our study shows statistically significant decreased in severe nasal septal injury. JMS 2017;20(2):96-100  


2015 ◽  
Vol 48 (01) ◽  
pp. 048-053
Author(s):  
Mushtaq Mir ◽  
Shabir Ahmad Mir ◽  
Muddassir Shahdhar ◽  
Mumtazdin Wani ◽  
Hakim Adil Moheen ◽  
...  

ABSTRACT Background: There is no single, universally applicable technique for hypospadias repair and numerous techniques have been practised from time to time. We compare the results of our new technique (Mirs’ technique also called Mush & Shab’s technique) to Snodgross urethroplasty. Mirs’ technique is a modified version of Thiersch-Duplay urethroplasty. Material and Methods: This prospective comparative study was carried out in a tertiary care hospital of Northern India over a period of 3 years from March 2010 to March 2013 and included 120 patients of anterior (distal penile, subcoronal, coronal and glanular) hypospadias without chordee. They underwent either Mirs’ technique (group 1 n = 60) or Snodgrass technique (group 2 n = 60). Follow-up was at 1-week, 1-month, 3 months and 6 months. Results: The mean operative time was 55 min (range: 43-70 min) in group 1 and 71.9 min (range: 60-81 min) in group 2 (P & 0.001). Urethrocutaneous fistula developed in two and four patients in group 1 and 2, respectively. Fistula closure was done at least 3 months postoperatively, and there was no significant difference in success rate between the two groups. Three cases of glanular dehiscence were detected (one in group 1 and two in group 2); the patient from group 1 had a successful repair using the already preserved prepuce. Conclusion: Mirs’ modification of Thiersch-Duplay technique for distal hypospadias is a time saving procedure with a lower overall complication rate. Valuable local tissue is preserved to deal with any complication that may occur. Analgesic requirement was significantly lower in this minimally traumatic technique. As it is less time consuming, simple and easy to learn with a short learning curve, this technique deserves application in cases of distal hypospadias.


2017 ◽  
Vol 10 (2) ◽  
pp. 49-52 ◽  
Author(s):  
Manash Kumar Goswami ◽  
F. Hossain ◽  
A.B. Shamsudduha ◽  
M Asaduzzaman

Background and objectives: Recurrent pterygium is an important ocular problem in our country. There are different modalities of treatment for recurrent pterygium. The present study was undertaken to determine the effect of intraoperative mitomycin C along with conjunctival auto graft to prevent recurrence of pterygium.Methods: Patients with recurrent pterygium attending a tertiary care hospital in Dhaka from January 2013 to June 2015 were included in the study. Cases were randomized into two groups. Group 1 had pterygium surgery with conjunctival auto graft and Group 2 had auto graft and intraoperative mitomycin C (0.02%). All cases were followed up for one year to assess recurrence of pterygium.Results: A total of 54 recurrent pterygia cases were included in the study. The age of study population was 25 to 65 years. The recurrence rate of pterygium after 12 months was 77.7% in group 1 and none in group 2. No major postoperative complication was observed.Conclusion: The study demonstrated that the use of intraoperative mitomycin C along with conjunctival auto graft had significant effect in preventing the recurrence of pterygium.IMC J Med Sci 2016; 10(2): 49-52


Author(s):  
G. Muthu Kavitha ◽  
M. Shanthi ◽  
M. S. Ahil

Background: The objective of the present study was to compare the efficacy of terbinafine and griseofulvin in patients with tinea corporis in a tertiary care hospital, Madurai.Methods: About 60 patients are selected from the outpatient department of Dermatology according to inclusion and exclusion criteria. They were divided into 2 groups of 30 patients each. Group 1 received tab. terbinafine 250 mg OD and group 2 received 250 mg BD for 4 weeks. All patients were investigated at baseline, end of 2nd week and at end of 4 weeks. Effectiveness of both the drugs were determined by achieving clinical as well as mycological cure. The results were recorded, tabulated and analysed using student’s t test.Results: Patients in group 1 showed higher clinical and mycological cure rate when compared with group 2.Conclusions: Oral terbinafine is the effective antifungal agent in the treatment of extensive tinea corporis infection.


2016 ◽  
Vol 4 (1) ◽  
pp. 24
Author(s):  
Upendra Pandit ◽  
Chittaranjan Das ◽  
Farhat Banu ◽  
Shakil Ahamad

Introduction: Magnesium sulphate (MgSO4) is an effective and safe drug which stabilizes the patient within few hours of eclampsia and terminates subsequent seizures if it is given on time. The aim of this study was to compare maternal and fetal outcome between a group of eclamptic mothers who came to the tertiary care hospital directly without receiving MgSO4 (Group 1) and those referred from primary care centers after receiving loading dose of MgSO4 (Group 2).   Methods: This is a retrospective cohort study of eclamptic mothers who were admitted and managed from the period of 1st January 2012 to 31st March 2016 at Nepalgunj Medical College Teaching Hospital, Nepal. Sociodemographic characters and maternal and fetal outcome was compared between the two groups.   Results: Among 92 cases, 57 (62%) were from Group 1 and 35 (38%) were from Group 2. Most of the mothers attended from Banke district (n=52, 56.5%) followed by Bardia district (n=17, 18.5%). Brahmin and Chhetri were 20 (35%) and 10 (29%); Muslim 16 (28%) and 4(11%); Janajati from Terai 16 (28%) and 8 (23%); Janajati from hilly region 4 (7%) and 5 (14%); and Chaudhari 1 (2%) and 8 (23%) in Group 1 and Group 2 respectively.  More (n=26, 74%) mothers had baby with good Apgar score in Group 2 than in Group 1 (n=33, 58%). There were 14 (15.2%) still births; 9 (16%) in Group 1 and 5 (14%) in Group 2. Complication rate was observed more in Group 1 (n=16, 28%) than in Group 2 (n=7, 20%) and the most common complication in both groups was wound infection. The mean days of hospital stay was 5.96 (SD=3.32) and 5.91 (SD=3.38) in Group 1 and Group 2 respectively.   Conclusion: The group receiving magnesium sulphate in primary care centre have good fetal outcome and less maternal complications compared to those who were admitted directly in tertiary care centre and receive the treatment there.


Author(s):  
Zeenat Fatima ◽  
Rakesh Chandra Chaurasia ◽  
Satya Prakash Singh

Background: Dry eye disease (DED) is the very common and underdiagnosed ocular condition affecting vision, quality of life, and the outcomes of cataract or refractive surgery. Dry eye disease (DED), either alone or in combination with other conditions, is a frequent cause of ocular irritation that leads the patients to seek ophthalmic care. Due to a wide variety of presenting symptoms, it is often unrecognized and this causes great frustration of the patient and treating physician. While these symptoms often improve with appropriate treatment, usually in majority of the cases the disease may not be curable. Aim of the study was to compare the efficacy of tacrolimus and cyclosporine in dry eye disease.Methods: This was a single centred, 3 months prospective study. Patients with unilateral or bilateral dry eye disease and an ocular surface disease index score >12, atleast one eye with schirmer score <5mm and TBUT <10 s were enrolled in the study. The enrolled patients were randomly divided into two groups, twenty-five patients in Group 1 and twenty three patients in Group 2 completed the follow up. Group 1(n =25) who received 0.03% tacrolimus eye ointment twice daily for consecutive 3 months and Group 2 (n= 23) received 0.05% cyclosporine eye drops twice daily for consecutive 3 months the primary efficacy outcome was Schirmer score after 3 months. The secondary outcomes were TBUT and adverse effects.Results: After 3 months, both the treatment groups showed significant improvement in mean Schirmer score (p<0.001) and mean TBUT (p <0.0001). However, on comparing both the groups, mean Schirmer score and mean TBUT, results were comparable. No patient discontinued treatment because of minor ocular adverse effects.Conclusions: Dry eye patients demonstrated improvement in Schirmer score and TBUT after 3 months of treatment with tacrolimus 0.03% ointment and cyclosporine 0.05% eye drops.


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