scholarly journals Role of yoga therapy on lipid profile in patients of hypertension and prehypertension

2018 ◽  
Vol 5 (2) ◽  
pp. 321
Author(s):  
Nalin Kumar Mahesh ◽  
Anil Kumar ◽  
Keshavamurthy Ganapathy Bhat ◽  
Niket Verma
Keyword(s):  
Serum Lipid ◽  
Therapy Group ◽  
Blood Lipid ◽  
Control Group ◽  
Lipid Levels ◽  
Art Of Living ◽  
Yoga Therapy ◽  
Yoga Group ◽  
Training Protocol

Background: Hypertension and dyslipidemia are one of the most prevalent cardiovascular disorders affecting 20% of world’s population. There is emerging data that yoga therapies may be useful in managing modest elevations in BP. Yoga, specific yogic exercise (Sudarshan kriya) taught as a training protocol under Art of living course (AOL), is especially attractive as a candidate therapy in the management of elevated BP because of its combination of gentle physical activity. Hence, this study was undertaken to compare the effects of SDK on blood lipid levels.Methods: A total of 300 patients of hypertension and prehypertension were taken in the study where control group were given drugs treatment and life style modification and yoga group additionally had undergone yoga training. Lipid levels were estimated in both groups at entry, 06 months and 12 months and analyzed.Results: Lipid levels at entry were same in both while the yoga therapy group showed decrease in TG, LDL and VLDL at six months and 12 months but decrease was not significant. HDL levels showed significant increase in yoga group (P<0.05) at six months which was maintained at 12 months more so in diabetic patients.Conclusions: Yoga therapy has beneficial effect on serum lipid levels and should be included in therapy along with other measures.

Effects of acupuncture on anthropometric and serum metabolic parameters in premenopausal overweight and obese women: a randomized, patient- and assessor-blind, sham-controlled clinical trial

2020 ◽  
pp. 096452842091225
Author(s):  
Koh-Woon Kim ◽  
Woo-Chul Shin ◽  
Min Sun Choi ◽  
Jae-Heung Cho ◽  
Hi-Joon Park ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Treatment Group ◽  
Serum Lipid ◽  
Sham Acupuncture ◽  
Metabolic Parameters ◽  
Secondary Outcome ◽  
Control Group ◽  
Lipid Levels ◽  
Serum Lipid Levels

Objective: The aim of this study was to examine the effect of acupuncture on obesity-related parameters with regard to metabolomics. Methods: This two-arm parallel, patient- and assessor-blind, sham-controlled randomized clinical trial included 120 obese participants. Participants were randomized into two groups. The treatment group received a combined intervention of manual acupuncture (MA) plus electroacupuncture (EA), while the control group received a combination of sham acupuncture interventions consisting of sham MA plus sham EA for 6 weeks. The serum lipid levels were measured as the primary outcome measure and anthropometric parameters and serum metabolic profiles including amino acids and carnitines were measured as secondary outcome measures. Results: The serum lipid levels and anthropometric measurements did not significantly differ between groups, while body weight, body mass index (BMI), and waist circumference were improved within each group and the level of high-density lipoprotein cholesterol increased over time in the treatment group. There were no significant differences in amino acid levels between groups, while certain carnitine (C2, C4, C6, and l-carnitine) levels were significantly increased ( p < 0.05) in the treatment group compared to the control group. Conclusion: In summary, 6 weeks of acupuncture treatment did not affect anthropometric and serum metabolic parameters, with the exception of certain carnitines, when compared to sham acupuncture. The observation of increased carnitine levels in the acupuncture group could result in potential long-term benefits to obese individuals. Additional studies are needed to investigate the long-term effects of acupuncture on lipid metabolism and the underlying mechanism of action. Trial registration number: This study is registered at ClinicalTrials.gov (NCT02066090).

scholarly journals Cerebrovascular Changes and Neurodegeneration Related to Hyperlipidemia: Characteristics of the Human ApoB-100 Transgenic Mice

2020 ◽  
Vol 26 (13) ◽  
pp. 1486-1494 ◽  
Author(s):  
Melinda E. Tóth ◽  
Brigitta Dukay ◽  
Zsófia Hoyk ◽  
Miklós Sántha
Keyword(s):  
Transgenic Mouse ◽  
Serum Lipid ◽  
Lipoprotein Metabolism ◽  
Transgenic Mouse Models ◽  
Wild Type ◽  
Lipid Levels ◽  
Cerebrovascular Lesions ◽  
Wide Range ◽  
And Function

Serum lipid levels are closely related to the structure and function of blood vessels. Chronic hyperlipidemia may lead to damage in both the cardio- and the cerebrovascular systems. Vascular dysfunctions, including impairments of the blood-brain barrier, are known to be associated with neurodegenerative diseases. A growing number of evidence suggests that cardiovascular risk factors, such as hyperlipidemia, may increase the likelihood of developing dementia. Due to differences in lipoprotein metabolism, wild-type mice are protected against dietinduced hypercholesterolemia, and their serum lipid profile is different from that observed in humans. Therefore, several transgenic mouse models have been established to study the role of different apolipoproteins and their receptors in lipid metabolism, as well as the complications related to pathological lipoprotein levels. This minireview focused on a transgenic mouse model overexpressing an apolipoprotein, the human ApoB-100. We discussed literature data and current advancements on the understanding of ApoB-100 induced cardio- and cerebrovascular lesions in order to demonstrate the involvement of this type of apolipoprotein in a wide range of pathologies, and a link between hyperlipidemia and neurodegeneration.

scholarly journals Effect of SYTL3-SLC22A3 Variants, Their Haplotypes, and G × E Interactions on Serum Lipid Levels and the Risk of Coronary Artery Disease and Ischaemic Stroke

2021 ◽  
Vol 8 ◽  
Author(s):  
Peng-Fei Zheng ◽  
Rui-Xing Yin ◽  
Xiao-Li Cao ◽  
Wu-Xian Chen ◽  
Jin-Zhen Wu ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Serum Lipid ◽  
Blood Lipid ◽  
Lipid Levels ◽  
Chinese Han ◽  
Han Population ◽  
Southern Chinese ◽  
Artery Disease ◽  
Lipid Parameters

Background: The current study aimed to investigate the effects of synaptotagmin-like 3 (SYTL3) and solute carrier family 22 member 3 (SLC22A3) single nucleotide polymorphisms (SNPs) and gene-environment (G × E) interactions on blood lipid levels as well as the risk of coronary artery disease (CAD) and ischaemic stroke (IS) in the Southern Chinese Han population.Methods: The genetic makeup of 6 SYTL3-SLC22A3 SNPs in 2269 unrelated participants (controls, 755; CAD, 758 and IS, 756) of Chinese Han ethnicity was detected by the next-generation sequencing techniques.Results: The allele and genotype frequencies of the SYTL3 rs2129209 and SLC22A3 rs539298 SNPs were significantly different between the case and control groups. The SLC22A3 rs539298 SNP was correlated with total cholesterol (TC) levels in controls, the rs539298G allele carriers maintained lower TC levels than the rs539298G allele non-carriers. At the same time, the SLC22A3 rs539298 SNP interacted with alcohol consumption reduced the risk of CAD and IS. The SYTL3-SLC22A3 A-C-A-A-A-A, G-T-C-G-C-A and A-T-A-A-C-A haplotypes increased and the A-C-A-A-C-G haplotype reduced the risk of CAD, whereas the SYTL3-SLC22A3 A-C-A-A-A-A, G-T-C-G-A-G and A-T-A-A-C-A haplotypes increased and the A-C-A-A-A-G and A-C-A-A-C-G haplotypes reduced the risk of IS. In addition, several SNPs interacted with alcohol consumption, body mass index ≥ 24 kg/m2 and cigarette smoking to affect serum lipid parameters such as triglyceride, high-density lipoprotein cholesterol, TC, and apolipoprotein A1 levels.Conclusions: Several SYTL3-SLC22A3 variants, especially the rs539298 SNP, several haplotypes, and G × E interactions, were related to blood lipid parameters and the risk of CAD and IS in the Southern Chinese Han population.

scholarly journals A genetic variant in the promoter of lncRNA MALAT1 is related to susceptibility of ischemic stroke

2019 ◽  
Author(s):  
yan wang ◽  
Xi-Xi Gu ◽  
Hua-Tuo Huang ◽  
Chun-Hong Liu ◽  
Gui-Jiang Wei ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Lung Adenocarcinoma ◽  
Protective Factor ◽  
Genetic Variant ◽  
Blood Lipid ◽  
Control Group ◽  
Lipid Levels ◽  
Lncrna Malat1 ◽  
Significant Difference ◽  
Blood Lipid Levels

Abstract Metastasis-associated lung adenocarcinoma transcript-1 (MALAT1) was aberrantly expressed in diverse diseases including ischemic stroke (IS). This study aimed to investigate the association between MALAT1 polymorphism and IS risk. We performed the genotyping of rs600231, rs1194338, rs4102217 and rs591291 in the promoter of MALAT1 by SNPscan method. Quantitative PCR was used to determine the levels of MALAT1 relative expression. We found the rs1194338 C>A variant in MALAT1 promoter was associated with IS risk (AC vs. CC: adjusted OR = 0.623, 95% CI, 0.417-0.932, P = 0.021; AA vs. CC: adjusted OR = 0.474, 95% CI, 0.226-0.991, P = 0.047; AC/AA vs. CC: adjusted OR = 0.596, 95% CI, 0.406-0.874, P = 0.008; A vs. C adjusted OR = 0.658, 95% CI, 0.487-0.890, P = 0.007). The IS patients showed higher expression levels of MALAT1 compared with the control group ( P < 0.05), but patients with AC/AA genotypes of rs1194338 have no significant difference compared to CC genotype ( P > 0.05). In addition, no significant differences were observed in blood lipid levels among SNPs of MALAT1 ( P > 0.05). These results suggest that the rs1194338 AC/AA genotypes may be a protective factor for IS, which mechanism needs to be further explored.

scholarly journals Effect of yoga therapy on cardiovascular parameters in patients with psoriasis: A randomized control trial — pilot study

2021 ◽  
Vol 4 (2) ◽  
pp. 61-63
Author(s):  
Ganesan Dayanidy ◽  
Ananda Balayogi Bhavanani ◽  
Meena Ramanathan ◽  
S Srikanth
Keyword(s):  
Diastolic Pressure ◽  
Medical Condition ◽  
Rate Pressure Product ◽  
Control Group ◽  
Double Product ◽  
Yoga Therapy ◽  
Yoga Group ◽  
Before And After ◽  
Mean Pressure ◽  
Therapy Education

This study was done at the Centre for Yoga Therapy, Education and Research (CYTER) of Sri Balaji Vidyapeeth (SBV) to determine cardiovascular (CV) parameters in patients with psoriasis.Data of 20 patients (12 female, 8 male) with a mean age of 44.40 ± 15.2ywho were referred by Dept. of Dermatology and attended yoga therapy sessions at CYTER was used for analysis. Supervised yoga training was given to the participants who were randomized into the yoga group. Heart rate (HR), systolic and diastolic pressure (SP and DP) was recorded using non-invasive blood pressure (NIBP) apparatus before and after the study period of 12 weeks. CV indices such as Pulse pressure (PP), mean pressure (MP), rate-pressure product (RPP), and double product (DoP) were derived using appropriate formulae.The inter-group comparison showed significant change (p&#60;0.05) in SP. The derived CV indices such as PP, RPP & DoP also showed significant changes. (p&#60;0.05) after 12 weeks of Yoga training. The intragroup comparison in the control group showed a significant increase in SP and DP (p&#60;0.05). There is a healthy reduction in SP and derived CV indices following 12 weeks of yoga training. The magnitude of this reduction depends on the pre-existing medical condition and intensity of the disease in each individual. These changes may be attributed to enhanced harmony of cardiac autonomic function as a result of coordinated breath-body work and mind-body relaxation due to yoga resulting in a significant reduction in the perceived stress.

scholarly journals Role of regular yoga practice in improvement of various pulmonary parameters in first year medical students

2018 ◽  
Vol 6 (7) ◽  
pp. 2523
Author(s):  
Kislay Kumar ◽  
Devesh Kumar ◽  
Pooja T. Pandey ◽  
Divya .
Keyword(s):  
Medical Students ◽  
Control Group ◽  
P Value ◽  
First Year ◽  
Pulmonary Functions ◽  
Yoga Group ◽  
The Subject ◽  
First Year Medical Students ◽  
And Control

Background: tress at any stage of life virtually produces several respiratory limitations and reduces tolerance to physical efforts, sometimes leading to pulmonary diseases in individuals. Various yoga and Pranayama like Kapalbhati and Nadi-sodhan involves powerful strokes of exhalation, which trains the subject to make full use of diaphragm and abdominal muscles.Methods: This study is performed on 1st yr. medical students whose stress level is in higher side due to academic burden. 55 medical students were selected as participants through counseling and were divided into Yoga group (n= 27) and control group (n=28). Pulmonary functions of subjects were tested using Pony FX advanced desktop spirometer manufactured by Cosmed. Yoga is performed 1 hr/day for 6 days /week for 12 weeks by yoga group.Results: Pulmonary functions tested in Yoga and control group were FVC, FEV1, PEF and FVC/FEV1. There were significant improvements in pulmonary functions in yoga group. In Yoga group (FVC- 5.8% increases, FEV1- 5.2% increase, PEF- 34% increase and FVC/FEV1- 3.15% increase). In control group also, all parameters increased but P value was not significant.Conclusions: This study concludes that practicing Yoga has shown a significant improvement on pulmonary functions in 1st year medical students.

scholarly journals Genetic Variants of CD40 Gene Are Associated with Coronary Artery Disease and Blood Lipid Levels

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Liting Zhou ◽  
Lin Xie ◽  
Dongchun Zheng ◽  
Na Li ◽  
Jian Zhu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Lipid ◽  
Control Group ◽  
Case Group ◽  
Lipid Levels ◽  
Chinese Han ◽  
Han Population ◽  
History Of ◽  
Blood Lipid Levels ◽  
T Haplotype

Objectives. The present study aimed to evaluate the effect ofCD40andCXCR4genes polymorphisms on CAD susceptibility and the blood lipid levels and history of cardiovascular risk factors in a Chinese Han population.Materials and Methods. A total of 583 unrelated patients with CAD and 540 controls were recruited. Two tag SNPs (rs4239702 and rs1535045) at theCD40locus and one tag SNP (rs2228014) at theCXCR4locus were genotyped using the SEQUENOM Mass-ARRAY system.Results. After adjusting the risk factors, the frequency of rs1535045-T allele was also higher in patients than controls. Haplotype analysis showed that the rs4239702(C)-rs1535045(T) haplotype was associated with CAD. People with rs4239702-TT genotype had higher blood lipid levels in case group while it was not in the control group. History of cardiovascular risk factors showed no association for the three SNPs in case group and control group.Conclusions. rs1535045 inCD40gene is likely to be associated with CAD in the Chinese Han population. rs4239702(C)-rs1535045(T) haplotype was associated with CAD. Only in CAD patients, the blood lipid level of patients with rs4239702-TT genotype was higher than other patients.CXCR4gene may not relate to CAD.

scholarly journals Lack of effect on blood lipid and calcium concentrations of young men on changing from white to wholemeal bread

1976 ◽  
Vol 35 (1) ◽  
pp. 55-60 ◽  
Author(s):  
K. W. Heaton ◽  
A. P. Manning ◽  
M. Hartog
Keyword(s):  
Plasma Cholesterol ◽  
Plasma Concentrations ◽  
Young Men ◽  
Blood Lipid ◽  
Male Students ◽  
Control Group ◽  
Lipid Levels ◽  
Free Living ◽  
Wholemeal Bread ◽  
Blood Lipid Levels

1. When nineteen ‘free-living’ male students, who normally ate 231 (SEM 14) g white bread/d changed to wholemeal bread for a 19-week period, there was no significant change in body-weight, plasma cholesterol or plasma triglyceride levels. These values, as well as plasma concentrations of calcium, phosphate, urate and haemoglobin, remained essentially the same as those for a control group.2. Increasing the wheat-fibre intake by eating wholemeal bread is not an effective method for reducing blood lipid levels, at least in healthy young men with a moderate bread intake.

scholarly journals Effects of Periodontal Disease and Periodontal Treatment on the Lipid Profile: A Sri Lankan Study

2016 ◽  
Vol 5 (2) ◽  
pp. 127-132
Author(s):  
WKL Perera ◽  
EAAP Amaratunga ◽  
R Sivakanesan
Keyword(s):  
Periodontal Disease ◽  
Lipid Profile ◽  
Test Group ◽  
Blood Lipid ◽  
Periodontal Treatment ◽  
Control Group ◽  
Sri Lankan ◽  
Lipid Levels ◽  
Periodontal Inflammation ◽  
Blood Lipid Levels

ABSTRACT Aims To compare the blood lipid levels of periodontitis group (of different severities) with a nonperiodontitis group and to evaluate any influence of periodontal treatment in altering blood lipid levels. Materials and methods The study sample consisted of 83 patients with periodontitis in the “test” group and a matched “control” group of 40, free of periodontitis according to predetermined selection criteria. All subjects underwent periodontal assessments and blood lipid estimation prior to treatment planning, following which they received active periodontal treatment/oral prophylaxis. Twelve weeks after treatment, periodontal reevaluations were carried out and blood lipids were reassessed for preand posttreatment comparisons. Results Increases in lipid levels were observed in the periodontitis group compared to the nonperiodontitis group at baseline. The test group had 5% higher mean total cholesterol than the control group at pretreatment/preintervention (albeit not significant: Student's t), while low-density lipoprotein cholesterol (LDL-Ch) was 6.6% higher in the test group than the control group (95% confidence interval). Mean triglycerides (Tri-G) were 5.7% higher in the control group than the test group, yet without statistical significance. All types of lipids in both the groups had decreased following periodontal therapy, while Tri-G levels demonstrated an opposite effect. Conclusion Patients with generalized severe periodontitis had higher LDL-Ch values than those with generalized mildmoderate periodontitis. Periodontal care was effective in lowering unfavorable serum lipids. Prompt control of periodontal inflammation would minimize development of deep periodontal infection and cardiovascular risk. How to cite this article Tilakaratne A, Perera WKL, Amaratunga EAAP, Sivakanesan R. Effects of Periodontal Disease and Periodontal Treatment on the Lipid Profile: A Sri Lankan Study. Int J Experiment Dent Sci 2016;5(2):127-132. Source of support University of Peradeniya Sri Lanka (Research Grant Number RG/2009/40/D).

scholarly journals Nephroprotective Impact of Adjuvant Yoga Therapy on Diabetes- A Randomised Controlled Trial

2020 ◽  
Author(s):  
Rajasekar Balaji ◽  
Meena Ramanathan ◽  
Ananda Balayogi Bhavanani
Keyword(s):  
Randomised Controlled Trial ◽  
Blood Sugar ◽  
Medical Management ◽  
Metabolic Diseases ◽  
Controlled Trial ◽  
Control Group ◽  
Diabetic Patients ◽  
Yoga Therapy ◽  
Yoga Group ◽  
Randomised Controlled

Introduction: Recent studies have provided abundant evidence about benefits of yoga in various chronic disorders. Diabetes Mellitus (DM) is a group of metabolic diseases characterised by chronic hyperglycaemia and renal complications of the disease are especially notable. It is estimated that 10% to 40% cases of Type 2 DM (T2DM) eventually end up having kidney failure. Yoga therapy may help to prevent progression of kidney damage in diabetic patients. Aim: To evaluate the effect of adjuvant yoga therapy on renal profile in diabetic patients. Materials and Methods: This single blind Randomised Controlled Trial (RCT) was designed as an interdisciplinary collaborative work between Centre for Yoga Therapy, Education and Research (CYTER) and Department of Endocrinology of Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth, Puducherry, India. A total of 72 diabetic patients with HbA1c, more than 7% were recruited and pre study evaluation of Fasting Blood Sugar (FBS), Postprandial Blood Sugar (PPBS), HbA1c, blood urea and serum creatinine were done. They were then randomised into control group (n=36) who received only standard medical management and yoga group (n=36) who received yoga therapy thrice weekly for 4 months along with standard medical management. Poststudy evaluation of all parameters was done at end of study period and data were analysed by Student’s paired and unpaired t-test for intra and intergroup comparisons. Results: Postinterventional comparisons revealed statistically significant reductions (p<0.001) in all glycaemic and renal parameters in the group receiving yoga therapy when compared with control group who didn’t receive the yoga intervention. Intragroup comparisons revealed significant reduction of all parameters in yoga group. Conclusion: It is concluded from the present RCT that yoga has a definite role as an adjuvant therapy as it enhances standard medical care and hence, can be recommended in routine clinical management of diabetes to prevent progression into complications that are part of the natural history of the disease.

Sign in / Sign up

Export Citation Format

Share Document