scholarly journals Clinical profile and outcomes of patients with acute pancreatitis and correlation with severity index from a tertiary care centre in South India-retrospective analysis

2021 ◽  
Vol 8 (6) ◽  
pp. 814
Author(s):  
Sultan Nawahir ◽  
Babu Kumar S. ◽  
Bala Kasi Naik ◽  
Ealai Athmarao Parthasarathy

Background: Acute pancreatitis is an inflammatory condition of the pancreas having a varied clinical presentation. It is one of the commonest causes of abdominal pain requiring hospital admission. This retrospective study aims to describe the clinical profile and outcomes of patients with acute pancreatitis and its correlation with severity index.Methods: All patients admitted with a diagnosis of acute pancreatitis to medical gastroenterology department between January 2018 to December 2020 were included in this retrospective study.Results: A total of 61 subjects were included in the final analysis. The mean age was 41.64, the ranged between 19 to 88 years. Among the study population, 53 (86.89%) were male and 8 (13.11%) were female. Among the people 43 (70.49%) were alcoholics, 22 (36.07%) were smokers, 11(18.03%) had systemic hypertension and 5 (8.20%) participants had type 2 diabetic mellitus. The mean CTSI was 2.15±2.82, the mean Balthazar was 3.43±2.4 and the mean procalcitonin was 2.52±9.28. The mean Lipase was 7822. There was a weak positive correlation between CTSI and CRP (rs value: 0.147, p=0.260). There was a weak negative correlation between Balthazar and CRP (rs value:-0.067, p=0.606).Conclusions: Among the study population, 87% of the patients were males. 70% of the population were alcoholics. Mean serum lipase was 7822. There was a weak positive correlation between CTSI and CRP (rs value: 0.147, p=0.260). There was a weak negative correlation between Balthazar and CRP (rs value:-0.067, p=0.606).

Author(s):  
Ashwini Akash Gite ◽  
Neha Mukkamala ◽  
Lata Parmar

BACKGROUND: Flexibility is important for general health and fitness, athletic performance, injury prevention and rehabilitation. Sedentary behavior of students leads to decreased physical fitness levels which affects flexibility. There is little evidence regarding relationship between BMI and flexibility. Aim: To study the relationship between BMI and flexibility and BMI and physical activity in young adults. Study Design: Observational study Place and Duration Of Study: The study was carried out at College of Physiotherapy, Sumandeep Vidyapeeth, Vadodara from September 2019 to March 2020. Methods: Males and females between 18 to 30 years were included in the study. BMI, Sit and Reach Test for low back and hamstring flexibility, Active Knee Extension Test (AKET) for hamstrings and Global Physical Activity Questionnaire (GPAQ) for physical activity levels were assessed. Results: 570 participants with mean age of 20.23±2.07 years were included. Mean BMI was 21.83±4.81 kg/m2. Number of females were 462 and males were 108. There was no significant correlation between BMI and flexibility of low back (P=.247) and hamstring (Rt) (P=.668) (Lt) (P=.354). BMI and GPAQ showed a statistically significant association (P=0.02). There was a weak positive correlation which was statistically significant between GPAQ and SART (P =0.000) and a weak negative correlation which was statistically significant between GPAQ and Rt AKET (P=0.004). Conclusion:  There was no significant correlation found between BMI and flexibility. There was a statistically significant association between BMI and physical activity, a weak negative correlation between GPAQ and hamstring flexibility and weak positive correlation between GPAQ and SART.


2021 ◽  
Vol 12 (3) ◽  
pp. 2280-2285
Author(s):  
Akash S Wallepure ◽  
Salin Sebastian ◽  
Sradha S Thomas ◽  
Nishant Khatiwada ◽  
Divya Mol E C ◽  
...  

Tuberculosis (TB) is a highly contagious airborne disease caused by Mycobacterium tuberculosis that primarily affects the lungs. TB is a significant and major public health emergency globally. According to the WHO Global Tuberculosis Report 2020, 10 million people developed TB disease in the year 2019. The main objective of the study was to assess the level of knowledge, attitude and practice in TB patients. The study also reveals the association between KAP and the demographics of the subjects. An observational study was employed to collect data from a total of 71 subjects. Both quantitative and qualitative statistical analysis were adopted. From the findings, the mean age of the study population was 45.5 ± 13.96 years. Over 15.50% of subjects appeared to have adequate knowledge, 87.33% of subjects had a fair attitude, and around 58% of subjects were reported to have good practices towards TB. A weak positive correlation between knowledge and attitude (p = 0.051), weak positive correlation between knowledge and practice (p = 0.138) whereas, a significant and moderately positive correlation between attitude and practice (p = 0.002) was observed. The mean knowledge scores of graduates and post-graduates were higher in comparison with other study subjects. The study findings showed that the majority of subjects had several misconceptions about TB and hence prioritized interventions and more awareness programs at the root levels are needed to aid TB control and eradication.


2020 ◽  
Vol 30 (4) ◽  
Author(s):  
Srilaning Driyah ◽  
Julianty Pradono

Diabetes mellitus type 2 (T2DM) is a chronic disease and can cause complications, one of which is decreased kidney function. Anemia is a complication of T2DM, especially if it is accompanied by renal disorders. The aim of this study was to show the relationship between HbA1c and hemoglobin (Hb), hematocrit (HCT), creatinine, and glomerular filtration rate (GFR) in T2DM respondents with and without complications of chronic renal failure (CRF). This study used a subset of the Non-Communicable Diseases cohort data set by the Center for Public Health Efforts in Central Bogor sub-district, Bogor City. The research design was an analytic observational study. Respondents were all T2DM with complete data as much as 303 people. The respondents diagnosed based on the results of previous blood sugar tests. The inclusion criteria were people with T2DM who had complete data (HBA1c, Hb, HCT, and creatinine). Bivariate analysis between the dependent variable (T2DM with or without CRF) and the independent variable (HbA1c, Hb, HCT, creatinine, and LFG) used the Spearman correlation. The results showed a strong positive correlation between HbA1c and Hb (r = 0,66, p<0,05) and HCT (r = 0,67, p<0,05)in T2DM respondents with CRF, but there is no correlation between HbA1c and creatinine and LFG. In T2DM without CRF there is a weak positive correlation between HbA1c and Hb (r = 0,26, p<0,05) and HCT (r = 0,21, p<0,05), a negative correlation between HbA1c and creatinine (r = -0,29, p<0,05), and there is a weak positive correlation between HbA1c and LFG (r = 0,24, p<0,05 ). The conclusion is that controlling blood sugar by examining HbA1c levels shows a strong positive correlation with Hb levels and HCT in T2DM with CRF and a weak negative correlation with LFG in T2DM without CRF. This difference is not in accordance with the existing theory Abstrak  Diabetes melitus tipe 2 (DMT2) merupakan penyakit kronik dan dapat menimbulkan komplikasi, salah satunya adalah penurunan fungsi ginjal. Anemia merupakan komplikasi DMT2 khususnya jika disertai gangguan renal. Tujuan penelitian ini menunjukkan hubungan hemoglobin A1c (HbA1c) dengan hemoglobin (Hb), hematokrit (HCT), kreatinin, dan laju filtrasi glomerulus (LFG) pada responden DMT2 dengan dan tanpa komplikasi gagal ginjal kronik (GGK). Penelitian ini menggunakan subset data kohor penyakit tidak menular (PTM) yang dilakukan oleh Puslitbang Upaya Kesehatan Masyarakat di Kecamatan Bogor Tengah, Kota Bogor. Desain penelitian adalah studi observasional analitik. Responden adalah semua penderita DMT2 dengan data lengkap sebanyak 303 orang yang didiagnosis berdasarkan hasil pemeriksaan gula darah sebelumnya. Kriteria inklusi adalah penderita DMT2 yang memiliki data lengkap (HbA1c, Hb, HCT, dan kreatinin). Analisis bivariat antara variabel dependen (DMT2 dengan atau tanpa GGK) dengan variabel independen (HbA1c, Hb, HCT, kreatinin dan LFG) mengunakan korelasi Spearman. Hasil penelitian menunjukkan pada responden DMT2 dengan GGK terdapat korelasi positif yang kuat antara HbA1c dengan Hb (r = 0,66, p<0,05) dan HCT (r = 0,67, p<.0,05). Sedangkan HbA1c dengan kreatin dan LFG tidak terdapat korelasi. Pada DMT2 tanpa GGK terdapat korelasi positif lemah antara HbA1c dengan Hb (r = 0,26, p<0,05 ) dan HCT (r = 0,21, p<0,05), terjadi korelasi negatif antara HbA1c dengan kreatinin sebesar (r = -0,29, p<0,05), dan terdapat korelasi positif lemah antara HbA1c dengan LFG ( r = 0,24, p<0,05 ). Simpulan yang dapat diambil adalah pengontrolan gula darah dengan pemeriksaan kadar HbA1c menunjukkan korelasi positif yang kuat dengan kadar Hb dan HCT pada DMT2 dengan GGK dan korelasi negatif lemah dengan LFG pada DMT2 tanpa GGK. Perbedaan tersebut belum sesuai teori yang ada.


2018 ◽  
pp. 1064-1073 ◽  
Author(s):  
Essam S. Soliman ◽  
Nahla H. Sallam ◽  
Eman M. Abouelhassan

Aim: Broilers' optimum performance in response to their genetic potential depends on litter environment which is ideal for bacterial survival and coccidian oocyst sporulation. An in vitro evaluation was conducted for the effectiveness of superphosphate, meta-bisulfide, and charcoal litter amendments in minimizing Escherichia coli O157:H7 and Salmonella Typhimurium survival, Eimeria oocyst count, and sporulation. Materials and Methods: Three groups of 16 litter trays were prepared and inoculated with E. coli O157:H7, S. Typhimurium, and Eimeria non-sporulated oocyst. A set of four trays in each group was designed for each one of the chemical amendments. A total of 720 litter samples were collected and examined for bacterial counts, Eimeria oocyst count, and sporulation during the experimental period (35 days). Results: Litter moisture and pH revealed a highly significant (p<0.001) reduction in all treated litter trays compared to control. Total bacterial count (TBC), total Enterobacteriaceae count, and S. Typhimurium count showed a highly significant (p<0.001) reduction in meta-bisulfide-treated trays compared to other amendments and positive control. Meanwhile, Eimeria oocyst count and sporulation revealed a highly significant (p<0.001) reduction in superphosphate, meta-bisulfide, and charcoal-treated trays, respectively. Temperature revealed a highly significant (p<0.001) weak positive correlation with pH of all inoculated trays, a highly significant (p<0.001) weak negative correlation with moisture percentage of E. coli O157:H7 and S. Typhimurium inoculated trays, and a highly significant (p<0.001) weak negative correlation with TBC. Meanwhile, relative humidity revealed significant (p≤0.005) weak positive correlation with moisture percentage of E. coli O157:H7 inoculated trays. Conclusion: The study concluded that regular usage with periodical reapplication of litter amendments as meta-bisulfide or superphosphate in poultry farms is one of the indispensable managemental and preventive measures for minimizing bacterial survival and inhibiting Eimeria oocyst maturation and sporulation. Keywords: charcoal, Eimeria, Escherichia coli, litter, meta-bisulfide, Salmonella, superphosphate.


1985 ◽  
Vol 108 (2) ◽  
pp. 277-283 ◽  
Author(s):  
S. Andò ◽  
C. Giacchetto ◽  
G. M. Colpi ◽  
E. Beraldi ◽  
M. L. Panno ◽  
...  

Abstract. In the present study we determined progesterone (p), 17-OH-progesterone (17-OH-P), androstenedione (Δ4), dehydroepiandrosterone (DHEA) and testosterone (T) in spermatic venous blood of 34 varicocele patients and of 13 normal subjects. We also used the DHEA/Δ4 ratio as an index of the Δ5/Δ4 pathway ratio in testosterone biosynthesis. The mean of T and Δ4 in the spermatic blood of varicocele (V) patients appeared to be significantly lower with respect to that of normal (N) subjects (T:N = 1718.2 ± 202.4 (sem) nmol/l, No. 11; V = 1243.7 ± 97 (sem) nmol/l, No. 34; P < 0.03. Δ4: N = 56.4 ± 5.6 (sem) nmol/l, No. 12; V = 38.1 ± 4 (sem) nmol/l, No. 27, 0.02> P>0.01). A negative correlation was observed between the individual age of varicocele patients and 17-OH-P (No. 34, y = −30.66x + 1300, r = −0.57, P < 0.01) Δ4 values (No. 27, y = −1.981x + 96.52, r = −0.67, P< 0.01). When the ratio of T precursors was evaluated, we observed a positive correlation between the P/17-OH-P ratio and age of varicocele (No. 33, y = 0.0065x–0.092, r = 0.45, P < 0.03). The 17-OH-P/Δ4 ratio was greatly increased with respect to that of normal subjects (N = 5.12 ± (sem), No. 12; V= 10.77 ± 1.31 (sem), No. 27; P<0.01). These data suggest that the reduced T levels in spermatic venous blood of varicocele patients were due firstly to the enzymatic deficiency of 17-20-lyase and secondly to that of 17α-hydroxylase activity as the patients grow relatively older. The negative correlation between the DHEA/Δ4 ratio and Δ4/T ratio was observed in normal subjects (No. 10, y = −0.00432x + 0.0542, r = −0.67, P < 0.03) as well as in varicocele patients (No. 27, y = −0.00399x + 0.0587, r = −0.48, 0.02 > P > 0.01). This indicates that in the testis of varicocele patients the testosterone remains prevalently supplied by the Δ5 pathway of biosynthesis.


1946 ◽  
Vol 36 (4) ◽  
pp. 260-262 ◽  
Author(s):  
James Anderson

The mean sugar content of bull semen was 470±11·7 mg. %. There was no relationship between the sugar content and the volume of the ejaculate, the number of sperm per c.mm., the initial motility and the maintenance of high motility during storage.The mean percentage reduction in sugar after 24 hr. for undiluted semen stored at 10° C. was 23·85 ·1±76%. There was a significant positive correlation between the sugar reduction and initial motility, and a highly significant positive correlation between sugar reduction and the concentration of sperm. The negative correlation between reduction in sugar and the period for which good motility was retained on storage was not significant.


2021 ◽  
Vol 4 (2) ◽  
pp. 171
Author(s):  
Tatak Setiadi

Millennials' networks within the triple helix of University-Industry-Government show unusual communication structures and are challenging to be revealed. Using the direct and online written interview with the millennials found about 817 relations (edges) to 347 actors (nodes) in total. Analysis by Social Network Analysis (SNA) found: (1) the dominant issues of the maritime human resources are about future work prospects and specialties field, imbalance of supply and demand of maritime human resources, and improvement needed of industry's human resources (2) the dominant skill issue is capacity building and continuous learning, (3) the highest degree of centrality and closeness centrality has resulted from Industry, (4) the highest betweenness centrality and eigenvector centrality has resulted from University, (5) there is moderate positive correlation of ages to closeness centrality and weak negative correlation to eigenvector centrality, (6) there is a moderate positive correlation of education levels to closeness centrality, (7) there is a weak negative correlation of gender to eigenvector centrality, and (8) there is a statist relation of the triple helix in discussing maritime issues.


2019 ◽  
Vol 34 (2) ◽  
pp. 11-15
Author(s):  
Miguel Crisostomo ◽  
Celso Ureta

Objective: To evaluate the association of salivary pH and taste sensitivity among geriatric and non-geriatric patients in an otorhinolaryngology - head and neck surgery out-patient clinic. Methods: Design:           Cross-Sectional Study Setting:           Tertiary Government Training Hospital Participants: 40 otorhinolaryngology out-patients   Results: Of the 40 patients aged 24 to 92-years-old (mean age 59.8 years), 21 were geriatric and 19 were non-geriatric. The mean salivary pH was 6.66 (range 5 to 8) and 6.63 (range 5 to 7) for geriatric and non-geriatric groups; the difference in mean salivary pH was not statistically significant (p = .87). The salivary pH in the geriatric group showed a negative correlation with age (r=0.06), while the salivary pH in the non-geriatric group had a positive correlation with age (r=0.14). Overall, increases in age among the non-geriatric group were correlated with increase in salivary pH which were not observed in the geriatric patients. In the geriatric group, among the 4 tastants, the strongest correlation between taste sensitivity and salivary pH was observed for quinine followed by sucrose and NaCl, but no correlation for citric acid. In the non-geriatric group, the strongest correlation between taste sensitivity and salivary pH was observed for NaCl, followed by quinine, citric acid and sucrose. Conclusion: There was no significant difference between the mean salivary pH of geriatric and non-geriatric patients, and both means were within normal. There was a negative correlation between age and salivary pH in the geriatric group, and a positive correlation in the non-geriatric group.  Salivary pH had the strongest correlation with taste sensitivity for quinine and NaCl among geriatric and non-geriatric participants, respectively, but the reasons for, and significance of this cannot be inferred from the present study. Keywords: salivary pH; taste sensitivity; gustatory function; geriatric 


2014 ◽  
Vol 5 (4) ◽  
pp. 21-24
Author(s):  
Mosin Mushtaq ◽  
Abid H Wani ◽  
Faud Sadiq ◽  
Mudasir Mushtaq ◽  
Sameena Tabassum ◽  
...  

Background and study aims: Hypertriglyceridemia can be a primary cause for acute pancreatitis or secondary to other factors prior to the increase of lipid levels, or both. The aim of our study was to assess the severity of acute pancreatitis with elevation in serum triglyceride levels and report the outcomes of our series. Patients and methods: One hundred twenty?six patients of acute pancreatitis were admitted within 72 hours of onset of symptoms, out of whom 26 patients were excluded during the course of study due to preexisting comorbidities. 100 patients in the study population were divided into group A having serum triglyceride levels ≥500 mg/dl (n = 30) and group B having <500 mg/dl (n = 70) at the time of admission. Results: The mean age of group A was similar to group B (50.2 ± 17.1 vs 49.26 ± 17.2 years; p = 0.860). Most common etiological factor of acute pancreatitis was found to be gall stones (56%) in both groups. Ranson's score at admission in group A was 2.93 ± 0.22 and in group B it was 1.34 ± 0.99. Mortality below two weeks was noted in (12/30, 40%) of group A and (6/70, 8%) of group B patients, which was statistically significant, (p = 0.015). Conclusions: The final conclusion of this study was that patients of acute pancreatitis with elevated triglyceride levels form a morbid group and these should be monitored aggressively for the development of any complications. DOI: http://dx.doi.org/10.3126/ajms.v5i4.9971 Asian Journal of Medical Sciences 2014 Vol.5(4); 21-24


Author(s):  
M. Koteshwar Rao ◽  
P. Lakshmi Narayana Reddy

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">Frontal plane knee malalignment may increase the progression of knee osteoarthritis (OA) and worsen functional capacity</span><span lang="EN-IN">.</span></p><p class="abstract"><strong>Methods:</strong> <span lang="EN-IN">In our study, the aim was to find the correlation of frontal plane tibiofemoral alignment with knee pain in early OA knee patients. After meeting the inclusion and exclusion criteria, 195 patients with 314 knees (104 females, 91 males) were studied. Clinical and radiological measurements of frontal plane tibiofemoral alignment, using landmark of hip, knee, and ankle, compared with knee pain</span>.<strong></strong></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">The accepted Statistical significance was p&lt;0.05. Patients with 130 knees (41%) were normal alignment, and 184 knees (59%) were abnormal alignment. The mean±SD age in our study was 54.6±8.9 years. The mean±SD BMI in our study to be 25.86±1.96. Mean±SD Q-angle in patients with normal and abnormal alignment was 14.76±1.54 and 14.63±1.9 respectively. There is statistically no significant correlation between BMI and VAS score (r=0.054, p=0.344). Means±SD of mLDFA, mMPTA, mTFA, aTFA, and JOA were 88.86±2.73, 84.96±3.00, 5.96±4.01, 4.55±3.67, and 2.37±1.88 respectively. JOA and mTFA had statistically significant weak positive correlation with VAS (knee pain) score, (r=0.281) (p=0.000) and (r=0.236) (p=0.000) respectively. The rest of the angles were not had statistically significant correlation with VAS score. The mTFA had statistically significant weak positive correlation with all the angles. We found that Frontal plane tibiofemoral alignment correlates with knee pain in patients with early OA</span><span lang="EN-IN">. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">The mTFA may be considered one important criterion in designing treatment and planning surgery for patients with primary osteoarthritis. The Q angle acts as a good alternative clinical tool in assessing frontal plane alignment. BMI was not correlating with knee pain (VAS score)</span><span lang="EN-IN">.</span></p>


Sign in / Sign up

Export Citation Format

Share Document