scholarly journals Korelasi Hemoglobin A1c dengan Hemoglobin dan Laju Filtrasi Glomerulus Penderita Diabetes dengan dan tanpa Komplikasi Gagal Ginjal Kronik di Bogor

2020 ◽  
Vol 30 (4) ◽  
Author(s):  
Srilaning Driyah ◽  
Julianty Pradono

Diabetes mellitus type 2 (T2DM) is a chronic disease and can cause complications, one of which is decreased kidney function. Anemia is a complication of T2DM, especially if it is accompanied by renal disorders. The aim of this study was to show the relationship between HbA1c and hemoglobin (Hb), hematocrit (HCT), creatinine, and glomerular filtration rate (GFR) in T2DM respondents with and without complications of chronic renal failure (CRF). This study used a subset of the Non-Communicable Diseases cohort data set by the Center for Public Health Efforts in Central Bogor sub-district, Bogor City. The research design was an analytic observational study. Respondents were all T2DM with complete data as much as 303 people. The respondents diagnosed based on the results of previous blood sugar tests. The inclusion criteria were people with T2DM who had complete data (HBA1c, Hb, HCT, and creatinine). Bivariate analysis between the dependent variable (T2DM with or without CRF) and the independent variable (HbA1c, Hb, HCT, creatinine, and LFG) used the Spearman correlation. The results showed a strong positive correlation between HbA1c and Hb (r = 0,66, p<0,05) and HCT (r = 0,67, p<0,05)in T2DM respondents with CRF, but there is no correlation between HbA1c and creatinine and LFG. In T2DM without CRF there is a weak positive correlation between HbA1c and Hb (r = 0,26, p<0,05) and HCT (r = 0,21, p<0,05), a negative correlation between HbA1c and creatinine (r = -0,29, p<0,05), and there is a weak positive correlation between HbA1c and LFG (r = 0,24, p<0,05 ). The conclusion is that controlling blood sugar by examining HbA1c levels shows a strong positive correlation with Hb levels and HCT in T2DM with CRF and a weak negative correlation with LFG in T2DM without CRF. This difference is not in accordance with the existing theory Abstrak  Diabetes melitus tipe 2 (DMT2) merupakan penyakit kronik dan dapat menimbulkan komplikasi, salah satunya adalah penurunan fungsi ginjal. Anemia merupakan komplikasi DMT2 khususnya jika disertai gangguan renal. Tujuan penelitian ini menunjukkan hubungan hemoglobin A1c (HbA1c) dengan hemoglobin (Hb), hematokrit (HCT), kreatinin, dan laju filtrasi glomerulus (LFG) pada responden DMT2 dengan dan tanpa komplikasi gagal ginjal kronik (GGK). Penelitian ini menggunakan subset data kohor penyakit tidak menular (PTM) yang dilakukan oleh Puslitbang Upaya Kesehatan Masyarakat di Kecamatan Bogor Tengah, Kota Bogor. Desain penelitian adalah studi observasional analitik. Responden adalah semua penderita DMT2 dengan data lengkap sebanyak 303 orang yang didiagnosis berdasarkan hasil pemeriksaan gula darah sebelumnya. Kriteria inklusi adalah penderita DMT2 yang memiliki data lengkap (HbA1c, Hb, HCT, dan kreatinin). Analisis bivariat antara variabel dependen (DMT2 dengan atau tanpa GGK) dengan variabel independen (HbA1c, Hb, HCT, kreatinin dan LFG) mengunakan korelasi Spearman. Hasil penelitian menunjukkan pada responden DMT2 dengan GGK terdapat korelasi positif yang kuat antara HbA1c dengan Hb (r = 0,66, p<0,05) dan HCT (r = 0,67, p<.0,05). Sedangkan HbA1c dengan kreatin dan LFG tidak terdapat korelasi. Pada DMT2 tanpa GGK terdapat korelasi positif lemah antara HbA1c dengan Hb (r = 0,26, p<0,05 ) dan HCT (r = 0,21, p<0,05), terjadi korelasi negatif antara HbA1c dengan kreatinin sebesar (r = -0,29, p<0,05), dan terdapat korelasi positif lemah antara HbA1c dengan LFG ( r = 0,24, p<0,05 ). Simpulan yang dapat diambil adalah pengontrolan gula darah dengan pemeriksaan kadar HbA1c menunjukkan korelasi positif yang kuat dengan kadar Hb dan HCT pada DMT2 dengan GGK dan korelasi negatif lemah dengan LFG pada DMT2 tanpa GGK. Perbedaan tersebut belum sesuai teori yang ada.

Author(s):  
Ashwini Akash Gite ◽  
Neha Mukkamala ◽  
Lata Parmar

BACKGROUND: Flexibility is important for general health and fitness, athletic performance, injury prevention and rehabilitation. Sedentary behavior of students leads to decreased physical fitness levels which affects flexibility. There is little evidence regarding relationship between BMI and flexibility. Aim: To study the relationship between BMI and flexibility and BMI and physical activity in young adults. Study Design: Observational study Place and Duration Of Study: The study was carried out at College of Physiotherapy, Sumandeep Vidyapeeth, Vadodara from September 2019 to March 2020. Methods: Males and females between 18 to 30 years were included in the study. BMI, Sit and Reach Test for low back and hamstring flexibility, Active Knee Extension Test (AKET) for hamstrings and Global Physical Activity Questionnaire (GPAQ) for physical activity levels were assessed. Results: 570 participants with mean age of 20.23±2.07 years were included. Mean BMI was 21.83±4.81 kg/m2. Number of females were 462 and males were 108. There was no significant correlation between BMI and flexibility of low back (P=.247) and hamstring (Rt) (P=.668) (Lt) (P=.354). BMI and GPAQ showed a statistically significant association (P=0.02). There was a weak positive correlation which was statistically significant between GPAQ and SART (P =0.000) and a weak negative correlation which was statistically significant between GPAQ and Rt AKET (P=0.004). Conclusion:  There was no significant correlation found between BMI and flexibility. There was a statistically significant association between BMI and physical activity, a weak negative correlation between GPAQ and hamstring flexibility and weak positive correlation between GPAQ and SART.


2017 ◽  
Vol 5 (1) ◽  
pp. 33-39
Author(s):  
Mahani Yusoff ◽  
Muhammad Arieff Mat Shukri ◽  
Norrimi Rosaida Awang ◽  
Musfiroh Jani ◽  
Zairah Ab Kadir ◽  
...  

The present study was focusing to characterize the particulate matter (PM2.5 and PM10) at the roadside of First Penang Bridge and the associated meteorological parameters influence such as precipitation, temperature, and relative humidity. The study was conducted by focusing on the roadside area of First Penang Bridge (N05°21.375’; E100°23.584’). A total of 12 samples thrice per month for each particulate matter size were collected starting from June 2015 to September 2015. Meteorological data were obtained from the Meteorological Department of Penang on a daily basis and 24-hours averages. Descriptive statistical analysis was conducted in characterizing the relationship between particulate matter concentrations and the target meteorological parameters. Results showed that PM2.5 and PM10 concentrations ranged between 18.06 – 79.51 ?g/m3 and 22.38 – 130.90 ?g/m3 with the overall mean concentration of 39.35 ?g/m3 for PM2.5 and 45.24 ?g/m3 for PM10. For the PM2.5, weak negative correlation was obtained between PM and precipitation (r = -0.462), strong negative correlation with relative humidity (r = -0.799) and weak positive correlation between temperature (r = 0.456). PM10 showed weak negative correlation between PM with temperature (r = -0.061) and precipitation (r = -0.022), and strong positive correlation between PM and relative humidity (r = 0.130).


2021 ◽  
Vol 8 (6) ◽  
pp. 814
Author(s):  
Sultan Nawahir ◽  
Babu Kumar S. ◽  
Bala Kasi Naik ◽  
Ealai Athmarao Parthasarathy

Background: Acute pancreatitis is an inflammatory condition of the pancreas having a varied clinical presentation. It is one of the commonest causes of abdominal pain requiring hospital admission. This retrospective study aims to describe the clinical profile and outcomes of patients with acute pancreatitis and its correlation with severity index.Methods: All patients admitted with a diagnosis of acute pancreatitis to medical gastroenterology department between January 2018 to December 2020 were included in this retrospective study.Results: A total of 61 subjects were included in the final analysis. The mean age was 41.64, the ranged between 19 to 88 years. Among the study population, 53 (86.89%) were male and 8 (13.11%) were female. Among the people 43 (70.49%) were alcoholics, 22 (36.07%) were smokers, 11(18.03%) had systemic hypertension and 5 (8.20%) participants had type 2 diabetic mellitus. The mean CTSI was 2.15±2.82, the mean Balthazar was 3.43±2.4 and the mean procalcitonin was 2.52±9.28. The mean Lipase was 7822. There was a weak positive correlation between CTSI and CRP (rs value: 0.147, p=0.260). There was a weak negative correlation between Balthazar and CRP (rs value:-0.067, p=0.606).Conclusions: Among the study population, 87% of the patients were males. 70% of the population were alcoholics. Mean serum lipase was 7822. There was a weak positive correlation between CTSI and CRP (rs value: 0.147, p=0.260). There was a weak negative correlation between Balthazar and CRP (rs value:-0.067, p=0.606).


2018 ◽  
pp. 1064-1073 ◽  
Author(s):  
Essam S. Soliman ◽  
Nahla H. Sallam ◽  
Eman M. Abouelhassan

Aim: Broilers' optimum performance in response to their genetic potential depends on litter environment which is ideal for bacterial survival and coccidian oocyst sporulation. An in vitro evaluation was conducted for the effectiveness of superphosphate, meta-bisulfide, and charcoal litter amendments in minimizing Escherichia coli O157:H7 and Salmonella Typhimurium survival, Eimeria oocyst count, and sporulation. Materials and Methods: Three groups of 16 litter trays were prepared and inoculated with E. coli O157:H7, S. Typhimurium, and Eimeria non-sporulated oocyst. A set of four trays in each group was designed for each one of the chemical amendments. A total of 720 litter samples were collected and examined for bacterial counts, Eimeria oocyst count, and sporulation during the experimental period (35 days). Results: Litter moisture and pH revealed a highly significant (p<0.001) reduction in all treated litter trays compared to control. Total bacterial count (TBC), total Enterobacteriaceae count, and S. Typhimurium count showed a highly significant (p<0.001) reduction in meta-bisulfide-treated trays compared to other amendments and positive control. Meanwhile, Eimeria oocyst count and sporulation revealed a highly significant (p<0.001) reduction in superphosphate, meta-bisulfide, and charcoal-treated trays, respectively. Temperature revealed a highly significant (p<0.001) weak positive correlation with pH of all inoculated trays, a highly significant (p<0.001) weak negative correlation with moisture percentage of E. coli O157:H7 and S. Typhimurium inoculated trays, and a highly significant (p<0.001) weak negative correlation with TBC. Meanwhile, relative humidity revealed significant (p≤0.005) weak positive correlation with moisture percentage of E. coli O157:H7 inoculated trays. Conclusion: The study concluded that regular usage with periodical reapplication of litter amendments as meta-bisulfide or superphosphate in poultry farms is one of the indispensable managemental and preventive measures for minimizing bacterial survival and inhibiting Eimeria oocyst maturation and sporulation. Keywords: charcoal, Eimeria, Escherichia coli, litter, meta-bisulfide, Salmonella, superphosphate.


2015 ◽  
Vol 2015 ◽  
pp. 1-15 ◽  
Author(s):  
Gang Lin ◽  
Jingying Fu ◽  
Dong Jiang ◽  
Jianhua Wang ◽  
Qiao Wang ◽  
...  

Epidemiological studies around the world have reported that fine particulate matter (PM2.5) is closely associated with human health. The distribution of PM2.5concentrations is influenced by multiple geographic and socioeconomic factors. Using a remote-sensing-derived PM2.5dataset, this paper explores the relationship between PM2.5concentrations and meteorological parameters and their spatial variance in China for the period 2001–2010. The spatial variations of the relationships between the annual average PM2.5, the annual average precipitation (AAP), and the annual average temperature (AAT) were evaluated using the Geographically Weighted Regression (GWR) model. The results indicated that PM2.5had a strong and stable correlation with meteorological parameters. In particular, PM2.5had a negative correlation with precipitation and a positive correlation with temperature. In addition, the relationship between the variables changed over space, and the strong negative correlation between PM2.5and the AAP mainly appeared in the warm temperate semihumid region and northern subtropical humid region in 2001 and 2010, with some localized differences. The strong positive correlation between the PM2.5and the AAT mainly occurred in the mid-temperate semiarid region, the humid, semihumid, and semiarid warm temperate regions, and the northern subtropical humid region in 2001 and 2010.


2020 ◽  
pp. 126-126
Author(s):  
Milovan Stojanovic ◽  
Marina Deljanin-Ilic ◽  
Stevan Ilic ◽  
Dejan Petrovic ◽  
Bojan Ilic

Background / Aim. Well-organized cardiovascular rehabilitation (CVR) reduces cardiovascular burden by influencing cardiovascular risk factors, improving the quality of life and reducing mortality and hospital readmission. However, its effects on hemodynamic status are largely unknown. The aim of our study was to evaluate the influence of three-week CVR program on hemodynamic status and to investigate if there is a correlation between physical strain tolerance and hemodynamic parameters measured by impedance cardiography (ICG) before and after CVR program in patients with coronary artery disease. Methods. Fifty-two patients attended a three-week CVR program. At the beginning and at the end of rehabilitation program laboratory tests, exercise stress tests (EST) and ICG measurements were taken. Results. Patients showed better strain tolerance on the second exercise stress test (EST2) by achieving higher strain level (Z=2,315; p=0,021) and longer duration of test (Z=2,305; p=0,021). There was a strong positive correlation between the level of EST2 and cardiac output (CO) (r=0,538; p<0,001) and stroke volume (SV) (r=0,380; p=0,017) on the second ICG (ICG2). Also, there was a strong negative correlation between EST2 level and systemic vascular resistance (SVR) (r=-0,472; p=0,002) and SVR index (SSVRI) (r=-0,407; p=0,010) on ICG2. There was a strong positive correlation between EST2 duration and CO (r=0.517; p=0.001) as well as between EST2 duration and SV (r=0.340; p=0.034), and a strong negative correlation between EST2 duration and SVR (r=-0.504; p=0.001) as well as between EST2 duration and SVRI (r=-0.448; p=0.004), according to ICG2. Conclusion. Our study showed that a well-designed CVR program can lead to better physical strain tolerance. Furthermore, CVR led to a significant positive correlation between EST and cardiac output as well as between EST and stroke volume measured by ICG. On the other hand, there was a significant negative correlation between EST and vascular related parameters according to ICG at the end of the CVR program.


2008 ◽  
Vol 191 (1) ◽  
pp. 65-73 ◽  
Author(s):  
Pavel S. Novichkov ◽  
Yuri I. Wolf ◽  
Inna Dubchak ◽  
Eugene V. Koonin

ABSTRACT In order to explore microevolutionary trends in bacteria and archaea, we constructed a data set of 41 alignable tight genome clusters (ATGCs). We show that the ratio of the medians of nonsynonymous to synonymous substitution rates (dN/dS) that is used as a measure of the purifying selection pressure on protein sequences is a stable characteristic of the ATGCs. In agreement with previous findings, parasitic bacteria, notwithstanding the sometimes dramatic genome shrinkage caused by gene loss, are typically subjected to relatively weak purifying selection, presumably owing to relatively small effective population sizes and frequent bottlenecks. However, no evidence of genome streamlining caused by strong selective pressure was found in any of the ATGCs. On the contrary, a significant positive correlation between the genome size, as well as gene size, and selective pressure was observed, although a variety of free-living prokaryotes with very close selective pressures span nearly the entire range of genome sizes. In addition, we examined the connections between the sequence evolution rate and other genomic features. Although gene order changes much faster than protein sequences during the evolution of prokaryotes, a strong positive correlation was observed between the “rearrangement distance” and the amino acid distance, suggesting that at least some of the events leading to genome rearrangement are subjected to the same type of selective constraints as the evolution of amino acid sequences.


2021 ◽  
Vol 4 (2) ◽  
pp. 171
Author(s):  
Tatak Setiadi

Millennials' networks within the triple helix of University-Industry-Government show unusual communication structures and are challenging to be revealed. Using the direct and online written interview with the millennials found about 817 relations (edges) to 347 actors (nodes) in total. Analysis by Social Network Analysis (SNA) found: (1) the dominant issues of the maritime human resources are about future work prospects and specialties field, imbalance of supply and demand of maritime human resources, and improvement needed of industry's human resources (2) the dominant skill issue is capacity building and continuous learning, (3) the highest degree of centrality and closeness centrality has resulted from Industry, (4) the highest betweenness centrality and eigenvector centrality has resulted from University, (5) there is moderate positive correlation of ages to closeness centrality and weak negative correlation to eigenvector centrality, (6) there is a moderate positive correlation of education levels to closeness centrality, (7) there is a weak negative correlation of gender to eigenvector centrality, and (8) there is a statist relation of the triple helix in discussing maritime issues.


2020 ◽  
Vol 3 (3) ◽  
pp. 315-328
Author(s):  
Herbert Mapira Tendayi ◽  
Jerome Ndayisenga ◽  
Solange Nyiramahirwe ◽  
Jacqueline Mukanshuti ◽  
Valens Karenzi ◽  
...  

Background Infertility remains a highly prevalent global condition in the second decade of the new millennium. Reproductive hormones determine sperm quality as they initiate and maintain spermatogenesis. Hormonal imbalance can cause abnormal sperm quality that can be treated by hormonal replacement therapy. Objective To assess the relationship between sperm quality and male reproductive hormones among male partners with fertility complications attending CHUB. Methods The study was a descriptive cross-sectional, and a convenient sampling strategy was used to recruit subjects at CHUB. Sixty-two male subjects with fertility complications provided both semen and blood sample to analyze sperm quality and reproductive hormones. Descriptive statistics were used to analyze data. Results Both FSH and LH showed a strong negative correlation with sperm count which is more profound with FSH (r= -0.722) than LH (r= -0.545). Testosterone showed a strong positive correlation with sperm count (r= 0.712). FSH and LH showed a negative correlation with sperm motility which is more profound in FSH (r= -0.312) than LH (r= -0.302). Testosterone also showed a positive correlation with sperm motility (r= 0.360). Conclusion Our study found a correlation between sperm quality and male reproductive hormones. We further suggest other studies to investigate predictive power of male reproductive hormones. Rwanda J Med Health Sci 2020;3(3):315-328


2019 ◽  
Vol 6 (4) ◽  
pp. 1220
Author(s):  
Uma Maheswara R. Golamari ◽  
Meenakshi Sundari Subramaniyan Natarajan ◽  
Annam Lakshmanan ◽  
Rajeswari K. Balakrishnan

Background:  The aim of this study was to determine as well as to compare the salivary glucose levels in the diabetic and non-diabetic population and correlate the values with their fasting blood glucose and HbA1c (glycated Haemoglobin) levels. Many researchers have proposed the possibility of using salivary glucose estimation for screening and monitoring of effect in general population and in resource poor settings. But studies on this subject in Indian population are limited.Methods: The current study was an analytical cross sectional study of a group of 100 diabetic patients and 100 healthy controls, conducted in the Department of General Medicine, SRM medical college hospital. The mean difference in the salivary glucose between diabetic and non-diabetic population was compared using unpaired t-test.Results: There was a strong positive association between FBS (fasting blood sugar) and salivary glucose in the overall population. There was a strong positive correlation between FBS and Salivary glucose in FBS <200. There was a moderate positive association between FBS and salivary glucose in people with FBS value between 200 to 300 mg/dl. There was a weak positive association between FBS and salivary glucose in people with FBS value >300 mg/dl, which was statistically not significant. There was a strong positive correlation between HbA1c and salivary glucose in the overall population.Conclusions: There appears to be a strong positive association between fasting blood sugar and salivary glucose value in both study groups. But the correlation seems to be relatively weak in fasting blood sugar range above 300 mg/dl. Considering this positive association, further studies are needed to explore the possibility of utilizing salivary glucose for monitoring glycemic control.


Sign in / Sign up

Export Citation Format

Share Document