scholarly journals Association of metabolic syndrome in patients of vitiligo

2021 ◽  
Vol 7 (4) ◽  
pp. 337-340
Author(s):  
Yashdeep Jat ◽  
Krishnendra Varma ◽  
Ujjwal Kumar ◽  
Aishwarya Mahadik
Keyword(s):  
Metabolic Syndrome ◽  
Tertiary Care ◽  
Fasting Blood Glucose ◽  
Visceral Obesity ◽  
Serum Triglyceride ◽  
Clinical Feature ◽  
P Value ◽  
Serum Triglyceride Level ◽  
Care Hospital ◽  
The Metabolic Syndrome

The metabolic syndrome is the term used to describe a constellations of metabolic derangements that includes insulin resistance, hypertension, Dyslipidemia, central or visceral obesity, type 2 DM & accelerated cardiovascular disease. An oxidative imbalance is responsible for the development of both metabolic syndrome & vitiligo. In the present study we have evaluated the association of metabolic syndrome with Vitiligo.In this observational cross-sectional study we selected 40 subjects attending skin OPD with age matched 40 controls and assessed the waist circumference, blood pressure, serum triglyceride level, cholesterol and high-density cholesterol along with Fasting blood glucose level at tertiary care Hospital. A detailed history including age, gender, diabetes mellitus, hypertension, smoking and onset of vitiligo was taken. The MetS criteria were defined by National Cholesterol Education Program Adult Treatment Panel III 2005 (ATP III) guidelines.We identified metabolic syndrome in 15 subjects with vitiligo and 6 subjects without vitiligo. The P value came 0.022 which is statistically significant. Active vitiligo, segmental vitiligo and increased duration of vitiligo were determined to be independent predictors of metabolic syndrome.The risk of developing metabolic syndrome is increased in patients of vitiligo. Screening and the close follow up of the patients of vitiligo with clinical feature such as in unstable, segmental vitiligo with increased duration is necessary for the early diagnosis of the metabolic syndrome to reduce the morbidity & mortality of the patients

Prevalence of the Metabolic Syndrome in Schizophrenic Patients Receiving Second-Generation Antipsychotic Agents—A Cross-Sectional Study

2012 ◽  
Vol 25 (3) ◽  
pp. 368-373 ◽  
Author(s):  
Urmila A. Kagal ◽  
Shashikant S. Torgal ◽  
Nanasaheb M. Patil ◽  
Anil Malleshappa
Keyword(s):  
Metabolic Syndrome ◽  
Second Generation ◽  
Tertiary Care ◽  
Fasting Blood Glucose ◽  
Antipsychotic Agents ◽  
Care Hospital ◽  
Cross Sectional ◽  
The Metabolic Syndrome ◽  
Schizophrenic Patients ◽  
Second Generation Antipsychotic

Objective: The present study was taken up to assess the prevalence of the metabolic syndrome in schizophrenic patients receiving second-generation antipsychotic agents and to determine the most sensitive and specific clinical parameters used for screening of metabolic syndrome in these patients. Materials and Methods: The present study was taken up in a tertiary care hospital. Eighty patients diagnosed with schizophrenia and receiving a single second-generation antipsychotic for 3 months or more were enrolled in the study after obtaining written informed consent. Patients were screened for metabolic syndrome using American Heart Association and National, Heart, Lung and Blood Institute (AHA NHLBI)-modified National Cholesterol Education Program, Adult Treatment Panel III (NCEP ATP III) criteria. Results: Prevalence of metabolic syndrome was found to be 35%. The clinical parameter with highest sensitivity for screening of metabolic syndrome is low-serum high-density lipoprotein cholesterol with a sensitivity of 89.28%. Elevated fasting blood glucose and increased waist circumference were found to have highest and equal specificity of 90.38%. Conclusion: There is a high prevalence of the metabolic syndrome in patients with schizophrenic patients receiving second-generation antipsychotic agents. Increasing awareness of this fact among psychiatrists will help to prevent, detect, and treat this condition that is associated with considerable morbidity and mortality.

scholarly journals Metabolic syndrome in patients with chronic plaque psoriatic disease: a case-control study from western Uttar Pradesh, India

2018 ◽  
Vol 6 (2) ◽  
pp. 688
Author(s):  
Shailendra Jain ◽  
Preeti Jain ◽  
Abhishek Singh ◽  
Shewtank Goel
Keyword(s):  
Metabolic Syndrome ◽  
Venous Blood ◽  
Serum Triglyceride ◽  
Uttar Pradesh ◽  
Hdl Cholesterol ◽  
Serum Glucose ◽  
P Value ◽  
Serum Triglyceride Level ◽  
General Physical Examination ◽  
Psoriatic Disease

Background: Various studies on psoriasis and metabolic syndrome have shown a large variation in their results. An increasing frequency is imposing a substantial burden on the overall health of psoriasis patients that needs to be appropriately foreseen and addressed. Aim of this study was to study various aspects of metabolic syndrome in patients with chronic plaque psoriatic disease in northern Indian region.Methods: A cohort of patients registering for treatment of chronic plaque psoriasis at Dermatology outpatients’ department formed the study population. Detailed history was captured. General physical examination was carried out. A thorough cutaneous examination was undertaken which captured details on type, distribution and arrangement of primary lesions and secondary changes in patients. After overnight fasting, venous blood samples were collected from the subjects and were analysed for serum glucose, triglyceride and HDL-cholesterol. Results: Metabolic syndrome in psoriasis was associated with higher age. Gender wise male preponderance was observed. Among the psoriasis cases, 64% had metabolic syndrome whereas among the control subjects 48% had the condition (p-value 0.158). The mean for serum triglyceride level for psoriasis patients (159.42 mg/dL) was higher than controls (144.25 mg/dL). Forty six percent of cases fulfilled elevated triglycerides ≥150 mg/dl as a criterion of metabolic syndrome, compared to 40% of controls. Conclusions: We observed a higher frequency of metabolic syndrome among psoriasis cases in a northern Indian population. An association of dyslipidemia with psoriasis was also noted. Routine screening of the condition to facilitate early diagnosis and treatment should be undertaken.

scholarly journals Prevalence of different components of the metabolic syndrome in type 2 diabetics attending tertiary care hospital in Himalayan region

2017 ◽  
Vol 5 (12) ◽  
pp. 5232
Author(s):  
Vikram Singh ◽  
Mridu Singh ◽  
Anil Joshi ◽  
Chitra Joshi
Keyword(s):  
Metabolic Syndrome ◽  
Tertiary Care ◽  
International Diabetes Federation ◽  
Diabetic Patients ◽  
Care Hospital ◽  
The Metabolic Syndrome ◽  
Type 2 Diabetics ◽  
Hilly Region ◽  
Prevalence Of Obesity

Background: There are enormous studies on various aspect of Diabetes and Metabolic syndrome, majority of studies are on urban population, few in rural area but very few for the population living in far flung hilly region of Himalaya. The aim was to find the prevalence of different components of metabolic syndrome in Type 2 diabetics living in the hills of Himalaya and to find correlation with obesity.Methods: All the Type 2 Diabetic patients age 35 years and above attending the inpatients and out patient’s department of V. C. S. G. G. M. C and RI Srinagar, Uttarakhand from October 2012 to March 2013 were enrolled and were evaluated for metabolic syndrome by IDF (International Diabetes Federation) criteria.Results: 128 diabetics were enrolled (76 males and 52 females), the prevalence of obesity in patients of type 2 diabetics was 45.3%. There was poor correlation between obesity and type 2 diabetes (correlation coefficient 0.08) The prevalence of metabolic syndrome was 40.6 % and high percentage (62%) had all five components of the syndrome.Conclusions: The prevalence of obesity and Metabolic syndrome is relatively lower in Type 2 Diabetics of Shivalik range of Himalaya (Uttarakhand).

scholarly journals Age and Gender Differences of Metabolic Factors among the Essential Hypertension Patients at a Tertiary Care Hospital in Dhaka

2016 ◽  
Vol 12 (2) ◽  
pp. 34-38
Author(s):  
Md. Akhtaruzzaman ◽  
Md. Nazibur Rahman Khandaker ◽  
Fatema Akhter Banu ◽  
Gobinda Chandra Saha ◽  
Md. Abdullah Yusuf ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Essential Hypertension ◽  
Waist Circumference ◽  
Tertiary Care ◽  
Care Hospital ◽  
Metabolic Factors ◽  
College Hospital ◽  
Hypertensive Patients ◽  
The Metabolic Syndrome ◽  
Increased Risk

Background: Metabolic syndrome is a risk factor for cardiovascular disease. Objectives: The purpose of the present study was to see the association of metabolic syndrome with essential hypertension. Methodology: This cross sectional study was carried out in the OPD of the Department of Cardiology at Shaheed Suhrawardy Medical college Hospital, Dhaka from January 2008 to December 2010. All the All the Metabolic syndrome was defined as abnormal fasting serum level of glucose (? 110 mg/dl or 6.1 mmol/L) with abdominal obesity (waist circumference > 102 cm in men and > 88cm in women), triglycerides (? 150mg/dl), High density lipoprotein cholesterol (< 40 mg/dl in men and < 50 mg/dl in women) and hypertension. Results: . A total of 322 patients were enrolled Among hypertensive patients 31.8% had hyperglycemia, 37.9% had high waist circumference, 69.8% had low HDL cholesterol and 54.3% high triglycerides. As per definition of NCEP-ATP-III, metabolic syndrome had been detected in 17% of male, 37% of female and 27% of total population. Conclusion: Metabolic factors are a common association in hypertensive cases. These patients are at increased risk of coronary and cerebro-vascular disease and require more vigorous prevention. Furthermore in all hypertensive patients metabolic screening is recommended.Journal of Science Foundation 2014;12(2): 34-38DOI: http://dx.doi.org/10.3329/jsf.v12i2.27736

Effect and Mechanism of Virechana Karma (Therapeutic Purgation) Over Fructose-Induced Metabolic Syndrome

2015 ◽  
Vol 21 (3) ◽  
pp. 194-201 ◽  
Author(s):  
Ashutosh Chaturvedi ◽  
Prasanna N. Rao ◽  
M. Ashvini Kumar ◽  
B. Ravishankar ◽  
Niranjan Rao ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Fasting Blood Glucose ◽  
Animal Experiments ◽  
Serum Triglyceride ◽  
Positive Control ◽  
The Body ◽  
Control Group ◽  
Albino Rats ◽  
The Metabolic Syndrome ◽  
Obesity And Diabetes

Background. Panchakarma (biopurification methods) is one of the modes of ayurveda to treat disorders of the body. Virechana karma (therapeutic purgation), one among the Panchakarma, is a purification process that is commonly used to treat metabolic disorders like obesity and diabetes mellitus. Hence this study was planned to provide evidence through animal experiments. Methods. Albino rats were subject to Virechana karma (therapeutic purgation) to evaluate the influence of therapy and its mechanism over fructose-induced metabolic syndrome. Results. Results show that Virechana is effective in the management of the metabolic syndrome with decrease in the fecal fat content, fasting blood glucose, serum triglyceride, and reduced fatty changes in liver, heart, and kidney in comparison with the positive control group. Conclusion. Experimental evaluation showed decrease in fatty acid in the storage like liver, kidney, heart, and muscle adipose tissue can indirectly increase the insulin sensitivity in insulin receptor present at skeletal muscles.

scholarly journals An observational study of the evaluation of fatty liver in non-alcoholics with metabolic syndrome using fatty liver index and its correlation with USG elastography

2020 ◽  
Vol 7 (4) ◽  
pp. 673
Author(s):  
Vaishnavi Danasekaran ◽  
M. Narayanan
Keyword(s):  
Metabolic Syndrome ◽  
Liver Disease ◽  
Waist Circumference ◽  
Fatty Liver ◽  
Tertiary Care ◽  
P Value ◽  
Care Hospital ◽  
Alcoholic Fatty Liver ◽  
Liver Index ◽  
Fatty Liver Index

Background: NAFLD (Non Alcoholic Fatty Liver Disease) is being considered the hepatic component of metabolic syndrome. It is now the most common cause of chronic liver disease worldwide and needs to be addressed urgently as it is asymptomatic and widely prevalent and can progress to cirrhosis and hepatocellular carcinoma. There is a need for simpler methods to diagnose the condition in modern day practice which will help in identifying vulnerable subjects and in bringing  about awareness and lifestyle modifications focused on reversal of the condition. Aim of this study was to check the applicability of the fatty liver index in modern day out patient practice using formula based FLI calculator.Methods: It was a cross sectional study on patients with metabolic syndrome in a tertiary care hospital. 60 patients with metabolic syndrome, both male and female above the age of 30 years and who were non-alcoholics were enrolled in the study. BMI, waist circumference, lipid profile and GGT were obtained and FLI calculated. It was compared with the ultrasound and Elastography reports. Chi square test, Independent t test and ANOVA test were used for comparing parameters. A p value of <0.05 was considered statistically significant.Results: Among 60 patients all had fatty liver which emphasizes that fatty liver is the hepatic component of metabolic syndrome. There is a significant correlation between BMI (Body Mass Index) and waist circumference in predicting fatty liver and to some extent its grade. Patients with higher BMI had a greater grade of fatty liver.Conclusions: The fatty liver index is a reliable predictor of fatty liver in people with metabolic syndrome. The grade of fatty liver increases with increase in waist circumference and increased BMI. Ultrasound and Elastography are reliable non invasive methods of detecting fatty liver. BMI and Waist circumference are strong predictive factors for fatty liver.

scholarly journals Prevalence of metabolic syndrome in psoriasis vulgaris: a cross sectional study from a tertiary care hospital of South-East Rajasthan

2016 ◽  
Vol 2 (2) ◽  
pp. 30
Author(s):  
Manjaree Morgaonkar ◽  
Ramesh Kushwaha ◽  
Savera Gupta ◽  
Suresh Kumar Jain ◽  
Dattatray V. Kulkarni ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Psoriasis Vulgaris ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
P Value ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
Systemic Inflammatory Disease ◽  
Significant Difference

<p class="abstract"><strong>Background:</strong> Psoriasis, a common skin disorder is now considered as systemic inflammatory disease. Its chronic inflammatory state is thought to predispose patients to metabolic syndrome (MetS), which is a significant predictor of cardiovascular events. The objective of the study is to investigate the prevalence of metabolic syndrome in psoriatic patients with only cutaneous involvement and to evaluate the correlation between presence of MetS and psoriasis severity</p><p class="abstract"><strong>Methods:</strong> We performed hospital based, cross-sectional study on 100 adult patients with psoriasis vulgaris and equi-numbered age and sex matched controls. MetS was diagnosed by revised National Cholesterol Education Program’s Adult Panel III criteria.</p><p class="abstract"><strong>Results:</strong> A higher prevalence of metabolic syndrome was found in psoriasis patients as compared to controls [28 (28%) vs 9 (9%), P value=0.0005].Impaired fasting glucose level, hypertension, hypertriglyceridemia and abdominal obesity were more prevalent in psoriasis group. No statistically significant difference was found between prevalence of low levels of HDL and presence of metabolic syndrome. Presence of metabolic syndrome was not associated with severity and duration of psoriasis. Female patients with psoriasis were more frequently having metabolic syndrome.</p><strong>Conclusions:</strong> Prevalence of metabolic syndrome is higher in patients with psoriasis irrespective of its duration and severity. This stresses on the need of regular evaluation for the presence of MetS or any of its components in psoriasis patients so as to allow early detection and management.

scholarly journals Evaluation of vitamin D status in suspected cases of metabolic syndrome

2019 ◽  
Vol 7 (5) ◽  
pp. 1515
Author(s):  
Radhika Krishnaswamy ◽  
Shelomith K. Chawang ◽  
Priyadharshini Krishnaswamy
Keyword(s):  
Metabolic Syndrome ◽  
Vitamin D ◽  
Tertiary Care ◽  
Fasting Blood Glucose ◽  
Age Groups ◽  
Serum Vitamin ◽  
Care Hospital ◽  
Serum Vitamin D ◽  
Increased Risk ◽  
Vitamin D Levels

Background: Metabolic syndrome is associated with an increased risk of cardiovascular disease and type 2 diabetes mellitus. Vitamin D has been linked to glucose metabolism and insulin regulation. Hence, this study aims to evaluate the association between the serum level of vitamin D and metabolic syndrome. This may help generate additive strategies in the prevention and management of this syndrome. The objective of the study was to compare the levels of serum vitamin D in subjects with metabolic syndrome and subjects without metabolic syndrome.Methods: A prospective study with 80 subjects was conducted at a tertiary care hospital in Southern India. The sample comprised 40 subjects in the age group of (18-60 years) with metabolic syndrome as cases and 40 subjects without metabolic syndrome in the age groups of (18-60 years) as controls. The presence of any 3 of the following- fasting blood glucose (FBS ≥100mg/dl), triglycerides (TGL≥150mg/dl) and high-density lipoprotein cholesterol (HDL-C ≤40mg/dl-men, ≤50mg/dl-women) levels, blood pressure (≥130/85mmHg or drug treatment) and abdominal waist circumference (>94 cm (37 in) in men and >80 cm (31 in) in women) were used as criteria to screen for the presence (cases) or absence (controls) of metabolic syndrome. Serum vitamin D (25-hydroxy vitamin D) levels were compared between the two groups.Results: Mann Whitney U test was used to compare the vitamin D levels between the two groups. Significantly (p=0.05) lower vitamin D levels were seen in the cases compared to the controls.Conclusions: Metabolic syndrome is associated with significantly lower serum vitamin D levels. We suggest that further studies with a larger sample size be undertaken to confirm the same.

scholarly journals CASE STUDY: WEIGHT LOSS CAUSES IMPROVEMENT IN METABOLIC SYNDROME AND COST EFFECTIVE

2013 ◽  
Vol 2 (2) ◽  
pp. 45-47
Author(s):  
Muhammad Sarfraz ◽  
Erum Naz ◽  
Arham Shamsi ◽  
Syeda Amool Sakeena Rizvi ◽  
Roomi Ilyas
Keyword(s):  
Metabolic Syndrome ◽  
Weight Loss ◽  
Tertiary Care Hospital ◽  
Physical Therapist ◽  
Tertiary Care ◽  
Severe Depression ◽  
Care Hospital ◽  
The Metabolic Syndrome ◽  
Supervised Exercise ◽  
Diet Plan

A case report study conducted in a tertiary care hospital to determine the effectiveness of supervised exercise diet plan along with behavioral therapy to reduce weight in the metabolic syndrome. A 54 years old obese male was selected to conduct the study that suffering from diabetes for last 10 years, hypertensive previous 13 years, knee osteoarthritis previous 8 years back and also has complaint of dyspnea as a result facing severe problems in his ADL. He was on 8 different medications when he visited a Physiotherapy OPD in a tertiary care hospital by his consultant to secure his health status. He was than enrolled in fitness program to reduce weight under supervision of a physical therapist. According to his lab reports he was highly on health risk and was going in severe depression due to the difficulty facing in his daily life. The out measures of our study was Visual Analogue scale, Exercise and diet plan with counseling sessions, after 16 weeks supervised exercise diet plan and counseling sessions we observe a marked improvement in glucose tolerance, exercise tolerance, lipid profile and hypertension. The patient was following exercise plan for 5days/week and diet plan throughout the month with a single counseling session in a week with marked reduction in medications. Our study concludes that the medically supervised weight-loss program facilitates is safe and effective in weight

scholarly journals Clinic epidemiological evaluation of co morbidities in patients with psoriasis in a tertiary care hospital

2021 ◽  
Vol 8 (3) ◽  
pp. 8-12
Author(s):  
Jaffer basha SK
Keyword(s):  
Diabetes Mellitus ◽  
Metabolic Syndrome ◽  
Waist Circumference ◽  
Tertiary Care ◽  
Control Group ◽  
P Value ◽  
Common Disease ◽  
Care Hospital ◽  
P Values ◽  
Significant Difference

Background: Psoriasis is a common disease presented to the dermatology clinics. There are several reports concerning co morbidities in patients with psoriasis. Some of them include diabetes mellitus, hypertension, dyslipidemia, obesity, IHD, ulcerative colitis. Hence, we in the present study tried to evaluate the existing comorbidities in patients diagnosed with psoriasis in presenting to our hospital. Methods: This study was conducted in the Department of Dermatology, Venereology, and Leprosy, Prathima Institute of Medical Sciences, Karimnagar. This case-control study evaluated the prevalence of diabetes mellitus, hypertension, obesity, dyslipidemia and metabolic syndrome in patients with psoriasis. The existence of hypertension, diabetes mellitus, dyslipidemia, obesity was determined by standard criteria. The data was recorded and analyzed using SPSS version 17 for p values. Results: BSL (Blood Sugar Level) derangement as increased fasting BSL was observed in 23 (23%) cases compared to 8(8%) controls. There was a statistically significant difference between psoriatic cases and controls. The total number of male patients with raised waist circumference was 24 (33.8%) compared to 9(13.2%) controls. There was a statistically significant association of raised waist circumference in psoriasis cases compared to controls, the p-value was <0.004. The existence of metabolic syndrome was 27% in the study group and 8% in the control group the p values were <0.004 and significant. Conclusion: The results of the present shows that there is a significant prevalence of psoriasis in males as compared to females. There is a significant association of metabolic syndrome in patients with psoriasis. Hence all the patients with psoriasis need to be evaluated for metabolic syndrome which may be a risk factor for systemic diseases.

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