scholarly journals An Innovation for Retarded Healing Process of a Chronic Ulcer by Aloe Vera Gel Treatment

2016 ◽  
Vol 16 (2) ◽  
pp. 45 ◽  
Author(s):  
Majid Avijgan ◽  
Mahtab Avijgan ◽  
Atousa Hakamifard ◽  
Niloufar Razavi
Keyword(s):  
Potassium Permanganate ◽  
Conventional Treatment ◽  
Healing Process ◽  
Aloe Vera ◽  
Complete Healing ◽  
Response To Therapy ◽  
Chronic Ulcer ◽  
Alternative Methods ◽  
Aloe Vera Gel ◽  
Gel Treatment

In some cases of chronic ulcers of soft tissue cannot be treated by conventional treatment methods. In recent years some alternative methods have been proposed for treatment of such ulcers on the basis of Traditional Iranian (Persian) Medicine. This reports a case of chronic ulcer treatment by using <em>Aloe vera</em> gel. The ulcer was caused by car accident and in spite of using conventional treatment the injury remained for 60 days without appropriate response to therapy. Because of stopping in healing process by Aloe vera gel, this was discontinued and potassium permanganate has been used. After drying the ulcer using the alternative method of <em>Aloe vera</em> gel and potassium permanganate together has been applied and then the <em>Aloe vera</em> gel was used until the complete healing of ulcer. The delayed healing process of <em>Aloe vera</em> gel raise the question whether it is solely effective in complete healing of chronic ulcer or requires adjuvant therapies. Although <em>Aloe vera</em> is effective in healing process of chronic ulcer but sometimes it may be ineffective so that we are obliged to use potassium permanganate as an adjuvant drug which is presented by this case report.

scholarly journals The therapeutic efficacy of Aloe vera gel ointment on staphylococcal pyoderma in dogs

2020 ◽  
Vol 13 (11) ◽  
pp. 2371-2380
Author(s):  
Ahmed Kamr ◽  
Ali Arbaga ◽  
Amanallah El-Bahrawy ◽  
Ahmed Elsify ◽  
Hadeer Khaled ◽  
...  
Keyword(s):  
Therapeutic Efficacy ◽  
Aloe Vera ◽  
Inhibition Zone ◽  
Complete Healing ◽  
Aloe Barbadensis ◽  
Local Breed ◽  
Aloe Vera Gel ◽  
Antioxidant Parameters ◽  
Anti Inflammatory ◽  
Factor Α

Background and Aim: Staphylococcus pyoderma is a common problem in dogs that need a novel treatment rather than antibiotic therapy. The aim of this study was to investigate the therapeutic efficacy, anti-inflammatory, and antioxidative properties of Aloe vera (Aloe barbadensis) gel ointment on dogs' Staphylococcus pyoderma compared to gentamicin ointment. Materials and Methods: The inhibition zone of A. vera extract 20% and 40% and gentamicin 1% against Staphylococcus aureus was determined on well diffusion agar. Twenty Baladi local breed dogs were used as control negative group before intradermal inoculation with 105 CFU S. aureus. The animals were classified into four equal groups, control positive group without treatment (n=5), treated groups by 20% A. vera gel ointment (n=5), 40% A. vera gel ointment (n=5), and gentamicin ointment 1% (n=5). Topical application of A. vera and gentamicin ointments was carried out twice daily for 2 weeks until complete healing of dogs' pyoderma. Clinical evaluation was recorded. Inflammatory, oxidant, and antioxidant parameters were measured in serum. Results: The inhibition zone of A. vera extracts 20% and 40% was 19 mm and 23 mm, respectively, while gentamicin 1% was 18 mm. The half maximal inhibitory concentration (of A. vera 20% and 40% were 13.70 with R2=0.98. Dogs' pyoderma treated with A. vera gel ointment 20% and 40% were more likely to have low haptoglobin and tumor necrosis factor-α concentrations than gentamicin 1% ([odds ratio [OR]=4.6; 95% confidence interval [CI]=1.31-17.40; p<0.05]; [OR=5.2; 95% CI=1.04-22.30; p<0.05]), respectively. Conclusion: It seems evident that A. vera has therapeutic effect, antibacterial, and anti-inflammatory effects against dogs' staphylococcal pyoderma than gentamicin that would support its further use rather than antibiotics in one health arena.

scholarly journals Comparison of TGF-β1 in corneal laceration with or without Aloe vera gel treatment

2021 ◽  
Vol 11 (1) ◽  
pp. 120-124
Author(s):  
Nur Atik ◽  
Muhamad Arif Rachman Sururi ◽  
Raden Angga Kartiwa
Keyword(s):  
Aloe Vera ◽  
Aloe Vera Gel ◽  
Gel Treatment ◽  
Tgf Β1 ◽  
Corneal Laceration

Processed Aloe vera gel attenuates non-steroidal anti-inflammatory drug (NSAID)-induced small intestinal injury by enhancing mucin expression

2019 ◽  
Vol 10 (9) ◽  
pp. 6088-6097 ◽  
Author(s):  
Min Woo Kim ◽  
Ju-Hee Kang ◽  
Eunju Shin ◽  
Kyu-Suk Shim ◽  
Min Jung Kim ◽  
...  
Keyword(s):  
Adverse Effects ◽  
Aloe Vera ◽  
Intestinal Damage ◽  
Inflammatory Drug ◽  
Aloe Vera Gel ◽  
Small Intestinal Injury ◽  
Mucin Expression ◽  
Gel Treatment ◽  
Small Intestinal ◽  
Potential Strategy

NSAIDs-induced intestinal damage is one of the most common adverse effects by medication. Here, we suggest processed Aloe vera gel treatment as a potential strategy to attenuate NSAID-induced intestinal damage via enhancing mucin expression.

Evaluating the Properties of an Alginate Wound Dressing for Skin Repair

2013 ◽  
Vol 683 ◽  
pp. 141-144 ◽  
Author(s):  
Rúben Pereira ◽  
Ausenda Mendes ◽  
Paulo J. Bártolo
Keyword(s):  
Wound Dressing ◽  
Healing Process ◽  
Aloe Vera ◽  
Skin Lesions ◽  
Synthetic Drugs ◽  
Skin Repair ◽  
Complex Process ◽  
Aloe Vera Gel ◽  
Therapeutic Properties ◽  
Calcium Alginate Gels

The treatment of skin lesions is a costly and complex process, for which different strategies are currently available. In this study, we investigated the properties of novel films composed of alginate and aloe vera gel for application as wound dressing material. The films combine the occlusive and haemostatic properties of calcium alginate gels with the therapeutic properties of aloe vera. We expect that these films may improve the healing process through the release of aloe vera compounds directly into the wound bed and could be an alternative to the administration of synthetic drugs to infected wounds. The films exhibited high transparency in both dry and wet state, as well as adequate mechanical properties for skin use. The results indicated that the films present great potential to be explored as wound dressing material.

Influence of Aloe Vera Gel on Dermal Wound Healing Process in Rat

2008 ◽  
Vol 19 (1) ◽  
pp. 73-77 ◽  
Author(s):  
Nasrin Takzare ◽  
Mir-jamal Hosseini ◽  
Gholamreza Hasanzadeh ◽  
Hamideh Mortazavi ◽  
Alireza Takzare ◽  
...  
Keyword(s):  
Wound Healing ◽  
Healing Process ◽  
Aloe Vera ◽  
Wound Healing Process ◽  
Dermal Wound Healing ◽  
Aloe Vera Gel ◽  
Dermal Wound

Effect of Aloe vera gel treatment on bioactive compounds and antioxidant activity during storage of sweet cherry

2017 ◽  
pp. 607-612 ◽  
Author(s):  
M. Serrano ◽  
S. Castillo ◽  
D. Valero ◽  
J.M. Valverde ◽  
F. Guillén ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Bioactive Compounds ◽  
Sweet Cherry ◽  
Aloe Vera ◽  
Aloe Vera Gel ◽  
Gel Treatment

scholarly journals Chitosan and Aloe vera gel formulations as wound healing agents in episiotomy

2021 ◽  
Vol 10 (6) ◽  
pp. e36310614895
Author(s):  
Maria Dennise Medeiros Macêdo ◽  
Hiago Kartney Belarmino Dantas ◽  
Matheus Ferreira de Souza ◽  
Thiago Cajú Pedrosa ◽  
Ana Caroline Santana de Azevedo ◽  
...  
Keyword(s):  
Healing Process ◽  
Aloe Vera ◽  
Biological Properties ◽  
Attractive Alternative ◽  
Aloe Vera Gel ◽  
Vaginal Gels ◽  
Perineal Region ◽  
Pass Through ◽  
Gel Formulations ◽  
Chitosan Gel

Episiotomy is an obstetric technique that consists of making an incision in the perineum during vaginal childbirth, to facilitate the baby to pass through. After delivery, the perineal region is sutured with absorbable threads to heal the cut. However, are frequent reports of pain, infections, and dyspareunia after the execution of this technique. In this context, the use of biomaterials becomes relevant as they promote faster and safer tissue repair, making it an attractive alternative for the healing process of episiotomy. Based on the physical-chemical and biological properties of chitosan and Aloe vera, this research developed three different vaginal gels, with the purpose of promoting tissue regeneration and infection prevention post-episiotomy. Chitosan solutions with concentrations of 5% w/v were prepared by dissolving the chitosan powder in 2% v/v aqueous solution of acetic acid. After the extraction and processing of the mucilage, the pulp of the Aloe vera leaf was added to the chitosan gel in the proportions of 1, 2, and 3% v/v. All formulations were neutralized by the slow drip technique of a neutralizing solution of sodium hydroxide (2 M). The compositions were analyzed according to their organoleptic aspect, optical microscopy, spreadability, hydrogen potential, absorption spectroscopy, cytotoxicity, and rheological behavior. Based on the results obtained, it was possible to conclude that gels produced have the potential to be used as vaginal gels.

scholarly journals The effectiveness of aloe vera gel in reducing the pain of perineal wound

MEDISAINS ◽  
2020 ◽  
Vol 18 (3) ◽  
pp. 99
Author(s):  
Putri Sitronela Dewi ◽  
Umu Hani ◽  
Mochamad Anwar
Keyword(s):  
Post Partum ◽  
Aloe Vera ◽  
Sampling Technique ◽  
Perineal Wound ◽  
Pain Scale ◽  
Perineal Pain ◽  
Aloe Vera Gel ◽  
Significant Difference ◽  
Gel Treatment ◽  
Wound Pain

Background: Researches on applying ice gel and aloe vera gel compress to reduce perineal wound pain scale after childbirth has been widely studied and proven effective. However,  the effectiveness of using both has not been studied.Objective: The purpose of this study was to determine the effectiveness differences of ice gel and aloe vera gel in reducing the intensity of perineal wound pain.Methods: It applied a quasi-experimental research design. The population was 116 post-partum mothers, a sample of 56 mothers with sutured perineal wounds grade II, divided into two groups of intervention (aloe vera gel compress) and control (ice gel compress), with a consecutive sampling technique. The pain before and after the intervention was observed and analyzed using the Wilcoxon and Maan Whitney tests.Result: The mean reduction in pain scale in the group with the aloe vera gel treatment was more than that in another group with ice gel treatment, with a mean difference of 2.46 and 1.61. The statistical analysis results showed a significant difference in pain relief between the two groups, p<0.05.Conclusion: The aloe vera gel compresses are more effective than the ice gel compresses in reducing the scale of perineal pain after childbirth.

Transforming growth factor-β (TGF-β) activation in cutaneous wounds after topical application of aloe vera gel

2016 ◽  
Vol 94 (12) ◽  
pp. 1285-1290 ◽  
Author(s):  
Nasrin Takzaree ◽  
Abbas Hadjiakhondi ◽  
Gholamreza Hassanzadeh ◽  
Mohammad Reza Rouini ◽  
Azadeh Manayi ◽  
...  
Keyword(s):  
Gene Expression ◽  
Wound Healing ◽  
Transforming Growth Factor ◽  
Skin Diseases ◽  
Healing Process ◽  
Aloe Vera ◽  
Cell Counting ◽  
Control Group ◽  
Aloe Vera Gel ◽  
Experimental Group

Aloe vera is a medicinal plant used to treat various skin diseases. The effects of using aloe vera gel on the healing process were investigated by microscopic methods, cell counting, and TGF-β gene expression in the wound bed. Sixty Wistar rats weighing 200–250 g were placed under anesthesia in sterile conditions. A square 1.5 cm × 1.5 cm wound was made on the back of the neck. The rats were divided into control and 2 experimental groups. Additionally, the control and experimental groups were separated into 3 subgroups corresponding to 4, 7, and 14 days of study. In the first experimental group, aloe vera was used twice on the wound. The second experimental group received aloe vera overtreatment once on the wound. The positive control group received daily application of 1% phenytoein cream following surgical wound creation. The control group did not receive any treatment. This tissue was examined using histological staining (H&E) and Masson’s Trichrome. Wound surface and wound healing were evaluated separately. TGF-β gene expression was analyzed by RT–PCR. Results showed that fibroblasts in both experimental groups were significantly increased, thereby acceleration wound healing. Application of aloe vera gel will increase TGF-β gene expression, ultimately accelerating the wound healing process.

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