scholarly journals Effectiveness of Pre PRP Injection and Post Elevation Flap at Extended Random Flap Rat Skin

2021 ◽  
Vol 56 (3) ◽  
pp. 186
Author(s):  
Thomas Eduardus Sudrajat Wahyu Nugroho ◽  
Sitti Rizaliyana ◽  
David S Perdanakusuma

Background:Closure of the defect with a random skin flap is constrained by the extent of the defect area. Several studies have shown the benefits of administration of PRP (Platelet Rich Plasma) in random skin flap. The purpose of this study is to compare the effect of PRP injection given before flap elevation, after flap elevation and control on the extended random skin flap procedures in rats.Methods: This research is experimental with randomized post test only control group design (n = 27, divided into 3 treatment groups) that compare the effectiveness of PRP injection 24 hours prior to the elevation of the flap, after the elevation of the flap, and control in the extended random skin flap in rats. Random skin flap is made in the ratio 1: 5 on the rat skin. Measurement of viable area were observed on days 1, 7 and 14.Results: There were significantly increased viability of random skin flap on the group with PRP injection 24 hours prior flap elevation compared to other group of treatment. The average of viability on day first 39%±13% ;42%±34%; 62%±14%. On day 7th24%±13%; 36%±26%; 62%±12%.On day 14th16%±15%; 28%±22%; 60%±11%.Conclusion: Injection of PRP on extended random skin flap on rat 24 hours before flap elevationincrease viability of the flap compared to control group and group which receive PRP injection on extended random flap on rat skin after elevation of the flap. Viability increased due to angiogenesis stimulation after PRP injection.

2020 ◽  
Vol 56 (3) ◽  
pp. 186
Author(s):  
Thomas Eduardus Sudrajat Wahyu Nugroho ◽  
Sitti Rizaliyana ◽  
David S Perdanakusuma

Closure of the defect with a random skin flap is constrained by the extent of the defect area. Several studies have shown the benefits of administration of PRP (Platelet Rich Plasma) in random skin flap. The purpose of this study is to compare the effect of PRP injection given before flap elevation, after flap elevation and control on the extended random skin flap procedures in rats. This was an experimental study with randomized posttest-only control group design (n=27, divided into 3 treatment groups) that compare the effectiveness of PRP injection 24 hours prior to the elevation of the flap, after the elevation of the flap, and control in the extended random skin flap in rats. Random skin flap is made in the ratio 1: 5 on the rat skin. Measurement of viable area were observed on days 1, 7 and 14. There were significantly increased viability of random skin flap on the group with PRP injection 24 hours prior flap elevation compared to other group of treatment. The average of viability on day first 39%±13% ;42%±34%; 62%±14%. On day 7th 24%±13%; 36%±26%; 62%±12%. On day 14th 16%±15%; 28%±22%; 60%±11%. Injection of PRP on extended random skin flap on rat 24 hours before flap elevation increase viability of the flap compared to control group and group which receive PRP injection on extended random flap on rat skin after elevation of the flap. Viability increased due to angiogenesis stimulation after PRP injection.


2016 ◽  
Vol 3 (2) ◽  
pp. 101-106
Author(s):  
Anita Rahmawati

Father’s role strongly proved in increasing the success of breastfeeding process, but in realitymany fathers are still not implementing its role in the process of breastfeeding (breastfeeding father’srole) because of father’s education and the assumption of breastfeeding is mother’s responsibilities. Thepurpose of this study was to analyze the effect of the father prenatal education toward breastfeedingfather’s role. This study used post test only control group design. 30 samples were taken by purposivesampling which further divided into control and treatment groups by simple random. Breastfeedingfather’s role was measured by a questionnaire and the data were analyzed by independent t test. Theresults showed breastfeeding father’s role rate and standard deviation in the treatment group was 15.40± 2.558, while in the control group 9.80 ± 4.212. Different test treatment and control group obtained thevalue p = 0,000 which means there was a significant effect of education toward breastfeeding father’srole between the treatment group and the control group. The nurse recommended to educate pregnantwomen prenatal classes which was devoted to the father (husband) as an alternative solution to improvethe success of exclusive breastfeeding program.


2021 ◽  
Vol 9 (3) ◽  
pp. 712-719
Author(s):  
Ayşe Eliüşük Bülbül ◽  

The purpose of this study is to determine the effect of the "patience training program" on the patience and life satisfaction levels of university students. The study was organized as a pre-test, post-test experiment and control group design. For a total of 30 students from which were 17 in the control group and 17 in the experimental group, patience training was given for 5 weeks. The "Patient Scale" developed by Schnitker (2010) and adapted to Turkish by Eliüşük and Arslan (2016) and the "Life Satisfaction Scale" developed by Diener, Emmons, Larsen and Griffin (1985) and adapted to Turkish by Dağlı and Baysal (2016) were used as a data collection tool in the study. The "Wilcoxon" test was used for the comparison of in-group differences in the analysis of obtained data and the "Mann-Whitney U" test was used in examining the differences between the two groups. As a result of the study, it was observed that the patience and life satisfaction average scores of students in the experimental group receiving "patience training" increased significantly, while there was no significant difference in the patience and life satisfaction averages scores of the control group students.


2015 ◽  
Vol 5 (2) ◽  
pp. 90
Author(s):  
Olievia Prabandini Mulyana ◽  
Wayan Sukmawati Puspitadewi

This research is aimed to determine the effectivity of training to increase self-efficacy towards career preference options in psychology. This is a quantitative research, in which experiment method is applied by using pretest-posttest control group design. The dependent variable is self-efficacy towards career preference options in psychology. Self efficacy towards career preference options in psychology is measured using self efficacy towards career preference options scale. The independent variable in this research is career planning training. The research subject are 40 persons groupped into experiment group and control group. Pre-test are given to both experiment and control group. next, the experiment group is given treatment of career planning training. The next step, post test is administered to experiment group and control group. The research is analized using anava repeated measure. Anava repeated measure resulted showing significant result. Thus, hyphothesis stating that there is effect of career planning training to self efficacy towards career preference options for psychology student of UNESA is accepted. Self efficacy towards career preference options for psychology increased after career planning training is given as treatment. Self efficacy towards career preference options for psychology in experiment group between pre-test and post-test is different.Abstrak: Penelitian ini bertujuan untuk mengetahui efektivitas pelatihan dalam meningkatkan efikasi diri terhadap pilihan bidang minat karir psikologi. Jenis penelitian yang digunakan dalam penelitian ini adalah penelitian kuantitatif. Penelitian ini menggunakan metode eksperimen dengan desain eksperimen yang digunakan adalah pretest-posttest control group design. Variabel tergantung pada penelitian ini adalah efikasi diri terhadap pilihan bidang minat karir psikologi. Kemampuan efikasi diri terhadap pilihan bidang minat karir psikologi diukur dengan skala efikasi diri terhadap pilihan bidang minat karir. Sedangkan variabel bebas dalam penelitian ini adalah pelatihan perencanaan karir. Subjek penelitian yang berjumlah 40 orang yang kemudian dikelompokkan ke dalam kelompok eksperimen dan kelompok kontrol. Pada kelompok eksperimen dan kelompok kontrol diberikan pre-test. Selanjutnya pada kelompok eksperimen dikenai perlakuan berupa pelatihan perencanaan karir. Tahapan berikutnya adalah pemberian posttest pada kelompok eksprimen dan kelompok kontrol. Analisis yang akan digunakan adalah anava amatan ulangan. Hasil anava amatan ulangan menunjukkan hasil yang signifikan. Dengan demikian, hipotesis yang menyatakan bahwa ada pengaruh pelatihan perencanaan karir terhadap efikasi diri terkait pilihan minat bidang karir psikologi pada mahasiswa psikologi UNESA, diterima. Efikasi diri terhadap pilihan minat bidang karir di Psikologi meningkat setelah diberikan pelatihan perencanaan karir.


2019 ◽  
Vol 1 (2) ◽  
pp. 226-235
Author(s):  
Afnijar Wahyu ◽  
Liza Wati ◽  
Murad Fajri

The purpose of this study was to determine the effect of AIUEO therapy on the speech ability of stroke patients who have motor aphasia in Raja Ahmad Thabib Hospital Tanjungpinang. The research design used was quasi experiment with the Nonequivalent Control Group Design approach to 9 respondents who were divided into 9 treatment groups and 9 control groups. The results showed that there were significant differences in the functional ability of communication between the control and treatment groups with a value of p <0.05 (p = 0.007 at a = 0.05) using the Wilcoxon Test statistical test. Conclusion, the influence of AIUEO therapy on the speech ability of stroke patients with motor aphasia in the treatment and control groups at Ahmad Thabib Hospital Tanjungpinang.   Keywords: Speech Ability, Motor Aphasia Stroke, AIUEO Therapy


2019 ◽  
Vol 3 (1) ◽  
pp. 23-27
Author(s):  
Edy Soesanto ◽  
Edi Dharmana ◽  
Soeharyo Hadisaputro ◽  
Siti Fatimah Muis

Introduction: Bamboo shoot Gigantochloa apus extract has antioxidant compounds that act as lipid peroxidation inhibitors and reduce free radical formation so that it can be used as an anti-inflammatory and anti-oxidative stress in the atherosclerosis. Aim: Knowing the effect of bamboo shoot Gigantochloa apus extract in reducing MDA levels and IL-10 increasing levels in rabbits given atherogenic diet. Methods: This experiment used randomized pre-test and post-test with control group design, in 24 New Zealand White rabbits divided into 4 groups randomly. MDA and IL-10 levels were examined by the ELISA method. Results and conclusion: Bamboo shoot Gigantochloa apus extract can reduce MDA levels and increase IL-10 levels significantly in accordance with increasing doses. The increase of MDA levels in the control group with all treatment groups was different (p = 0.0001), and between the treatment groups and other treatment groups there were also differences (p


2019 ◽  
Vol 2 (2) ◽  
pp. 269
Author(s):  
Yoga Pratama

The objectives of this study were to find out whether or not there was significant improvement in writing and speaking achievements of the eighth grade students of SMPN1 Jarai after they were taught by using Sociogram, to find out whether or not there was significant improvement in each aspect of writing and speaking achievements of the eighth grade students of SMPN1 Jarai after they were taught by using Sociogram, to find out whether or not there was significant difference in writing and speaking achievements between the eighth grade students of SMP 1 Jarai who were taught by using Sociogram and those who were not, and to find out the perception of the eighth grade students of SMPN 1 Jarai after they were taught by using Socoiogram. In this paper, an experimental research method with pre and post test control group design was used with 70 students as the sample divided into two groups, experimental and control group. However, only the students of the experimental group were taught by using Sociogram. The obtained data were analyzed by using t-test. The students were given questionnaire to know their perceptions. The result showed that there was a significant difference in both students? writing and speaking achievements after they were tought by using Sociogram. Furthermore, it was found that there was a significant difference in students? writing and speaking achievement between the experimental and control groups. In conclusion, Sociogram improves the students? writing and speaking achievements.


2019 ◽  
Vol 39 (4) ◽  
pp. 245-255
Author(s):  
Yanny Octavia Sally Ride ◽  
Yusup Subagio Sutanto ◽  
Debree Septiawan

Background: Anxiolytic premedication can reduce anxiety, improving procedural tolerance, and reduce postbronchoscopic complications. There was ongoing debate about the safety of bronchoscopist-administered sedation. Alprazolam as a surgical premedication can reduce anxiety. Alprazolam can be used as an adjuvant analgesic, to reduce anxiety-related breathlessness, and to reduce coughing as adjuvant antitussive. The study aimed to evaluate the effectiveness of alprazolam in patients undergoing bronchoscopy. Methods: A clinical study with experimental quasi pre-post test control group design, using consecutive sampling was performed in patients with lung tumor undergoing bronchoscopy in dr.Moewardi Hospital from February to March 2019. The study subjects were divided in experimental (alprazolam) and control groups (without alprazolam). The Hospital Anxiety and Depression Scale (HADS), VAS for pain score, modified Borg score, and VAS for cough were measured in baseline, before, and after bronchoscopy. Results: Thirty two lung subjects were included in this study. The intervention groups showed decreased HADS score pre and post bronchoscopy (6.56±2.83 and 6.88±2.63), pain VAS scores (15.00±10.95 and 9.69±11.61), cough VAS score (11.56±8.89 and 27.19±17.89), and these were different significantly compared to control group. We found decreased mean of modified Borg in the study group though they were not significant compared to the control group. Conclusion: Alprazolam controlled anxiety, coughing, and pain in patients undergoing bronchoscopy. Alprazolam minimized breathlessness after bronchoscopy. (J Respir Indo. 2019; 39(4): 245-55)


2017 ◽  
Vol 6 (1) ◽  
Author(s):  
D. K. Sari ◽  
A. Permanasari ◽  
F. M. T. Supriyanti

<p>The purpose of this study is to obtain a profile of students’ creative thinking skills on quantitative project-based protein testing using local materials. Implementation of the research is using quasi-experimental method pre-test post-test control group design with 40 students involved in Biochemistry lab. The research instrument is pre-test and post-test using creative thinking skills in the form of description and students’ questionnaire. The analysis was performed with SPSS 22.0 program to see the significance normality, U Mann-Whitney test for nonparametric statistics, N-Gain score, and the percentage of student responses to the practicum performed. The research result shows that the pretest rate in the experimental group is 8.25 while in the control group is 6.90. After attending a project-based practicum with local materials, the experimental group obtained the mean of posttest is 37.55 while in control class is 11.18. The students’ improvement on creative thinking skills can be seen from the average of N-Gain in the experimental class with 0.32 (medium category) and in the control category with 0.05 (low category). The experimental and control class have different creative thinking skills significantly different fluency, flexibility, novelty, and detail. It can be concluded that quantitative project-based protein testing using local materials can improve students’ creative thinking skills. 71% of total students feel that quantitative project-based protein testing using local materials make them more creative in doing a practicum in the laboratory.</p>


2017 ◽  
Vol 9 (02) ◽  
pp. 49
Author(s):  
Siti Harwanti ◽  
Nur Ulfah ◽  
Budi Aji

Batik maked process especially �mbironi�, is done in sit position. If this position maintained for a long period, that could be cause muscle strain which may lead into musculoskeletal disorders. The research was aim to know the effect of Workplace Stretching Exercise (WSE) to reduced MSDs in hand-made batik workers. The research was quasy experimental by non-equivalent control group design. Subjects were 37 female handmade batik workers used purposive sampling. Data analysis used Friedman test and Wilcoxon test, then for two independent sample used Independent t Test and Mann Whitney test with significancy level at 5% or a = 0,05. Analysis result show that there is no difference in MSDs on experiment and control group after pre-test which had p-value = 0,371 (>0,05). The result of middle-test and post-test p value = 0,000 (<0,05) that there is significant mean difference of MSDs between experiment and control group. Based on the middle-test and post-test analysis result, it could be conclude that there is an effect of WSE to reduce MSDs of handmade batik workers.


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