scholarly journals Kerion Type of Tinea Capitis Treated with Double Pulse Dose Terbinafine

2016 ◽  
Vol 6 (2) ◽  
pp. 34
Author(s):  
Franky Chandra
Keyword(s):  
Tinea Capitis ◽  
Clinical Manifestations ◽  
Double Pulse ◽  
Microsporum Canis ◽  
Fungal Culture ◽  
Pulse Dose ◽  
Mycologic Cure ◽  
Higher Doses ◽  
Dermatophyte Infection

Objective: Tinea capitis is a common dermatophyte infection affecting hair and skin which always requires systemic treatment to get a clinical and mycologic cure, preventing relapse, and infection spread. Griseofulvin has been the antifungal therapy of choice for tinea capitis, but it often requires higher doses and a longer duration than recommended. Thus, effective alternative antifungal with good oral tolerability and shorter course of treatment are therefore required. The objective of this report is to evaluate the effectiveness of double pulse dose terbinafine for tinea capitis alternative therapy.Method: A case of kerion type of tinea capitis in a two-year-old girl was reported. Diagnosis was established based on clinical manifestations of alopecia, presented as erythematous macule with pustules, hemorrhagic crusts, and scales on the scalp, accompanied with occipital lymphadenopathy. Fungal culture showed growth of Microsporum canis (M. canis) colonies. Patient was treated with doubled pulse dose terbinafine 125 mg/day and 2% ketoconazole shampoo for two months.Result: Clinical improvements were found on 35th day of follow up, while mycologic cure was achieved on 60th day of follow up. Tolerability was excellent and no side effects observed.Conclusion: Double pulse dose terbinafine is effective for kerion type of tinea capitis. Key words: double pulse dose, kerion, M. canis, terbinafine, tinea capitis

scholarly journals Comparative study of oral terbinafine vs. oral griseofulvin in the management of tinea capitis

2019 ◽  
Vol 5 (3) ◽  
pp. 629
Author(s):  
Anjani Kumar Shukla ◽  
Bibhuti Bhushan ◽  
Dharmendra Kumar Mishra ◽  
Shyam Sundar Chaudhary ◽  
Mihir Kumar Jha ◽  
...  
Keyword(s):  
Clinical Assessment ◽  
Tinea Capitis ◽  
Fungal Culture ◽  
Treatment Groups ◽  
The Mean ◽  
To Receive ◽  
Tissue Effect ◽  
Dermatophyte Infection ◽  
Oral Terbinafine

<p class="abstract"><strong>Background:</strong> Tinea capitis (TC) is a common dermatophyte infection affecting primarily prepubertal children. The present study has been designed to assess the clinico-etiological profile of the T capitis and to compare the efficacy and tolerability of terbinafine with griseofulvin.</p><p class="abstract"><strong>Methods:</strong> One hundred fifty eight patients of T. capitis were divided into two groups of 79 patients each to receive either oral griseofulvin or terbinafine (according to weight). Patients in both the groups were followed up at 2, 4, 12 and 36 weeks. At every visit, clinical improvement was evaluated using clinical assessment severity score and the compliance, tolerability and side effects of the drugs were assessed along with KOH microscopy, fungal culture from the lesion and relevant blood investigations.<strong></strong></p><p class="abstract"><strong>Results:</strong> The clinical assessment score were statistically similar in group G and group T at the start of therapy. The decline in scores in both treatment groups was statistically significant at each follow up visit. In griseofulvin group, the mean score was declined from 5.9 at baseline to 4.24 at week 2 and 2.79 at week 4, 0.82 at week 12 and 1.24 at 36 week. In the terbinafine group, the score had a mean of 6.23 at 0 week and 4.03 at week 2, 2.32 at week 4, 0.69 at week 12 and 0.83 at week 36.</p><p><strong>Conclusions:</strong> At follow up study long lasting tissue effect of terbinafine was found but effect of griseofulvin was waned at 36 week. So terbinafine may be better option with similar side effect profile but it is better in residual clinical and mycological effect at higher cost.</p>

scholarly journals Tinea Capitis by Microsporum canis in an Elderly Female with Extensive Dermatophyte Infection

2021 ◽  
Vol 186 (2) ◽  
pp. 299-305
Author(s):  
Zhihui Yang ◽  
Wei Chen ◽  
Zhe Wan ◽  
Yinggai Song ◽  
Ruoyu Li
Keyword(s):  
Tinea Capitis ◽  
Disease Onset ◽  
The Body ◽  
Microsporum Canis ◽  
Fungal Culture ◽  
History Of ◽  
Stray Cat ◽  
Immunocompetent Adults ◽  
Effective Drugs ◽  
Dermatophyte Infection

AbstractTinea capitis is a type of dermatophyte infection primarily affecting children. We report a case of an elderly woman with well-controlled diabetes mellitus presenting with a six-month history of erythema with yellow crusts on her scalp and extensive erythematous patches with scales on the body skin. She adopted a stray cat before the disease onset. Dermoscopic findings and manifestation under the Wood’s lamp favoured the diagnosis of tinea capitis. Further microscopic examinations of her scalp, including direct KOH and fluorescence stain examination, fungal culture and polymerase chain reaction sequencing identification confirmed the diagnosis of tinea capitis caused by Microsporum canis. Treatment with oral terbinafine was effective. Adult tinea capitis is often misdiagnosed due to its rarity and atypical presentation. However, in some regions, the incidence of tinea capitis in immunocompetent adults is rising which requires the awareness of clinicians. A thorough history (including the animal contacting history), physical examination and further mycological examinations are required for diagnosis. Trichophyton violaceum is the most common dermatophyte species in most regions while adult tinea capitis caused by Microsporum canis is less common. Terbinafine, griseofulvin and itroconazole have been reported to be effective drugs for the treatment of tinea capitis, and terbinafine can be considered as systemic treatment in elderly patients with comorbidities to reduce the drug–drug interaction.

scholarly journals Isolation of dermatophytes from 50 asymptomatic domestic cats treated at the Federal University of Mato Grosso Veterinary – Hospital in Cuiabá, MT

2016 ◽  
Vol 37 (4) ◽  
pp. 2003 ◽  
Author(s):  
Samara Rosolem Lima ◽  
Wagner Aparecido da Silva ◽  
Marcelo Marques da Silveira ◽  
Rita de Cássia Da Silva Machado Neves ◽  
Valéria Dutra ◽  
...  
Keyword(s):  
Infection Rate ◽  
Skin Diseases ◽  
Clinical Signs ◽  
Microsporum Canis ◽  
Fungal Culture ◽  
Chi Square ◽  
Mato Grosso ◽  
Dermatophytic Fungi ◽  
Veterinary Hospital ◽  
Dermatophyte Infection

Dermatophytosis, commonly known as ringworm, is a zoonotic disease caused by complex fungi that grow as hyphae and attach to the skin, hair and nails or claws. About 40 species of fungi of the genera Microsporum spp., Trichophyton spp. and Epidermophyton spp. are considered dermatophytes, and Microsporum canis is the genus most commonly isolated from cats. This study investigated the occurrence of dermatophytes in cats without clinical signs of skin diseases. The study involved the physical examination of 50 clinically healthy cats and the collection of samples for direct examination and fungal culture at a university veterinary hospital. The resulting data were evaluated by the chi-square association test. Of the 50 cats, 11 (22%) presented dermatophytes, with a predominance of Microsporum spp. The other 39 animals were diagnosed for non-dermatophytic fungi. Sex, breed and the presence of contactants showed no statistical difference, although there was a predominance of adult animals. The high dermatophyte infection rate confirms that cats without clinical signs can harbor these fungi, acting as asymptomatic carriers, contaminating the environment and increasing the infection rate. This study confirms that cats without clinical signs can be carriers of ringworm, which underscores the importance of the adoption of control methods even for clinically healthy animals.

Tinea Capitis: An Updated Review

2020 ◽  
Vol 14 (1) ◽  
pp. 58-68 ◽  
Author(s):  
Alexander K.C. Leung ◽  
Kam L. Hon ◽  
Kin F. Leong ◽  
Benjamin Barankin ◽  
Joseph M. Lam
Keyword(s):  
Antifungal Therapy ◽  
Tinea Capitis ◽  
English Literature ◽  
Combined Therapy ◽  
Hair Follicles ◽  
Microsporum Canis ◽  
Fungal Culture ◽  
Direct Microscopic Examination ◽  
Pubmed Search ◽  
Meta Analyses

Background: Tinea capitis is a common and, at times, difficult to treat, fungal infection of the scalp. Objective: This article aimed to provide an update on the evaluation, diagnosis, and treatment of tinea capitis. Methods: A PubMed search was performed in Clinical Queries using the key term “tinea capitis”. The search strategy included meta-analyses, randomized controlled trials, clinical trials, observational studies, and reviews. The search was restricted to English literature. The information retrieved from the above search was used in the compilation of the present article. : Patents were searched using the key term “tinea capitis” at www.freepatentsonline.com. Results: Tinea capitis is most often caused by Trichophyton tonsurans and Microsporum canis. The peak incidence is between 3 and 7 years of age. Non-inflammatory tinea capitis typically presents as fine scaling with single or multiple scaly patches of circular alopecia (grey patches); diffuse or patchy, fine, white, adherent scaling of the scalp resembling generalized dandruff with subtle hair loss; or single or multiple patches of well-demarcated area (s) of alopecia with fine-scale, studded with broken-off hairs at the scalp surface, resulting in the appearance of “black dots”. Inflammatory variants of tinea capitis include kerion and favus. Dermoscopy is a highly sensitive tool for the diagnosis of tinea capitis. The diagnosis can be confirmed by direct microscopic examination with a potassium hydroxide wetmount preparation and fungal culture. It is desirable to have mycologic confirmation of tinea capitis before beginning a treatment regimen. Oral antifungal therapy (terbinafine, griseofulvin, itraconazole, and fluconazole) is considered the gold standard for tinea capitis. Recent patents related to the management of tinea capitis are also discussed. Conclusion: Tinea capitis requires systemic antifungal treatment. Although topical antifungal therapies have minimal adverse events, topical antifungal agents alone are not recommended for the treatment of tinea capitis because these agents do not penetrate the root of the hair follicles deep within the dermis. Topical antifungal therapy, however, can be used to reduce transmission of spores and can be used as adjuvant therapy to systemic antifungals. Combined therapy with topical and oral antifungals may increase the cure rate.

scholarly journals Prevalence of Tinea Capitis among School Children in Nok Community of Kaduna State, Nigeria

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Josephine Dogo ◽  
Seniyat Larai Afegbua ◽  
Edward Christopher Dung
Keyword(s):  
School Children ◽  
Tinea Capitis ◽  
Cross Sectional Study ◽  
Single Infection ◽  
Microsporum Canis ◽  
Fungal Culture ◽  
Cross Sectional ◽  
Number Of Children ◽  
Mode Of Transmission ◽  
Group 5

In recent years, the prevalence of tinea capitis, an infection of the scalp by dermatophytes, has increased in children worldwide. This cross-sectional study was carried out to determine the prevalence and risk factor of tinea capitis among school children in Nok community of Kaduna State, Nigeria. A total of 100 children were screened and 45% were diagnosed to have tinea capitis after fungal culture and microscopy. The prevalence of tinea capitis among girls was higher (51.4%) than that among boys (41.5%) but not significantly different (p=0.402). The prevalence with respect to age was lower for the age group 5–10 years (42.6%) than that of 11–15 years (50%) but was not significantly different (p=0.524).Trichophyton rubrum(28.8%) andMicrosporum canis(22.7%) were the most prevalent dermatophytes isolated and the least wereTrichophyton verrucosum(4.5%) andTrichophyton tonsurans(4.5%). There were 73.3% single infection while 26.7% had 2–4 dermatophytes of the generaMicrosporumandTrichophyton. The predisposing factors with statistically significant association with tinea capitis were number of children in the family (p=0.02) and sharing of the same bed (p=0.002). This indicates the high tendencies of spread of tinea capitis through human-to-human mode of transmission and possible animal contact. Community health education on the cause, mode of transmission, prevention, and prompt treatment of tinea capitis is recommended.

scholarly journals Urticaria Pigmentosa Due to Microsporum canis Infection in a Sphynx Cat – Case Report

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Szczepanik Marcin ◽  
Wilkołek Piotr ◽  
Kalisz Grzegorz ◽  
Śmiech Anna
Keyword(s):  
Case Report ◽  
Mast Cells ◽  
Skin Biopsy ◽  
Urticaria Pigmentosa ◽  
Microsporum Canis ◽  
Fungal Culture ◽  
Well Differentiated ◽  
Dermatophyte Infection

AbstractA two- year-old Sphynx cat, an unneutered female with multiple erythematous papules with hyperpigmentation was presented. In skin biopsy, in the dermis, well differentiated monomorphic mast cells were found. Fungal culture was positive for Microsporum canis. Diagnosis of urticaria pigmentosa following M. canis infection was made. The animal was successfully treated with itraconazole orally and shampoo containing chlorhexidine and miconazole. To the authors’ knowledge, this is the first reported case of urticaria pigmentosa following the dermatophyte infection in a Sphynx cat.

scholarly journals Tinea capitis: study of asymptomatic carriers and sick adolescents, adults and elderly who live with children with the disease

2001 ◽  
Vol 43 (2) ◽  
pp. 87-91 ◽  
Author(s):  
Christiane Loureiro BERGSON ◽  
Nurimar Conceição FERNANDES
Keyword(s):  
Disease Control ◽  
Rio De Janeiro ◽  
Tinea Capitis ◽  
Female Adolescent ◽  
Microsporum Canis ◽  
Trichophyton Tonsurans ◽  
Asymptomatic Carriers ◽  
Adolescents And Adults ◽  
Dermatophyte Infection

Tinea capitis is a dermatophyte infection that occurs mainly in childhood; there are few reports, in Brazil, in adolescents and adults. The detection of asymptomatic carriers is of great importance in the disease control. From February 1998 to February 1999, a study was performed at the outpatient Dermatologic Unit of Instituto de Puericultura e Pediatria Martagão Gesteira (Universidade Federal do Rio de Janeiro, Brasil) to verify the frequency of asymptomatic carriers and tinea capitis between 79 adolescents, adults and elderly who lived in the same household of 56 children (0-12 years) with tinea capitis. Of these, one female and one male adults (2.5%) were asymptomatic carriers and the cultures revealed Trichophyton tonsurans and Microsporum canis respectively. One female adolescent and two female adults (3.8%) had tinea capitis and all cultures revealed Trichophyton tonsurans. The study has shown that adolescents and adults who live in the same household of children with tinea capitis may be sick or asymptomatic carriers.

scholarly journals Subcutaneous phaeohyphomycosis: A rare case

2019 ◽  
Author(s):  
Zahruddin Ahmad ◽  
Diah Mira Indramaya ◽  
Yuri Widia ◽  
Sylvia Anggraeni ◽  
Linda Astari ◽  
...  
Keyword(s):  
Subcutaneous Tissue ◽  
Clinical Manifestations ◽  
Granulomatous Inflammation ◽  
Surgical Excision ◽  
Fungal Culture ◽  
Human Beings ◽  
Nodular Lesions ◽  
Subcutaneous Phaeohyphomycosis ◽  
Tuberculosis Therapy

Phaeohyphomycosis is a rare fungal infection caused by melanized fungi which usually involve the skin and subcutaneous tissue. It is an infrequent cause of infection in human beings. Common clinical manifestations are subcutaneous cystic swellings, which is localized, characterized by subcutaneous asymptomatic nodular lesions that develop after traumatic implantation of fungus from contaminated soil, thorns or wood splinters, especially on extremities. We report a case of subcutaneous phaeohyphomycosis presenting as multiple cystic swellings over the left lower leg with unknown predisposing factors. At first, the patient was misdiagnosed as soft tissue tumor and subcutaneous tuberculosis, then got surgical and anti-tuberculosis therapy respectively, but there was no improvement. Further investigation revealed granulomatous inflammation on histopathology examination and black-coloured colonies identifed as Exophiala dermatitidis on fungal culture. This case of phaeohyphomycosis was successfully treated by itraconazole monotherapy without surgical excision and still under follow-up.

scholarly journals A Case of Tinea Pseudoimbricata by Trichophyton tonsurans

2021 ◽  
pp. 13-16
Author(s):  
Jeongsoo Lee ◽  
Yongwoo Choi ◽  
Joonsoo Park
Keyword(s):  
Tinea Capitis ◽  
Clinical Manifestations ◽  
Tinea Corporis ◽  
Fungal Culture ◽  
Trichophyton Tonsurans ◽  
The Common ◽  
Microscopic Findings ◽  
Oral Terbinafine

Tinea imbricata is a unique dermatophytosis caused by Trichophyton concentricum, observed endemically in subtropical to torrid zones. It is characterized by development of impressive concentric rings on the trunk or limbs. And few dermatophytosis cases mimicking this disease are reported as "tinea pseudoimbricata". Herein, we report a case of tinea pseudoimbricata caused by T. tonsurans with multiple concentric annular erythemas. The common clinical manifestations of T. tonsurans infection are tinea capitis and tinea corporis. However, tinea imbricate-like lesions are very rare. Fungal culture and microscopic findings confirmed a T. tonsurans infection in this case. The patient was treated with topical isoconazle and additional oral terbinafine.

scholarly journals Profile of patients with tinea capitis

2019 ◽  
Author(s):  
Siti Amira Venitarani ◽  
Samsriyaningsih Handayani ◽  
Evy Ervianti
Keyword(s):  
Retrospective Study ◽  
Positive Result ◽  
Tinea Capitis ◽  
Microsporum Canis ◽  
Age Group ◽  
Predisposing Factor ◽  
Patch Type ◽  
Prepubertal Children ◽  
Main Complaint ◽  
Dermatophyte Infection

Tinea capitis is dermatophyte infection of the scalp and hair, affecting mainly prepubertal children. Its incidence has increased over the last decades. If not diagnosed and treated properly, it might reach epidemic soon. This study was descriptive retrospective study which evaluated the incidence and profile of tinea capitis among patients of Micology Division, Outpatient Clinic of Dermatology and Venereology Department, Dr. Soetomo General Hospital Surabaya in 2014 - 2016. There were 42 tinea capitis new cases. It was most prevalent among the age group of 5-14 years old. Male was more common. The most common main complaint was itching. The most frequent predisposing factor was cat exposure. Squama was the most prevalent efflorescence. KOH examination data showed that 57.1% patients were arthrospore positive and 66.7% were positive in Wood lamp examination. Culture was done among 24 patients with positive result of 52.4% and Microsporum canis as the most prevalent dermatophytes. There were 33.3% patients diagnosed with grey patch type. The most common treatment was oral griseofulvin. Follow-ups were done to all patients but only 64.3% who visited back.

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