scholarly journals Modern clinical manifestations of tick-borne encephalitis in Tomsk region

2006 ◽  
Vol 5 ◽  
pp. 52-56
Author(s):  
N. G. Zhoukova ◽  
A. V. Lepyokhin ◽  
L. V. Loukashova ◽  
R. F. Nasyrova ◽  
N. V. Ryazantseva ◽  
...  
Keyword(s):  
Russian Federation ◽  
Clinical Manifestations ◽  
Morbidity Rate ◽  
Natural Focus ◽  
Tick Borne Encephalitis ◽  
Tomsk Region ◽  
The Russian Federation ◽  
Active Natural

The article presents the results of clinical and epidemiological investigations of morbidity rate of tick-borne encephalitis (TBE) in Tomsk region in a period of 1944—2005. it is shown that Tomsk region is an active natural focus of TBE, leading among other regions of the Russian Federation in morbidity rate and spreading of the infection. Main features of pathomorphosis of clinical ma- nifestitions of TBE were analysed: prevailing of fever and latent forms was determined, as well as decrese of paralytic and menin- geal forms levels.

scholarly journals PROBLEMS IN THE ORGANIZATION OF EPIDEMIC SURVEILLANCE OF LEPTOSPIROSIS IN A SUBJECT OF THE RUSSIAN FEDERATION

2012 ◽  
Vol 17 (1) ◽  
pp. 46-48
Author(s):  
A. A. Nafeyev
Keyword(s):  
Infectious Diseases ◽  
Russian Federation ◽  
Climatic Factors ◽  
Laboratory Diagnosis ◽  
Natural Focus ◽  
Epidemic Process ◽  
Natural Foci ◽  
The Russian Federation ◽  
Active Natural

This paper characterizes the epidemic process of leptospirosis. The current new herd infections are typified by: 1) the formation of new natural foci under anthropogenic and climatic factors; 2) the change in the biocenotic structure of natural foci; 3) the formation of natural foci of mixed infectious diseases of bacterial and virus etiology; 4) the change in the epidemic potential of natural foci; 5) synathropization of infectious diseases. Few or no registered leptospirosis cases in some silent areas are frequently attributable to poor differential, including laboratory, diagnosis. The epidemic process is characterized in terms of the active natural focus of leptospirosis in a long-term period.

scholarly journals Trends in Epidemic Process Development of Tick-Borne Encephalitis in the Russian Federation, Laboratory Diagnosis, Prophylaxis and Forecast for 2021

2021 ◽  
pp. 6-16
Author(s):  
E. I. Andaev ◽  
A. Ya. Nikitin ◽  
E. V. Yatsmenko ◽  
E. V. Verigina ◽  
M. I. Tolmacheva ◽  
...  
Keyword(s):  
Russian Federation ◽  
Temperate Climate ◽  
Public Health Issue ◽  
Morbidity Rate ◽  
Management Decision ◽  
Forest Steppe ◽  
Human Welfare ◽  
Tick Borne Encephalitis ◽  
Natural Foci ◽  
The Russian Federation

Tick-borne encephalitis is a natural-focal infection damaging central nervous system, caused by the similarly-named virus transmitted by several species of ixodic ticks. Natural foci of tick-borne encephalitis (TBE) are widely spread in the forest and forest-steppe landscape zones of the temperate climate belt in the vast territory of Eurasia from the Atlantic to the Pacific Ocean. New TBE-endemic territories have been recently identified in Japan, the Netherlands, and in the UK – in 2019. The increasing risk of infection due to the development of tourism and visits to natural foci of TBE became a public health issue of international concern. The aim of the study is to identify modern features of TBE incidence dynamics in the Russian Federation, the state of laboratory diagnostics and prevention and to predict the incidence for 2021. The paper shows that there is a persistent downward trend in TBE-cases in Russia, which is observed through the past few years. The characteristic feature of the epidemic season-2020 was a significant reduction in the incidence of TBE: 989 cases were registered in 33 constituent entities of the Russian Federation (morbidity rate – 0.67 per 100 000 of the population). The sharp decrease of TBE cases in 2020 as compared to 2019 against the background of a decrease in vaccination can be explained, along with natural factors, by the introduction of restrictive measures during the COVID-19 epidemic. The paper also reflects the dynamics of morbidity, seeking the medical services because of tick bites, the infection rate of the carrier, the scope of vaccination, seroprophylaxis, acaricide treatments. The coverage of express-diagnostic tests of ticks for markers of associated pathogens and its availability for the population are presented. It is recognized that the epidemiological situation on TBE in the Russian Federation remains unfavorable. It demands constant attention on the part of healthcare organizations and Federal Service for Surveillance in the Sphere of Consumers Rights Protection and Human Welfare, as well as management decision making aimed at further decrement in TBE incidence through the improvement of prevention measures, specifically in the entities that are characterized by high TBE incidence. The situation requires monitoring of natural foci of infection, enhancement of prophylaxis and treatment of TBE. The paper provides the forecast of TBE incidence for 2021 and values of the 95 % confidence range of the indicator fluctuation, taking into account the presence or absence of trends in its changes in the territory of federal districts and constituent entities of the Russian Federation in 2011–2020.

Molecular Epidemiological Monitoring of Circulation of Coxsackievirus A10

2021 ◽  
pp. 43-49
Author(s):  
LN Golitsyna ◽  
VV Zverev ◽  
NV Ponomareva ◽  
NI Romanenkova ◽  
Thao Thanh Thi Nguyen ◽  
...  
Keyword(s):  
Russian Federation ◽  
Molecular Genetic ◽  
Clinical Manifestations ◽  
Foot And Mouth Disease ◽  
Sewage Water ◽  
Epidemiological Surveillance ◽  
Molecular Monitoring ◽  
South Vietnam ◽  
Epidemiological Monitoring ◽  
The Russian Federation

Background: Coxsackievirus A10 (CV-A10) is currently one of the most common etiological agents of enterovirus infection (EVI). Over the past decade, severe and fatal cases of CV-A10 infection have become more frequent while clinical manifestations of the disease are similar to those of Enterovirus A71 infection. The objective of our study was to characterize circulation of Coxsackievirus A10 in the Russian Federation in 2008–2019 and to study the phylogenetic relationships of strains isolated in Russia and Vietnam. Materials and methods: In 2008–2019, 220 CV-A10 strains were isolated from patients with various clinical manifestations of EVI and from sewage water samples taken in the Russian Federation and then studied using molecular genetic methods. In addition to that, we analyzed 26 CV-A10 strains isolated from patients with hand, foot, and mouth disease (HFMD) and acute flaccid paralysis in South Vietnam in 2018–2019. Results: We established a two-year periodicity of CV-A10 active circulation in Russia. In the structure of clinical forms of CV-A10 infection, herpetic angina prevailed (30.8 %), followed by minor illness (25.25 %), respiratory diseases (15.66 %), exanthema (14.65 %), gastrointestinal disorders (8.08 %), and asymptomatic infections (2.02 %). Symptoms of CNS damage (meningitis, meningoencephalitis) were observed in 3.53 % of cases. Most CV-A10 strains from Vietnam were isolated from patients with CNS affection of varying degrees of severity. During the study period, CV-A10 strains of genotypes C, E, and F3 circulated in the territory of the Russian Federation whereas the strains from South Vietnam were represented by genotypes F3 and F1. The studied strains showed a genetic relationship with those of CV-A10 circulating in different countries. Vietnamese and some Russian strains of the F3 genotype were genetically close to the strains isolated from severe cases. Conclusions: Molecular monitoring of CV-A10 circulation is an important component of the global epidemiological surveillance of EVI.

scholarly journals BIOGRAPHY OF SURGEON B. I. FUKS IN THE CONTEXT OF THE SOVIET ERA HISTORY

2018 ◽  
pp. 36-45 ◽  
Author(s):  
E. S. Genina ◽  
B. B. Fuks
Keyword(s):  
Russian Federation ◽  
The State ◽  
Advanced Training ◽  
State University ◽  
Medical Sciences ◽  
State Institute ◽  
Tomsk Region ◽  
History Of ◽  
The Russian Federation ◽  
State Archives

The authors of this article aimed at reconstructing the biography of B. I. Fuks in the context of the history of the Soviet era and its most important events. Boris Ilyich (Ber Eljich) Fuks (1897–1973) was a Doctor of Medical Sciences, Professor, a surgeon, the founder of Novokuznetsk Surgical School. His scientific and pedagogical activity was primarily connected with the Tomsk State University and the State Institute for Advanced Training of Doctors, consistently located in Tomsk, Novosibirsk, Stalinsk (Novokuznetsk). The research is based on the documents found in the State Archives of the Russian Federation, the State Archives of Tomsk Region, the State Archives of Kemerovo Region, the State Archives of Kemerovo Region in Novokuznetsk, and the Archives of Novokuznetsk State Institute for Advanced Training of Doctors, and some publications in the central and local periodicals. The documents from the personal archive and memoirs of B. B. Fuks, the son of B. I. Fuks (Boston, USA), made up a separate important set of sources.

Fibromyalgia: clinical presentation and variants of the disease

2020 ◽  
Vol 14 (2) ◽  
pp. 45-51
Author(s):  
O. V. Teplyakova ◽  
A. A. Popov ◽  
L. I. Volkova ◽  
A. V. Sarapulova
Keyword(s):  
Cognitive Impairment ◽  
Russian Federation ◽  
Clinical Manifestations ◽  
Depression Scale ◽  
Somatic Symptoms ◽  
Pain Syndrome ◽  
Female Gender ◽  
Additional Risk Factor ◽  
The Russian Federation ◽  
Industrial Center

Fibromyalgia (FM) is a condition characterized by generalized pain syndrome and by the presence of fatigue, cognitive impairment, affective and multiple somatic symptoms. Pain syndrome can have national, ethnic, gender, and age characteristics.Objective: to evaluate the features of the course of FM in a large industrial center of the Russian Federation and to present its phenotypic options.Patients and methods. The investigation enrolled 92 FM patients (8 men, 84 women) aged 18 to 86 years (mean age, 50.5 years). The diagnosis was established according to the 2016 ACR criteria. Account was taken of data on disease duration, occupation, sport training loads, previous therapy, pain intensity, and somatic symptoms according to the 2010 ACR diagnostic criteria and on general health assessment in the patients. All the patients completed the hospital anxiety and depression scale (HADS).Results and discussion. The most significant somatic symptoms in the clinical picture of FM were shown to be muscle pain and muscle weakness, the manifestations of irritable bowel syndrome and fatigue; moreover, the prevalence of many symptoms in people over 60 years of age was lower than that in younger patients. Female gender was an additional risk factor for increases in pain and cognitive impairment. The presence of concomitant depression verified by HADS was associated with a substantial deterioration of the clinical manifestations of FM. At the same time, professional activities and sports were found to be protective factors against a number of symptoms of FM. It was hypothesized that there were several FM phenotypes (anxious, anxiety-depressive, egocentric, and vascular ones).Conclusion. The authors have demonstrated the features of the course of FM in a large industrial center of the Russian Federation and identified various disease phenotypes, which can be useful for determining the treatment policy for patients.

Attitudes Towards The Governmental Authorities And Specific Features Of Self-Identification Of Business Support Programme Participants

2012 ◽  
Vol 5 ◽  
Author(s):  
Svetlana Litvina
Keyword(s):  
Empirical Research ◽  
Russian Federation ◽  
Demographic Characteristics ◽  
Psychological Profiles ◽  
Support Programme ◽  
Business Support ◽  
Tomsk Region ◽  
The Russian Federation ◽  
Paternalistic Attitude

The article presents the results of empirical research on the Russian  mentality. A regional  sampling  (inhabitants  of Tomsk region of the Russian Federation) provided the basisfor  investigating  the  attitude  towards  paternalism as concerning the governmental authorities and describing the psychological  profiles  of  its  two  empirical  types,  such  as"agreement paternalism" and "obedience paternalism". The interconnections  of  the  paternalistic  attitude, the Russian self­identity  structure,  and  certain  social­ demographic characteristics  have  been  analysed. The article describes specific  features  of  the paternalistic attitude and the self­identity  structure  of  the participants of a business support programme in the Russian Federation.

scholarly journals FMD EPIDEMIC PROCESS CHARACTERISTICS IN RUSSIA IN 2010 – FIRST QUARTER OF 2019

2019 ◽  
pp. 39-44
Author(s):  
V. P. Semakina ◽  
T. P. Akimova ◽  
A. K. Karaulov
Keyword(s):  
Russian Federation ◽  
Animal Health ◽  
Foot And Mouth Disease ◽  
Viral Disease ◽  
Morbidity Rate ◽  
Primorsky Krai ◽  
African Countries ◽  
Epidemic Process ◽  
The World ◽  
The Russian Federation

Foot-and-mouth disease is a highly contagious viral disease of cloven-hoofed livestock and wild animals. Europe, North America and Oceania have long been FMD free; at the same time, the virus is widely spread in Asian and African countries. In the period from 2010 to March 2019, FMD was notified to the World Organisation for Animal Health (OIE) by 89 countries of the world. Local FMD outbreaks were also reported in several regions of the Russian Federation throughout this period. The research was aimed at studying some characteristics of the FMD epidemic process in the Russian Federation. The undertaken epidemiological analysis covers the Russian Federation regions where FMD outbreaks were reported between 2010 and March 2019. During the period under consideration, FMD cases were reported in 9 regions of the Russian Federation, mainly in the settlements located in close proximity to the Russia-China and Russia-Mongolia international borders. Most of the outbreaks were caused by serotype O and A FMD viruses. In most cases, FMD was reported in cattle and pigs and, less frequently, in sheep and goats. The analysis of the FMD epidemic situation in the Russian Federation Subjects was performed through epidemic process assessment based on the following estimates: the proportion of infected settlements, epidemic, contagiousness and morbidity rates. The Zabaykalsky and Primorsky Krais have a lead in the number of infected settlements. The highest morbidity rate in pigs was recorded in the Primorsky Krai, in cattle – in the Amur Oblast. The epidemic rate was the highest in the Primorsky and Zabaykalsky Krais. The Primorsky Krai also accounted for the highest contagiousness rates in 2014 and 2019 when FMD occurred on several large pig farms.

scholarly journals Russian Experience of Transport Extracorporeal Membrane Oxygenation

2021 ◽  
Vol 9 (4) ◽  
pp. 521-528
Author(s):  
D. A. Shelukhin ◽  
A. V. Karpov ◽  
M. V. Ketskalo ◽  
K. K. Gubarev
Keyword(s):  
Extracorporeal Membrane Oxygenation ◽  
Clinical Experience ◽  
Russian Federation ◽  
Age Groups ◽  
Clinical Manifestations ◽  
Practical Experience ◽  
Hospital Survival ◽  
Membrane Oxygenation ◽  
Significant Difference ◽  
The Russian Federation

Relevance. The present time can be called a period of accumulation of experience of national health systems in different countries of the world in the application of transport extracorporeal membrane oxygenation (ECMO) technology at the pre- and inter-hospital stages of evacuation of patients to specialized ECMO-therapy centers. The role of such centers is to provide timely advice and, if necessary, perform inter-hospital evacuation.Material and methods. The study summarized and analyzed with the help of the national register “RosECMO” the own experience of 13 hospitals in the Russian Federation, who performed 68 inter-hospital evacuations under ECMO conditions by different modes of transport in patients of different age groups with symptoms of circulatory and respiratory failure. The following parameters were evaluated: characteristics of transport ECMO, clinical manifestations of potentially negative effects of transport, hospital survival, as well as the effect of experience (less and more than 10 cases of transport ECMO) of the presented clinics on the difference in the results obtained.Results. Connecting patients to the ECMO device reduces the likelihood of death on the SOFA and APACHE IV scales by 1.2 times (p <0.0001) and 1.4 times (p<0.0001), respectively. Despite the absence of deaths during inter-hospital transportation of patients under ECMO conditions, 14.93% of patients died within 3 days from the moment of their execution, without a significant difference in clinics with different practical experience. The overall hospital survival rate of ECMO transport scenarios in all 13 clinics of the Russian Federation was comparable to the data of the international register 48.52% versus 48.81%, at the same time it was significantly lower (1.3 times) in the group of clinics with less clinical experience 40% versus 52.08% (p<0.0001).Conclusion. The results of the first stage of the study we obtained indicate the prospects of using the method of extracorporeal membrane oxygenation at the stage of inter-hospital evacuation, due to the effective stabilization of the patient’s condition and a significant reduction in the risks of the likelihood of death. Clinics with less clinical experience showed significantly worse results of hospital survival of patients who underwent inter-hospital transportation under conditions of extracorporeal membrane oxygenation compared to clinics with more clinical experience, which can be a significant argument in adopting a model for the development of specialized regional centers for extracorporeal membrane oxygenation. The experience accumulated over the past six years and the analysis of new data from the register of transport cases of extracorporeal membrane oxygenation of the national healthcare system will make it possible to formulate the correct trajectory for the development of the method of extracorporeal membrane oxygenation and its application, including at the stage of pre- and inter-hospital evacuations of patients.

scholarly journals Epidemiological Features of Combined Natural-Focal Infections

2017 ◽  
Vol 16 (5) ◽  
pp. 43-52 ◽  
Author(s):  
V. V. Shkarin ◽  
A. S. Blagonravova ◽  
E. M. Chumakov
Keyword(s):  
Russian Federation ◽  
Mixed Infection ◽  
Quantitative Estimation ◽  
Clinical Manifestations ◽  
Original Research ◽  
Epidemiological Features ◽  
Natural Foci ◽  
The Russian Federation ◽  
And Control ◽  
Reservoir Hosts

On the basis of literature data and results of own research in the article describes the features of the epidemiology of combined natural focal infections, their distribution in the Russian Federation, pathogenesis and clinical features to suit different combinations of pathogen agents. The data on the mixed infection of ticks by different agents in various combinations, as well as polyetiology infected of reservoir hosts Showing different variants of combined natural focal infections in humans caused by the associations of microorganisms, including up to five assiociants, as well as features of the pathogenesis and clinical manifestations Based on original research developed a method of a quantitative estimation the activity of combined natural foci and complex of measures on surveillance and control of combined natural focal infections.

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