scholarly journals Kejadian Ekstravasasi Obat Kemoterapi pada Pasien Kanker

2018 ◽  
Vol 11 (3) ◽  
pp. 142
Author(s):  
Marisa Junianti Manik

Chemotherapy is a cancer management with drugs. The complication that can be occurred is extravasation. The objective of this study was to analyze factors such as vein conditions, type of medications/chemotherapeutic agents, volume of chemotherapeutic agents, and their correlation with chemotherapy drugs extravasation incidences. This study used cross-sectional observational analytic design, with purposive sampling. The sample of this study was 70 cancer patients undergoing chemotherapy in hospitals. Inclusive criteria were patients with ages 18-65 in their first to fifth cycle of chemotherapy. The observation form was used as research instrument. The study showed that there were no correlation between vein conditions, type of medications/chemotherapeutic agents, and volume of chemotherapeutic agents with extravasation. Most veins were still in good condition while undergoing chemotherapy. The length of time for administering chemotherapy were mostly <24 hours, which contributed for reducing risk for extravasation, although the type of medication used were irritants and vesicants, and with drugs volume of 100�1000 milliliter. The incidences of extravasation that were immediately can be observed during chemotherapy occurred 7.14% of the time. It was possibly occurred by medical devices used, such as infusion pump that was facilitated the nurses in early anticipate drugs leakage outside the veins tissue. Nurses� roles also contributed to reduced extravasation risks. As conclusion, the results shown there were no correlation statistically; however there might be other contributing factors that need to be explored furthermore.

2019 ◽  
Vol 14 (2) ◽  
pp. 170
Author(s):  
Silviana Putri ◽  
Merryana Adriani ◽  
Yayuk Estuningsih

Chemotherapy drugs used to kill or inhibit proliferation of cancer cell that are cytotoxic and causing side effect for breast cancer patients. The side effect of chemotherapy drugs is decreasing the appetite which causing decrease in energy and protein intake, and could affect nutritional status. This study aim to determine the relationship between appetite with energy and protein intake of post chemotherapy breast cancer patients. This research was an analytic observational research using cross sectional design and purposive sampling conducted at Dr. Ramelan Navy Hospital Surabaya with a sample size of 50 patients. Correlation between appetite with energy and protein intake were analyzed using Pearson correlation. The average of energy and protein intake were 976.3±304.2 kcal and 29.4±12.9 g. Pearson correlation test showed signifi cant correlation between appetite as chemoteraphy side effect with energy intake (p=0.000; r=-0.558) and protein intake (p=0.000; r=-0.504). Decreasing of appetite due to chemoterapy reduce the energy and protein intake of breast cancer patient. Patient are suggest to consume foods in small portion but often to maintain adequate energy and protein intake.


2021 ◽  
pp. 107815522110562
Author(s):  
Moataz M Hassan ◽  
Dhabya Al-Marzooq ◽  
Hanan Al-Habsi ◽  
Amna Al-Hashar ◽  
Murtadha Al-Khabori ◽  
...  

Background Safe handling of oral anticancer agents is of great concern. There is a lack of clear, national guidelines on how patients can safely handle and dispose of unwanted medications. We aimed to evaluate the safe handling, storage, and disposal of oral anticancer drugs among cancer patients and caregivers at home. Method This cross-sectional survey of adult cancer patients (or their adult caregivers) used a closed-ended questionnaire from May 2019 to March 2020. Results A total of 257 patients (50 ± 15 years; range: 18–93 years) were enrolled; however, only 91% (233/257) reported self-administering oral anticancer medications. Caregivers were more likely to administer oral anticancer agents for patients ≥60 years than those <40 years old (63% vs. 8%; P = 0.001). Most patients (52%; 133/257) did not wash their hands after administering the drug; 74% (164/222) of the respondents reported that their medications were kept in a bedroom cabinet, while 18% (40/222) stored their medications in a refrigerator, and 5% (12/222) in a kitchen cabinet. A total of 55% (68/124) of patients returned their excess oral chemotherapy medications to the hospitals; however, 36% (45/124) disposed of their unused oral chemotherapy drugs in a household garbage container. Conclusion While two-thirds of patients stored their oral anticancer medications properly, more than half used inappropriate handling procedures. Disposal practices were inconsistent and did not adhere to the reported international guidelines.


Author(s):  
Denny Yu ◽  
Kang-Yu Hsu ◽  
Joon Hong Kim ◽  
Poching DeLaurentis

Infusion pumps are medical devices that deliver medication, fluids, and nutrients in a precise and controlled manner that is critical to patient care. This study proposes using infusion pump informatics on all-infusion datasets to understand current impact of alerts and alarms on patient care and health practitioner workflow. All-infusion datasets contain infusion data for both normal and abnormal use, i.e., error states. Ten months of continuous data was collected from one health institution. Analysis of variance with log-transformation and logistic regressions were used to analysis contributing factors for alerts and alarms states. A total 64,511 minutes of alarm activation were observed, where alarms were active prior to being resolved. Mean resolution times for 83% of alarms were one minute or less; however, 3% or alarms required >4 minutes before getting resolved. Risk factors for infusions with alerts included nursing shift variables. Specifically, odds for alerts were 1.3 times higher for infusions that span across shifts than infusions in the day shift.


2019 ◽  
Vol 8 (2) ◽  
pp. 129
Author(s):  
Yori Yuliandra ◽  
Hansen Nasif ◽  
Sabrina Ermayanti ◽  
Lilik Sulistyowati ◽  
Dian A. Juwita

The use of chemotherapeutic agents in the management of cancer is often followed by a range of toxicities to various organ systems. A retrospective study on the hematologic toxicities of chemotherapy in lung cancer patients has been carried out. The study was conducted by a cross-sectional method from medical records of four-year data in 2010–2014 at Dr. M. Djamil Hospital Padang, West Sumatra, Indonesia. Data from medical records of patients diagnosed with lung cancer and underwent chemotherapy, not suffering from primary hematologic diseases, and with normal kidney and liver function prior to chemotherapy were studied. A number of 22 medical records of lung cancer patients which met the criteria with a total of 40 chemotherapy cycles were observed. The study revealed that a combination of carboplatin-paclitaxel was the most common chemotherapy used for the patients (72.7%). The hematologic toxicities comprised anemia, leukopenia, and thrombocytopenia with the severity ranging from grade 1–3. Carboplatin-paclitaxel was the only combination that caused these three toxicities, and the only combination to cause thrombocytopenia as well. Anemia was the major hematologic toxicity experienced by more than half of the patients. The study concludes that there is a reasonably high incidence of hematologic toxicities from chemotherapy among lung cancer patients.Keywords: Anemia, chemotherapy, hematologic toxicity, leukopenia, lung cancer, thrombocytopenia Toksisitas Hematologis Akibat Kemoterapi pada Pasien Kanker Paru: Studi Retrospektif di RSUP Dr. M. Djamil PadangAbstrak Penggunaan obat kemoterapi dalam pengobatan kanker sering disertai dengan toksisitas pada beberapa sistem organ. Kajian retrospektif terhadap toksisitas hematologis akibat kemoterapi pada pasien kanker paru sudah dilaksanakan. Studi ini dilaksanakan dengan metode cross-sectional dari data rekam tahun 2010–2014 di RSUP Dr. M. Djamil Padang, Sumatera Barat. Data pasien yang didiagnosis menderita kanker paru yang menjalani kemoterapi, tidak menderita penyakit hematologis dan gangguan hematopoiesis, serta memiliki fungsi ginjal dan hati yang normal dimasukkan ke dalam kajian. Sejumlah 22 pasien memenuhi kriteria dengan jumlah siklus kemoterapi sebanyak 40. Hasil kajian ini mengungkap bahwa kombinasi karboplatin-paklitaksel merupakan kemoterapi yang paling banyak digunakan (72,2%). Toksisitas hematologis yang terjadi meliputi anemia, leukopenia, dan trombositopenia dengan tingkat keparahan 1–3. Karboplatin-paklitaksel merupakan satu-satunya kombinasi kemoterapi yang menyebabkan ketiga toksisitas hematologis tersebut, sekaligus juga merupakan satu-satunya kombinasi yang menimbulkan trombositopenia. Anemia merupakan toksisitas hematologis yang paling banyak terjadi meliputi lebih dari separuh pasien. Penelitian ini menyimpulkan bahwa terdapat toksisitas hematologis yang cukup tinggi akibat kemoterapi pada pasien kanker paru.Kata kunci: Anemia, kanker paru, kemoterapi, leukopenia, toksisitas hematologis, trombositopenia


2016 ◽  
Vol 34 (26_suppl) ◽  
pp. 231-231
Author(s):  
Harminder Singh ◽  
Raja Banipal

231 Background: The State of Punjab is experiencing a rising burden of cancer. The objective of this study was to analyze and compare depression, anxiety and stress levels and their impacting factors in heterogenous surviving cancer patients. Methods: this is a cross sectional study, data collection was performed by Depression, anxiety, stress scale 21-DASS 21. Results: study population include 300 cancer patients and 300 matched controls. The mean age of the cases and controls were 50.58 years ± 13. 64 and 46.1 years ± 11.78 (M ± SD). A Statistical significant difference was observed in mean scoring of depression, anxiety and stress in cancer patients when compared to control groups. Anxiety mean score significantly affected by chemotherapy cycles and duration of disease. Conclusions: Holistic approach in cancer management is a need of time as the present study revealed, the range of depression, anxiety and stress was 90%, 56% and 28% respectively. [Table: see text]


2021 ◽  
Vol 28 (4) ◽  
pp. 3124-3138
Author(s):  
Mar Sempere-Bigorra ◽  
Iván Julián-Rochina ◽  
Omar Cauli

Although cancer and diabetes are common diseases, the relationship between diabetes, neuropathy and the risk of developing peripheral sensory neuropathy while or after receiving chemotherapy is uncertain. In this review, we highlight the effects of chemotherapy on the onset or progression of neuropathy in diabetic patients. We searched the literature in Medline and Scopus, covering all entries until 31 January 2021. The inclusion and exclusion criteria were: (1) original article (2) full text published in English or Spanish; (3) neuropathy was specifically assessed (4) the authors separately analyzed the outcomes in diabetic patients. A total of 259 papers were retrieved. Finally, eight articles fulfilled the criteria, and four more articles were retrieved from the references of the selected articles. The analysis of the studies covered the information about neuropathy recorded in 768 cancer patients with diabetes and 5247 control cases (non-diabetic patients). The drugs investigated are chemotherapy drugs with high potential to induce neuropathy, such as platinum derivatives and taxanes, which are currently the mainstay of treatment of various cancers. The predisposing effect of co-morbid diabetes on chemotherapy-induced peripheral neuropathy depends on the type of symptoms and drug used, but manifest at any drug regimen dosage, although greater neuropathic signs are also observed at higher dosages in diabetic patients. The deleterious effects of chemotherapy on diabetic patients seem to last longer, since peripheral neuropathy persisted in a higher proportion of diabetic patients than non-diabetic patients for up to two years after treatment. Future studies investigating the risk of developing peripheral neuropathy in cancer patients with comorbid diabetes need to consider the duration of diabetes, cancer-induced neuropathic effects per se (prior chemotherapy administration), and the effects of previous cancer management strategies such as radiotherapy and surgery.


2020 ◽  
pp. 003022282094508
Author(s):  
Eylem Pasli Gurdogan ◽  
Berna Aksoy ◽  
Ezgi Kinici

This study was conducted to examine the importance of the concept of a good death and the contributing factors from the perspectives of family caregivers of advanced cancer patients. This descriptive and cross-sectional study, conducted with 182 family caregivers, were collected using a questionnaire form and the “Good Death Scale”. The number and percentage distribution, multiple linear regression were used evaluation of data. The total score of the Good Death Scale was 62.65 ± 4.60. The factors contributing to the importance of the concept of a good death were determined as the presence of chronic disease; the type of treatment given to the patient; the presence of another family member who was previously diagnosed with cancer; the presence of a family member who has died of cancer and previously caregiving to a terminally ill family member. This study revealed that the concept of a good death is seen as very important.


2017 ◽  
Vol 11 (12) ◽  
pp. 4789
Author(s):  
Lóris Aparecida Prado da Cruz ◽  
Thais De Oliveira Gozzo ◽  
Laleska Andres Costa Santos

RESUMOObjetivo: identificar o conhecimento dos profissionais da equipe de Enfermagem acerca da prevenção e manejo do extravasamento de drogas quimioterápicas durante o tratamento oncológico. Método: estudo quantitativo, descritivo e transversal, com 16 profissionais da equipe de Enfermagem que atuam em um hospital no interior do Estado de São Paulo (SP), Brasil. Utilizou-se um questionário autoaplicável composto por variáveis sociodemográficas, questões sobre o tempo de exercício profissional, tempo de atuação na área oncológica e treinamentos sobre administração de quimioterápicos. Resultados: observou-se que 62,5% dos profissionais não sabiam a ordem de escolha da punção periférica; 12,5%, que agentes quimioterápicos não podem ser administrados em membros com alterações motoras; 43,7%, que o aumento da resistência da infusão é um sinal indicativo de extravasamento; 75% desconhecem o uso da compressa quente para determinados quimioterápicos e 87,5% referiram que conhecem o protocolo de extravasamento da instituição. Conclusão: nota-se a necessidade de estruturação de um programa de educação permanente devido à carência de conhecimentos técnicos e científicos acerca da prevenção e manejo do extravasamento por drogas quimioterápicas. Descritores: Enfermagem; Conhecimento; Quimioterapia.ABSTRACTObjective: to identify the knowledge of the professionals of the Nursing team about the prevention and management of extravasation of chemotherapy drugs during cancer treatment. Method: a quantitative, descriptive and cross-sectional study with 16 Nursing professionals working in a hospital in the interior of the state of São Paulo (SP), Brazil. A self-administered questionnaire was used, composed of socio-demographic variables, questions about professional practice time, oncological activity time and training on chemotherapy administration. Results: it was observed that 62.5% of the professionals did not know the order of choice of the peripheral puncture; 12.5%, that chemotherapeutic agents can not be administered to limbs with motor alterations; 43.7%, that increased infusion resistance is an indication of extravasation; 75% are unaware of the use of the hot compress for certain chemotherapeutic agents; and 87.5% reported knowing the institution's extravasation protocol. Conclusion: there is a need for structuring a permanent education program due to the lack of technical and scientific knowledge about the prevention and management of extravasation by chemotherapeutic drugs. Descriptors: Nursing; Knowledge; Drug Therapy.RESUMENObjetivo: identificar el conocimiento de los profesionales del equipo de Enfermería acerca de la prevención y manejo de la extravasación de drogas quimioterápicas durante el tratamiento oncológico. Método: estudio cuantitativo, descriptivo y transversal, con 16 profesionales del equipo de Enfermería que actúan en un hospital en el interior del Estado de São Paulo (SP), Brasil. Se utilizó un cuestionario auto aplicable compuesto por variables sociodemográficas, cuestiones sobre el tiempo de ejercicio profesional, tiempo de actuación en el área oncológica y entrenamientos sobre administración de quimioterápicos. Resultados: se observó que el 62,5% de los profesionales no sabían el orden de elección de la punción periférica; 12,5%, que agentes quimioterápicos no pueden ser administrados en miembros con alteraciones motoras; 43,7%, que el aumento de la resistencia de la infusión es un signo indicativo de extravasación; 75% desconocen el uso de la compresa caliente para determinados quimioterápicos; y el 87,5% señaló que conocen el protocolo de extravasación de la institución. Conclusión: se nota la necesidad de estructuración de un programa de educación permanente debido a la carencia de conocimientos técnicos y científicos acerca de la prevención y manejo de la extravasación por drogas quimioterápicas. Descriptores: Enfermería; Conocimiento; Quimioterapia.


2020 ◽  
Vol 4 (1) ◽  
pp. 1-5
Author(s):  
Ananda Purnama Mazna

Cancer is a disease characterized by abnormal cell growth outside the usual boundary then attacks the adjacent body and can spreads to other organs. Cancer treatment can be done with several therapies according to indications, one of them is radiotherapy. One of succession factor in the radiotherapy treatment for cancer is having good knowledge. Treatment adherence is very important to get optimal results such as healing or improving quality of life. The aim of this research was to determine the relationship between radiotherapy knowledge with radiotherapy adherence in undergoing radiotherapy cancer patients at General Hospital of Abdul Wahab Sjahranie Samarinda . This research was an observational analytic design with cross-sectional approach. Data retrieval was done at the Radiotherapy Installation at General Hospital of Abdul Wahab Sjahranie Samarinda from March to April 2019 by using a purposive sampling technique. The results showed that there were 50 samples who met the inclusion and exclusion criteria with details of patients who had good knowledge was 33 people, sufficient knowledge was 15 people, bad knowledge was 2 people and obey patients was 46 people and disobey patients was 4 people. Data analysis using Fisher's test obtained the value of p = 0.157 so it can be concluded that there was no relationship between radiotherapy knowledge and radiotherapy adherence in cancer patients at Radiotherapy Installation at General


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