scholarly journals Cell Types, Morphology and Evolution of Animal Excretory Organs

2020 ◽  
Author(s):  
Carmen Andrikou ◽  
Ludwik Gąsiorowski ◽  
Andreas Hejnol
Keyword(s):  
Spatial Arrangement ◽  
Cell Types ◽  
The Body ◽  
Toxic Waste ◽  
Waste Products ◽  
Functional Perspective ◽  
Additional Cell ◽  
And Control ◽  
Excretory Cell ◽  
Excretory Organs

Excretion and osmoregulation are fundamental processes of the organism, as they prevent the accumulation of toxic waste products in the body and control the osmotic differences between the cells and the environment. In most of the animals these phenomena are taking place through specialized organs, namely excretory organs, composed of diverse cell types that are performing tasks such as secretion and ultrafiltration. Although the morphology and embryology of excretory organs can differ dramatically, the common spatial arrangement of structural proteins and transporters as well as the similar transcriptional developmental programs underlying their formation suggests the homology of their cell types. In this chapter we discuss the current understanding of the evolution of excretory organsfrom a comparative morphological, developmental and functional perspective, flanked by an additional, cell-type perspective. We argue that a putative homologization of certain excretory cell types does not necessarily reflect the homology of the resulting organs, and that integrating all different levels of comparison is crucial for addressing evolutionary questions.

Immunological changes accompanying the development of experimental neoplastic process

2015 ◽  
Vol 6 (2) ◽  
pp. 96-108
Author(s):  
Elena Aleksandrovna Dementeva ◽  
Olga Petrovna Gurina
Keyword(s):  
Immune Response ◽  
Immune System ◽  
Genome Stability ◽  
Cell Types ◽  
Transformation Process ◽  
The Body ◽  
Expression Of Genes ◽  
Neoplastic Process ◽  
And Control ◽  
Different Cell Types

The key immunology problem remains the understanding of the mechanisms for the effective protection of the body against various pathogens with simultaneous suppression of the immune response to autoantigens. The pathogenesis of neoplastic pathological processes includes violations of the mechanisms of normal cell growth and cell proliferation. Antitumor immune response is a complex event, involving many different cell types. But despite the ability of the immune system to recognize and respond to a variety of tumor-associated antigens, the neoplastic process overcomes the protective forces of the organism, grows and spreads. For cancer cells characterized by independence from antiproliferative signals, autocrine stimulation of growth disturbances in the system, induction of apoptosis and control of genome stability. As a result of accumulation of genetic and epigenetic changes in tumor cells differ significantly from the normal range and the level of expression of genes involved in the transformation process, the accumulation of mutations in key genes promoters and suppressors of tumorigenesis. This creates the opportunity for recognition by cells of the immune system. The study of changes in value and operation of the various elements of the immune system in the development of experimental neoplastic process allows you to identify the mechanisms of interaction in the system «malignant tumor-immune system, to assess patterns of interaction with other organs and tissues, to create a theoretical pathogenetically reasonable premise for the development of anticancer therapy.

2. Energy

2021 ◽  
pp. 16-40
Author(s):  
Jamie A. Davies
Keyword(s):  
Carbon Dioxide ◽  
Energy Harvesting ◽  
Chemical Reactions ◽  
Human Cells ◽  
The Body ◽  
Waste Products ◽  
Body Function ◽  
Large Organism ◽  
Excretory Organs ◽  
Physiological Systems

This chapter focuses on energy as just one aspect of body function. The chapter describes the energy-harvesting chemical reactions which happen in all human cells. For them to be possible, these cells must have access to glucose and oxygen, and must be able to dispose of the waste products, carbon dioxide and water. In a large organism such as a human, even these apparently simple requirements are challenging and are met by a complex set of physiological systems, in particular the digestive, respiratory, cardiovascular, and excretory organs of the body.

Brain, Spinal Cord, and Sensory Systems

2019 ◽  
pp. 738-812
Author(s):  
Martin Brüne
Keyword(s):  
Spinal Cord ◽  
Human Brain ◽  
Sensory Systems ◽  
The Body ◽  
Toxic Waste ◽  
Waste Products ◽  
Social Challenges ◽  
Inhibitory Mechanisms ◽  
Incoming Information ◽  
Survival And Reproduction

The central nervous system (CNS) comprising the brain and the spinal cord is the control system of bodily functions and processes incoming information from the external environment via diverse sensory systems. Incoming information from the body (interoception) and from the environment (exteroception) is integrated and utilised in complex patterns of action and re-action (allostasis) to maintain homoeostasis and ensure survival and reproduction. The brains of primates are larger than expected for their body weight, whereby the human brain is not exceptional in terms of the number of neurons. However, connectivity and cross-talk between different brain areas has increased during human evolution. The adult human brain consumes about 20% of total energy intake, which is needed to maintain complex excitatory and inhibitory mechanisms with the aid of glia cells and microglia. Abnormal amounts of stress during different stages of development may expose the CNS to an excess of toxic and inflammatory metabolic products, which may cause neuropsychiatric disease and disorders. Such stressors may include, among other factors, adverse events such as abuse or neglect during childhood, immunological mismatches between ancestral and current environments, and a plethora of social challenges related to ‘modern’ cultural peculiarities. Gene–environment interactions involved in CNS disease processes are far from being fully understood. Preventive measures to protect the CNS from premature functional deterioration may include safe-guarding child development, a reduction of toxic waste products, and mental and physical exercise.

scholarly journals Preliminary Research of Relationship between Acute Peritonitis and Celiac Primo Vessels

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Xiaoyu Wang ◽  
Hong Shi ◽  
Jingjing Cui ◽  
Wanzhu Bai ◽  
Wei He ◽  
...  
Keyword(s):  
Cell Types ◽  
The Body ◽  
Immunofluorescent Staining ◽  
Intercellular Adhesion Molecule ◽  
Intercellular Adhesion Molecule 1 ◽  
E Coli ◽  
Acute Peritonitis ◽  
The Difference ◽  
And Control ◽  
Peritonitis Model

Previous studies demonstrated that primo vessels (PVs) were distributed in different parts of the body in mammals, and PVs were also involved in some processes of pathology such as cancer. Whether PVs are intrinsic structures in mammals or not is still ignored. In this study, a peritonitis model rat was induced by i.p. administration ofE. coliin rats. PVs were observed in all infected rats, but it appeared less in untreated rats, taking 10.53% (4/38). In addition, we examined cell types in celiac PVs by fluorescent staining with 4′,6-diamidino-2-phenylindole (DAPI) and Alexa Fluor 488 phalloidin, as well as immunofluorescent staining with CD11b and intercellular adhesion molecule-1(ICAM-1), and found the following. (1) The rod-shaped nuclei aligned longitudinally along PVs. (2) DAPI-, phalloidin-, CD11b-, and ICAM-1-positive labeling coexisted in PVs, suggesting that fibroblasts and leucocytes might be two kinds of cell types in PVs for both infected and control rats. (3) The difference was that numerous cells in PVs of the infected rats contained DAPI-labeled multilobal nucleus and were expressed with CD11b- and ICAM-1-positive labeling on the cytoplasm and membrane, showing the typical characteristics of neutrophil. (4) The cells in PVs from the untreated rats are those of loose connective tissue. Therefore, it is reasonably considered that PVs from infected rats might be the pathological products which might be involved in inflammation.

scholarly journals Role of Riyazat in prevention and control of lifestyle diseases: A review

2020 ◽  
Vol 10 (1-s) ◽  
pp. 211-214
Author(s):  
Yasra Farooqui ◽  
Mohd Yunus Siddiqui ◽  
Amreen Zehra ◽  
Maryam Zafar
Keyword(s):  
Good Health ◽  
The Body ◽  
Waste Products ◽  
Mortality And Morbidity ◽  
Beneficial Effects ◽  
Bodily Movement ◽  
Obesity Hypertension ◽  
Lifestyle Diseases ◽  
And Control

Background: Riyazat (exercise) is a planned, structured and repetitive bodily movement that is done to improve or maintain physical fitness and overall health. It plays an important role not only in maintaining good health but also in preventing and curing certain ailments as well. Lifestyle diseases are ailments that are primarily based on the day to day habits of people. Lack of exercise and habits that detract people from the activity and push them towards a sedentary routine, these are the major causes which serve as an important factor in the rising prevalence of lifestyle diseases. Some of the emerging lifestyle diseases are obesity, hypertension, type 2 diabetes, cardiovascular diseases, joint diseases and psychological disorders. Mortality and morbidity rates have also increased with increasing levels of these diseases. Frequent and consistent exercise helps in the prevention of these diseases. It helps in maintaining or losing weight, improves metabolic function and mental health by reducing stress. Many ancient Unani physicians like Hippocrates, Galen, Razi and Avicenna have discussed the beneficial effects of riyazat in their treatise. Conclusion:  It is used as a regimental therapy that acts by inhibiting agglomeration of morbid material in the body and helps in revocation of waste products through natural routes, thus reducing risks for the development of various diseases. So there is an indispensable need to procure exercise regularly to forestall lifestyle diseases for the betterment of life. Keywords: Riyazat, metabolic, ancient, regimental, morbid

Perbandingan Efek Suplementasi Tablet Tambah Darah Dengan Dan Tanpa Vitamin C Terhadap Kadar Hemoglobin Pada Ibu Hamil Dengan Usiakehamilan 16-32 Minggu Di Desa Keniten Kecamatan Mojo Kabupaten Kediri

2017 ◽  
Vol 3 (1) ◽  
pp. 76
Author(s):  
Siti Asiyah ◽  
Dwi Estuning Rahayu ◽  
Wiranti Dwi Novita Isnaeni
Keyword(s):  
Treatment Group ◽  
Vitamin C ◽  
Gestational Age ◽  
Group Treatment ◽  
Sampling Technique ◽  
Hemoglobin Level ◽  
The Body ◽  
Control Group ◽  
Fetal Organ ◽  
And Control

The needed of Iron Tablet in pregnancy was increase than mother who not pregnant.  That  cause of  high metabolism at the pregnancy for formed of  fetal organ and energy. One of effort for prevent anemia in mother pregnant with giving the Iron tablet and vitamin c. The reason of  this research in 4 June – 11 July 2014 is for compare the effect of  iron tablet suplementation with and without vitamin C toward Hemoglobin level in mother pregnant With Gestational Age Of 16-32 Weeks In Desa Keniten Kecamatan Mojo Kabupaten Kediri. This research method using comparative analytical.  Research design type of Quasy Eksperiment that have treatment group and control group. Treatment group will giving by Iron tablet and 100 mg vitamin C, and control group just giving by iron tablet during 21 days. Population in this research are all of mother pregnant with Gestational Age Of 16-32 Weeks with Sampling technique is  cluster random sampling is 29 mother pregnant. Comparison analysis of  iron tablet suplementation effect with and without vitamin C toward Hemoglobin level in mother pregnant With Gestational Age Of 16-32 Weeks, data analysis using Mann Whitney U-test and the calculated U value (44,5) less than U-table (51). So there was difference of iron tablet suplementation effect with and without vitamin C toward Hemoglobin level in mother pregnant With Gestational Age Of 16-32 Weeks Therefore, the addition of vitamin C on iron intake is needed to increase the uptake of iron tablets. When the amount of iron uptake increases, the reserves of iron in the body will also increase, so as to prevent anemia in pregnant women; Keywords : Iron Tablet (Fe), Vitamin C, Hemoglobin level, Mother Pregnant

In-vivo evaluation of lipid lowering ability of Chloris paraguaiensis extracts

2020 ◽  
Vol 7 (2) ◽  
pp. 21-24
Author(s):  
Pavani C H
Keyword(s):  
Medicinal Plants ◽  
Chemical Constituents ◽  
The Body ◽  
Lipid Lowering ◽  
Medical Systems ◽  
In Vivo Evaluation ◽  
Standard Drug ◽  
Anti Oxidant ◽  
And Control

Hyperlipidemia is the immediate results of the excessive fat intake in food. This results in the elevated levels of cholesterol and triglycerides in the blood. This leads to heart conditions like CAD, hypertension, congestive heart failure as risk factors which can be lethal. There are many drugs to treat and control the lipids levels in the body. These drugs are either designed to prevent LDL accumulation and VLDL synthesis. Some drugs also lower the elevated levels of saturated lipids in the body. But many drugs are known to cause side effects and adverse effects; therefore, alternatives to the drugs are the subjects for current investigations. Herbs and medicinal plants are used as treatment sources for many years. They have been used in the Indian medical systems like Ayurveda, Siddha etc. As the application of herbs in the treatment is growing, there is an urgent need for the establishment of Pharmacological reasoning and standardization of the activity of the medicinal plants. Chloris paraguaiensis Steud. is Poyaceae member that is called locally as Uppugaddi. Traditionally it is used to treat Rheumatism, Diabetes, fever and diarrhoea. The chemical constituents are known to have anti-oxidant properties and most of the anti-oxidants have anti-hyperlipidemic activity too. Since the plant has abundant flavonoid and phenol content, the current research focusses on the investigation of the anti-hyperlipidemic activity of the plant Chloris extracts. Extracts of Chloris at 200mg/kg showed a comparably similar anti hyperlipidemia activity to that of the standard drug. The extracts showed a dose based increase in the activity at 100 and 200mg/kg body weight.

Role of Rasayana in Prevention of COVID-19 - A Review

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 716-722
Author(s):  
Sneha Dhakite ◽  
Sadhana Misar Wajpeyi
Keyword(s):  
Immune System ◽  
Respiratory System ◽  
Viral Infections ◽  
Cost Effective ◽  
The Body ◽  
Healthy Life ◽  
Vital Functions ◽  
Healthy Life Style ◽  
And Control

The “Coronavirus disease 19 (COVID-19)” is caused by “Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)”, a newly discovered member of the Coronaviridae family of viruses which is a highly communicable. There is no effective medical treatment till date for Coronavirus disease hence prevention is the best way to keep disease away. Rasayana proved to be highly efficacious and cost effective for the Prevention and Control of viral infections when vaccines and standard therapies are lacking. Rasayana Chikitsa is one of the eight branches of Ashtanga Ayurveda which helps to maintain healthy life style. Rasayana improves immunity and performs many vital functions of human body. Vyadhikshamatva that is immune mechanism of the body is involved in Prevention of the occurrence of a new disease and it also decreases the virulence and progression of an existing disease. In COVID-19 the Respiratory system mainly get affected which is evident from its symptoms like cold, cough and breathlessness. Here the drugs help in enhancing immune system and strengthening functions of Respiratory system can be useful. For this purpose, the Rasayana like Chyavanprasha, Agastya Haritaki, Pippali Rasayana, Guduchi, Yashtimadhu, Haridra, Ashwagandha, Tulsi are used. Rasayana working on Respiratory system are best for Prevention of Coronavirus and boosting immune system. Rasayana Chikitsa can be effective in the Prevention as well as reducing symptoms of COVID-19.

scholarly journals Extracellular-Vesicle-Based Coatings Enhance Bioactivity of Titanium Implants—SurfEV

Nanomaterials ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1445
Author(s):  
Taisa Nogueira Pansani ◽  
Thanh Huyen Phan ◽  
Qingyu Lei ◽  
Alexey Kondyurin ◽  
Bill Kalionis ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Titanium Surface ◽  
Wound Closure ◽  
Cell Types ◽  
Extracellular Vesicle ◽  
Tissue Growth ◽  
Titanium Implants ◽  
The Body ◽  
High Concentrations ◽  
And Migration

Extracellular vesicles (EVs) are nanoparticles released by cells that contain a multitude of biomolecules, which act synergistically to signal multiple cell types. EVs are ideal candidates for promoting tissue growth and regeneration. The tissue regenerative potential of EVs raises the tantalizing possibility that immobilizing EVs on implant surfaces could potentially generate highly bioactive and cell-instructive surfaces that would enhance implant integration into the body. Such surfaces could address a critical limitation of current implants, which do not promote bone tissue formation or bond bone. Here, we developed bioactive titanium surface coatings (SurfEV) using two types of EVs: secreted by decidual mesenchymal stem cells (DEVs) and isolated from fermented papaya fluid (PEVs). For each EV type, we determined the size, morphology, and molecular composition. High concentrations of DEVs enhanced cell proliferation, wound closure, and migration distance of osteoblasts. In contrast, the cell proliferation and wound closure decreased with increasing concentration of PEVs. DEVs enhanced Ca/P deposition on the titanium surface, which suggests improvement in bone bonding ability of the implant (i.e., osteointegration). EVs also increased production of Ca and P by osteoblasts and promoted the deposition of mineral phase, which suggests EVs play key roles in cell mineralization. We also found that DEVs stimulated the secretion of secondary EVs observed by the presence of protruding structures on the cell membrane. We concluded that, by functionalizing implant surfaces with specialized EVs, we will be able to enhance implant osteointegration by improving hydroxyapatite formation directly at the surface and potentially circumvent aseptic loosening of implants.

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