scholarly journals Genetic Risks and Demographic History of Indigenous Goats of Mongolia Revealed by SNP Genotyping

Author(s):  
Alexey Piskunov ◽  
Vera Mukhina ◽  
Gulnara Svishcheva ◽  
Valery Voronkova ◽  
Yurii Stolpovsky

Recent climatic disasters (dzudzs) and uncontrolled massive breeding endangered valuable ge-netic resources of Mongolian goats labored by five thousand years of evolution in extremes of Al-tai mountains and Gobi deserts. Meanwhile, Mongolian goats has never been characterized by genomic data. We used Illumina Goat SNP50 to investigate phylogenic relationships and genetic risks in 5 local Mongolian populations: Erchim (N=37) from geographically remote Darkhat Valley in the northern mountains, Ulgii Red (N=35) and Dorgon (N=28) from the western mountain region, Buural (N=34) from the western steppe and mountain areas and Gobi Gurvan Saikhan (N=33) from semi-arid steppe area in the South Gobi region. ROH analyses, estimated populations sizes and Fst values showed South Gobi and Darkhat Valley goats to be of a high risk of inbreed-ing that however appear to be of distinct origin (artificial selection vs geographical isolation). In-dices of genetic differentiations between Mongolian goats were relatively low compared to Euro-pean breeds. Meanwhile, we suggest direct comparison is not fully appropriate given that Mongo-lian breeds were not subjected to intense selection. Darkhat Valley goats were clearly differentiat-ed from other Mongolian breeds according to various types of analyses. Phylogenetic relationships within XXX breeds of the rest of the world plotted Mongolian goats between some Russian (Altai, Orenburg) and Chinese populations (Nanjiang and Qinggeli). Thus, present study (i) highlights demographic history Mongolian goats and (ii)provides unified SNP-data called for support deci-sions in conservational genetics. Finally, our work (iii) raises a question of how exactly these data should be compared to make objective choices.

2021 ◽  
Vol 53 (1) ◽  
Author(s):  
Fan Jiang ◽  
Ruiyi Lin ◽  
Changyi Xiao ◽  
Tanghui Xie ◽  
Yaoxin Jiang ◽  
...  

Abstract Background The most prolific duck genetic resource in the world is located in Southeast/South Asia but little is known about the domestication and complex histories of these duck populations. Results Based on whole-genome resequencing data of 78 ducks (Anas platyrhynchos) and 31 published whole-genome duck sequences, we detected three geographic distinct genetic groups, including local Chinese, wild, and local Southeast/South Asian populations. We inferred the demographic history of these duck populations with different geographical distributions and found that the Chinese and Southeast/South Asian ducks shared similar demographic features. The Chinese domestic ducks experienced the strongest population bottleneck caused by domestication and the last glacial maximum (LGM) period, whereas the Chinese wild ducks experienced a relatively weak bottleneck caused by domestication only. Furthermore, the bottleneck was more severe in the local Southeast/South Asian populations than in the local Chinese populations, which resulted in a smaller effective population size for the former (7100–11,900). We show that extensive gene flow has occurred between the Southeast/South Asian and Chinese populations, and between the Southeast Asian and South Asian populations. Prolonged gene flow was detected between the Guangxi population from China and its neighboring Southeast/South Asian populations. In addition, based on multiple statistical approaches, we identified a genomic region that included three genes (PNPLA8, THAP5, and DNAJB9) on duck chromosome 1 with a high probability of gene flow between the Guangxi and Southeast/South Asian populations. Finally, we detected strong signatures of selection in genes that are involved in signaling pathways of the nervous system development (e.g., ADCYAP1R1 and PDC) and in genes that are associated with morphological traits such as cell growth (e.g., IGF1R). Conclusions Our findings provide valuable information for a better understanding of the domestication and demographic history of the duck, and of the gene flow between local duck populations from Southeast/South Asia and China.


Insects ◽  
2020 ◽  
Vol 11 (2) ◽  
pp. 111 ◽  
Author(s):  
Xueting Sun ◽  
Jing Tao ◽  
Alain Roques ◽  
Youqing Luo

Sirex noctilio F. (Hymenoptera: Siricidae: Siricinae), a new invasive species in China, is a significant international forestry pest which, transported via logs and related wood packing materials, has led to environmental damage and substantial economic loss in many countries around the world. It was first detected in China in 2013, and since then infestations have been found in 18 additional sites. Using a 322 bp fragment of the mitochondrial barcode gene COI, we studied the genetic diversity and structure of S. noctilio populations in both native and invaded ranges, with a specific focus in China. Twelve haplotypes were found across the native and invaded distribution of the pest, of which three were dominant; among these there were only one or two mutational steps between each pair of haplotypes. No obvious genetic structure was found other than in Chinese populations. China has a unique and dominant haplotype not found elsewhere, and compared with the rest of the world, the genetic structure of Chinese populations suggested a multiple invasion scenario.


2019 ◽  
Vol 64 (2) ◽  
pp. 309-323
Author(s):  
Pim de Zwart

Inequality has increased in most Western countries since the early 1980s. In a recent report, the international non-governmental organization Oxfam noted that the twenty-six richest people in the world own as much wealth as the poorest fifty per cent of the world's population. Discontent with the growing disparities in wealth and income has soared in recent years, especially in the wake of the 2007/2008 financial crisis and the “Great Recession” that followed. The Occupy movement protested against the greed of the “one per cent”, referring to the highly skewed income distribution in the US. Former US president Barack Obama proclaimed the growth of within-country economic inequality as “the defining challenge of our time”. Yet, he enacted few policies that reduced inequality during his two terms in office; the Gini coefficient in the US actually increased slightly between 2007 and 2016. His successor, whose election has often been explained as a consequence of these high levels of inequality, has slashed taxes for the wealthy, probably causing further rises in inequality in the future. In this essay, I will review two recent economic history books that examine the historical roots of within-country inequality on a global scale: Branko Milanovic's Global Inequality (2016) and Walter Scheidel's The Great Leveler (2017). Formerly a lead economist at the World Bank, Milanovic is a well-known scholar working in the field of economic inequality, while Scheidel has a background as a specialist in the economic, social, and demographic history of antiquity.


The changing character of immigration over time in Tripura led to a huge demographic transition which is rare in the demographic history of the world. The study attempted to assess the distribution of documented Bangladeshi immigrants in Tripura and measure the trend and pattern of Bangladeshi immigration in the state. The study was based on secondary data computed from the migration tables under the D-series of census reports (1991,2001 and 2011) to deal with the study's objectives. The study has explored that almost 99 per cent of the total reported immigrants were from Bangladesh. The results revealed that female counterparts had outstripped the male Bangladeshi immigrants while the overall size of the immigrants was diminishing.


Heredity ◽  
2021 ◽  
Author(s):  
Kristy Mualim ◽  
Christoph Theunert ◽  
Montgomery Slatkin

AbstractWe present a method called the G(A|B) method for estimating coalescence probabilities within population lineages from genome sequences when one individual is sampled from each population. Population divergence times can be estimated from these coalescence probabilities if additional assumptions about the history of population sizes are made. Our method is based on a method presented by Rasmussen et al. (2014) to test whether an archaic genome is from a population directly ancestral to a present-day population. The G(A|B) method does not require distinguishing ancestral from derived alleles or assumptions about demographic history before population divergence. We discuss the relationship of our method to two similar methods, one introduced by Green et al. (2010) and called the F(A|B) method and the other introduced by Schlebusch et al. (2017) and called the TT method. When our method is applied to individuals from three or more populations, it provides a test of whether the population history is treelike because coalescence probabilities are additive on a tree. We illustrate the use of our method by applying it to three high-coverage archaic genomes, two Neanderthals (Vindija and Altai) and a Denisovan.


Author(s):  
Francisco Vidal Luna ◽  
Herbert S. Klein

This volume is the continuation of an earlier study of colonial and imperial São Paulo and covers the period 1850-1950. These volumes are the first full scale survey of the economy and society of the state of São Paulo in this two century period in any language. Today São Paulo is the most populated state of Brazil and also the richest and most industrialized one. It is also the world leader in the production of sugar cane and orange juice and houses one of the world’s major airplane manufacturers. Its GDP today is almost double the size of Portugal or Finland and close to the size of the entire economy of Colombia or Venezuela and its capital city is one of the top five metropolitan centers in the world. This volume shows how the region of São Paulo went from being one of the more marginal and backward areas of the nation to its leading agricultural, industrial and financial center. Special emphasis is given to the creation of a modern state government and finances in the late 19th and early 20th centuries as well as the evolution of tis coffee economy and its internal market as well as its leading role it played in the integration of over two million European and Asian immigrants into Brazilian society.


POPULATION ◽  
2021 ◽  
Vol 24 (2) ◽  
pp. 142-153
Author(s):  
Vladimir Tetelmin

The continuous increase in human energy production per caput is accompanied by an increase in the world population. The work considers the demographic history of civilization as a function of the growing production and use of the energy by mankind. The evolution in the «energy-man» system took place relatively safely for the biosphere and a man up to the value of the per caput energy consumption of 11,000 kW*h/year*person that was achieved by civilization in 1950. Modern high per caput energy consumption of civilization is achieved at the cost of the loss of the environment-forming functioning by the biosphere and at the cost of the loss of the psychophysical health of a person. We can see the prospects for development of civilization through analysis of the energy-demographic history of mankind over the past 200 years. The features of fertility and mortality in the world are considered depending on the per caput energy consumption with a forecast for the future. Two limits to the growth of global energy production were formulated in terms of preventing harm to humans. Corresponding analytical dependencies are proposed. To prevent an ecological and demographic catastrophe and ensure transition of civilization to sustainable development, it is proposed to reduce the world energy production to 140*1012 kW*h/year with a decrease in per caput energy consumption to a relatively safe level of 18,000 kW*h/year*person, which existed in society in 1970. After this «step back» civilization will enter a state of relatively safe existence.


Author(s):  
Meri Badalyan ◽  
Lusine Karapetyan

This article is dedicated to the study of the interrelation between the education level of women and the birth rate. One of the essential lessons in the demographic history of the world countries is that the high birth rate recorded during the last century was temporary; it is already evident that the world birth rate has halved and tends to decline further. The level of education and employment of women are among the factors that underlie the decrease in the birth rate. Numerous studies prove that this relation is reversed. Like some other countries in the world, there is narrow reproduction in Armenia, which is mainly caused by changes in the education level, employment, mindset of women and their role in the family.


2020 ◽  
Vol 98 (Supplement_4) ◽  
pp. 450-450
Author(s):  
Tatiana Evgenievna Deniskova ◽  
Arsen V Dotsev ◽  
Marina I Selionova ◽  
Margaret S Fornara ◽  
Henry Reyer ◽  
...  

Abstract Specific environmental conditions and local livestock management systems resulted in creation of valuable native breeds. The timely monitoring of genetic diversity within native breeds based on using high-throughput DNA arrays will prevent their irreparable loss. In this regard, we aimed to assess genome-wide diversity and to study demographic history of Russian native goat breeds (Altai Mountain, Orenburg, Soviet Mohair, Dagestan Milk, Dagestan Local, Dagestan Fluff and Karachaev) based on SNP-data. A total of 200 goats were genotyped using Goat 50K SNP BeadChip (Illumina, USA). Quality control and SNP-filtering were performed in PLINKv1.9. R package ‘diveRsity’ was used to calculate observed heterozygosity (Ho), expected heterozygosity (He), and inbreeding coefficient (Fis). Effective population sizes (Ne) were estimated in SneP software. Observed heterozygosity was high and exceeded 0.402 in five out of seven breeds. Orenburg, Soviet Mohair, Dagestan Milk, and Karachaev breeds showed slight excess of heterozygotes varied from 0.6% (Fis= -0.015) in Orenburg to 1.7% (Fis= -0.04) in Karachaev breed. The traces of insignificant inbreeding were found in Dagestan Local (Fis=0.005) and Dagestan Fluff (Fis= 0.01) breeds. The recent effective population sizes estimated for four generations ago varied from 140 in Karachaev to 472 in Orenburg breed. Analysis of historical trends in effective population sizes estimated for sixty generations ago revealed obvious decrease ranging from 10.25% in Dagestan Local to 34.65% in Orenburg breed. However, recent effective sizes in Russian native goats are higher than critical threshold (Ne= 100) that is essential to breed maintenance in the future. Our research findings provide an evidence that Russian native goat breeds are not in endangered status, but development of the effective utilization programs is highly recommended. The genotyping of 96 goats was funded by RSF No. 19-76-20006. The reported study was funded by RFBR according to the research project № 18-316-20006.


IEE Review ◽  
1991 ◽  
Vol 37 (10) ◽  
pp. 355
Author(s):  
D.A. Gorham

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