Clinical features and mortality-related factors of extensive burns among young adults: the Kunshan disaster experience

Abstract Background To observe the effect of corticosteroids in the treatment of children with refractory Mycoplasma pneumoniae pneumonia (RMPP) under different doses, to summarize the clinical features of children treated with glucocorticoid pulse therapy. Methods The clinical data of 125 children with RMPP hospitalized in Tianjin Children’s Hospital from September 2018 to October 2019 were retrospectively analyzed. They were divided into two groups according to the dose of hormone. Compare the clinical features, laboratory findings, and imaging between the two groups, and use meaningful related indicators as ROC curves to find reference indicators for pulse therapy. Results (1) The median age of the group II was older than that of the group I(P < 0.05). (2) We found more severe presentations, higher incidence of extra-pulmonary complications and more serious radiological findings in group II, which needed oxygen more often, higher the hormone, higher usage rate of gamma globulin, higher usage rate of bronchoscopy, and higher incidence of plastic bronchitis(P < 0.05). (3) WBC, CRP, LDH, FER, D-D dimer, APTT, TT, PCT, IL-6 and the percentage of neutrophils in peripheral blood in Group II were higher than those in Group I(P < 0.05). (4) In ROC curve analysis, CRP, LDH, FER, and neutrophils of leukocyte classification were independent related factors that could be used as valuable predictors of methylprednisolone pulse therapy for RMPP in children. The cut-off values were CRP44.45 mg/L, LDH590IU/L, FER411ng/L, and neutrophils in leukocyte classification were 73.75%, respectively. Conclusion CRP ≥ 44.45 mg/L, LDH ≥ 590 IU/L, FER ≥ 411 ng/L, neutrophil≥73.75%, lung consolidation, and pleural effusion may be predictors that guide the treatment of RMPP with pulse dose of GC.

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Risk Factors for Disability Pension among Young Adults Diagnosed with Attention-deficit Hyperactivity Disorder (ADHD) in Adulthood

Journal of Attention Disorders ◽

10.1177/10870547211025605 ◽

2021 ◽

pp. 108705472110256

Author(s):

Lingjing Chen ◽

Ellenor Mittendorfer-Rutz ◽

Emma Björkenstam ◽

Syed Rahman ◽

Klas Gustafsson ◽

...

Keyword(s):

Risk Factors ◽

Young Adults ◽

Disability Pension ◽

Cox Regression ◽

Related Factors ◽

Adult Age ◽

Work Related ◽

Hyperactivity Disorder ◽

Increased Risk ◽

Similar Risk

Objective: To investigate risk factors of disability pension (DP) in young adults diagnosed with ADHD in Sweden. Method: In total, 9718 individuals diagnosed with incident ADHD in young adult age (19–29 years) 2006 to 2011, were identified through national registers. They were followed for 5 years and Cox regression models were applied to analyze the DP risk (overall and by sex), associated with socio-demographics, work-related factors, and comorbid disorders. Results: Twenty-one percent of all received DP. Being younger at diagnosis (hazard ratio [HR] = 1.54; 95%confidence interval [CI] 1.39–1.71); low educational level (HR = 1.97; 95%CI 1.60–2.43 for <10 years); work-related factors at baseline (no income from work [HR = 2.64; 95%CI 2.35–2.98] and sickness absence >90 days [HR = 2.48; 95%CI2.17–2.83]); and schizophrenia/psychoses (HR = 2.16; 95%CI 1.66–2.80), autism (HR = 1.87; 95%CI 1.42–2.46), anxiety (HR = 1.34; 95%CI 1.22–1.49) were significantly associated with an increased risk of DP. Similar risk patterns were found in men and women. Conclusion: Work-related factors and comorbid mental disorders need to be highlighted in early vocational rehabilitation for individuals with ADHD.

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Clinical Features and Related Factors of Poststroke Pathological Laughing and Crying: A Case–Control Study

Journal of Stroke and Cerebrovascular Diseases ◽

10.1016/j.jstrokecerebrovasdis.2015.11.003 ◽

2016 ◽

Vol 25 (3) ◽

pp. 556-564 ◽

Cited By ~ 9

Author(s):

Geying Wang ◽

Fei Teng ◽

Yuhui Chen ◽

Yuanhua Liu ◽

Yancheng Li ◽

...

Keyword(s):

Clinical Features ◽

Case Control Study ◽

Case Control ◽

Related Factors ◽

Control Study

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Abstract MP009: Changes in Aldosterone are Associated With Changes in Obesity-Related Factors in Normotensive Overweight/Obese Young Adults Undergoing Lifestyle Modification

Circulation ◽

10.1161/circ.125.suppl_10.amp009 ◽

2012 ◽

Vol 125 (suppl_10) ◽

Author(s):

Jennifer Cooper ◽

Linda Fried ◽

Ping Tepper ◽

Emma Barinas-Mitchell ◽

Kim Sutton-Tyrrell

Keyword(s):

Insulin Resistance ◽

Blood Pressure ◽

Weight Loss ◽

Young Adults ◽

Lifestyle Modification ◽

Urinary Sodium ◽

Dietary Sodium ◽

Related Factor ◽

Related Factors ◽

Aldosterone Antagonists

Background: Elevated aldosterone promotes inflammation, insulin resistance, and hypertension. These effects are particularly important in obesity because adipocytes secrete factors that increase aldosterone production. Weight loss is thought to lower aldosterone levels, but little longitudinal data is available. We aimed to determine if, independent of changes in sodium intake, reductions in circulating aldosterone are associated with weight loss and improvements in inflammation, adipokines, insulin resistance, and blood pressure in normotensive overweight and obese young adults undergoing lifestyle modification. Methods: Participants were overweight/obese adults aged 20–45 years (20% male, 15% black) from the Slow Adverse Vascular Effects of excess weight trial, a study evaluating the relationships between weight loss, dietary sodium, and vascular health. Subjects were randomly assigned to a regular or reduced sodium diet, and all received a one-year nutrition and physical activity intervention. For this study, individuals providing valid baseline 24hr urine collections were included (n=281). Linear mixed models were used to evaluate associations between changes in aldosterone and changes in weight, blood pressure, and obesity-related factors. Results: Weight loss was significant at 6 months (∼7%), 12 months (∼6%), and 24 months (∼4%) (p<0.0001 for all). Within-subject decreases in aldosterone were associated with decreases in C-reactive protein, leptin, and homeostasis assessment of insulin resistance (HOMA-IR) and with increases in adiponectin (p<0.01 for all) in models including baseline age, sex, race, intervention arm, time since baseline, and baseline and concurrent changes in BMI, urinary sodium and potassium, and the obesity-related factor of interest. Decreases in aldosterone were associated with weight loss only in the subgroup (n=98) with metabolic syndrome (MetS) at baseline (MetS x percent weight loss p=0.02); a 10% weight reduction in this subgroup was associated with a 9% (95% CI 1–16) reduction in aldosterone. Though no association was detected between changes in aldosterone and mean arterial pressure (MAP), a significant association was found between reductions in MAP and 24hr urinary sodium in those with MetS (MetS x urinary sodium reduction p=0.02). Independent of weight loss, a 30% reduction in urinary sodium was associated with a 0.9 mm Hg (95% CI 0.2–1.6) decrease in MAP in those with MetS. Conclusions: Changes in aldosterone are associated with changes in obesity-related factors in overweight/obese normotensive young adults. In persons with MetS, weight loss and dietary sodium restriction are particularly useful to reduce aldosterone and MAP respectively. Given the adverse effects of excess aldosterone on cardiac and vascular remodeling, future studies should investigate the benefits of aldosterone antagonists in individuals with MetS.

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Clinical features and psychosocial factors in young adults with genital herpes

Image the Journal of Nursing Scholarship ◽

10.1111/j.1547-5069.1995.tb00808.x ◽

1995 ◽

Vol 27 (1) ◽

pp. 16-22 ◽

Cited By ~ 9

Author(s):

Janice M. Swanson ◽

Suzanne L. Dibble ◽

W. Carole Chenitz

Keyword(s):

Young Adults ◽

Psychosocial Factors ◽

Genital Herpes ◽

Clinical Features

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Tufted angioma in ear auricle: importance of the differential diagnosis

Anais Brasileiros de Dermatologia ◽

10.1590/abd1806-4841.20132538 ◽

2013 ◽

Vol 88 (6 suppl 1) ◽

pp. 113-115 ◽

Cited By ~ 4

Author(s):

Carla Andréa Avelar Pires ◽

Brena Andrade de Sousa ◽

Gabriela Athayde Amin ◽

Maraya de Jesus Semblano Bittencourt ◽

Mario Fernando Ribeiro de Miranda ◽

...

Keyword(s):

Young Adults ◽

Differential Diagnosis ◽

Clinical Features ◽

Male Patient ◽

Lepromatous Leprosy ◽

Vascular Proliferation ◽

Tufted Angioma ◽

Ear Auricle ◽

Histological Characteristics ◽

Children And Young Adults

Tufted angioma is an acquired vascular proliferation with specific histological characteristics. The most common clinical features are erythematous macules. It occurs predominantly in children and young adults, especially in the chest and neck. We report the case of a male patient, 12 years old, with an increased right ear auricle associated with erythematous macules and increased local temperature, referred with a diagnosis of lepromatous leprosy; however, this diagnosis was questioned. Histopathology was consistent with tufted angioma.

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Pán Péterek? - avagy létezik-e kapunyítási pánik a szakképzésből kikerülő fiataloknál - egy vizsgálat utóélete

Opus et Educatio ◽

10.3311/ope.307 ◽

2019 ◽

Vol 6 (2) ◽

Author(s):

Anna Kricsfalusi

Keyword(s):

Gender Differences ◽

Young Adults ◽

Life Cycle ◽

Emerging Adulthood ◽

Identity Status ◽

Peter Pan ◽

Related Factors ◽

Age Related ◽

Avoidance Strategy ◽

Key Questions

A tanulmány a Pán Péter Szindrómát, valamint a Kapunyitási Pánikot, az utóbbi évtized közkedvelt kifejezéseit és jelenségeit vizsgálja a felnőttkorba lépő, szakképzésből kikerülő fiatalok körében. Központi kérdései: Miért alakulhatott ki? Miért most? Létezik e valóban, vagy csak az elkerülési stratégiák egyik válfajáról van szó? Milyen jelenségek együttese okozza a kialakulását? Vannak- e életkori sajátosságok, amik hajlamosító tényezőkké válhatnak? Vannak-e nemi különbségek a jelenség megjelenésénél? A kérdések megválaszolásával próbálom igazolni, hogy Pán Péter szindróma helyett inkább egy speciális, életciklus váltás okozta krízis állapotról beszélhetünk. Kulcsszavak: Pán Péter szindróma, kapunyitási pánik, krízisállapot, quaterlife crisis, fiatalok, posztadoleszcencia, emerging adulthood, korszakváltás, identitás státusz, szorongás, elkerülési stratégia, depresszió Diszciplina: pszichológia, szociológia, neveléstudomány The study examines the Peter Pan Syndrome and the Quarterlife Crisis, two well-known phenomena which occur among young adults finishing their vocational training.The key questions are: Why do they happen? Why at this time? Do they really exist or are they just some types of avoidance strategies? What circumstances cause their emergence? Are there any age-related factors that may predispose their occurrence? Are there any gender differences in their appearance?Answering these questions I have come to the conclusion that instead of the Peter Pan Syndrome what we face is rather a special state of crisis caused by the life cycle transition. Keywords: Peter Pan Syndrome, quaterlife crisis, crisis status, young adults, post-adolescent, emerging adulthood, identity status, anxiety, avoidance strategy, depressionDisciplines: psychology, sociology, pedagogy

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Differential Associations of Coping Strategies With Grief and Depression in Young Adults: The Role of Cause of Death and Relationship to the Deceased

Journal of Social and Clinical Psychology ◽

10.1521/jscp.2020.39.3.172 ◽

2020 ◽

Vol 39 (3) ◽

pp. 172-194

Author(s):

Cyrille Kossigan Kokou-Kpolou ◽

Askar Jumageldinov ◽

Sunyoung Park ◽

Nicolas Nieuviarts ◽

Chama Khales ◽

...

Keyword(s):

Young Adults ◽

Depressive Symptoms ◽

Coping Strategies ◽

Clinical Manifestations ◽

Related Factors ◽

Counseling Interventions ◽

Persistent Complex Bereavement ◽

Identity Disruption ◽

Persistent Complex Bereavement Disorder ◽

The Impact

Introduction: The impact of loss by death in young adults has been underinvestigated, although higher rates of traumatic deaths are reported at this developmental stage. This study examined the relative differential consequences of bereavement-related factors for Persistent Complex Bereavement Disorder (PCBD) and depression. In addition, coping strategies predicting the study outcomes were examined as a function of bereavement-related factors. Methods: The study included 580 bereaved young adults with up to 5-year post loss. They were administered a battery of valided tools measuring PCBD symptoms, normal acute grief reactions as measured by the Core Bereavement Items scale, depressive symptoms, coping strategies, and bereavement-related characteristics. Covariance and regression analyses were used. Results: We found that the dimensions of PCBD and depressive symptoms were differentially associated with the bereavement-related factors. More specifically, the death of an immediate family member was associated with higher levels of PCBD-separation distress, whereas the traumatic death of a friend and romantic partner was more associated with PCBD-social and identity disruption. Furthermore, the study revealed differential associations between PCBD severity, depressive symptoms, and coping strategies as functions of bereavement-related factors. Discussion: The study has provided better understanding of clinical manifestations of PCBD as a function of etiologic risk factors. The results clarifying risk and protective factors are especially useful for improving effective bereavement-health counseling interventions among bereaved young adults.

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Adolescents' and Young Adults' Perception of Homosexuality and Related Factors in Three Asian Cities

Journal of Adolescent Health ◽

10.1016/j.jadohealth.2011.12.008 ◽

2012 ◽

Vol 50 (3) ◽

pp. S52-S60 ◽

Cited By ~ 30

Author(s):

Yongliang Feng ◽

Chaohua Lou ◽

Ersheng Gao ◽

Xiaowen Tu ◽

Yan Cheng ◽

...

Keyword(s):

Young Adults ◽

Adolescents And Young Adults ◽

Related Factors ◽

Asian Cities

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Associations of social environment, socioeconomic position and social mobility with immune response in young adults: the Jerusalem Perinatal Family Follow-Up Study

BMJ Open ◽

10.1136/bmjopen-2017-016949 ◽

2017 ◽

Vol 7 (12) ◽

pp. e016949 ◽

Cited By ~ 1

Author(s):

Gabriella M Lawrence ◽

Yehiel Friedlander ◽

Ronit Calderon-Margalit ◽

Daniel A Enquobahrie ◽

Jonathan Yinhao Huang ◽

...

Keyword(s):

Immune Response ◽

Young Adults ◽

Social Environment ◽

Social Mobility ◽

Socioeconomic Position ◽

Principal Component ◽

Socioeconomic Mobility ◽

Related Factors ◽

Prospective Study Design

ObjectivesImmune response to cytomegalovirus (CMV) impacts adult chronic disease. This study investigates associations of childhood and adulthood social environment, socioeconomic position (SEP) and social mobility with CMV response in young adults.DesignHistorical prospective study design.SettingSubcohort of all 17 003 births to residents of Jerusalem between 1974 and 1976.ParticipantsParticipants included 1319 young adults born in Jerusalem with extensive archival and follow-up data, including childhood and adulthood SEP-related factors and anti-CMV IgG titre levels and seroprevalence measured at age 32.Main exposure and outcome measuresPrincipal component analysis was used to transform correlated social environment and SEP-related variables at two time points (childhood and adulthood) into two major scores reflecting household (eg, number of siblings/children, religiosity) and socioeconomic (eg, occupation, education) components. Based on these components, social mobility variables were created. Linear and Poisson regression models were used to investigate associations of components and mobility with anti-CMV IgG titre level and seroprevalence, adjusted for confounders.ResultsLower levels of household and socioeconomic components in either childhood or adulthood were associated with higher anti-CMV IgG titre level and seropositivity at age 32. Compared with individuals with stable favourable components, anti-CMV IgG titre level and risk for seropositivity were higher in stable unfavourable household and socioeconomic components (household: β=3.23, P<0.001; relative risk (RR)=1.21, P<0.001; socioeconomic: β=2.20, P=0.001; RR=1.14, P=0.01), downward household mobility (β=4.32, P<0.001; RR=1.26, P<0.001) and upward socioeconomic mobility (β=1.37, P=0.04; RR=1.19, P<0.001). Among seropositive individuals, associations between household components and mobility with anti-CMV IgG titre level were maintained and associations between socioeconomic components and mobility with anti-CMV IgG titre level were attenuated.ConclusionsOur study provides evidence that accumulating low SEP from childhood through adulthood and social mobility may compromise immune response in young adulthood.

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