scholarly journals Study on the application of ultrasonography in the diagnosis of fetal cardiac structural abnormalities and the relationship between fetal cardiac structural abnormalities with chromosome abnormalities in early pregnancy

2021 ◽  
Vol 9 (24) ◽  
pp. 1790-1790
Author(s):  
Xueqin Ji ◽  
Yan Xia ◽  
Hao Zhang ◽  
Hairui Wang ◽  
Ruixian Shi ◽  
...  
2016 ◽  
Vol 3 (2) ◽  
pp. 147 ◽  
Author(s):  
Lei CHENG ◽  
Youdong XIN ◽  
Xiaohua LIU ◽  
Xiuzhong HU ◽  
Min XIANG ◽  
...  

1972 ◽  
Vol 53 (2) ◽  
pp. 295-301 ◽  
Author(s):  
F. R. BLATCHLEY ◽  
B. T. DONOVAN

SUMMARY In mated guinea-pigs one uterine horn was rendered sterile by ligation of the oviduct 2 or 3 days after finding spermatozoa in the vaginal smear. Two glass beads were inserted into the sterile horn on each of days 3–12 and on day 14 in experimental animals but not in controls. At autopsy on day 20 large corpora lutea were present in both ovaries of the control animals. The presence of beads that had been introduced on days 3 and 4 and on days 10–14 resulted in marked regression of the corpora lutea in the adjacent ovary, in the absence of a decidual reaction in the uterus, while luteal enlargement typical of pregnancy occurred in the contralateral ovary. Beads inserted on days 5–8 caused decidualization in the sterile horn but did not induce premature luteal regression in the ipsilateral ovary.


Nutrients ◽  
2019 ◽  
Vol 11 (9) ◽  
pp. 2190 ◽  
Author(s):  
Allman ◽  
Diaz Fuentes ◽  
Williams ◽  
Turner ◽  
Andres ◽  
...  

The purpose of this study was to determine the associations between amount and type of dietary protein intake and insulin sensitivity in late pregnancy, in normal weight and overweight women (29.8 ± 0.2 weeks gestation, n = 173). A 100-gram oral glucose tolerance test (OGTT) was administered following an overnight fast to estimate the metabolic clearance rate of glucose (MCR, mg · kg-1 · min-1) using four different equations accounting for the availability of blood samples. Total (TP), animal (AP), and plant (PP) protein intakes were assessed using a 3-day food record. Two linear models with MCR as the response variable were fitted to the data to estimate the relationship of protein intake to insulin sensitivity either unadjusted or adjusted for early pregnancy body mass index (BMI) because of the potential of BMI to influence this relationship. There was a positive association between TP (β = 1.37, p = 0.002) and PP (β = 4.44, p < 0.001) intake in the last trimester of pregnancy and insulin sensitivity that weakened when accounting for early pregnancy BMI. However, there was no relationship between AP intake and insulin sensitivity (β = 0.95, p = 0.08). Therefore, early pregnancy BMI may be a better predictor of insulin sensitivity than dietary protein intake in late pregnancy.


e-CliniC ◽  
2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Rut C.F. Weku ◽  
John J.E. Wantania ◽  
Joice M.M Sondakh

Abstract: Maternal nutritional status is very important for the outcomes of pregnancy. The best indicator for measuring the nutritional status is Body Mass Index (BMI). Abnormal BMI in early pregnancy is associated with various complications for the mother as well as the baby. This study was aimed to obtain the relationship between BMI in early pregnancy and maternal and neonatal outcomes. This was a retrospective analytical study with a cross sectional study. The results showed that there was a siginificant relationship between BMI in early pregnancy and blood pressure (p=0.049), but there was no significant relationship between BMI in early pregnancy and mode of delivery (p=0.067), birth (p=0.100), infant mortality (0.377), and APGAR score (p=0.100). Conclusion: Pregnant woman with BMI ≥25 kg/m2 had a risk of hypertension in pregnancy and a sectio caesarea in delivery; and the baby showed a tendency of low birth weight, risk to death, and asphyxia.Keywords: BMI, pregnancy and maternal neonatal outcomes Abstrak: Status gizi ibu sangat penting terhadap luaran kehamilan. Indikator untuk mengukur status gizi ialah Indeks Massa Tubuh (IMT). Ibu dengan IMT awal kehamilan yang tidak dalam batas normal berkaitan dengan berbagai komplikasi baik terhadap ibu maupun bayi. Penelitian ini bertujuan untuk mengetahui hubungan antara IMT awal kehamilan dengan luaran maternal neonatal. Jenis penelitian ialah analitik-retrospektif dengan desain potong lintang. Hasil penelitian mendapatkan bahwa IMT awal kehamilan berhubungan bermakna dengan tekanan darah (p=0,049), tetapi tidak ditemukan hubungan bermakna antara IMT awal kehamilan dengan cara persalinan (p=0,069), berat badan lahir bayi (p=1,000), kematian bayi (p=0,377), dan APGAR skor (p=1,000). Simpulan: Ibu dengan IMT≥25 kg/m2 berisiko mengalami hipertensi dalam kehamilan, cenderung menjalani persalinan dengan seksio sesarea, dan bayinya cenderung memiliki berat badan lahir rendah, mengalami kematian, dan asfiksia. Kata kunci: IMT, kehamilan dan luaran maternal neonatal.


Nutrients ◽  
2018 ◽  
Vol 10 (9) ◽  
pp. 1152 ◽  
Author(s):  
Alan Leviton

Consumption of coffee by women early in their pregnancy has been viewed as potentially increasing the risk of miscarriage, low birth weight, and childhood leukemias. Many of these reports of epidemiologic studies have not acknowledged the potential biases inherent in studying the relationship between early-pregnancy-coffee consumption and subsequent events. I discuss five of these biases, recall bias, misclassification, residual confounding, reverse causation, and publication bias. Each might account for claims that attribute adversities to early-pregnancy-coffee consumption. To what extent these biases can be avoided remains to be determined. As a minimum, these biases need to be acknowledged wherever they might account for what is reported.


2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Amy E. Clipperton-Allen ◽  
Ori S. Cohen ◽  
Massimiliano Aceti ◽  
Aya Zucca ◽  
Jenna Levy ◽  
...  

AbstractHaploinsufficiency for PTEN is a cause of autism spectrum disorder and brain overgrowth; however, it is not known if PTEN mutations disrupt scaling across brain areas during development. To address this question, we used magnetic resonance imaging to analyze brains of male Pten haploinsufficient (Pten+/−) mice and wild-type littermates during early postnatal development and adulthood. Adult Pten+/− mice display a consistent pattern of abnormal scaling across brain areas, with white matter (WM) areas being particularly affected. This regional and WM enlargement recapitulates structural abnormalities found in individuals with PTEN haploinsufficiency and autism. Early postnatal Pten+/− mice do not display the same pattern, instead exhibiting greater variability across mice and brain regions than controls. This suggests that Pten haploinsufficiency may desynchronize growth across brain regions during early development before stabilizing by maturity. Pten+/− cortical cultures display increased proliferation of glial cell populations, indicating a potential substrate of WM enlargement, and provide a platform for testing candidate therapeutics. Pten haploinsufficiency dysregulates coordinated growth across brain regions during development. This results in abnormally scaled brain areas and associated behavioral deficits, potentially explaining the relationship between PTEN mutations and neurodevelopmental disorders.


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